NO20092742L - 4,5-ringkondenserte indolderivater for behandling eller forebyggelse av HCV og beslektede virusinfeksjoner - Google Patents
4,5-ringkondenserte indolderivater for behandling eller forebyggelse av HCV og beslektede virusinfeksjonerInfo
- Publication number
- NO20092742L NO20092742L NO20092742A NO20092742A NO20092742L NO 20092742 L NO20092742 L NO 20092742L NO 20092742 A NO20092742 A NO 20092742A NO 20092742 A NO20092742 A NO 20092742A NO 20092742 L NO20092742 L NO 20092742L
- Authority
- NO
- Norway
- Prior art keywords
- prevention
- ring condensed
- treatment
- indole derivatives
- hcv
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87687706P | 2006-12-22 | 2006-12-22 | |
PCT/US2007/025754 WO2008082484A1 (en) | 2006-12-22 | 2007-12-17 | 4,5-ring annulated indole derivatives for treating or preventing of hcv and related viral infections |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20092742L true NO20092742L (no) | 2009-09-21 |
Family
ID=39186835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20092742A NO20092742L (no) | 2006-12-22 | 2009-07-21 | 4,5-ringkondenserte indolderivater for behandling eller forebyggelse av HCV og beslektede virusinfeksjoner |
Country Status (18)
Country | Link |
---|---|
US (1) | US8557848B2 (es) |
EP (1) | EP2064180B1 (es) |
JP (1) | JP5079818B2 (es) |
KR (1) | KR20090094154A (es) |
CN (1) | CN101631773A (es) |
AR (1) | AR064428A1 (es) |
AU (1) | AU2007339382B2 (es) |
BR (1) | BRPI0720625A2 (es) |
CA (1) | CA2673249C (es) |
CL (1) | CL2007003686A1 (es) |
CO (1) | CO6190515A2 (es) |
EC (1) | ECSP099447A (es) |
MX (1) | MX2009006880A (es) |
NO (1) | NO20092742L (es) |
PE (1) | PE20081608A1 (es) |
RU (1) | RU2009127855A (es) |
TW (1) | TW200831496A (es) |
WO (1) | WO2008082484A1 (es) |
Families Citing this family (39)
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US20110104109A1 (en) * | 2005-07-13 | 2011-05-05 | Frank Bennett | Tetracyclic indole derivatives and their use for treating or preventing viral infections |
WO2008082488A1 (en) | 2006-12-22 | 2008-07-10 | Schering Corporation | 4, 5-ring annulated indole derivatives for treating or preventing of hcv and related viral infections |
RU2009127855A (ru) | 2006-12-22 | 2011-01-27 | Шеринг Корпорейшн (US) | 4,5 циклоаннелированные производные индола для лечения или предотвращения вируса гепатита с (hcv) и родственных вирусных инфекций |
CN101611025A (zh) | 2006-12-22 | 2009-12-23 | 先灵公司 | 5,6-环化的吲哚衍生物及其使用方法 |
KR20100067652A (ko) | 2007-08-29 | 2010-06-21 | 쉐링 코포레이션 | 치환된 인돌 유도체 및 이의 사용방법 |
CN101842374A (zh) | 2007-08-29 | 2010-09-22 | 先灵公司 | 用于治疗病毒感染的2,3-取代的氮杂吲哚衍生物 |
CN101842353A (zh) | 2007-08-29 | 2010-09-22 | 先灵公司 | 用于治疗病毒感染的2,3-取代的吲哚衍生物 |
US8377928B2 (en) | 2007-11-16 | 2013-02-19 | Merck Sharp & Dohme Corp. | 3-aminosulfonyl substituted indole derivatives and methods of use thereof |
CA2705586A1 (en) | 2007-11-16 | 2009-05-22 | Schering Corporation | 3-heterocyclic substituted indole derivatives and methods of use thereof |
US8901139B2 (en) | 2008-06-13 | 2014-12-02 | Merck Sharp & Dohme Corp. | Tricyclic indole derivatives and methods of use thereof |
EP2334662A1 (en) * | 2008-09-26 | 2011-06-22 | F. Hoffmann-La Roche AG | Pyrine or pyrazine derivatives for treating hcv |
KR20110094352A (ko) | 2008-12-22 | 2011-08-23 | 에프. 호프만-라 로슈 아게 | 헤테로사이클릭 항바이러스 화합물 |
TW201035083A (en) * | 2009-03-06 | 2010-10-01 | Hoffmann La Roche | Heterocyclic antiviral compounds |
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CA2785488A1 (en) | 2009-12-22 | 2011-07-21 | Merck Sharp & Dohme Corp. | Fused tricyclic compounds and methods of use thereof for the treatment of viral diseases |
PE20130062A1 (es) | 2010-03-09 | 2013-02-28 | Merck Sharp & Dohme | Compuestos de sililo triciclicos fusionados para el tratamiento de enfermedades virales |
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US9156872B2 (en) | 2011-04-13 | 2015-10-13 | Merck Sharp & Dohme Corp. | 2′-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases |
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WO2013033900A1 (en) | 2011-09-08 | 2013-03-14 | Merck Sharp & Dohme Corp. | Tetracyclic heterocycle compounds and methods of use thereof for the treatment of viral diseases |
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AR092959A1 (es) | 2012-10-17 | 2015-05-06 | Merck Sharp & Dohme | Derivados de nucleosidos 2-metil sustituidos y metodos de uso de los mismos para el tratamiento de enfermedades virales |
US9457039B2 (en) | 2012-10-17 | 2016-10-04 | Merck Sharp & Dohme Corp. | 2′-disubstituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases |
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RU2015123641A (ru) | 2012-11-19 | 2017-01-10 | Мерк Шарп И Доум Корп. | 2-алкинилзамещенные производные нуклеозидов, предназначенные для лечения вирусных заболеваний |
WO2014205593A1 (en) | 2013-06-24 | 2014-12-31 | Merck Sharp & Dohme Corp. | Substituted benzofuran compounds and methods of use thereof for treatment of viral diseases |
WO2014205592A1 (en) | 2013-06-24 | 2014-12-31 | Merck Sharp & Dohme Corp. | Heterocyclic compounds and methods of use thereof for treatment of hepatitis c |
WO2015065817A1 (en) | 2013-10-30 | 2015-05-07 | Merck Sharp & Dohme Corp. | Pseudopolymorphs of an hcv ns5a inhibitor and uses thereof |
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WO2008082488A1 (en) | 2006-12-22 | 2008-07-10 | Schering Corporation | 4, 5-ring annulated indole derivatives for treating or preventing of hcv and related viral infections |
RU2009127855A (ru) | 2006-12-22 | 2011-01-27 | Шеринг Корпорейшн (US) | 4,5 циклоаннелированные производные индола для лечения или предотвращения вируса гепатита с (hcv) и родственных вирусных инфекций |
CN101842353A (zh) | 2007-08-29 | 2010-09-22 | 先灵公司 | 用于治疗病毒感染的2,3-取代的吲哚衍生物 |
CN101842374A (zh) | 2007-08-29 | 2010-09-22 | 先灵公司 | 用于治疗病毒感染的2,3-取代的氮杂吲哚衍生物 |
KR20100067652A (ko) | 2007-08-29 | 2010-06-21 | 쉐링 코포레이션 | 치환된 인돌 유도체 및 이의 사용방법 |
CA2705586A1 (en) | 2007-11-16 | 2009-05-22 | Schering Corporation | 3-heterocyclic substituted indole derivatives and methods of use thereof |
US8377928B2 (en) | 2007-11-16 | 2013-02-19 | Merck Sharp & Dohme Corp. | 3-aminosulfonyl substituted indole derivatives and methods of use thereof |
US8901139B2 (en) | 2008-06-13 | 2014-12-02 | Merck Sharp & Dohme Corp. | Tricyclic indole derivatives and methods of use thereof |
-
2007
- 2007-12-17 RU RU2009127855/04A patent/RU2009127855A/ru not_active Application Discontinuation
- 2007-12-17 BR BRPI0720625-9A2A patent/BRPI0720625A2/pt not_active Application Discontinuation
- 2007-12-17 WO PCT/US2007/025754 patent/WO2008082484A1/en active Application Filing
- 2007-12-17 US US12/519,715 patent/US8557848B2/en active Active
- 2007-12-17 AU AU2007339382A patent/AU2007339382B2/en active Active
- 2007-12-17 KR KR1020097015298A patent/KR20090094154A/ko not_active Application Discontinuation
- 2007-12-17 CN CN200780051419A patent/CN101631773A/zh active Pending
- 2007-12-17 JP JP2009542835A patent/JP5079818B2/ja not_active Expired - Fee Related
- 2007-12-17 MX MX2009006880A patent/MX2009006880A/es unknown
- 2007-12-17 CA CA2673249A patent/CA2673249C/en active Active
- 2007-12-17 EP EP07862998.7A patent/EP2064180B1/en active Active
- 2007-12-18 CL CL200703686A patent/CL2007003686A1/es unknown
- 2007-12-18 AR ARP070105705A patent/AR064428A1/es not_active Application Discontinuation
- 2007-12-18 TW TW096148504A patent/TW200831496A/zh unknown
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2008
- 2008-01-02 PE PE2008000053A patent/PE20081608A1/es not_active Application Discontinuation
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2009
- 2009-06-18 CO CO09063496A patent/CO6190515A2/es not_active Application Discontinuation
- 2009-06-19 EC EC2009009447A patent/ECSP099447A/es unknown
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Also Published As
Publication number | Publication date |
---|---|
JP2010513490A (ja) | 2010-04-30 |
KR20090094154A (ko) | 2009-09-03 |
CL2007003686A1 (es) | 2008-06-27 |
BRPI0720625A2 (pt) | 2014-03-25 |
US8557848B2 (en) | 2013-10-15 |
ECSP099447A (es) | 2009-07-31 |
CA2673249C (en) | 2013-04-30 |
CO6190515A2 (es) | 2010-08-19 |
WO2008082484A1 (en) | 2008-07-10 |
JP5079818B2 (ja) | 2012-11-21 |
AU2007339382A1 (en) | 2008-07-10 |
EP2064180A1 (en) | 2009-06-03 |
AR064428A1 (es) | 2009-04-01 |
RU2009127855A (ru) | 2011-01-27 |
CA2673249A1 (en) | 2008-07-10 |
CN101631773A (zh) | 2010-01-20 |
EP2064180B1 (en) | 2016-07-13 |
US20100098661A1 (en) | 2010-04-22 |
PE20081608A1 (es) | 2008-11-12 |
AU2007339382B2 (en) | 2013-05-02 |
MX2009006880A (es) | 2009-07-03 |
TW200831496A (en) | 2008-08-01 |
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