NO20092636L - Ikke-nukleosid-reverstranskriptaseinhibitorer - Google Patents

Ikke-nukleosid-reverstranskriptaseinhibitorer

Info

Publication number
NO20092636L
NO20092636L NO20092636A NO20092636A NO20092636L NO 20092636 L NO20092636 L NO 20092636L NO 20092636 A NO20092636 A NO 20092636A NO 20092636 A NO20092636 A NO 20092636A NO 20092636 L NO20092636 L NO 20092636L
Authority
NO
Norway
Prior art keywords
reverse transcriptase
transcriptase inhibitors
compounds
nucleoside reverse
prophylaxis
Prior art date
Application number
NO20092636A
Other languages
English (en)
Inventor
Neville J Anthony
Robert Gomez
Samson M Jolly
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO20092636L publication Critical patent/NO20092636L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Forbindelser med formel (I) er HIV-reverstranskriptaseinhibitorer, hvor Q, R2, R3, R6, T1, T2 og T3 er som definert her. Forbindelsene med formel (I) og farmasøytisk akseptable salter og prolegemidler derav, er anvendelige til inhibering av HIV-reverstranskriptase, profylakse og behandling av infeksjon med HIV, og ved profylakse, forsinkelse i start eller utvikling og behandling av AIDS. Forbindelsene og deres salter kan benyttes som ingredienser i farmasøytiske preparater, eventuelt i kombinasjon med andre antiviraler, immunmodulatorer, antibiotika eller vaksiner.
NO20092636A 2006-12-13 2009-07-10 Ikke-nukleosid-reverstranskriptaseinhibitorer NO20092636L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87462906P 2006-12-13 2006-12-13
PCT/US2007/024974 WO2008076223A1 (en) 2006-12-13 2007-12-06 Non-nucleoside reverse transcriptase inhibitors

Publications (1)

Publication Number Publication Date
NO20092636L true NO20092636L (no) 2009-09-08

Family

ID=39277099

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092636A NO20092636L (no) 2006-12-13 2009-07-10 Ikke-nukleosid-reverstranskriptaseinhibitorer

Country Status (29)

Country Link
US (2) US7781454B2 (no)
EP (1) EP2121638B1 (no)
JP (1) JP5123949B2 (no)
KR (1) KR20090087481A (no)
CN (1) CN101558050A (no)
AR (1) AR064199A1 (no)
AU (1) AU2007334598B2 (no)
BR (1) BRPI0720196A2 (no)
CA (1) CA2673093A1 (no)
CL (1) CL2007003594A1 (no)
CR (1) CR10843A (no)
DO (1) DOP2009000138A (no)
EA (1) EA200970572A1 (no)
EC (1) ECSP099373A (no)
GE (1) GEP20115320B (no)
GT (1) GT200900158A (no)
HN (1) HN2009001160A (no)
IL (1) IL199103A0 (no)
MA (1) MA31036B1 (no)
MX (1) MX2009006285A (no)
NI (1) NI200900103A (no)
NO (1) NO20092636L (no)
NZ (1) NZ577637A (no)
PE (1) PE20081448A1 (no)
SV (1) SV2009003294A (no)
TN (1) TN2009000243A1 (no)
TW (1) TW200831085A (no)
WO (2) WO2008076223A1 (no)
ZA (1) ZA200903395B (no)

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Also Published As

Publication number Publication date
WO2008076225A2 (en) 2008-06-26
MA31036B1 (fr) 2009-12-01
US20080275097A1 (en) 2008-11-06
CA2673093A1 (en) 2008-06-26
GT200900158A (es) 2009-10-14
IL199103A0 (en) 2010-03-28
AR064199A1 (es) 2009-03-18
ECSP099373A (es) 2009-07-31
EP2121638B1 (en) 2016-05-25
AU2007334598A1 (en) 2008-06-26
BRPI0720196A2 (pt) 2013-12-31
CL2007003594A1 (es) 2008-05-30
CR10843A (es) 2009-08-12
AU2007334598B2 (en) 2013-01-17
HN2009001160A (es) 2011-10-11
MX2009006285A (es) 2009-06-23
JP5123949B2 (ja) 2013-01-23
SV2009003294A (es) 2009-11-09
US20100286192A1 (en) 2010-11-11
NZ577637A (en) 2011-05-27
NI200900103A (es) 2010-01-26
TN2009000243A1 (en) 2010-10-18
WO2008076225A3 (en) 2008-08-07
TW200831085A (en) 2008-08-01
EA200970572A1 (ru) 2009-12-30
EP2121638A2 (en) 2009-11-25
GEP20115320B (en) 2011-10-25
ZA200903395B (en) 2010-05-26
CN101558050A (zh) 2009-10-14
US7781454B2 (en) 2010-08-24
WO2008076223A1 (en) 2008-06-26
DOP2009000138A (es) 2009-11-15
KR20090087481A (ko) 2009-08-17
JP2010510989A (ja) 2010-04-08
PE20081448A1 (es) 2008-10-19

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