NO20091419L - Fenyleddiksyrederivat - Google Patents

Fenyleddiksyrederivat

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Publication number
NO20091419L
NO20091419L NO20091419A NO20091419A NO20091419L NO 20091419 L NO20091419 L NO 20091419L NO 20091419 A NO20091419 A NO 20091419A NO 20091419 A NO20091419 A NO 20091419A NO 20091419 L NO20091419 L NO 20091419L
Authority
NO
Norway
Prior art keywords
group
alkyl
hydrogen atom
halogen
alkoxyl
Prior art date
Application number
NO20091419A
Other languages
English (en)
Inventor
Hideo Kato
Hiroshi Nakamura
Osamu Nagata
Yoshiyuki Iwabuchi
Takahiro Sato
Junichiro Uda
Tutomu Inoue
Nobuhide Kawasaki
Ippei Tanaka
Naoki Kurita
Tomohiko Ishikawa
Original Assignee
Fuji Yakuhin Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fuji Yakuhin Co Ltd filed Critical Fuji Yakuhin Co Ltd
Publication of NO20091419L publication Critical patent/NO20091419L/no

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D333/32—Oxygen atoms
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    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
    • C07D333/48—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom by oxygen atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)

Abstract

Forbindelse med forrnel (1) eller et salt derav som har en overlegen inhiberende virkning på produksjonen av prostaglandin E2 og er anvendelig som en aktiv ingrediens i et farmasøytisk middel med reduserte bivirkninger, så som gastrointestinale forstyrrelser, hvor ---- representerer enkeltbinding eller dobbeltbinding; W er hydrogenatom eller alkylgruppe; R2 og R3 er hydrogenatom eller alkylgruppe; R4 og R5 er hydrogenatom, hydroksygruppe, alkoksylgruppe, halogen eller mono- eller di-alkylsubstituert aminogruppe; R6 er hydrogenatom, cyanogruppe, alkoksykarbonylgruppe eller karboksygruppe; R7 representerer én eller to substituenter på benzenringen, valgt blant hydrogen, halogen, nitro, cyano, hydroksy, amino, alkyl og alkoksyl, A representerer en 5- eller 6-leddet heterosyklisk ring som inneholder ett eller to tilgrensende svovelatomer som uavhengig av til hverandre kan danne oksid, W---- representerer en oksogruppe, hydrogen, alkyl, hydroksy, alkoksyl eller halogen, og X representerer oksygen eller svovel.
NO20091419A 2006-09-11 2009-04-07 Fenyleddiksyrederivat NO20091419L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006245194 2006-09-11
PCT/JP2007/067568 WO2008032665A1 (fr) 2006-09-11 2007-09-10 Nouveau dérivé de l'acide phénylacétique

Publications (1)

Publication Number Publication Date
NO20091419L true NO20091419L (no) 2009-05-20

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NO20091419A NO20091419L (no) 2006-09-11 2009-04-07 Fenyleddiksyrederivat

Country Status (19)

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US (1) US8148421B2 (no)
EP (1) EP2062884B1 (no)
JP (1) JP4538072B2 (no)
KR (1) KR101360579B1 (no)
CN (1) CN101535289B (no)
AR (1) AR062723A1 (no)
AU (1) AU2007295510B2 (no)
BR (1) BRPI0716550A2 (no)
CA (1) CA2663234C (no)
ES (1) ES2402377T3 (no)
IL (1) IL197506A0 (no)
IN (1) IN2009CN01906A (no)
MX (1) MX2009002692A (no)
NO (1) NO20091419L (no)
NZ (1) NZ575635A (no)
RU (1) RU2414465C2 (no)
TW (1) TW200827343A (no)
WO (1) WO2008032665A1 (no)
ZA (1) ZA200901988B (no)

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CN101704777B (zh) * 2009-10-18 2012-10-31 伊泰(北京)合成技术有限公司 一种去除前列素类化合物5，6位反式双键异构体的方法
CN116239498B (zh) * 2023-05-11 2023-07-21 北京元延医药科技股份有限公司 制备克立硼罗中间体的方法
CN116253756B (zh) * 2023-05-11 2023-07-18 北京元延医药科技股份有限公司 克立硼罗的制备方法

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EP2062884A4 (en) 2011-11-09
JPWO2008032665A1 (ja) 2010-01-28
JP4538072B2 (ja) 2010-09-08
US20100048666A1 (en) 2010-02-25
WO2008032665A1 (fr) 2008-03-20
IN2009CN01906A (no) 2015-08-07
KR20090061034A (ko) 2009-06-15
NZ575635A (en) 2011-08-26
TW200827343A (en) 2008-07-01
CA2663234C (en) 2014-08-05
AU2007295510A1 (en) 2008-03-20
AR062723A1 (es) 2008-11-26
CN101535289B (zh) 2013-06-05
EP2062884B1 (en) 2013-02-20
KR101360579B1 (ko) 2014-02-10
RU2009113546A (ru) 2010-10-20
CN101535289A (zh) 2009-09-16
CA2663234A1 (en) 2008-03-20
ES2402377T3 (es) 2013-05-03
MX2009002692A (es) 2009-03-30
ZA200901988B (en) 2010-06-30
BRPI0716550A2 (pt) 2013-09-24
AU2007295510B2 (en) 2011-09-01
US8148421B2 (en) 2012-04-03
IL197506A0 (en) 2009-12-24
RU2414465C2 (ru) 2011-03-20
EP2062884A1 (en) 2009-05-27

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