NO20083382L - Reduksjon av 5-(aryl-diazenyl)-4,6-dihalogen-pyrimidin - Google Patents

Reduksjon av 5-(aryl-diazenyl)-4,6-dihalogen-pyrimidin

Info

Publication number
NO20083382L
NO20083382L NO20083382A NO20083382A NO20083382L NO 20083382 L NO20083382 L NO 20083382L NO 20083382 A NO20083382 A NO 20083382A NO 20083382 A NO20083382 A NO 20083382A NO 20083382 L NO20083382 L NO 20083382L
Authority
NO
Norway
Prior art keywords
compound
formula
diazenyl
dihalo
pyrimidine
Prior art date
Application number
NO20083382A
Other languages
English (en)
Norwegian (no)
Inventor
Wilhelm Quittmann
Wei Zhu
Feng Ye
Rongmin Chen
Original Assignee
Lonza Guangzhou Res And Dev Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Guangzhou Res And Dev Ct filed Critical Lonza Guangzhou Res And Dev Ct
Publication of NO20083382L publication Critical patent/NO20083382L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
NO20083382A 2006-02-13 2008-08-05 Reduksjon av 5-(aryl-diazenyl)-4,6-dihalogen-pyrimidin NO20083382L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06002822 2006-02-13
EP06009627 2006-05-10
PCT/EP2007/001216 WO2007093368A1 (en) 2006-02-13 2007-02-13 Reduction of 5-(aryl-diazenyl)-4,6-dihalo-pyrimidine

Publications (1)

Publication Number Publication Date
NO20083382L true NO20083382L (no) 2008-08-27

Family

ID=37909713

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083382A NO20083382L (no) 2006-02-13 2008-08-05 Reduksjon av 5-(aryl-diazenyl)-4,6-dihalogen-pyrimidin

Country Status (17)

Country Link
US (2) US8114996B2 (zh)
EP (1) EP1987012B1 (zh)
JP (1) JP5275046B2 (zh)
CN (1) CN101384561B (zh)
AT (1) ATE466845T1 (zh)
AU (1) AU2007214713B2 (zh)
BR (1) BRPI0707725A2 (zh)
CA (1) CA2636619A1 (zh)
DE (1) DE602007006281D1 (zh)
ES (1) ES2345287T3 (zh)
HK (1) HK1128465A1 (zh)
NO (1) NO20083382L (zh)
PL (1) PL1987012T3 (zh)
PT (1) PT1987012E (zh)
SI (1) SI1987012T1 (zh)
TW (1) TWI385156B (zh)
WO (1) WO2007093368A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130726A (zh) * 2013-02-07 2013-06-05 许学农 替卡格雷中间体4,6-二氯-2-(丙巯基)-5-氨基嘧啶的制备方法
WO2014206187A1 (zh) 2013-06-24 2014-12-31 苏州明锐医药科技有限公司 替卡格雷及其中间体的制备方法
CN104610237B (zh) * 2013-11-05 2018-03-30 正大天晴药业集团股份有限公司 一种替格瑞洛的制备方法及其中间体
CN103923020A (zh) * 2014-04-02 2014-07-16 黄河三角洲京博化工研究院有限公司 一种2-丙硫基-4,6-二氯-5-氨基嘧啶的制备方法
CN105294573B (zh) * 2015-06-16 2018-07-10 厦门医学院 一种合成4,6-二氯-2-(丙硫基)-5-氨基嘧啶的方法
CN111763175A (zh) * 2020-07-23 2020-10-13 广州康瑞泰药业有限公司 4,6-二氯-2-(硫丙基)-5-氨基嘧啶的纯化方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6393760A (ja) * 1986-10-08 1988-04-25 Kemipuro Kasei Kk 芳香族ヒドラゾ化合物の製造法
SE0401001D0 (sv) * 2004-03-31 2004-03-31 Astrazeneca Ab Chemical process

Also Published As

Publication number Publication date
PT1987012E (pt) 2010-07-16
ATE466845T1 (de) 2010-05-15
AU2007214713A1 (en) 2007-08-23
EP1987012B1 (en) 2010-05-05
TWI385156B (zh) 2013-02-11
BRPI0707725A2 (pt) 2011-05-10
US20120130058A1 (en) 2012-05-24
DE602007006281D1 (de) 2010-06-17
HK1128465A1 (zh) 2009-10-30
TW200740772A (en) 2007-11-01
CN101384561B (zh) 2012-01-04
SI1987012T1 (sl) 2010-09-30
EP1987012A1 (en) 2008-11-05
JP2009526796A (ja) 2009-07-23
AU2007214713B2 (en) 2011-09-01
CN101384561A (zh) 2009-03-11
WO2007093368A1 (en) 2007-08-23
AU2007214713A8 (en) 2008-08-28
US8114996B2 (en) 2012-02-14
JP5275046B2 (ja) 2013-08-28
CA2636619A1 (en) 2007-08-23
ES2345287T3 (es) 2010-09-20
PL1987012T3 (pl) 2010-11-30
US20110178298A1 (en) 2011-07-21

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Legal Events

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