HK1128465A1 - - Google Patents

Info

Publication number
HK1128465A1
HK1128465A1 HK09106202.2A HK09106202A HK1128465A1 HK 1128465 A1 HK1128465 A1 HK 1128465A1 HK 09106202 A HK09106202 A HK 09106202A HK 1128465 A1 HK1128465 A1 HK 1128465A1
Authority
HK
Hong Kong
Prior art keywords
compound
formula
catalytically
hydrazo
catalyst
Prior art date
Application number
HK09106202.2A
Other languages
English (en)
Inventor
Wilhelm Quittmann
Wei Zhu
Feng Ye
Rongmin Chen
Original Assignee
Lonza Ag
Lonza Guangzhou Res & Dev Ct Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag, Lonza Guangzhou Res & Dev Ct Ltd filed Critical Lonza Ag
Publication of HK1128465A1 publication Critical patent/HK1128465A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
HK09106202.2A 2006-02-13 2009-07-10 HK1128465A1 (xx)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06002822 2006-02-13
EP06009627 2006-05-10
PCT/EP2007/001216 WO2007093368A1 (en) 2006-02-13 2007-02-13 Reduction of 5-(aryl-diazenyl)-4,6-dihalo-pyrimidine

Publications (1)

Publication Number Publication Date
HK1128465A1 true HK1128465A1 (xx) 2009-10-30

Family

ID=37909713

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09106202.2A HK1128465A1 (xx) 2006-02-13 2009-07-10

Country Status (17)

Country Link
US (2) US8114996B2 (xx)
EP (1) EP1987012B1 (xx)
JP (1) JP5275046B2 (xx)
CN (1) CN101384561B (xx)
AT (1) ATE466845T1 (xx)
AU (1) AU2007214713B2 (xx)
BR (1) BRPI0707725A2 (xx)
CA (1) CA2636619A1 (xx)
DE (1) DE602007006281D1 (xx)
ES (1) ES2345287T3 (xx)
HK (1) HK1128465A1 (xx)
NO (1) NO20083382L (xx)
PL (1) PL1987012T3 (xx)
PT (1) PT1987012E (xx)
SI (1) SI1987012T1 (xx)
TW (1) TWI385156B (xx)
WO (1) WO2007093368A1 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130726A (zh) * 2013-02-07 2013-06-05 许学农 替卡格雷中间体4,6-二氯-2-(丙巯基)-5-氨基嘧啶的制备方法
WO2014206187A1 (zh) 2013-06-24 2014-12-31 苏州明锐医药科技有限公司 替卡格雷及其中间体的制备方法
CN104610237B (zh) * 2013-11-05 2018-03-30 正大天晴药业集团股份有限公司 一种替格瑞洛的制备方法及其中间体
CN103923020A (zh) * 2014-04-02 2014-07-16 黄河三角洲京博化工研究院有限公司 一种2-丙硫基-4,6-二氯-5-氨基嘧啶的制备方法
CN105294573B (zh) * 2015-06-16 2018-07-10 厦门医学院 一种合成4,6-二氯-2-(丙硫基)-5-氨基嘧啶的方法
CN111763175A (zh) * 2020-07-23 2020-10-13 广州康瑞泰药业有限公司 4,6-二氯-2-(硫丙基)-5-氨基嘧啶的纯化方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6393760A (ja) * 1986-10-08 1988-04-25 Kemipuro Kasei Kk 芳香族ヒドラゾ化合物の製造法
SE0401001D0 (sv) * 2004-03-31 2004-03-31 Astrazeneca Ab Chemical process

Also Published As

Publication number Publication date
BRPI0707725A2 (pt) 2011-05-10
WO2007093368A1 (en) 2007-08-23
ATE466845T1 (de) 2010-05-15
US8114996B2 (en) 2012-02-14
AU2007214713A1 (en) 2007-08-23
NO20083382L (no) 2008-08-27
ES2345287T3 (es) 2010-09-20
CN101384561A (zh) 2009-03-11
SI1987012T1 (sl) 2010-09-30
PL1987012T3 (pl) 2010-11-30
JP2009526796A (ja) 2009-07-23
EP1987012B1 (en) 2010-05-05
US20120130058A1 (en) 2012-05-24
DE602007006281D1 (de) 2010-06-17
EP1987012A1 (en) 2008-11-05
JP5275046B2 (ja) 2013-08-28
AU2007214713A8 (en) 2008-08-28
US20110178298A1 (en) 2011-07-21
CN101384561B (zh) 2012-01-04
TWI385156B (zh) 2013-02-11
CA2636619A1 (en) 2007-08-23
TW200740772A (en) 2007-11-01
PT1987012E (pt) 2010-07-16
AU2007214713B2 (en) 2011-09-01

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160213