NO20082935L - Fremgangsmate for rensing av makrolidantibiotika - Google Patents
Fremgangsmate for rensing av makrolidantibiotikaInfo
- Publication number
- NO20082935L NO20082935L NO20082935A NO20082935A NO20082935L NO 20082935 L NO20082935 L NO 20082935L NO 20082935 A NO20082935 A NO 20082935A NO 20082935 A NO20082935 A NO 20082935A NO 20082935 L NO20082935 L NO 20082935L
- Authority
- NO
- Norway
- Prior art keywords
- macrolide antibiotics
- purifying
- procedure
- purification
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
Den foreliggende oppfinnelse angår en fremgangsmåte for rensingen av makrolidantibiotika. Nærmere bestemt angår oppfinnelsen en fremgangsmåte for rensingen av makrolidantibiotika som resulterer i et hvitt pulver. Pulveret forblir hvitt også etter noe tids lagring. Fremgangsmåten ved den foreliggende oppfinnelse utføres ved å løse makrolidantibiotika, feks. kommersielt vancomycin hydroklorid, i vann og utsette løsningen for ultrafiltrering med en membran som har en normal retensjon som er lavere enn 3000 Da, fortrinnsvis 10000 Da. Den rensede løsningen konsentreres fortrinnsvis ved hjelp av reversert osmose og lyofiliseres deretter ved de optimaliserte betingelser for trykk og temperatur for å oppnå et hvitt pulver.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05112283A EP1798237A1 (en) | 2005-12-16 | 2005-12-16 | Process for the purification of macrolide antibiotics |
PCT/EP2006/069414 WO2007068644A1 (en) | 2005-12-16 | 2006-12-07 | Process for the purification of macrolide antibiotics |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082935L true NO20082935L (no) | 2008-06-30 |
Family
ID=36177625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082935A NO20082935L (no) | 2005-12-16 | 2008-06-30 | Fremgangsmate for rensing av makrolidantibiotika |
Country Status (15)
Country | Link |
---|---|
US (1) | US8268963B2 (no) |
EP (2) | EP1798237A1 (no) |
JP (1) | JP5124475B2 (no) |
CN (1) | CN101341167B (no) |
AT (1) | ATE457994T1 (no) |
AU (1) | AU2006326070B2 (no) |
CA (1) | CA2628798C (no) |
DE (1) | DE602006012360D1 (no) |
DK (1) | DK1960418T3 (no) |
ES (1) | ES2340804T3 (no) |
NO (1) | NO20082935L (no) |
PL (1) | PL1960418T3 (no) |
PT (1) | PT1960418E (no) |
RU (1) | RU2400489C2 (no) |
WO (1) | WO2007068644A1 (no) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101101663B1 (ko) * | 2009-01-13 | 2011-12-30 | (주) 제노텍 | 반코마이신 습체의 정제방법 |
ITLO20110001A1 (it) | 2011-05-03 | 2012-11-04 | Fisiopharma Srl | Flaconi di vancomicina cloroidrata con stabilità migliorata |
EP2592090A1 (en) * | 2011-11-11 | 2013-05-15 | LEK Pharmaceuticals d.d. | Process of purification of teicoplanin |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2288473A1 (fr) * | 1974-10-22 | 1976-05-21 | Manche Union Coop Agr Laiti | Procede de traitement du lactoserum de fromagerie, notamment en vue de l'extraction de glycoproteides et d'acide sialique |
US4667024A (en) * | 1983-07-13 | 1987-05-19 | Smithkline Beckman Corporation | Process for the preparation of purified vancomycin class antibiotics |
CA1245639A (en) * | 1983-12-12 | 1988-11-29 | Lilly Co Eli | PREPARATION OF VANCOMYCIN DIPHOSPHATE |
JPH0260598A (ja) * | 1988-08-22 | 1990-03-01 | Glaxo Group Ltd | 抗生物質の製造 |
JP2577133B2 (ja) * | 1989-11-27 | 1997-01-29 | スティフティング フォール ド テフニスヘ ウェッテンスハッペン | 船舶のプロペラ |
US5258495A (en) * | 1990-07-10 | 1993-11-02 | Abbott Laboratories | Process for making vancomycin HC1 |
SI9500040B (sl) * | 1995-02-07 | 2002-02-28 | Lek, | Kromatografsko čiščenje Vankomicin hidroklorida z uporabo preparativne HPLC |
SI9500039B (sl) | 1995-02-07 | 2002-02-28 | Lek, | Nov kombiniran postopek čiščenja Vankomicin hidroklorida |
JPH10225299A (ja) * | 1996-12-11 | 1998-08-25 | Nippon Kayaku Co Ltd | バンコマイシンの製造方法 |
JP4142149B2 (ja) | 1997-07-10 | 2008-08-27 | 明治製菓株式会社 | バンコマイシンの凍結乾燥製剤 |
EP1025852A4 (en) * | 1997-10-03 | 2001-11-07 | Fujisawa Pharmaceutical Co | VANCOMYCIN ANTIBIOTIC HYDROCHLORIDES AND METHOD FOR THE PRODUCTION THEREOF |
CN1056377C (zh) * | 1998-01-22 | 2000-09-13 | 清华大学 | 用环烷酸萃取体系提取和纯化抗生素 |
KR100870660B1 (ko) * | 2001-12-31 | 2008-11-26 | 엘지디스플레이 주식회사 | 패널의 합착력이 향상된 액정표시소자 및 제조방법 |
KR100476818B1 (ko) * | 2002-07-19 | 2005-03-17 | 종근당바이오 주식회사 | 테이코플라닌 에이 투 정제 방법 |
CN1301331C (zh) | 2003-12-26 | 2007-02-21 | 三达膜科技(厦门)有限公司 | 应用膜提取发酵类大环内酯型抗生素的方法 |
KR100474653B1 (ko) * | 2004-04-16 | 2005-03-14 | 동국제약 주식회사 | 타이코플라닌의 고순도 생산방법 |
SI21924A (sl) | 2004-12-07 | 2006-06-30 | Lek Farmacevtska Druzba D.D. | Cist vankomicin hidroklorid |
-
2005
- 2005-12-16 EP EP05112283A patent/EP1798237A1/en not_active Withdrawn
-
2006
- 2006-12-07 AT AT06841295T patent/ATE457994T1/de active
- 2006-12-07 AU AU2006326070A patent/AU2006326070B2/en not_active Ceased
- 2006-12-07 WO PCT/EP2006/069414 patent/WO2007068644A1/en active Application Filing
- 2006-12-07 DE DE602006012360T patent/DE602006012360D1/de active Active
- 2006-12-07 CN CN200680045911XA patent/CN101341167B/zh not_active Expired - Fee Related
- 2006-12-07 DK DK06841295.6T patent/DK1960418T3/da active
- 2006-12-07 JP JP2008544968A patent/JP5124475B2/ja active Active
- 2006-12-07 PL PL06841295T patent/PL1960418T3/pl unknown
- 2006-12-07 EP EP06841295A patent/EP1960418B1/en active Active
- 2006-12-07 PT PT06841295T patent/PT1960418E/pt unknown
- 2006-12-07 RU RU2008128465/04A patent/RU2400489C2/ru not_active IP Right Cessation
- 2006-12-07 CA CA2628798A patent/CA2628798C/en not_active Expired - Fee Related
- 2006-12-07 US US12/095,642 patent/US8268963B2/en active Active
- 2006-12-07 ES ES06841295T patent/ES2340804T3/es active Active
-
2008
- 2008-06-30 NO NO20082935A patent/NO20082935L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1960418B1 (en) | 2010-02-17 |
PL1960418T3 (pl) | 2010-07-30 |
US20100228005A1 (en) | 2010-09-09 |
RU2400489C2 (ru) | 2010-09-27 |
DE602006012360D1 (de) | 2010-04-01 |
JP2009519294A (ja) | 2009-05-14 |
AU2006326070B2 (en) | 2011-08-25 |
RU2008128465A (ru) | 2010-01-27 |
JP5124475B2 (ja) | 2013-01-23 |
EP1960418A1 (en) | 2008-08-27 |
DK1960418T3 (da) | 2010-05-31 |
WO2007068644A1 (en) | 2007-06-21 |
ATE457994T1 (de) | 2010-03-15 |
AU2006326070A1 (en) | 2007-06-21 |
EP1798237A1 (en) | 2007-06-20 |
CA2628798A1 (en) | 2007-06-21 |
PT1960418E (pt) | 2010-05-05 |
ES2340804T3 (es) | 2010-06-09 |
CA2628798C (en) | 2014-08-05 |
CN101341167A (zh) | 2009-01-07 |
US8268963B2 (en) | 2012-09-18 |
CN101341167B (zh) | 2012-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |