EA200970294A1 - Способ наращивания стволовых клеток взрослого организма из крови, в частности периферической, и соответственное применение в области медицины - Google Patents
Способ наращивания стволовых клеток взрослого организма из крови, в частности периферической, и соответственное применение в области медициныInfo
- Publication number
- EA200970294A1 EA200970294A1 EA200970294A EA200970294A EA200970294A1 EA 200970294 A1 EA200970294 A1 EA 200970294A1 EA 200970294 A EA200970294 A EA 200970294A EA 200970294 A EA200970294 A EA 200970294A EA 200970294 A1 EA200970294 A1 EA 200970294A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- stem cells
- blood
- correspondent
- medicine
- extension
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Cell Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
Abstract
Способ наращивания стволовых клеток взрослого организма из крови, в частности, но не только, периферической крови, состоящий из первого этапа наращивания стволовых клеток крови, сразу же после того, как они взяты, путем обработки клеток МКСФ в концентрации, составляющей 8-15 нМ, и второй этап очистки нарощенных стволовых клеток.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000498A ITRM20060498A1 (it) | 2006-09-20 | 2006-09-20 | Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico |
| PCT/EP2007/059531 WO2008034740A1 (en) | 2006-09-20 | 2007-09-11 | Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200970294A1 true EA200970294A1 (ru) | 2009-10-30 |
| EA019305B1 EA019305B1 (ru) | 2014-02-28 |
Family
ID=38126399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200970294A EA019305B1 (ru) | 2006-09-20 | 2007-09-11 | Способ получения плюрипотентных стволовых клеток взрослого организма из крови, в частности периферической, и применение полученных клеток в области медицины |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US8263400B2 (ru) |
| EP (1) | EP2076588B1 (ru) |
| JP (1) | JP5340941B2 (ru) |
| KR (1) | KR101570446B1 (ru) |
| CN (1) | CN101553565B (ru) |
| AU (1) | AU2007299043B2 (ru) |
| BR (1) | BRPI0715036A2 (ru) |
| CA (1) | CA2663072C (ru) |
| DK (1) | DK2076588T3 (ru) |
| EA (1) | EA019305B1 (ru) |
| ES (1) | ES2435080T3 (ru) |
| HK (1) | HK1138315A1 (ru) |
| HR (1) | HRP20131104T1 (ru) |
| IL (1) | IL197575A (ru) |
| IT (1) | ITRM20060498A1 (ru) |
| MX (1) | MX2009003059A (ru) |
| PL (1) | PL2076588T3 (ru) |
| RS (1) | RS53039B (ru) |
| SI (1) | SI2076588T1 (ru) |
| WO (1) | WO2008034740A1 (ru) |
| ZA (1) | ZA200901748B (ru) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9132116B2 (en) | 2004-08-02 | 2015-09-15 | Willowcroft Pharm Inc. | Mast cell stabilizers to prevent or treat laminitis |
| ITUD20080058A1 (it) * | 2008-03-18 | 2009-09-19 | Thankstem S R L | Kit per la raccolta di sangue, preferibilmente periferico, per la produzione di cellule staminali |
| EP2424527B8 (en) * | 2009-04-29 | 2019-07-17 | Willowcraft Pharm Inc. | Mast cell stabilizers to prevent or treat laminitis |
| KR101202836B1 (ko) * | 2010-08-27 | 2012-11-20 | 서울대학교산학협력단 | 세포응집을 이용한 인간 혈액 유래 혈구 세포괴의 유도와 이를 이용한 혈중 성체줄기세포 및 전구세포의 증폭방법 및 상기의 방법에 의해 제조된 줄기세포 |
| SG192254A1 (en) * | 2011-01-31 | 2013-08-30 | Royal Medical Group Pllc | Pluripotent stem cells and method of stimulating and extracting non-embryonic pluripotent stem cells from mammal blood and using reconstituted pluripotent stem cells to treat diseases including chronic obstructive pulmonary disease |
| BE1020480A5 (nl) * | 2012-10-01 | 2013-11-05 | Global Stem Cell Technology | Werkwijze voor de isolatie van mesenchymale stamcellen uit bloed van zoogdieren, en gebruik ervan. |
| DK3140396T3 (en) * | 2014-05-09 | 2018-11-12 | Thankstem S R L | Procedure for the expansion of adult stem cells from whole blood |
| RU2644650C2 (ru) | 2014-12-01 | 2018-02-13 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток и способ его получения |
| WO2016204230A1 (ja) * | 2015-06-17 | 2016-12-22 | 仁幸 小林 | 幹細胞投与方法、競走馬または競技馬の症状改善方法、注射用容器および幹細胞注射セット |
| RU2708329C2 (ru) | 2016-05-31 | 2019-12-05 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток, композиции и способы применения |
| CA3028422A1 (en) * | 2016-06-23 | 2017-12-28 | Tithon Biotech, Inc. | Cells expressing parathyroid hormone 1 receptor and uses thereof |
| US11103537B2 (en) | 2016-06-23 | 2021-08-31 | Tithon Biotech Inc. | Cells expressing parathyroid hormone 1 receptor and uses thereof |
| AU2020277774A1 (en) * | 2019-05-22 | 2021-12-09 | Thankstem S.R.L. | Method for expanding adult stem cells from whole blood |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1436843A (zh) * | 2002-02-08 | 2003-08-20 | 刘颉 | 脐血造血干细胞的制作方法 |
| TWI288779B (en) * | 2002-03-28 | 2007-10-21 | Blasticon Biotech Forschung | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
| CA2505394C (en) * | 2002-11-07 | 2014-05-13 | University Of Chicago | Human stem cell materials and methods |
| CN1667119A (zh) * | 2004-03-11 | 2005-09-14 | 中国人民解放军第二军医大学 | 一种成体干细胞及其培养方法和用途 |
-
2006
- 2006-09-20 IT IT000498A patent/ITRM20060498A1/it unknown
-
2007
- 2007-09-11 WO PCT/EP2007/059531 patent/WO2008034740A1/en active Application Filing
- 2007-09-11 SI SI200731352T patent/SI2076588T1/sl unknown
- 2007-09-11 CN CN200780034935.XA patent/CN101553565B/zh active Active
- 2007-09-11 RS RS20130499A patent/RS53039B/en unknown
- 2007-09-11 ES ES07820134T patent/ES2435080T3/es active Active
- 2007-09-11 JP JP2009528679A patent/JP5340941B2/ja active Active
- 2007-09-11 EP EP07820134.0A patent/EP2076588B1/en active Active
- 2007-09-11 PL PL07820134T patent/PL2076588T3/pl unknown
- 2007-09-11 MX MX2009003059A patent/MX2009003059A/es active IP Right Grant
- 2007-09-11 EA EA200970294A patent/EA019305B1/ru not_active IP Right Cessation
- 2007-09-11 CA CA2663072A patent/CA2663072C/en active Active
- 2007-09-11 DK DK07820134.0T patent/DK2076588T3/da active
- 2007-09-11 BR BRPI0715036-9A patent/BRPI0715036A2/pt not_active Application Discontinuation
- 2007-09-11 KR KR1020097007818A patent/KR101570446B1/ko active IP Right Grant
- 2007-09-11 AU AU2007299043A patent/AU2007299043B2/en not_active Ceased
-
2009
- 2009-03-11 ZA ZA200901748A patent/ZA200901748B/xx unknown
- 2009-03-12 IL IL197575A patent/IL197575A/en active IP Right Grant
- 2009-03-20 US US12/408,145 patent/US8263400B2/en active Active
-
2010
- 2010-04-07 HK HK10103425.7A patent/HK1138315A1/xx unknown
-
2012
- 2012-08-16 US US13/587,417 patent/US20120308535A1/en not_active Abandoned
-
2013
- 2013-11-19 HR HRP20131104TT patent/HRP20131104T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR101570446B1 (ko) | 2015-11-27 |
| CN101553565A (zh) | 2009-10-07 |
| IL197575A (en) | 2013-06-27 |
| CA2663072C (en) | 2016-01-19 |
| CA2663072A1 (en) | 2008-03-27 |
| AU2007299043A1 (en) | 2008-03-27 |
| MX2009003059A (es) | 2009-04-01 |
| HK1138315A1 (en) | 2010-08-20 |
| US8263400B2 (en) | 2012-09-11 |
| ZA200901748B (en) | 2010-03-31 |
| AU2007299043B2 (en) | 2013-06-27 |
| US20120308535A1 (en) | 2012-12-06 |
| IL197575A0 (en) | 2011-08-01 |
| EP2076588A1 (en) | 2009-07-08 |
| HRP20131104T1 (hr) | 2013-12-20 |
| KR20090074044A (ko) | 2009-07-03 |
| ITRM20060498A1 (it) | 2008-03-21 |
| RS53039B (en) | 2014-04-30 |
| ES2435080T3 (es) | 2013-12-18 |
| EA019305B1 (ru) | 2014-02-28 |
| SI2076588T1 (sl) | 2013-12-31 |
| DK2076588T3 (da) | 2013-11-11 |
| JP2010504083A (ja) | 2010-02-12 |
| PL2076588T3 (pl) | 2014-01-31 |
| US20100068189A1 (en) | 2010-03-18 |
| EP2076588B1 (en) | 2013-08-21 |
| CN101553565B (zh) | 2015-05-06 |
| BRPI0715036A2 (pt) | 2013-05-28 |
| JP5340941B2 (ja) | 2013-11-13 |
| WO2008034740A1 (en) | 2008-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |