ITRM20060498A1 - Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico - Google Patents

Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico

Info

Publication number
ITRM20060498A1
ITRM20060498A1 IT000498A ITRM20060498A ITRM20060498A1 IT RM20060498 A1 ITRM20060498 A1 IT RM20060498A1 IT 000498 A IT000498 A IT 000498A IT RM20060498 A ITRM20060498 A IT RM20060498A IT RM20060498 A1 ITRM20060498 A1 IT RM20060498A1
Authority
IT
Italy
Prior art keywords
expansion
stem cells
peripheral blood
medical field
adult stem
Prior art date
Application number
IT000498A
Other languages
English (en)
Inventor
Alessandra Gambacurta
Marco Polettini
Original Assignee
Alessandra Gambacurta
Marco Polettini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alessandra Gambacurta, Marco Polettini filed Critical Alessandra Gambacurta
Priority to IT000498A priority Critical patent/ITRM20060498A1/it
Priority to CN200780034935.XA priority patent/CN101553565B/zh
Priority to PCT/EP2007/059531 priority patent/WO2008034740A1/en
Priority to BRPI0715036-9A priority patent/BRPI0715036A2/pt
Priority to SI200731352T priority patent/SI2076588T1/sl
Priority to JP2009528679A priority patent/JP5340941B2/ja
Priority to AU2007299043A priority patent/AU2007299043B2/en
Priority to PL07820134T priority patent/PL2076588T3/pl
Priority to DK07820134.0T priority patent/DK2076588T3/da
Priority to RS20130499A priority patent/RS53039B/en
Priority to ES07820134T priority patent/ES2435080T3/es
Priority to MX2009003059A priority patent/MX2009003059A/es
Priority to EP07820134.0A priority patent/EP2076588B1/en
Priority to CA2663072A priority patent/CA2663072C/en
Priority to EA200970294A priority patent/EA019305B1/ru
Priority to KR1020097007818A priority patent/KR101570446B1/ko
Publication of ITRM20060498A1 publication Critical patent/ITRM20060498A1/it
Priority to ZA200901748A priority patent/ZA200901748B/xx
Priority to IL197575A priority patent/IL197575A/en
Priority to US12/408,145 priority patent/US8263400B2/en
Priority to HK10103425.7A priority patent/HK1138315A1/xx
Priority to US13/587,417 priority patent/US20120308535A1/en
Priority to HRP20131104TT priority patent/HRP20131104T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
IT000498A 2006-09-20 2006-09-20 Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico ITRM20060498A1 (it)

Priority Applications (22)

Application Number Priority Date Filing Date Title
IT000498A ITRM20060498A1 (it) 2006-09-20 2006-09-20 Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico
MX2009003059A MX2009003059A (es) 2006-09-20 2007-09-11 Metodo de expansion de celulas madre adultas procedentes de sangre, particularmente de sangre periferica, y la aplicacion correspondiente en el campo de la medicina.
EP07820134.0A EP2076588B1 (en) 2006-09-20 2007-09-11 Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field
PCT/EP2007/059531 WO2008034740A1 (en) 2006-09-20 2007-09-11 Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field
SI200731352T SI2076588T1 (sl) 2006-09-20 2007-09-11 Ekspanzijski postopek za odrasle izvorne celice iz krvi, zlasti periferne krvi, in s tem povezana uporaba na medicinskem področju
JP2009528679A JP5340941B2 (ja) 2006-09-20 2007-09-11 血液、特に末梢血から成体幹細胞を増殖させるための方法及び医療分野におけるその利用
AU2007299043A AU2007299043B2 (en) 2006-09-20 2007-09-11 Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field
PL07820134T PL2076588T3 (pl) 2006-09-20 2007-09-11 Sposób ekspansji dorosłych komórek macierzystych z krwi, szczególnie krwi obwodowej i odnośne zastosowanie w dziedzinie medycyny
DK07820134.0T DK2076588T3 (da) 2006-09-20 2007-09-11 Ekspansionsfremgangsmåde til voksne stamceller fra blod, især perifert blod, og dermed forbundet anvendelse på det medicinske område
CA2663072A CA2663072C (en) 2006-09-20 2007-09-11 Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field
ES07820134T ES2435080T3 (es) 2006-09-20 2007-09-11 Procedimiento de expansión de células madre adultas de sangre, en particular sangre periférica, y aplicación relativa en el campo médico
CN200780034935.XA CN101553565B (zh) 2006-09-20 2007-09-11 从血液特别是外周血扩增成体干细胞的方法及在医药领域的相关应用
BRPI0715036-9A BRPI0715036A2 (pt) 2006-09-20 2007-09-11 mÉtodo de expansço para cÉlulas-tronco adultas do sangue, particulamente sangue perifÉrico, e aplicaÇço relativa no campo mÉdico
RS20130499A RS53039B (en) 2006-09-20 2007-09-11 EXPANSION PROCEDURE FOR ADULT STEM BLOOD CELLS, ESPECIALLY PERIPHERAL BLOOD, AND APPROPRIATE MEDICAL APPLICATION
EA200970294A EA019305B1 (ru) 2006-09-20 2007-09-11 Способ получения плюрипотентных стволовых клеток взрослого организма из крови, в частности периферической, и применение полученных клеток в области медицины
KR1020097007818A KR101570446B1 (ko) 2006-09-20 2007-09-11 혈액 특히 말초 혈액으로부터 얻은 성체 줄기세포의 증대 방법 및 의학 분야의 관련 적용
ZA200901748A ZA200901748B (en) 2006-09-20 2009-03-11 Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field
IL197575A IL197575A (en) 2006-09-20 2009-03-12 A method for removing adult stem cells from the blood, using them to prepare drugs for the treatment of lesions, and a medical preparation containing these adult GES cells
US12/408,145 US8263400B2 (en) 2006-09-20 2009-03-20 Method for expanding adult stem cells from blood and compositions and methods for using the same
HK10103425.7A HK1138315A1 (en) 2006-09-20 2010-04-07 Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field
US13/587,417 US20120308535A1 (en) 2006-09-20 2012-08-16 Pharmaceutical Composition Containing Expanded Adult Stem Cells and Methods of Using Same for Treatment
HRP20131104TT HRP20131104T1 (hr) 2006-09-20 2013-11-19 Metoda širenja za odrasle matiäśne stanice iz krvi, posebno periferne krvi, te relativna uporaba u medicinskom podruäśju

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000498A ITRM20060498A1 (it) 2006-09-20 2006-09-20 Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico

Publications (1)

Publication Number Publication Date
ITRM20060498A1 true ITRM20060498A1 (it) 2008-03-21

Family

ID=38126399

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000498A ITRM20060498A1 (it) 2006-09-20 2006-09-20 Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico

Country Status (21)

Country Link
US (2) US8263400B2 (it)
EP (1) EP2076588B1 (it)
JP (1) JP5340941B2 (it)
KR (1) KR101570446B1 (it)
CN (1) CN101553565B (it)
AU (1) AU2007299043B2 (it)
BR (1) BRPI0715036A2 (it)
CA (1) CA2663072C (it)
DK (1) DK2076588T3 (it)
EA (1) EA019305B1 (it)
ES (1) ES2435080T3 (it)
HK (1) HK1138315A1 (it)
HR (1) HRP20131104T1 (it)
IL (1) IL197575A (it)
IT (1) ITRM20060498A1 (it)
MX (1) MX2009003059A (it)
PL (1) PL2076588T3 (it)
RS (1) RS53039B (it)
SI (1) SI2076588T1 (it)
WO (1) WO2008034740A1 (it)
ZA (1) ZA200901748B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9132116B2 (en) 2004-08-02 2015-09-15 Willowcroft Pharm Inc. Mast cell stabilizers to prevent or treat laminitis
ITUD20080058A1 (it) 2008-03-18 2009-09-19 Thankstem S R L Kit per la raccolta di sangue, preferibilmente periferico, per la produzione di cellule staminali
EP2424527B8 (en) * 2009-04-29 2019-07-17 Willowcraft Pharm Inc. Mast cell stabilizers to prevent or treat laminitis
KR101202836B1 (ko) * 2010-08-27 2012-11-20 서울대학교산학협력단 세포응집을 이용한 인간 혈액 유래 혈구 세포괴의 유도와 이를 이용한 혈중 성체줄기세포 및 전구세포의 증폭방법 및 상기의 방법에 의해 제조된 줄기세포
AU2012212254A1 (en) * 2011-01-31 2013-09-19 Royal Medical Group, Pllc Pluripotent stem cells and method of stimulating and extracting non-embryonic pluripotent stem cells from mammal blood and using reconstituted pluripotent stem cells to treat diseases including chronic obstructive pulmonary disease
BE1020480A5 (nl) 2012-10-01 2013-11-05 Global Stem Cell Technology Werkwijze voor de isolatie van mesenchymale stamcellen uit bloed van zoogdieren, en gebruik ervan.
RS57793B1 (sr) * 2014-05-09 2018-12-31 Thankstem S R L Postupak ekspandovanja odraslih matičnih ćelija iz cele krvi
RU2644650C2 (ru) 2014-12-01 2018-02-13 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток и способ его получения
WO2016204230A1 (ja) * 2015-06-17 2016-12-22 仁幸 小林 幹細胞投与方法、競走馬または競技馬の症状改善方法、注射用容器および幹細胞注射セット
RU2708329C2 (ru) 2016-05-31 2019-12-05 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток, композиции и способы применения
CA3028422A1 (en) * 2016-06-23 2017-12-28 Tithon Biotech, Inc. Cells expressing parathyroid hormone 1 receptor and uses thereof
US11103537B2 (en) 2016-06-23 2021-08-31 Tithon Biotech Inc. Cells expressing parathyroid hormone 1 receptor and uses thereof
CN113924361A (zh) * 2019-05-22 2022-01-11 善克思腾(股份)责任有限公司 从全血中扩增成体干细胞的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1436843A (zh) * 2002-02-08 2003-08-20 刘颉 脐血造血干细胞的制作方法
TWI288779B (en) * 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
EP2357223A3 (en) * 2002-11-07 2012-11-07 University Of Chicago Human stem cell material and methods
CN1667119A (zh) * 2004-03-11 2005-09-14 中国人民解放军第二军医大学 一种成体干细胞及其培养方法和用途

Also Published As

Publication number Publication date
WO2008034740A1 (en) 2008-03-27
JP5340941B2 (ja) 2013-11-13
EA200970294A1 (ru) 2009-10-30
MX2009003059A (es) 2009-04-01
EP2076588A1 (en) 2009-07-08
IL197575A0 (en) 2011-08-01
US8263400B2 (en) 2012-09-11
US20100068189A1 (en) 2010-03-18
EP2076588B1 (en) 2013-08-21
DK2076588T3 (da) 2013-11-11
KR20090074044A (ko) 2009-07-03
HK1138315A1 (en) 2010-08-20
CA2663072C (en) 2016-01-19
AU2007299043B2 (en) 2013-06-27
HRP20131104T1 (hr) 2013-12-20
ES2435080T3 (es) 2013-12-18
CN101553565A (zh) 2009-10-07
AU2007299043A1 (en) 2008-03-27
CN101553565B (zh) 2015-05-06
PL2076588T3 (pl) 2014-01-31
JP2010504083A (ja) 2010-02-12
ZA200901748B (en) 2010-03-31
EA019305B1 (ru) 2014-02-28
RS53039B (en) 2014-04-30
CA2663072A1 (en) 2008-03-27
KR101570446B1 (ko) 2015-11-27
BRPI0715036A2 (pt) 2013-05-28
SI2076588T1 (sl) 2013-12-31
US20120308535A1 (en) 2012-12-06
IL197575A (en) 2013-06-27

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