NO20082559L - Humane monoklonale antistoffer mot protein tyrosin kinase 7 (PTK7) og fremgangsmater for anvendelse av anti-PTK7 antistoffer - Google Patents
Humane monoklonale antistoffer mot protein tyrosin kinase 7 (PTK7) og fremgangsmater for anvendelse av anti-PTK7 antistofferInfo
- Publication number
- NO20082559L NO20082559L NO20082559A NO20082559A NO20082559L NO 20082559 L NO20082559 L NO 20082559L NO 20082559 A NO20082559 A NO 20082559A NO 20082559 A NO20082559 A NO 20082559A NO 20082559 L NO20082559 L NO 20082559L
- Authority
- NO
- Norway
- Prior art keywords
- ptk7
- antibodies
- methods
- monoclonal antibodies
- human monoclonal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Abstract
Foreliggende oppfinnelse tilveiebringer isolerte monoklonale antistoffer, spesielt humane monoklonale antistoffer, som binder spesifikt til PTK7 med høy affinitet. Nukleinsyremolekyler som koder for antistoffene ifølge oppfinnelsen, ekspresjonsvektorer, vertsceller og fremgangsmåter for ekspresjon av antistoffene ifølge oppfinnelsen er også fremskaffet. Immunkonjugater, bispesifikke molekyler og farmasøytiske sammensetninger omfattende antistoffene ifølge oppfinnelsen er også fremskaffet. Foreliggende oppfinnelse tilveiebringer også fremgangsmåter for deteksjon av PTK7, så vel som fremgangsmåter for behandling av ulike sykdommer, omfattende kreft og infeksjonssykdommer, ved anvendelse av anti-PTK7-antistoffer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74837305P | 2005-12-08 | 2005-12-08 | |
PCT/US2006/046837 WO2007067730A2 (en) | 2005-12-08 | 2006-12-08 | Human monoclonal antibodies to protein tyrosine kinase 7 ( ptk7 ) and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082559L true NO20082559L (no) | 2008-07-07 |
Family
ID=38123515
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082559A NO20082559L (no) | 2005-12-08 | 2008-06-02 | Humane monoklonale antistoffer mot protein tyrosin kinase 7 (PTK7) og fremgangsmater for anvendelse av anti-PTK7 antistoffer |
Country Status (22)
Country | Link |
---|---|
US (3) | US8222375B2 (no) |
EP (1) | EP1957539B1 (no) |
JP (1) | JP5401639B2 (no) |
KR (1) | KR101373464B1 (no) |
CN (1) | CN101360761B (no) |
AU (1) | AU2006321841C1 (no) |
BR (1) | BRPI0619582A2 (no) |
CA (1) | CA2632552C (no) |
DK (1) | DK1957539T3 (no) |
EA (1) | EA017812B1 (no) |
ES (1) | ES2406063T3 (no) |
HK (1) | HK1121174A1 (no) |
IL (1) | IL191788A (no) |
ME (1) | ME02002B (no) |
NO (1) | NO20082559L (no) |
NZ (2) | NZ569236A (no) |
PL (1) | PL1957539T3 (no) |
PT (1) | PT1957539E (no) |
RS (1) | RS52804B (no) |
SG (1) | SG177194A1 (no) |
SI (1) | SI1957539T1 (no) |
WO (1) | WO2007067730A2 (no) |
Families Citing this family (60)
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AU2008334076A1 (en) * | 2007-11-30 | 2009-06-11 | Bristol-Myers Squibb Company | Monoclonal antibody partner molecule conjugates directed to protein tyrosine kinase 7 (PTK7) |
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KR101123130B1 (ko) * | 2008-03-17 | 2012-03-30 | 연세대학교 산학협력단 | Ptk7 단백질의 기능 저해를 통한 세포의 이동, 침윤 또는 혈관신생 억제제 |
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2006
- 2006-12-08 DK DK06848508.5T patent/DK1957539T3/da active
- 2006-12-08 BR BRPI0619582-2A patent/BRPI0619582A2/pt not_active Application Discontinuation
- 2006-12-08 ES ES06848508T patent/ES2406063T3/es active Active
- 2006-12-08 KR KR1020087015763A patent/KR101373464B1/ko active IP Right Grant
- 2006-12-08 RS RS20130230A patent/RS52804B/en unknown
- 2006-12-08 NZ NZ569236A patent/NZ569236A/en not_active IP Right Cessation
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