BRPI0512496A - processos e composições para o tratamento de doenças policìsticas - Google Patents
processos e composições para o tratamento de doenças policìsticasInfo
- Publication number
- BRPI0512496A BRPI0512496A BRPI0512496-4A BRPI0512496A BRPI0512496A BR PI0512496 A BRPI0512496 A BR PI0512496A BR PI0512496 A BRPI0512496 A BR PI0512496A BR PI0512496 A BRPI0512496 A BR PI0512496A
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- processes
- gene
- treatment
- tissue
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 5
- 201000010099 disease Diseases 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 230000004071 biological effect Effects 0.000 abstract 2
- 230000037416 cystogenesis Effects 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 230000014509 gene expression Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 230000002596 correlated effect Effects 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 230000008467 tissue growth Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCESSOS E COMPOSIçõES PARA O TRATAMENTO DE DOENçAS POLICìSTICAS. A presente invenção refere-se a composições e processos para diagnóstico e tratamento de distúrbios policísticos através de inibição de atividade biológica de um gene agora correlacionado com aparecimento deste distúrbio. Somente por meio de ilustração, o gene Fator de Crescimento de Tecido-alfa (TGF-<244>) é um exemplo de um tal gene. Também são providas por esta invenção composições e processos para tratamento ou melhora de lesões císticas anormais e doenças associadas com a formação de cistos em tecido. Os processos e composições tratam e melhoram formação de cisto patolágica em tecido através de inibição ou aumento de expressão de gene ou a atividade biológica do produto de expressão de gene, ou seu receptor.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58267304P | 2004-06-23 | 2004-06-23 | |
| US58287504P | 2004-06-25 | 2004-06-25 | |
| PCT/US2005/021994 WO2006002203A2 (en) | 2004-06-23 | 2005-06-23 | Methods and compositions for the treatment of polycystic diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0512496A true BRPI0512496A (pt) | 2008-03-04 |
Family
ID=35782308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0512496-4A BRPI0512496A (pt) | 2004-06-23 | 2005-06-23 | processos e composições para o tratamento de doenças policìsticas |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070212352A1 (pt) |
| EP (1) | EP1781318A4 (pt) |
| JP (1) | JP2008504270A (pt) |
| BR (1) | BRPI0512496A (pt) |
| MX (1) | MXPA06014972A (pt) |
| WO (1) | WO2006002203A2 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101373464B1 (ko) | 2005-12-08 | 2014-03-14 | 메다렉스, 엘.엘.시. | 단백질 티로신 키나제 7(ｐｔｋ7)에 대한 인간 단일클론항체 및 그의 용도 |
| PL2662448T3 (pl) | 2007-05-11 | 2017-07-31 | Alexion Pharmaceuticals, Inc. | Kierowana do kości fosfataza alkaliczna, zestawy i sposoby jej zastosowania |
| MX2017007392A (es) | 2014-12-05 | 2019-01-24 | Alexion Pharma Inc | Tratamiento de convulsiones con fosfatasa alcalina recombinante. |
| CA3053239A1 (en) | 2017-02-17 | 2018-08-23 | George Todaro | Use of tgf alpha for the treatment of diseases and disorders |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2357110A1 (en) * | 2001-04-11 | 2002-10-11 | American Cyanamid Company | Method for the treatment of polycystic kidney disease |
-
2005
- 2005-06-23 WO PCT/US2005/021994 patent/WO2006002203A2/en active Application Filing
- 2005-06-23 EP EP05762475A patent/EP1781318A4/en not_active Withdrawn
- 2005-06-23 JP JP2007518218A patent/JP2008504270A/ja not_active Withdrawn
- 2005-06-23 BR BRPI0512496-4A patent/BRPI0512496A/pt not_active IP Right Cessation
- 2005-06-23 MX MXPA06014972A patent/MXPA06014972A/es unknown
-
2006
- 2006-12-21 US US11/643,077 patent/US20070212352A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006002203A8 (en) | 2008-12-18 |
| EP1781318A2 (en) | 2007-05-09 |
| MXPA06014972A (es) | 2007-03-07 |
| EP1781318A4 (en) | 2009-12-23 |
| WO2006002203A2 (en) | 2006-01-05 |
| JP2008504270A (ja) | 2008-02-14 |
| US20070212352A1 (en) | 2007-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |