NO20076634L - Erythropoietin reseptorpeptidformuleringer og anvendelser - Google Patents
Erythropoietin reseptorpeptidformuleringer og anvendelserInfo
- Publication number
- NO20076634L NO20076634L NO20076634A NO20076634A NO20076634L NO 20076634 L NO20076634 L NO 20076634L NO 20076634 A NO20076634 A NO 20076634A NO 20076634 A NO20076634 A NO 20076634A NO 20076634 L NO20076634 L NO 20076634L
- Authority
- NO
- Norway
- Prior art keywords
- erythropoietin receptor
- applications
- receptor peptide
- peptide formulations
- relates
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 108010075944 Erythropoietin Receptors Proteins 0.000 title abstract 3
- 102100036509 Erythropoietin receptor Human genes 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000000556 agonist Substances 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
- A61K47/665—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells the pre-targeting system, clearing therapy or rescue therapy involving biotin-(strept) avidin systems
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- A—HUMAN NECESSITIES
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- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Nanotechnology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Cell Biology (AREA)
- Medical Informatics (AREA)
- Endocrinology (AREA)
- Optics & Photonics (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68765505P | 2005-06-03 | 2005-06-03 | |
| PCT/US2006/021845 WO2006133144A2 (en) | 2005-06-03 | 2006-06-05 | Erythropoietin receptor peptide formulations and uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076634L true NO20076634L (no) | 2008-02-29 |
Family
ID=37499033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076634A NO20076634L (no) | 2005-06-03 | 2007-12-21 | Erythropoietin reseptorpeptidformuleringer og anvendelser |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7550433B2 (enExample) |
| EP (1) | EP1917023A4 (enExample) |
| JP (2) | JP2008542399A (enExample) |
| KR (2) | KR20120119921A (enExample) |
| CN (1) | CN101553242A (enExample) |
| AU (1) | AU2006255081B2 (enExample) |
| BR (1) | BRPI0613233A2 (enExample) |
| CA (1) | CA2609401A1 (enExample) |
| CR (1) | CR9570A (enExample) |
| EA (1) | EA014528B1 (enExample) |
| GE (1) | GEP20135981B (enExample) |
| IL (1) | IL187354A0 (enExample) |
| MA (1) | MA29557B1 (enExample) |
| MX (1) | MX2007015303A (enExample) |
| NO (1) | NO20076634L (enExample) |
| NZ (1) | NZ563433A (enExample) |
| SG (1) | SG162747A1 (enExample) |
| UA (1) | UA92497C2 (enExample) |
| WO (1) | WO2006133144A2 (enExample) |
| ZA (1) | ZA200711020B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7919461B2 (en) * | 2005-06-03 | 2011-04-05 | Affymax, Inc. | Erythropoietin receptor peptide formulations and uses |
| WO2009025957A1 (en) * | 2007-08-22 | 2009-02-26 | Takeda Pharmaceuticals Company Limited | Erythropoietin receptor peptide formulations and uses |
| US8324159B2 (en) * | 2005-06-03 | 2012-12-04 | Affymax, Inc. | Erythropoietin receptor peptide formulations and uses |
| US7550433B2 (en) * | 2005-06-03 | 2009-06-23 | Affymax, Inc. | Erythropoietin receptor peptide formulations and uses |
| CA2693383C (en) | 2006-10-27 | 2017-03-28 | Sunnybrook Health Sciences Center | Multimeric tie 2 agonists and uses thereof in stimulating angiogenesis |
| WO2008095004A2 (en) * | 2007-01-31 | 2008-08-07 | Affymax, Inc. | Nitrogen-based linkers for attaching modifying groups to polypeptides and other macromolecules |
| JP2009191056A (ja) * | 2008-02-15 | 2009-08-27 | Affymax Inc | 合成ペプチドをベースとするepoレセプターアゴニストを用いた抗エリスロポエチン抗体に媒介された障害の治療 |
| CN103044539B (zh) * | 2010-04-09 | 2014-10-22 | 苏州元基生物技术有限公司 | 重组促红细胞生成素及制备方法 |
| CN102838677B (zh) * | 2010-04-09 | 2014-10-22 | 苏州元基生物技术有限公司 | 重组促红细胞生成素及制备方法 |
| CN102210872A (zh) * | 2011-05-30 | 2011-10-12 | 深圳翰宇药业股份有限公司 | 一种聚乙二醇修饰肽药物制剂及其制备方法 |
| CN103450348B (zh) * | 2012-05-29 | 2016-03-30 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种促红细胞生成素模拟肽、其制备方法和用途 |
| CN104231067B (zh) * | 2013-06-07 | 2017-08-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 促红细胞生成素模拟肽化学二聚体及其用途 |
| CN105837681B (zh) * | 2015-01-13 | 2019-04-19 | 天津药物研究院 | 一种促红细胞生成素模拟肽衍生物、其制备方法和用途 |
| CN106317217B (zh) * | 2015-06-26 | 2019-06-28 | 天津药物研究院有限公司 | 一种促红细胞生成素模拟肽及其制备方法和应用 |
| CN106279398B (zh) * | 2015-06-26 | 2019-06-28 | 天津药物研究院有限公司 | 一种促红细胞生成素模拟肽及其制备方法和应用 |
| CN105085653B (zh) * | 2015-08-26 | 2019-01-08 | 天津药物研究院有限公司 | 一种促红细胞生成素模拟肽及其制备方法和应用 |
| CN105085654B (zh) * | 2015-08-26 | 2019-01-08 | 天津药物研究院有限公司 | 一种促红细胞生成素模拟肽及其制备方法和应用 |
| CN105153293B (zh) * | 2015-08-26 | 2019-01-08 | 天津药物研究院有限公司 | 一种促红细胞生成素模拟肽及其二聚体、以及制备方法和应用 |
| CN105418754A (zh) * | 2015-09-30 | 2016-03-23 | 天津药物研究院有限公司 | 羟乙基淀粉修饰的促红细胞生成素模拟肽及其制备和应用 |
| CN106608911B (zh) * | 2015-10-22 | 2020-01-07 | 天津药物研究院有限公司 | 一种二硫键修饰的epo拟肽衍生物及其制备方法和应用 |
| CN106608913B (zh) * | 2015-10-22 | 2020-05-05 | 天津药物研究院有限公司 | 一种1,2,3-丙三酸偶联的epo拟肽衍生物及其制备方法和应用 |
| CN106608912B (zh) * | 2015-10-22 | 2019-09-20 | 天津药物研究院有限公司 | 一种脂肪二羧酸偶联的epo模拟肽衍生物及其制备方法和应用 |
| CN105367629B (zh) * | 2015-11-09 | 2019-01-08 | 天津药物研究院有限公司 | 一种促红细胞生成素模拟肽以及其制备方法和用途 |
| CN116077741A (zh) * | 2022-08-24 | 2023-05-09 | 深圳先进技术研究院 | 一种可固定细胞并在体内实现细胞增殖和释放的微米级3d细胞生物支架及其应用 |
Family Cites Families (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4703008A (en) | 1983-12-13 | 1987-10-27 | Kiren-Amgen, Inc. | DNA sequences encoding erythropoietin |
| KR850004274A (ko) * | 1983-12-13 | 1985-07-11 | 원본미기재 | 에리트로포이에틴의 제조방법 |
| NZ210501A (en) * | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
| US4677195A (en) * | 1985-01-11 | 1987-06-30 | Genetics Institute, Inc. | Method for the purification of erythropoietin and erythropoietin compositions |
| CH671155A5 (enExample) | 1986-08-18 | 1989-08-15 | Clinical Technologies Ass | |
| US5006333A (en) * | 1987-08-03 | 1991-04-09 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
| US5080891A (en) * | 1987-08-03 | 1992-01-14 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
| WO1990008822A1 (en) * | 1989-02-03 | 1990-08-09 | Genetics Institute, Inc. | Erythropoietin receptor |
| US5166322A (en) | 1989-04-21 | 1992-11-24 | Genetics Institute | Cysteine added variants of interleukin-3 and chemical modifications thereof |
| ES2085297T3 (es) | 1989-05-27 | 1996-06-01 | Sumitomo Pharma | Procedimiento para preparar derivados de poli(etilenglicol) y proteina modificada. |
| US5424186A (en) | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5723286A (en) | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
| US5292654A (en) * | 1990-12-13 | 1994-03-08 | Whitehead Institute For Biomedical Research | Mutant EPO receptor and uses therefor |
| NZ241954A (en) | 1991-03-15 | 1994-01-26 | Amgen Inc | Compositions of g-csf for pulmonary administration. |
| JP3693671B2 (ja) | 1991-03-15 | 2005-09-07 | アムゲン インコーポレーテッド | ポリペプチドのpeg化 |
| JPH06506217A (ja) | 1991-03-18 | 1994-07-14 | エンゾン,インコーポレーテッド | ポリペプチドまたはグリコポリペプチドとポリマーとのヒドラジン含有結合体 |
| CA2118806A1 (en) | 1991-09-18 | 1993-04-01 | William J. Dower | Method of synthesizing diverse collections of oligomers |
| US5614184A (en) * | 1992-07-28 | 1997-03-25 | New England Deaconess Hospital | Recombinant human erythropoietin mutants and therapeutic methods employing them |
| US6153407A (en) * | 1992-07-28 | 2000-11-28 | Beth Israel Deaconess Medical Center | Erythropoietin DNA having modified 5' and 3' sequences and its use to prepare EPO therapeutics |
| US5888511A (en) * | 1993-02-26 | 1999-03-30 | Advanced Biotherapy Concepts, Inc. | Treatment of autoimmune diseases, including AIDS |
| US5919455A (en) * | 1993-10-27 | 1999-07-06 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
| US5773569A (en) * | 1993-11-19 | 1998-06-30 | Affymax Technologies N.V. | Compounds and peptides that bind to the erythropoietin receptor |
| US5830851A (en) * | 1993-11-19 | 1998-11-03 | Affymax Technologies N.V. | Methods of administering peptides that bind to the erythropoietin receptor |
| US5747446A (en) * | 1994-03-22 | 1998-05-05 | Beth Israel Deaconess Medical Center | Modified polypeptides with increased biological activity |
| US5919758A (en) * | 1994-03-22 | 1999-07-06 | Beth Israel Deaconess Medical Center | Modified polypeptides with altered biological activity |
| US5580853A (en) * | 1994-03-22 | 1996-12-03 | New England Deaconess Hospital | Modified polypeptides with increased biological activity |
| US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
| US5767078A (en) * | 1995-06-07 | 1998-06-16 | Johnson; Dana L. | Agonist peptide dimers |
| EP1510524A3 (en) | 1995-06-07 | 2006-06-07 | Ortho Pharmaceutical Corporation | Compounds and peptides that bind to the erythropoietin receptor |
| YU34196A (sh) | 1995-06-07 | 1999-03-04 | Glaxo Group Limited | Peptidi i jedinjenja koja se vezuju za receptor |
| US5668110A (en) * | 1995-06-07 | 1997-09-16 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-5 receptor |
| US5683983A (en) * | 1995-06-07 | 1997-11-04 | Glaxo Group Limited | Peptides and compounds that bind to the IL-5 receptor |
| US5869451A (en) * | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| US5677280A (en) * | 1995-06-07 | 1997-10-14 | Glaxo Group Limited | Peptides and compounds that bind to the IL-5 receptor |
| US5654276A (en) * | 1995-06-07 | 1997-08-05 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-5 receptor |
| US6251864B1 (en) * | 1995-06-07 | 2001-06-26 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| AR003431A1 (es) * | 1995-06-07 | 1998-08-05 | Glaxo Group Ltd | Peptidos compuestos que se ligan al receptor de trombopoietina. |
| US5672662A (en) * | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| US6346390B1 (en) | 1996-03-08 | 2002-02-12 | Receptron, Inc. | Receptor derived peptides involved in modulation of response to ligand binding |
| US6103879A (en) * | 1996-06-21 | 2000-08-15 | Axys Pharmaceuticals, Inc. | Bivalent molecules that form an activating complex with an erythropoietin receptor |
| JP4410852B2 (ja) * | 1996-08-02 | 2010-02-03 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 単一の共有結合n末端水溶性ポリマーを有するポリペプチド |
| US5932546A (en) * | 1996-10-04 | 1999-08-03 | Glaxo Wellcome Inc. | Peptides and compounds that bind to the thrombopoietin receptor |
| CA2268742A1 (en) * | 1996-10-25 | 1998-04-30 | G.D. Searle & Co. | Multi-functional chimeric hematopoietic receptor agonists |
| US6221608B1 (en) * | 1997-01-22 | 2001-04-24 | Ortho Pharmaceutical Corporation | Methods for identifying erythropoietin receptor binding protein |
| JP4304757B2 (ja) | 1998-04-24 | 2009-07-29 | 株式会社デンソー | Absアクチュエータ |
| PT2158923E (pt) * | 1998-08-06 | 2013-06-04 | Univ Duke | Conjugados de peg-urato oxidase e sua utilização |
| JP5183836B2 (ja) | 1998-08-06 | 2013-04-17 | マウンテン ビュー ファーマシューティカルズ,インコーポレイテッド | Peg−尿酸酸化酵素結合体およびその使用 |
| US6783965B1 (en) * | 2000-02-10 | 2004-08-31 | Mountain View Pharmaceuticals, Inc. | Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates |
| EP1008355A1 (en) | 1998-12-08 | 2000-06-14 | Debio Recherche Pharmaceutique S.A. | Method for identifying or analyzing polymer linkage sites on macromolecules using amino acid report binding |
| EP1107998B1 (en) | 1998-08-28 | 2004-02-04 | Gryphon Sciences | Method for the preparation of polyamide chains of precise length, their conjugates with proteins |
| PL219605B1 (pl) | 1998-10-23 | 2015-06-30 | Kirin Amgen Inc | Dimeryczne mimetyki peptydów trombopoetynowych wiążące się z receptorem MP1 i wykazujące aktywność trombopoetyczną |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| EP1133291B1 (en) * | 1998-11-17 | 2006-01-11 | Smithkline Beecham Corporation | Cyclic polyamines for treating thrombocytopenia |
| CZ299516B6 (cs) * | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem |
| JO2291B1 (en) * | 1999-07-02 | 2005-09-12 | اف . هوفمان لاروش ايه جي | Erythropoietin derivatives |
| AUPQ873300A0 (en) * | 2000-07-12 | 2000-08-03 | Medvet Science Pty. Ltd. | A binding motif of a receptor (2) |
| WO2001021180A1 (en) * | 1999-09-24 | 2001-03-29 | Smithkline Beecham Corporation | Thrombopoietin mimetics |
| DE60025241T2 (de) * | 1999-09-27 | 2007-01-11 | Chugai Seiyaku K.K. | HäMOPOIETINREZEPTOR-PROTEIN, NR12 |
| US6703480B1 (en) | 1999-11-24 | 2004-03-09 | Palani Balu | Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use |
| US6858630B2 (en) * | 1999-12-06 | 2005-02-22 | Smithkline Beecham Corporation | Naphthimidazole derivatives and their use as thrombopoietin mimetics |
| JP2004512258A (ja) * | 2000-03-21 | 2004-04-22 | ウィスコンシン アルムニ リサーチ ファンデイション | 生物系における細胞応答の調節のための方法および試薬 |
| US6777387B2 (en) * | 2000-03-31 | 2004-08-17 | Enzon Pharmaceuticals, Inc. | Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same |
| KR20050121762A (ko) * | 2000-05-15 | 2005-12-27 | 에프. 호프만-라 로슈 아게 | 신규한 약학 조성물 |
| JP2003534384A (ja) | 2000-05-26 | 2003-11-18 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 神経保護性ペプチド |
| MXPA03001039A (es) * | 2000-08-02 | 2004-09-10 | Johnson & Johnson | Quimioterapia anti-viral y anti-tumor mejorada mediante administracion de eritropoeitina. |
| WO2002020033A1 (en) * | 2000-09-08 | 2002-03-14 | Gryphon Therapeutics, Inc. | Polymer-modified synthetic proteins |
| JP4656814B2 (ja) * | 2000-12-20 | 2011-03-23 | エフ.ホフマン−ラ ロシュ アーゲー | エリスロポエチンコンジュゲート |
| US7767643B2 (en) * | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| US6531121B2 (en) * | 2000-12-29 | 2003-03-11 | The Kenneth S. Warren Institute, Inc. | Protection and enhancement of erythropoietin-responsive cells, tissues and organs |
| WO2002065988A2 (en) | 2001-02-20 | 2002-08-29 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
| FR2823220B1 (fr) * | 2001-04-04 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo) |
| US20020169128A1 (en) * | 2001-04-09 | 2002-11-14 | Geroge Sigounas | Erythropoietin ameliorates chemotherapy-induced toxicity in vivo |
| ATE414711T1 (de) | 2001-06-28 | 2008-12-15 | Mountain View Pharmaceuticals | Polymerstabilisierte proteinasen |
| US6784154B2 (en) * | 2001-11-01 | 2004-08-31 | University Of Utah Research Foundation | Method of use of erythropoietin to treat ischemic acute renal failure |
| US7087229B2 (en) | 2003-05-30 | 2006-08-08 | Enzon Pharmaceuticals, Inc. | Releasable polymeric conjugates based on aliphatic biodegradable linkers |
| US7122189B2 (en) | 2002-08-13 | 2006-10-17 | Enzon, Inc. | Releasable polymeric conjugates based on aliphatic biodegradable linkers |
| US20050176627A1 (en) * | 2002-09-09 | 2005-08-11 | Anthony Cerami | Long acting erythropoietins that maintain tissue protective activity of endogenous erythropoietin |
| US8129330B2 (en) * | 2002-09-30 | 2012-03-06 | Mountain View Pharmaceuticals, Inc. | Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof |
| US20040062748A1 (en) | 2002-09-30 | 2004-04-01 | Mountain View Pharmaceuticals, Inc. | Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof |
| US7396913B2 (en) * | 2002-10-14 | 2008-07-08 | Abbott Laboratories | Erythropoietin receptor binding antibodies |
| CA2504878A1 (en) * | 2002-11-06 | 2004-05-27 | Schering Corporation | Cholesterol absorption inhibitors for the treatment of demyelination |
| JP5207590B2 (ja) * | 2002-12-26 | 2013-06-12 | マウンテン ビュー ファーマシューティカルズ,インコーポレイテッド | 増強された生物学的能力を有するインターフェロン−βのポリマー結合体 |
| US20040136952A1 (en) * | 2002-12-26 | 2004-07-15 | Mountain View Pharmaceuticals, Inc. | Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity |
| CA2525399A1 (en) | 2003-05-12 | 2004-11-25 | Affymax, Inc. | Novel spacer moiety for poly(ethylene glycol)-modified peptide-based co mpounds |
| EA010099B1 (ru) | 2003-05-12 | 2008-06-30 | Афимакс, Инк. | Пептиды, которые связываются с рецептором к эритропоэтину, и способы их применения |
| CA2525464A1 (en) | 2003-05-12 | 2004-11-25 | Qun Yin | Novel poly(ethylene glycol) modified compounds and uses thereof |
| SG160224A1 (en) | 2003-05-12 | 2010-04-29 | Affymax Inc | Novel peptides that bind to the erythropoietin receptor |
| US7550433B2 (en) * | 2005-06-03 | 2009-06-23 | Affymax, Inc. | Erythropoietin receptor peptide formulations and uses |
-
2006
- 2006-06-02 US US11/446,593 patent/US7550433B2/en not_active Expired - Fee Related
- 2006-06-05 KR KR1020127022673A patent/KR20120119921A/ko not_active Ceased
- 2006-06-05 WO PCT/US2006/021845 patent/WO2006133144A2/en not_active Ceased
- 2006-06-05 UA UAA200714845A patent/UA92497C2/ru unknown
- 2006-06-05 GE GEAP200610461A patent/GEP20135981B/en unknown
- 2006-06-05 BR BRPI0613233-2A patent/BRPI0613233A2/pt not_active IP Right Cessation
- 2006-06-05 NZ NZ563433A patent/NZ563433A/en not_active IP Right Cessation
- 2006-06-05 SG SG201003903-0A patent/SG162747A1/en unknown
- 2006-06-05 US US11/916,416 patent/US7906485B2/en not_active Expired - Fee Related
- 2006-06-05 CA CA002609401A patent/CA2609401A1/en not_active Abandoned
- 2006-06-05 EP EP06784593A patent/EP1917023A4/en not_active Withdrawn
- 2006-06-05 EA EA200702656A patent/EA014528B1/ru not_active IP Right Cessation
- 2006-06-05 AU AU2006255081A patent/AU2006255081B2/en not_active Ceased
- 2006-06-05 CN CNA2006800269914A patent/CN101553242A/zh active Pending
- 2006-06-05 MX MX2007015303A patent/MX2007015303A/es active IP Right Grant
- 2006-06-05 JP JP2008514966A patent/JP2008542399A/ja active Pending
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- 2007-11-13 IL IL187354A patent/IL187354A0/en unknown
- 2007-12-06 CR CR9570A patent/CR9570A/es not_active Application Discontinuation
- 2007-12-19 ZA ZA200711020A patent/ZA200711020B/xx unknown
- 2007-12-21 NO NO20076634A patent/NO20076634L/no not_active Application Discontinuation
- 2007-12-24 MA MA30497A patent/MA29557B1/fr unknown
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2008
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Also Published As
| Publication number | Publication date |
|---|---|
| EA014528B1 (ru) | 2010-12-30 |
| AU2006255081A1 (en) | 2006-12-14 |
| NZ563433A (en) | 2009-12-24 |
| US20070104704A1 (en) | 2007-05-10 |
| US20090136442A1 (en) | 2009-05-28 |
| US7550433B2 (en) | 2009-06-23 |
| KR20120119921A (ko) | 2012-10-31 |
| CR9570A (es) | 2008-05-05 |
| WO2006133144A2 (en) | 2006-12-14 |
| AU2006255081B2 (en) | 2012-03-29 |
| MX2007015303A (es) | 2008-03-05 |
| IL187354A0 (en) | 2008-04-13 |
| JP2013173763A (ja) | 2013-09-05 |
| KR101262312B1 (ko) | 2013-05-14 |
| MA29557B1 (fr) | 2008-06-02 |
| SG162747A1 (en) | 2010-07-29 |
| EP1917023A2 (en) | 2008-05-07 |
| ZA200711020B (en) | 2008-12-31 |
| BRPI0613233A2 (pt) | 2010-12-28 |
| EP1917023A4 (en) | 2010-03-24 |
| JP2008542399A (ja) | 2008-11-27 |
| CN101553242A (zh) | 2009-10-07 |
| US7906485B2 (en) | 2011-03-15 |
| GEP20135981B (en) | 2013-12-10 |
| WO2006133144A8 (en) | 2008-04-17 |
| UA92497C2 (ru) | 2010-11-10 |
| CA2609401A1 (en) | 2006-12-14 |
| EA200702656A1 (ru) | 2008-12-30 |
| KR20080021115A (ko) | 2008-03-06 |
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