NO20076460L - Nye fluorenderivater, sammensetninger inneholdende nevnte derivater og anvendelse derav - Google Patents

Nye fluorenderivater, sammensetninger inneholdende nevnte derivater og anvendelse derav

Info

Publication number
NO20076460L
NO20076460L NO20076460A NO20076460A NO20076460L NO 20076460 L NO20076460 L NO 20076460L NO 20076460 A NO20076460 A NO 20076460A NO 20076460 A NO20076460 A NO 20076460A NO 20076460 L NO20076460 L NO 20076460L
Authority
NO
Norway
Prior art keywords
derivatives
compositions containing
new fluorine
new
tautomers
Prior art date
Application number
NO20076460A
Other languages
English (en)
Norwegian (no)
Inventor
Patrick Mailliet
Jean-Marie Ruxer
Chantal Carrez
Didier Benard
Luc Bertin
Fabienne Thompson
Thierry Guyon
Fabienne Pilorge
Herve Minoux
Helene Goulaouic
Original Assignee
Avantis Pharma S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avantis Pharma S A filed Critical Avantis Pharma S A
Publication of NO20076460L publication Critical patent/NO20076460L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
NO20076460A 2005-05-19 2007-12-14 Nye fluorenderivater, sammensetninger inneholdende nevnte derivater og anvendelse derav NO20076460L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0505037A FR2885904B1 (fr) 2005-05-19 2005-05-19 Nouveaux derives du fluorene, compositions les contenant et utilisation
PCT/FR2006/001137 WO2006123061A2 (fr) 2005-05-19 2006-05-19 Derives du fluorene, compositions les contenant et utilisation

Publications (1)

Publication Number Publication Date
NO20076460L true NO20076460L (no) 2008-02-19

Family

ID=36036699

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076460A NO20076460L (no) 2005-05-19 2007-12-14 Nye fluorenderivater, sammensetninger inneholdende nevnte derivater og anvendelse derav

Country Status (31)

Country Link
US (1) US7674795B2 (zh)
EP (1) EP1888579B1 (zh)
JP (1) JP4964874B2 (zh)
KR (1) KR101288696B1 (zh)
CN (1) CN101203518B (zh)
AR (1) AR054125A1 (zh)
AT (1) ATE518859T1 (zh)
AU (1) AU2006248825B2 (zh)
BR (1) BRPI0611424A2 (zh)
CA (1) CA2608378C (zh)
CR (1) CR9515A (zh)
DO (1) DOP2006000112A (zh)
EA (1) EA019027B1 (zh)
FR (1) FR2885904B1 (zh)
GT (1) GT200600206A (zh)
HN (1) HN2006018410A (zh)
IL (1) IL187163A (zh)
JO (1) JO2753B1 (zh)
MA (1) MA29493B1 (zh)
MX (1) MX2007014443A (zh)
MY (1) MY149037A (zh)
NO (1) NO20076460L (zh)
NZ (1) NZ563239A (zh)
PA (1) PA8675701A1 (zh)
PE (1) PE20061367A1 (zh)
TN (1) TNSN07389A1 (zh)
TW (1) TWI386406B (zh)
UA (1) UA93203C2 (zh)
UY (1) UY29549A1 (zh)
WO (1) WO2006123061A2 (zh)
ZA (1) ZA200709856B (zh)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8779144B2 (en) 2006-03-16 2014-07-15 Evotec (Us) Inc. Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
FR2907453B1 (fr) * 2006-10-24 2008-12-26 Sanofi Aventis Sa Nouveaux derives du fluorene,compositions les contenant et utilisation
US8759819B2 (en) * 2007-11-22 2014-06-24 Idemitsu Kosan Co., Ltd. Organic electroluminescence device
EP2276733A2 (en) * 2008-03-31 2011-01-26 Council Of Scientific & Industrial Research Novel donor-acceptor fluorene scaffolds: a process and uses thereof
GB0809314D0 (en) * 2008-05-22 2008-07-02 Summit Corp Plc Compounds for treating muscular dystrophy
CA2763536C (en) 2008-05-30 2017-05-09 Marvin J. Miller Anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria
FR2932484B1 (fr) 2008-06-16 2010-06-18 Sanofi Aventis Nouveaux derives de pyrroloindole inhibiteurs d'hsp90, compositions les contenant et utilisation
BRPI0913673A2 (pt) * 2008-07-02 2015-10-13 British Columbia Cancer Agency uso de um composto, composição farmacêutica, e, método para modular a atividade do receptor de andrógeno
AR074797A1 (es) 2008-10-10 2011-02-16 Japan Tobacco Inc Compuesto de fluoreno , composiciones farmaceuticas , inhibidores de pdhk y pdhk2 , metodos de tratamiento , usos de los mismos y kit comercial
AR077405A1 (es) 2009-07-10 2011-08-24 Sanofi Aventis Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer
FR2949467B1 (fr) 2009-09-03 2011-11-25 Sanofi Aventis Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation
EP2521707B1 (en) 2010-01-06 2017-06-14 British Columbia Cancer Agency Branch Bisphenol derivatives and their use as androgen receptor activity modulators
US9290485B2 (en) 2010-08-04 2016-03-22 Novartis Ag N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides
WO2012145330A1 (en) * 2011-04-18 2012-10-26 The University Of British Columbia Fluorene-9-bisphenol compounds and methods for their use
CN102442973A (zh) * 2011-09-22 2012-05-09 华东理工大学 催化氧化伯醇闭环合成苯并咪唑和苯并噻唑化合物的方法
CN104093689A (zh) * 2012-01-31 2014-10-08 剑桥显示技术有限公司 聚合物
US9365510B2 (en) 2012-04-16 2016-06-14 British Columbia Cancer Agency Branch Aziridine bisphenol ethers and related compounds and methods for their use
NZ702169A (en) 2012-05-25 2016-10-28 Berg Llc The use of heat shock protein 90 (hsp90) modulators for the treatment of metabolic syndrome
CA2904985C (en) 2013-03-15 2021-07-20 Japan Tobacco Inc. Pyrazole-amide compound and medicinal uses therefor
CN105358522A (zh) 2013-05-10 2016-02-24 不列颠哥伦比亚癌症局分支机构 雄激素受体调节剂的酯衍生物及其使用方法
GB201311891D0 (en) 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compound
GB201311888D0 (en) 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compounds
US9375496B2 (en) 2013-09-09 2016-06-28 British Columbia Cancer Agency Branch Halogenated compounds for cancer imaging and treatment and methods for their use
KR102280686B1 (ko) 2014-02-11 2021-07-22 삼성전자주식회사 카바졸계 화합물 및 이를 포함한 유기 발광 소자
CN106458993A (zh) * 2014-04-14 2017-02-22 阿尔维纳斯股份有限公司 基于酰亚胺的蛋白水解调节剂和相关使用方法
AU2015269054A1 (en) 2014-06-06 2017-01-12 Berg Llc Methods of treating a metabolic syndrome by modulating heat shock protein (HSP) 90-beta
US11351155B2 (en) 2014-12-05 2022-06-07 Case Western Reserve University Compositions and methods of modulating s-nitrosylation
US11426386B2 (en) 2014-12-05 2022-08-30 Case Western Reserve University Compositions and methods of modulating S-nitrosylation
ES2907708T3 (es) 2015-01-13 2022-04-26 British Columbia Cancer Agency Branch Compuestos heterocíclicos para obtención de imágenes y tratamiento del cáncer y métodos para su uso
WO2016141458A1 (en) 2015-03-12 2016-09-15 British Columbia Cancer Agency Branch Bisphenol ether derivatives and methods for using the same
WO2016197032A1 (en) * 2015-06-04 2016-12-08 Arvinas, Inc. Imide-based modulators of proteolysis and associated methods of use
US20170298033A1 (en) 2016-04-15 2017-10-19 The University Of British Columbia Bisphenol derivatives and their use as androgen receptor activity modulators
CN114716377A (zh) 2016-07-29 2022-07-08 日本烟草产业株式会社 吡唑-酰胺化合物的制造方法
CN111356764B (zh) 2017-09-25 2024-05-24 卡斯西部储备大学 降低血清胆固醇和pcsk9的组合物和方法
US11485713B2 (en) 2018-05-25 2022-11-01 Essa Pharma, Inc. Androgen receptor modulators and methods for their use
US11931339B2 (en) 2018-06-25 2024-03-19 Case Western Reserve University Compositions and methods for treating tissue injury
JP2022502368A (ja) * 2018-09-21 2022-01-11 ケース ウエスタン リザーブ ユニバーシティ アルドケトレダクターゼ阻害剤およびその使用
KR20210093886A (ko) 2018-10-18 2021-07-28 에싸 파마 아이엔씨. 안드로겐 수용체 조절제 및 그 사용 방법
CN109574917B (zh) * 2018-12-03 2020-12-08 武汉尚赛光电科技有限公司 一种芴酮衍生物及其制备和应用
US11174263B2 (en) 2018-12-31 2021-11-16 Biomea Fusion, Inc. Inhibitors of menin-MLL interaction
CA3125350A1 (en) 2018-12-31 2020-07-09 Biomea Fusion, Llc Irreversible inhibitors of menin-mll interaction
CN110981795B (zh) * 2019-12-18 2021-02-12 武汉世纪久海检测技术有限公司 一种利用2-氰基异烟酸甲酯制备2-氨酰基异烟酸的方法
EP4135675A4 (en) 2020-04-17 2024-04-10 Essa Pharma, Inc. SOLID FORMS OF AN N-TERMINAL DOMAIN ANDROGEN RECEPTOR INHIBITOR AND USES THEREOF

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6015796A (en) * 1995-06-14 1997-01-15 Yamanouchi Pharmaceutical Co., Ltd. Fused imidazole derivatives and medicinal composition thereof
PL213103B1 (pl) * 2000-08-14 2013-01-31 Ortho Mcneil Pharm Inc Podstawiona pochodna pirazolu, jej zastosowanie i zawierajaca ja kompozycja farmaceutyczna
JP4399265B2 (ja) * 2001-12-21 2010-01-13 ヴァーナリス(ケンブリッジ)リミテッド 3,4−ジアリールピラゾール、および癌の治療におけるそれらの使用
GB0228417D0 (en) 2002-12-05 2003-01-08 Cancer Rec Tech Ltd Pyrazole compounds
GB0229618D0 (en) 2002-12-19 2003-01-22 Cancer Rec Tech Ltd Pyrazole compounds
JP2006511583A (ja) * 2002-12-20 2006-04-06 ファルマシア・コーポレーション マイトジェン活性化プロテインキナーゼ−活性化プロテインキナーゼ−2を阻害するための非環式ピラゾール化合物
WO2004072081A1 (en) * 2003-02-10 2004-08-26 Cellular Genomics, Inc. Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of kinase activity
EA009919B1 (ru) 2003-02-11 2008-04-28 Вернэлис (Кембридж) Лимитед Соединения изоксазола
GB0309637D0 (en) 2003-04-28 2003-06-04 Cancer Rec Tech Ltd Pyrazole compounds
CN100567242C (zh) 2003-06-27 2009-12-09 协和发酵麒麟株式会社 Hsp90家族蛋白质阻断剂
GB0315111D0 (en) 2003-06-27 2003-07-30 Cancer Rec Tech Ltd Substituted 5-membered ring compounds and their use
KR101139314B1 (ko) 2003-08-29 2012-04-26 베르날리스(캠브리지)리미티드 피리미도티오펜 화합물
GB0323810D0 (en) * 2003-10-10 2003-11-12 Cancer Rec Tech Ltd Pyridothiophene compounds
EP1704856A4 (en) * 2003-12-26 2009-08-19 Kyowa Hakko Kirin Co Ltd PROTEIN INHIBITOR OF THE HSP90 FAMILY
FR2884252B1 (fr) * 2005-04-08 2007-05-18 Aventis Pharma Sa Nouveaux derives d'isoindoles, compositions les contenant, leur preparation et leurs utilisations pharmaceutiques notamment en tant qu'inhibiteurs d'activites de la proteine chaperone hsp90

Also Published As

Publication number Publication date
KR101288696B1 (ko) 2013-07-22
ATE518859T1 (de) 2011-08-15
CN101203518A (zh) 2008-06-18
ZA200709856B (en) 2009-12-30
EA019027B1 (ru) 2013-12-30
US7674795B2 (en) 2010-03-09
EP1888579A2 (fr) 2008-02-20
US20080153837A1 (en) 2008-06-26
PA8675701A1 (es) 2006-12-07
HN2006018410A (es) 2010-03-05
EP1888579B1 (fr) 2011-08-03
MX2007014443A (es) 2008-02-11
WO2006123061A3 (fr) 2007-01-11
WO2006123061A2 (fr) 2006-11-23
GT200600206A (es) 2006-12-26
TWI386406B (zh) 2013-02-21
CA2608378C (fr) 2013-12-31
MY149037A (en) 2013-07-15
IL187163A0 (en) 2008-02-09
UY29549A1 (es) 2006-12-29
DOP2006000112A (es) 2007-01-31
TNSN07389A1 (en) 2009-03-17
MA29493B1 (fr) 2008-05-02
JP4964874B2 (ja) 2012-07-04
JP2008540620A (ja) 2008-11-20
TW200716633A (en) 2007-05-01
JO2753B1 (en) 2014-03-15
FR2885904A1 (fr) 2006-11-24
NZ563239A (en) 2011-01-28
AU2006248825B2 (en) 2012-02-23
UA93203C2 (ru) 2011-01-25
EA200702531A1 (ru) 2008-04-28
CR9515A (es) 2008-02-21
AU2006248825A1 (en) 2006-11-23
CA2608378A1 (fr) 2006-11-23
IL187163A (en) 2014-07-31
KR20080025375A (ko) 2008-03-20
PE20061367A1 (es) 2007-01-08
BRPI0611424A2 (pt) 2010-09-08
AR054125A1 (es) 2007-06-06
FR2885904B1 (fr) 2007-07-06
CN101203518B (zh) 2013-07-24

Similar Documents

Publication Publication Date Title
NO20076460L (no) Nye fluorenderivater, sammensetninger inneholdende nevnte derivater og anvendelse derav
NO20074634L (no) Substituerte heterocykler og deres anvendelse som CHK1-, PDK1- og PAK-inhibitorer
NO20055421L (no) Kinolinderivater som fosfodiestrase-inhibitorer
NO20083214L (no) Pyrimidinylarylurea-derivater som omdannes til FGF-inhibitorer
NO20071074L (no) Substituerte cykliske ureaderivater, fremstilling derav og farmasoytisk anvendelse derav som kinaseinhibitorer
NO20081893L (no) 4-(3-aminopyrazol)pyrimidinderivater til anvendelse som tyrosin-kinaseinhibitorer i behandling av kreft
NO20050828L (no) lndol-3-svovelderivater
NO20071137L (no) Nye piperidinderivater for behandling av depresjon
NO20071073L (no) Heterocykel-substituerte cykliske ureaderivater, fremstilling derav og farmasoytisk anvendelse derav som kinaseinhibitorer
NO20080981L (no) Nitrocatechol-derivater som COMT-inhibitorer
NO20071504L (no) Pyrimidinderivanter.
NO20071593L (no) Pyrimidinderivater
NO20090628L (no) Pyridizinon derivativater
MX2009011964A (es) Derivados heterociclicos pirrolo-nitrogenosos, su preparacion y uso farmaceutico.
NO20084418L (no) Azolopyridin-3-on derivater som inhibitorer av endoteliallipase
NO20051165L (no) Benzotiazolderivater som har -adrenoerseptorantagonist aktivitet
NO20073791L (no) Pyrazolylaminopyridinderivater anvendbare som kinaseinhibitorer
NO20062020L (no) 1-amino-2-oksysubstituerte tetrahydronaftalenderivater, fremgangsmate for fremstilling derav, og deres anvendelse som antiflogistika
NO20084845L (no) 2-pyrazinonderivater for behandling av sykdom eller tilstander der inhibiering av neutrofil elastaseaktivitetet er gunstig
NO20063821L (no) Kinolinderivater for anvendelse som mykobakterielle inhibitorer
NO20071320L (no) Pyrazolsubstituerte aminoheteroarylforbindelser som protein kinase inhibitorer.
MY148375A (en) Delta and epsilon crystal forms of imatinib mesylate
NO20070224L (no) 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
NO20064201L (no) Glukopyranosylsubstituerte benzolderivater, medikamenter inneholdende slike forbindelser, deres anvendelse og fremstilling
NO20083427L (no) Cystoksiske midler omfattende nye tomaymycinderivater og deres terapeutiske anvendelse

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application