NO20073731L - Fast doseringsform omfattende protonpumpeinhibitor, og suspensjon fremstilt derav - Google Patents

Fast doseringsform omfattende protonpumpeinhibitor, og suspensjon fremstilt derav

Info

Publication number
NO20073731L
NO20073731L NO20073731A NO20073731A NO20073731L NO 20073731 L NO20073731 L NO 20073731L NO 20073731 A NO20073731 A NO 20073731A NO 20073731 A NO20073731 A NO 20073731A NO 20073731 L NO20073731 L NO 20073731L
Authority
NO
Norway
Prior art keywords
suspension
dosage form
proton pump
pump inhibitor
prepared therefrom
Prior art date
Application number
NO20073731A
Other languages
English (en)
Inventor
Eva Trofast
Eva Persson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36602062&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20073731(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20073731L publication Critical patent/NO20073731L/no

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
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    • A61K9/1605—Excipients; Inactive ingredients
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    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biochemistry (AREA)
  • Otolaryngology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

En fast raskt gelerende oral farmasøytisk doseringsform, så vel som vandige suspensjoner fremstilt derfra, som innbefatter en sur syresensitiv protonpumpeinhibitor som aktiv ingrediens fordelt i et antall enterisk belagte pellets og et suspensjonsmodifiserende granulat som innbefatter et raskt oppløsende fortynningsmiddel granulert sammen med et geleringsmiddel valgt fra xantangummi, og et surt pH regulerende middel og et bindemiddel. Det suspensjonsmodifiserende granulatet blir raskt desintegrert og gelert når det suspenderes i et vandig medium og danner således en homogen stabil og robust suspensjon som har en reproduserbar og stabil viskositet. Videre angår oppfinnelsen en forbedret fremgangsmåte for fremstilling og anvendelse av slik formulering ved medisinsk behandling som inkluderer hindring av gastrointestinale forstyrrelser hos mennesker.
NO20073731A 2004-12-22 2007-07-18 Fast doseringsform omfattende protonpumpeinhibitor, og suspensjon fremstilt derav NO20073731L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63843504P 2004-12-22 2004-12-22
PCT/SE2005/001972 WO2006068596A1 (en) 2004-12-22 2005-12-20 Solid dosage form comprising proton pump inhibitor and suspension made thereof

Publications (1)

Publication Number Publication Date
NO20073731L true NO20073731L (no) 2007-09-24

Family

ID=36602062

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073731A NO20073731L (no) 2004-12-22 2007-07-18 Fast doseringsform omfattende protonpumpeinhibitor, og suspensjon fremstilt derav

Country Status (30)

Country Link
US (5) US20060134210A1 (no)
EP (1) EP1830816B1 (no)
JP (1) JP5171259B2 (no)
KR (1) KR101321641B1 (no)
CN (1) CN101087590B (no)
AR (1) AR052173A1 (no)
AU (1) AU2005319732B2 (no)
BR (1) BRPI0519186A2 (no)
CA (1) CA2592030C (no)
CY (1) CY1113207T1 (no)
DK (1) DK1830816T3 (no)
ES (1) ES2389844T3 (no)
HK (2) HK1111609A1 (no)
HR (1) HRP20120719T1 (no)
IL (1) IL183658A (no)
ME (1) ME01458B (no)
MX (1) MX2007007423A (no)
MY (1) MY149156A (no)
NO (1) NO20073731L (no)
NZ (1) NZ555833A (no)
PL (1) PL1830816T3 (no)
PT (1) PT1830816E (no)
RS (1) RS52472B (no)
RU (1) RU2397756C2 (no)
SA (1) SA05260421B1 (no)
SI (1) SI1830816T1 (no)
TW (1) TWI478735B (no)
UA (1) UA87341C2 (no)
WO (1) WO2006068596A1 (no)
ZA (1) ZA200705113B (no)

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