NO20073655L - Antistoffer mot IL-13 reseptor alfa 1 og anvendelser derav - Google Patents
Antistoffer mot IL-13 reseptor alfa 1 og anvendelser deravInfo
- Publication number
- NO20073655L NO20073655L NO20073655A NO20073655A NO20073655L NO 20073655 L NO20073655 L NO 20073655L NO 20073655 A NO20073655 A NO 20073655A NO 20073655 A NO20073655 A NO 20073655A NO 20073655 L NO20073655 L NO 20073655L
- Authority
- NO
- Norway
- Prior art keywords
- antibodies
- receptor alpha
- antibody
- heavy chain
- variable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Et antistoff som binder til IL-13Ra1, hemmer IL-13 bioaktivitet og omfatter en variabel tung og en variabel lett kjede, karakterisert ved at den variable tung kjede aminosyresekvensen CDR3 av nevnte antistoff er valgt fra gruppen bestående av tung kjede CDR3-sekvensene av SEKV ID NR: 1, 3, 5, 7 eller 9 er anvendelige ved behandling av astma og allergiske sykdommer.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05000003 | 2005-01-03 | ||
EP05002229 | 2005-02-03 | ||
PCT/EP2006/000005 WO2006072564A1 (en) | 2005-01-03 | 2006-01-02 | Antibodies against il-13 receptor alpha 1 and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20073655L true NO20073655L (no) | 2007-08-02 |
Family
ID=36199730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20073655A NO20073655L (no) | 2005-01-03 | 2007-07-17 | Antistoffer mot IL-13 reseptor alfa 1 og anvendelser derav |
Country Status (20)
Country | Link |
---|---|
US (2) | US7807158B2 (no) |
EP (1) | EP1836226B1 (no) |
JP (1) | JP5086098B2 (no) |
KR (1) | KR100934894B1 (no) |
AR (1) | AR051888A1 (no) |
AT (1) | ATE513855T1 (no) |
AU (1) | AU2006204480B2 (no) |
BR (1) | BRPI0606368A2 (no) |
CA (1) | CA2592614C (no) |
CR (1) | CR9209A (no) |
HK (1) | HK1112006A1 (no) |
IL (1) | IL184205A0 (no) |
MA (1) | MA29226B1 (no) |
MX (1) | MX2007008128A (no) |
NO (1) | NO20073655L (no) |
NZ (1) | NZ556126A (no) |
RU (1) | RU2413736C2 (no) |
SG (1) | SG172504A1 (no) |
TW (2) | TWI306862B (no) |
WO (1) | WO2006072564A1 (no) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR045563A1 (es) | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
RU2445318C2 (ru) * | 2006-10-02 | 2012-03-20 | Ридженерон Фармасьютикалз, Инк. | Высокоаффинные антитела человека к рецептору il-4 человека |
US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
WO2008060814A2 (en) * | 2006-10-19 | 2008-05-22 | Merck & Co., Inc. | ANTI-IL-13Rα1 ANTIBODIES AND THEIR USES THEREOF |
AU2007319604B2 (en) | 2006-10-19 | 2011-03-24 | Csl Limited | High affinity antibody antagonists of interleukin-13 receptor alpha 1 |
JP2010507366A (ja) * | 2006-10-19 | 2010-03-11 | メルク アンド カンパニー インコーポレイテッド | インターロイキン−13受容体α1の抗体アンタゴニスト |
KR101226353B1 (ko) | 2007-06-01 | 2013-01-24 | 에프. 호프만-라 로슈 아게 | 면역글로불린 정제 |
CA2693611A1 (en) * | 2007-07-10 | 2009-01-15 | F. Hoffmann-La Roche Ag | Novel formulation |
AU2008309934B2 (en) | 2007-10-12 | 2014-03-06 | F. Hoffmann-La Roche Ag | Protein expression from multiple nucleic acids |
EP2050764A1 (en) * | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
CN103399145B (zh) | 2007-12-15 | 2015-06-24 | 霍夫曼-拉罗奇有限公司 | 区分测定 |
ES2932874T3 (es) * | 2009-03-25 | 2023-01-27 | Genentech Inc | Anticuerpos anti-FGFR3 y métodos que utilizan los mismos |
EP2431463A4 (en) * | 2009-05-13 | 2012-12-26 | Shionogi & Co | TESTS FOR VISCERAL ADIPOSITAS AND ITS USE |
CA2768326C (en) | 2009-07-30 | 2019-01-08 | F. Hoffmann-La Roche Ag | Moveable chromatography column separator |
AU2010302662B2 (en) | 2009-10-01 | 2015-11-26 | F. Hoffmann-La Roche Ag | Multistep final filtration |
WO2011038894A1 (en) | 2009-10-01 | 2011-04-07 | F. Hoffmann-La Roche Ag | Protein a chromatography |
BR112012005668A2 (pt) | 2009-10-19 | 2020-10-13 | F. Hoffmann La Roche Ag | '' linhagem celular, anticorpo, uso de um anticorpo, kit, método de detecção de um anticorpo terapêutico, método de determinação imunológica de um anticorpo terapêutico, composição de anticorpo, uso de uma composição de anticorpo'' |
MX2012006626A (es) | 2009-12-22 | 2012-06-25 | Hoffmann La Roche | Agregacion dependiente de secuencia. |
JP5766286B2 (ja) | 2010-08-17 | 2015-08-19 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 抗ヒトIgG1抗体 |
JP6073811B2 (ja) | 2011-02-02 | 2017-02-01 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | クロマトグラフィーカラムサポート |
KR20140059168A (ko) | 2011-04-21 | 2014-05-15 | 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 | 시신경 척수염 치료용 조성물 및 치료 방법 |
CN110624107A (zh) | 2012-08-21 | 2019-12-31 | 赛诺菲生物技术公司 | 通过施用il-4r拮抗剂治疗或预防哮喘的方法 |
TWI697334B (zh) | 2013-06-04 | 2020-07-01 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
PL3010539T3 (pl) | 2013-06-21 | 2020-01-31 | Sanofi Biotechnology | Sposoby leczenia polipowatości nosa przez podawanie antagonisty il-4r |
JP6563910B2 (ja) | 2013-07-04 | 2019-08-21 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 血清サンプル中の抗薬物抗体を検出するための干渉抑制イムノアッセイ |
TWI682781B (zh) | 2013-07-11 | 2020-01-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
US8986691B1 (en) | 2014-07-15 | 2015-03-24 | Kymab Limited | Method of treating atopic dermatitis or asthma using antibody to IL4RA |
US8980273B1 (en) | 2014-07-15 | 2015-03-17 | Kymab Limited | Method of treating atopic dermatitis or asthma using antibody to IL4RA |
CN105829344B (zh) | 2013-12-20 | 2021-12-07 | 英特维特国际股份有限公司 | 犬化鼠抗犬pd-1抗体 |
CA2940295A1 (en) | 2014-02-21 | 2015-08-27 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an il-4r antagonist |
WO2015130975A1 (en) | 2014-02-28 | 2015-09-03 | Regeneron Pharmaceuticals, Inc. | Methods for treating skin infection by administering an il-4r antagonist |
ES2853823T3 (es) | 2014-09-30 | 2021-09-17 | Intervet Int Bv | Anticuerpos de PD-L1 que se unen a PD-L1 canino |
KR20170081262A (ko) | 2014-11-14 | 2017-07-11 | 사노피 바이오테크놀로지 | Il-4r 길항제의 투여에 의한, 비용종을 동반한 만성 부비동염의 치료 방법 |
JP6968055B2 (ja) | 2015-08-21 | 2021-11-17 | ジェネンテック, インコーポレイテッド | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
PL3337817T3 (pl) | 2015-08-21 | 2022-01-17 | F. Hoffmann-La Roche Ag | Sposób zmniejszania zawartości białek komórek gospodarza w chromatografii powinowactwa |
US11091556B2 (en) | 2015-12-18 | 2021-08-17 | Intervet Inc. | Caninized human antibodies to human IL-4R alpha |
WO2018011405A1 (en) * | 2016-07-15 | 2018-01-18 | Universität Zürich | Il-13ralpha1 antibodies for use in treatment of atopic inflammation, sepsis and neutropenia |
JP2019531273A (ja) | 2016-09-01 | 2019-10-31 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | Il−4rアンタゴニストを投与することによりアレルギーを予防又は処置するための方法 |
JOP20190009A1 (ar) | 2016-09-21 | 2019-01-27 | Alx Oncology Inc | أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها |
WO2018057776A1 (en) | 2016-09-22 | 2018-03-29 | Regeneron Pharmaceuticals, Inc. | Methods for treating severe atopic dermatitis by administering an il-4r inhibitor |
TWI784988B (zh) | 2016-12-01 | 2022-12-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
WO2018106959A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
WO2018183932A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor |
WO2019028367A1 (en) | 2017-08-04 | 2019-02-07 | Regeneron Pharmaceuticals, Inc. | METHODS OF TREATING ESOPHAGITIS WITH ACTIVE EOSINOPHILES |
US11034768B2 (en) | 2017-10-30 | 2021-06-15 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an IL-4R antagonist |
KR20200133376A (ko) | 2018-03-21 | 2020-11-27 | 알렉소 온콜로지 인크. | 신호-조절 단백질 알파에 대한 항체 및 사용 방법 |
US11292847B2 (en) | 2018-05-13 | 2022-04-05 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an IL-4R inhibitor |
WO2020106757A1 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
MA55372A (fr) | 2019-03-21 | 2022-01-26 | Regeneron Pharma | Combinaison d'inhibiteurs de la voie il-4/il-13 et d'ablation de plasmocytes pour traiter une allergie |
AU2020247175A1 (en) | 2019-03-26 | 2021-10-14 | Aslan Pharmaceuticals Pte Ltd | Treatment employing anti-IL-13R antibody or binding fragment thereof |
US11504426B2 (en) | 2019-08-05 | 2022-11-22 | Regeneron Pharmaceuticals, Inc. | Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R antagonist |
US11707610B2 (en) | 2019-12-13 | 2023-07-25 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
WO2022186773A1 (en) | 2021-03-01 | 2022-09-09 | Aslan Pharmaceuticals Pte Ltd | TREATMENT OF ATOPIC DERMATITIS EMPLOYING ANTI-IL-13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF IN AN ALLERGIC POPULATION |
WO2022186772A1 (en) | 2021-03-01 | 2022-09-09 | Aslan Pharmaceuticals Pte Ltd | TREATMENT OF ATOPIC DERMATITIS EMPLOYING ANTI-IL-13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF |
WO2023048651A1 (en) | 2021-09-27 | 2023-03-30 | Aslan Pharmaceuticals Pte Ltd | Method for treatment of moderate to severe atoptic dematitis |
WO2023048650A1 (en) | 2021-09-27 | 2023-03-30 | Aslan Pharmaceuticals Pte Ltd | TREATMENT OF PRURITIS EMPLOYING ANTI-IL13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF |
WO2023075702A1 (en) | 2021-10-29 | 2023-05-04 | Aslan Pharmaceuticals Pte Ltd | Anti-il-13r antibody formulation |
WO2024043837A1 (en) | 2022-08-26 | 2024-02-29 | Aslan Pharmaceuticals Pte Ltd | High concentration anti-il13r antibody formulation |
WO2024054157A1 (en) | 2022-09-06 | 2024-03-14 | Aslan Pharmaceuticals Pte Ltd | Treatment for sleep loss or sleep disturbance in patients with dermatitis |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
US5770429A (en) * | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5614191A (en) | 1995-03-15 | 1997-03-25 | The United States Of America As Represented By The Department Of Health And Human Services | IL-13 receptor specific chimeric proteins and uses thereof |
ES2334408T3 (es) | 1995-10-23 | 2010-03-09 | Zenyth Operations Pty Ltd | Receptor de hematopoyetina y secuencias geneticas que lo codifican. |
US5843659A (en) * | 1996-03-21 | 1998-12-01 | Apoptosis Technology, Inc. | Apoptosis gene EI24, compositions, and methods of use |
US20050154192A1 (en) | 2001-11-27 | 2005-07-14 | Kamon Shirakawa | Anti-il13 receptor alpha1 neutralizing antibody |
AR037756A1 (es) * | 2001-12-17 | 2004-12-01 | Bayer Corp | Anticuerpo que inhibe la actividad del factor de las celulas precursoras y su uso para el tratamiento del asma. |
WO2003080675A2 (en) | 2002-03-22 | 2003-10-02 | Amrad Operations Pty Ltd | MONOCLONAL ANTIBODY AGAINST INTERLEUKIN-13 RECEPTOR ALPHA 1 (IL-13Rα1) |
US7625699B2 (en) * | 2003-03-10 | 2009-12-01 | Celera Corporation | Genetic polymorphisms associated with coronary stenosis, methods of detection and uses thereof |
NZ599196A (en) * | 2003-07-15 | 2014-01-31 | Amgen Inc | Human anti-ngf neutralizing antibodies as selective ngf pathway inhibitors |
-
2005
- 2005-12-30 TW TW094147847A patent/TWI306862B/zh not_active IP Right Cessation
- 2005-12-30 TW TW097137970A patent/TW200902555A/zh unknown
-
2006
- 2006-01-02 SG SG2009087206A patent/SG172504A1/en unknown
- 2006-01-02 BR BRPI0606368-3A patent/BRPI0606368A2/pt not_active IP Right Cessation
- 2006-01-02 EP EP06706157A patent/EP1836226B1/en active Active
- 2006-01-02 WO PCT/EP2006/000005 patent/WO2006072564A1/en active Application Filing
- 2006-01-02 CA CA2592614A patent/CA2592614C/en not_active Expired - Fee Related
- 2006-01-02 NZ NZ556126A patent/NZ556126A/en not_active IP Right Cessation
- 2006-01-02 KR KR1020077015296A patent/KR100934894B1/ko not_active IP Right Cessation
- 2006-01-02 AT AT06706157T patent/ATE513855T1/de not_active IP Right Cessation
- 2006-01-02 JP JP2007548835A patent/JP5086098B2/ja not_active Expired - Fee Related
- 2006-01-02 MX MX2007008128A patent/MX2007008128A/es active IP Right Grant
- 2006-01-02 AU AU2006204480A patent/AU2006204480B2/en not_active Expired - Fee Related
- 2006-01-02 RU RU2007129676/10A patent/RU2413736C2/ru not_active IP Right Cessation
- 2006-01-03 US US11/325,197 patent/US7807158B2/en not_active Expired - Fee Related
- 2006-01-03 AR ARP060100010A patent/AR051888A1/es unknown
-
2007
- 2007-06-25 IL IL184205A patent/IL184205A0/en unknown
- 2007-06-26 CR CR9209A patent/CR9209A/es not_active Application Discontinuation
- 2007-07-06 MA MA30048A patent/MA29226B1/fr unknown
- 2007-07-17 NO NO20073655A patent/NO20073655L/no not_active Application Discontinuation
-
2008
- 2008-06-23 HK HK08106940.0A patent/HK1112006A1/xx not_active IP Right Cessation
-
2010
- 2010-07-26 US US12/843,225 patent/US20110086026A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20070091180A (ko) | 2007-09-07 |
ATE513855T1 (de) | 2011-07-15 |
KR100934894B1 (ko) | 2010-01-07 |
RU2413736C2 (ru) | 2011-03-10 |
MA29226B1 (fr) | 2008-02-01 |
NZ556126A (en) | 2008-09-26 |
AU2006204480A1 (en) | 2006-07-13 |
CA2592614A1 (en) | 2006-07-13 |
RU2007129676A (ru) | 2009-02-10 |
BRPI0606368A2 (pt) | 2009-06-23 |
MX2007008128A (es) | 2007-07-20 |
SG172504A1 (en) | 2011-07-28 |
US20110086026A1 (en) | 2011-04-14 |
TW200902555A (en) | 2009-01-16 |
EP1836226B1 (en) | 2011-06-22 |
AU2006204480B2 (en) | 2011-06-09 |
CA2592614C (en) | 2015-04-14 |
TWI306862B (en) | 2009-03-01 |
US20060263356A1 (en) | 2006-11-23 |
IL184205A0 (en) | 2007-10-31 |
US7807158B2 (en) | 2010-10-05 |
JP5086098B2 (ja) | 2012-11-28 |
TW200635945A (en) | 2006-10-16 |
AR051888A1 (es) | 2007-02-14 |
EP1836226A1 (en) | 2007-09-26 |
JP2008526187A (ja) | 2008-07-24 |
WO2006072564A1 (en) | 2006-07-13 |
CR9209A (es) | 2007-08-28 |
HK1112006A1 (en) | 2008-08-22 |
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