NO20072767L - Gabapentin prodrug vedvarende frigivelse orale doseringsformer - Google Patents
Gabapentin prodrug vedvarende frigivelse orale doseringsformerInfo
- Publication number
- NO20072767L NO20072767L NO20072767A NO20072767A NO20072767L NO 20072767 L NO20072767 L NO 20072767L NO 20072767 A NO20072767 A NO 20072767A NO 20072767 A NO20072767 A NO 20072767A NO 20072767 L NO20072767 L NO 20072767L
- Authority
- NO
- Norway
- Prior art keywords
- dosage forms
- sustained release
- oral dosage
- release oral
- gabapentin
- Prior art date
Links
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 6
- 229960002870 gabapentin Drugs 0.000 title abstract 3
- 239000006186 oral dosage form Substances 0.000 title abstract 2
- 239000000651 prodrug Substances 0.000 title abstract 2
- 229940002612 prodrug Drugs 0.000 title abstract 2
- 238000013268 sustained release Methods 0.000 title abstract 2
- 239000012730 sustained-release form Substances 0.000 title abstract 2
- 230000006806 disease prevention Effects 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- TZDUHAJSIBHXDL-UHFFFAOYSA-N gabapentin enacarbil Chemical compound CC(C)C(=O)OC(C)OC(=O)NCC1(CC(O)=O)CCCCC1 TZDUHAJSIBHXDL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K31/225—Polycarboxylic acids
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- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Inorganic Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Vedvarende frigivelse oral doseringsformer av et gabapentin prodrug av 1-{[(a-isobutanoyloksyetoksy)karbonyl]aminometyl}-1-sykloheksan eddiksyre er beskrevet. Doseringsformene er anvendelige for forebygging av sykdommer og forstyrrelser hvor gabapentin er terapeutisk effektivt.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62573704P | 2004-11-04 | 2004-11-04 | |
PCT/US2005/040127 WO2006050514A1 (en) | 2004-11-04 | 2005-11-03 | Gabapentin prodrug sustained release oral dosage forms |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20072767L true NO20072767L (no) | 2007-07-27 |
NO338688B1 NO338688B1 (no) | 2016-10-03 |
Family
ID=35929688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20072767A NO338688B1 (no) | 2004-11-04 | 2007-05-31 | Gabapentin prodrug vedvarende frigivelse orale doseringsformuleringer |
Country Status (17)
Country | Link |
---|---|
US (8) | US8795725B2 (no) |
EP (1) | EP1811986B1 (no) |
JP (2) | JP2008518971A (no) |
KR (1) | KR101228399B1 (no) |
CN (2) | CN102429882B (no) |
AU (1) | AU2005301970B2 (no) |
BR (1) | BRPI0517227B8 (no) |
CA (1) | CA2584338C (no) |
HK (1) | HK1104798A1 (no) |
IL (1) | IL182964A0 (no) |
MX (1) | MX2007005306A (no) |
NO (1) | NO338688B1 (no) |
NZ (1) | NZ554737A (no) |
RU (1) | RU2440112C2 (no) |
TW (1) | TWI377938B (no) |
WO (1) | WO2006050514A1 (no) |
ZA (1) | ZA200703571B (no) |
Families Citing this family (25)
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US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US8048917B2 (en) * | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US7025745B2 (en) * | 2002-10-07 | 2006-04-11 | Advanced Cardiovascular Systems, Inc. | Method of making a catheter balloon using a tapered mandrel |
JP2007505149A (ja) * | 2003-09-11 | 2007-03-08 | ゼノポート,インコーポレイティド | ギャバ類似体のプロドラッグを用いる尿失禁の治療および/あるいは予防 |
CN1871021B (zh) * | 2003-09-17 | 2010-07-28 | 什诺波特有限公司 | 用gaba类似物的前药治疗或预防多动腿综合征 |
JP4308263B2 (ja) | 2003-10-14 | 2009-08-05 | ゼノポート,インコーポレイティド | γ−アミノ酪酸アナログの結晶形 |
MX2007005306A (es) | 2004-11-04 | 2007-06-11 | Xenoport Inc | Formas de dosis oral de liberacion sostenida de la prodroga gabapentina. |
CA2612292C (en) * | 2005-06-20 | 2013-09-03 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use |
WO2007027477A2 (en) * | 2005-08-23 | 2007-03-08 | Xenoport, Inc. | Treating vulvodynia using prodrugs of gaba analogs |
EP1928450A2 (en) * | 2005-08-26 | 2008-06-11 | Xenoport, Inc. | Treating premature ejaculation using gabapentin and pregabalin prodrugs |
MX2009006080A (es) * | 2006-12-08 | 2009-07-14 | Xenoport Inc | Uso de profarmacos de analogos de gaba para el tratamiento de enfermedades. |
ES2365574T3 (es) * | 2007-01-11 | 2011-10-07 | Xenoport, Inc. | Formas de dosificación oral para liberación continua de un profármaco de r-baclofeno y procedimientos de tratamiento. |
WO2010101115A1 (ja) | 2009-03-02 | 2010-09-10 | アステラス製薬株式会社 | 固形製剤の包装体 |
NZ594648A (en) * | 2009-03-03 | 2013-12-20 | Xenoport Inc | Sustained release oral dosage forms of an r-baclofen prodrug |
JP5580345B2 (ja) * | 2009-03-06 | 2014-08-27 | ゼノポート,インコーポレイティド | 高充填量のガバペンチンプロドラッグを有する経口剤形 |
WO2011028234A1 (en) * | 2009-09-04 | 2011-03-10 | Xenoport, Inc. | Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid |
WO2011091164A1 (en) * | 2010-01-22 | 2011-07-28 | Xenoport, Inc. | Oral dosage forms having a high loading of a tranexamic acid prodrug |
JP5936542B2 (ja) | 2010-09-01 | 2016-06-22 | アステラス製薬株式会社 | 包装体 |
CN104042597A (zh) * | 2013-03-13 | 2014-09-17 | 苏州朗易生物医药研究有限公司 | 一种治疗神经痛的药物组合物及其制备方法 |
AU2016328150B2 (en) | 2015-09-23 | 2020-10-01 | Xw Laboratories Inc. | Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof |
BR102017028213B1 (pt) | 2017-12-27 | 2022-07-19 | Loccitane Do Brasil S.A. | Composição cosmética compreende óleo de licuri, uso da dita composição e método cosmético |
WO2020165633A1 (en) * | 2019-02-11 | 2020-08-20 | Glenmark Pharmaceuticals Limited | A pharmaceutical composition of gabapentin enacarbil or salt thereof |
CN114306234A (zh) * | 2021-12-23 | 2022-04-12 | 江苏百奥信康医药科技有限公司 | 一种含有加巴喷丁复合物的tpgs胶束口服液及其制备方法 |
CN114288246A (zh) * | 2021-12-23 | 2022-04-08 | 江苏百奥信康医药科技有限公司 | 一种含有加巴喷丁复合物的聚合物胶束口服液及其制备方法 |
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