NO20070675L - Sammenspleisede benzamidforbindelser og inhibitorer av vanilloid-reseptorundergruppe 1 (VR1) aktivitet - Google Patents

Sammenspleisede benzamidforbindelser og inhibitorer av vanilloid-reseptorundergruppe 1 (VR1) aktivitet

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Publication number
NO20070675L
NO20070675L NO20070675A NO20070675A NO20070675L NO 20070675 L NO20070675 L NO 20070675L NO 20070675 A NO20070675 A NO 20070675A NO 20070675 A NO20070675 A NO 20070675A NO 20070675 L NO20070675 L NO 20070675L
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NO
Norway
Prior art keywords
activity
vanilloid receptor
pain
inhibitors
benzamide compound
Prior art date
Application number
NO20070675A
Other languages
English (en)
Inventor
Yoshikazu Hori
Yoshihisa Koga
Takashi Watanabe
Shinji Yata
Takayuki Yamasaki
Masahiro Sakata
Wataru Kondo
Hidekazu Ozeki
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of NO20070675L publication Critical patent/NO20070675L/no

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    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Å tilveiebringe en forbindelse som har en utmerket inhiberende effekt på vanilloidresep-torsubtype 1 (VRI) -aktivitet som er effektiv i å behandle sykdommer hvor vanilloidre-septorsubtype 1 (VRI) -aktiviteten er involvert, slik som smerte, akutt smerte, kronisk smerte, neuropatisk smerte, reumatoid artrittsmerte, neuralgi osv., og en farmasøytisk sammensetning som inneholder forbindelsen. Hensikten har blitt oppnådd ved en kondensert benzamidforbindelse representert ved den følgende formelen (symbolene i formelen har de samme betydningene som definert i spesifikasjonen) eller dens salt:
NO20070675A 2004-07-15 2007-02-06 Sammenspleisede benzamidforbindelser og inhibitorer av vanilloid-reseptorundergruppe 1 (VR1) aktivitet NO20070675L (no)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2004208334 2004-07-15
US59018004P 2004-07-22 2004-07-22
JP2004379551 2004-12-28
US64187405P 2005-01-06 2005-01-06
JP2005133724 2005-04-28
US68007205P 2005-05-12 2005-05-12
PCT/JP2005/013446 WO2006006741A1 (ja) 2004-07-15 2005-07-14 縮合ベンズアミド化合物及びバニロイド受容体１型(ｖｒ１)活性阻害剤

Publications (1)

Publication Number Publication Date
NO20070675L true NO20070675L (no) 2007-03-26

Family

ID=43760043

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070675A NO20070675L (no) 2004-07-15 2007-02-06 Sammenspleisede benzamidforbindelser og inhibitorer av vanilloid-reseptorundergruppe 1 (VR1) aktivitet

Country Status (14)

Country Link
US (1) US8008292B2 (no)
EP (2) EP1777225A4 (no)
JP (1) JP4018739B2 (no)
KR (1) KR101042490B1 (no)
CN (1) CN1984906A (no)
AU (1) AU2005260821B2 (no)
BR (1) BRPI0513286A (no)
CA (1) CA2571133C (no)
IL (1) IL180112A0 (no)
MX (1) MX2007000480A (no)
NO (1) NO20070675L (no)
NZ (1) NZ552086A (no)
RU (1) RU2392278C2 (no)
WO (1) WO2006006741A1 (no)

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NZ552086A (en) 2009-12-24
KR101042490B1 (ko) 2011-06-16
US8008292B2 (en) 2011-08-30
RU2007105595A (ru) 2008-08-20
EP1777225A1 (en) 2007-04-25
EP2314585A1 (en) 2011-04-27
EP2314585B1 (en) 2012-09-12
EP1777225A4 (en) 2009-06-24
JP4018739B2 (ja) 2007-12-05
AU2005260821B2 (en) 2010-02-18
US20060035882A1 (en) 2006-02-16
IL180112A0 (en) 2007-06-03
JPWO2006006741A1 (ja) 2008-05-01
KR20070043777A (ko) 2007-04-25
BRPI0513286A (pt) 2008-05-06
AU2005260821A1 (en) 2006-01-19
CA2571133A1 (en) 2006-01-19
MX2007000480A (es) 2007-03-29
CN1984906A (zh) 2007-06-20
CA2571133C (en) 2011-04-19
WO2006006741A1 (ja) 2006-01-19

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