NO20054892L - Anti-IL-22RA-antistoffer og bindingspartnere og fremgangsmater for anvendelse ved inflammasjon - Google Patents

Anti-IL-22RA-antistoffer og bindingspartnere og fremgangsmater for anvendelse ved inflammasjon

Info

Publication number
NO20054892L
NO20054892L NO20054892A NO20054892A NO20054892L NO 20054892 L NO20054892 L NO 20054892L NO 20054892 A NO20054892 A NO 20054892A NO 20054892 A NO20054892 A NO 20054892A NO 20054892 L NO20054892 L NO 20054892L
Authority
NO
Norway
Prior art keywords
antibodies
binding partners
methods
inflammation
antagonizing
Prior art date
Application number
NO20054892A
Other languages
English (en)
Norwegian (no)
Other versions
NO20054892D0 (no
Inventor
Anthony W Siadak
Wenfeng Xu
Wayne Kindsvogel
Yasmin Chandraksekher
Stacey R Dillion
Joyce M Lehner
Pallavur V Sivakumar
Margaret S Moore
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33101289&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20054892(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of NO20054892D0 publication Critical patent/NO20054892D0/no
Publication of NO20054892L publication Critical patent/NO20054892L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20054892A 2003-03-24 2005-10-21 Anti-IL-22RA-antistoffer og bindingspartnere og fremgangsmater for anvendelse ved inflammasjon NO20054892L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45748103P 2003-03-24 2003-03-24
US52329503P 2003-11-17 2003-11-17
PCT/US2004/008956 WO2004085476A2 (fr) 2003-03-24 2004-03-24 Anticorps anti-il-22ra et leurs partenaires de liaison, methodes d'utilisation de ces derniers dans les cas d'inflammation

Publications (2)

Publication Number Publication Date
NO20054892D0 NO20054892D0 (no) 2005-10-21
NO20054892L true NO20054892L (no) 2005-12-23

Family

ID=33101289

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20054892A NO20054892L (no) 2003-03-24 2005-10-21 Anti-IL-22RA-antistoffer og bindingspartnere og fremgangsmater for anvendelse ved inflammasjon

Country Status (16)

Country Link
US (6) US20040209330A1 (fr)
EP (2) EP1606317B1 (fr)
JP (2) JP2007525437A (fr)
KR (3) KR20110091598A (fr)
CN (2) CN103864934A (fr)
AT (1) ATE475673T1 (fr)
AU (2) AU2004223837C1 (fr)
BR (2) BRPI0408705A (fr)
CA (2) CA2519057A1 (fr)
DE (1) DE602004028347D1 (fr)
DK (1) DK1606317T3 (fr)
EA (2) EA009026B1 (fr)
ES (1) ES2347657T3 (fr)
MX (2) MXPA05010136A (fr)
NO (1) NO20054892L (fr)
WO (2) WO2004085475A2 (fr)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
US6610286B2 (en) 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
AU2001290524A1 (en) * 2000-08-08 2002-02-18 Zymogenetics Inc. Soluble zcytor 11 cytokine receptors
ATE460429T1 (de) 2000-09-15 2010-03-15 Zymogenetics Inc Polypeptide enthaltend extrazellulären domäne von il-20ra und/oderr il-20rb
JP4532902B2 (ja) 2001-12-17 2010-08-25 ザイモジェネティクス,インコーポレイティド 子宮頸部癌の治療方法
EA009026B1 (ru) 2003-03-24 2007-10-26 Займоджинетикс, Инк. Антитела против il-22ra, их партнеры по связыванию и способы их применения при воспалениях
EP1692180B1 (fr) * 2003-11-21 2009-11-04 ZymoGenetics, Inc. Anticorps et partenaires de liaison anti-il 20 et procedes d'utilisation dans l'inflammation
JP2008515808A (ja) * 2004-10-04 2008-05-15 トリニティ バイオシステムズ インコーポレーテッド 針不用の高分子送達のための方法及び組成物
EP1812476B1 (fr) * 2004-10-22 2010-07-21 ZymoGenetics, Inc. Anticorps anti-il-22ra et partenaires de liaison et methodes d'utilisation de ces anticorps et de ces partenaires de liaison pour le traitement de maladies inflammatoires
CN100515491C (zh) * 2005-01-04 2009-07-22 健能隆医药技术(上海)有限公司 白介素-22的医药用途
JP2008532931A (ja) * 2005-02-08 2008-08-21 ザイモジェネティクス, インコーポレイテッド 抗il−20、抗il−22および抗il−22ra抗体ならびに結合パートナー、ならびに炎症における使用法
CA2631961A1 (fr) * 2005-12-02 2007-11-08 Genentech, Inc. Compositions et methodes de traitement des maladies et troubles associes au signalement des cytokines portant sur les anticorps qui se lient a il-22
CA2631981A1 (fr) * 2005-12-05 2007-06-14 Trinity Biosystems, Inc. Procedes et compositions d'apport sans aiguille de partenaires de liaison
US7666991B2 (en) * 2005-12-05 2010-02-23 Trinity Biosystems, Inc. Compositions for needleless delivery of antibodies
US20090148440A1 (en) * 2005-12-22 2009-06-11 Dhy & Co., Ltd. Antibodies against interleukin-22 binding protein and its uses for the treatment of metabolic disorders
US20090305978A1 (en) * 2006-03-16 2009-12-10 Trinity Biosystems, Inc. Methods for increasing the size of animals using needleless delivery constructs
US11046784B2 (en) 2006-03-31 2021-06-29 Chugai Seiyaku Kabushiki Kaisha Methods for controlling blood pharmacokinetics of antibodies
CN103272232B (zh) 2006-06-08 2018-07-24 中外制药株式会社 炎性疾病的预防或治疗药
US20090092660A1 (en) * 2006-08-09 2009-04-09 Trinity Biosystems, Inc. Methods and compositions for needleless delivery of particles
ES2687808T3 (es) 2007-09-26 2018-10-29 Chugai Seiyaku Kabushiki Kaisha Región constante de anticuerpo modificado
SI2202245T1 (sl) 2007-09-26 2016-10-28 Chugai Seiyaku Kabushiki Kaisha Postopek modificiranja izoelektrične točke protitelesa preko aminokislinske substitucije v CDR
EP2241332A4 (fr) 2007-12-05 2011-01-26 Chugai Pharmaceutical Co Ltd Agent thérapeutique contre le prurit
KR101643005B1 (ko) 2007-12-05 2016-07-28 추가이 세이야쿠 가부시키가이샤 항nr10 항체 및 그의 이용
PL2275443T3 (pl) 2008-04-11 2016-05-31 Chugai Pharmaceutical Co Ltd Cząsteczka wiążąca antygen zdolna do wiązania dwóch lub więcej cząsteczek antygenu w sposób powtarzalny
JP2011526591A (ja) 2008-06-30 2011-10-13 ノボ・ノルデイスク・エー/エス 抗ヒトインターロイキン−20抗体
JP2010210772A (ja) * 2009-03-13 2010-09-24 Dainippon Screen Mfg Co Ltd 液晶表示装置の製造方法
TWI544077B (zh) 2009-03-19 2016-08-01 Chugai Pharmaceutical Co Ltd Antibody constant region change body
JP5717624B2 (ja) 2009-03-19 2015-05-13 中外製薬株式会社 抗体定常領域改変体
US8454956B2 (en) 2009-08-31 2013-06-04 National Cheng Kung University Methods for treating rheumatoid arthritis and osteoporosis with anti-IL-20 antibodies
MX365235B (es) 2010-11-30 2019-05-28 Chugai Pharmaceutical Co Ltd Molécula de unión a antígeno capaz de unir repetidamente a la pluralidad de moléculas de antígeno.
DK2686347T3 (en) 2011-03-16 2018-06-25 Argenx Bvba Antibodies against CD70
CN104302780B (zh) * 2011-08-05 2017-04-12 艾克斯-马赛大学 纤维变性易感性il22ra2基因及其用途
US8597647B1 (en) * 2012-05-22 2013-12-03 National Cheng Kung University Humanized anti-IL-20 antibody and uses thereof
WO2014006230A1 (fr) * 2012-07-06 2014-01-09 Novo Nordisk A/S Epitopes d'il-20 et ligands d'il-20
US9221904B2 (en) 2012-07-19 2015-12-29 National Cheng Kung University Treatment of osteoarthritis using IL-20 antagonists
US8603470B1 (en) 2012-08-07 2013-12-10 National Cheng Kung University Use of IL-20 antagonists for treating liver diseases
US8852588B2 (en) 2012-08-07 2014-10-07 National Cheng Kung University Treating allergic airway disorders using anti-IL-20 receptor antibodies
AU2013310924B2 (en) * 2012-08-31 2017-08-03 Argenx Bvba Method for producing antibody molecules having inter-species, intra-target cross-reactivity
US10391168B1 (en) 2014-08-22 2019-08-27 University Of Bern Anti-CD70 combination therapy
RU2683020C2 (ru) * 2014-11-11 2019-03-26 Петр Иванович Никитин Субстанция и способ для модуляции активности агента в организме
MX2017013141A (es) 2015-04-14 2018-02-21 Chugai Pharmaceutical Co Ltd Composicion farmaceutica para la prevencion y/o tratamiento de dermatitis atopica que comprende antagonista de interleucina 31 (il-31) como ingrediente activo.
CN105601739B (zh) * 2016-02-22 2019-01-18 王晨辉 一种人源化抗白介素22基因工程抗体及其应用
WO2017202813A1 (fr) 2016-05-24 2017-11-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Procédés et compositions pharmaceutiques destinés au traitement d'infections pulmonaires bactériennes
GB201612337D0 (en) 2016-07-15 2016-08-31 Argen-X N V Ant-il-22r antibodies
JOP20190155A1 (ar) 2016-12-21 2019-06-23 Novartis Ag مترافقات عقار جسم مضاد لإزالة خلايا جذعية مكونة للدم
WO2020210816A1 (fr) * 2019-04-12 2020-10-15 Methodist Hospital Research Institute Particules thérapeutiques permettant à des cellules présentant un antigène d'attaquer des cellules cancéreuses
KR102517872B1 (ko) * 2019-06-12 2023-04-05 (주)아큐레시스바이오 암의 예방 또는 치료용 조성물
JP6845973B1 (ja) 2019-11-20 2021-03-24 中外製薬株式会社 抗体含有製剤

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
US4331647A (en) * 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
EP0154316B1 (fr) 1984-03-06 1989-09-13 Takeda Chemical Industries, Ltd. Lymphokine chimiquement modifiée et son procédé de préparation
NZ212437A (en) * 1985-06-17 1992-06-25 Mark Philip Best Site-directed antibody conjugates, and their preparation
WO1989004838A1 (fr) * 1987-11-25 1989-06-01 Immunex Corporation Recepteurs d'interleukine-1
US4847325A (en) 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
US5567584A (en) * 1988-01-22 1996-10-22 Zymogenetics, Inc. Methods of using biologically active dimerized polypeptide fusions to detect PDGF
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5116964A (en) 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
US5436155A (en) * 1991-12-31 1995-07-25 Arch Development Corporation Isolated DNA encoding a somatostatin receptor
US5789192A (en) 1992-12-10 1998-08-04 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
AU689214B2 (en) 1994-02-01 1998-03-26 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Fusion proteins that include antibody and nonantibody portions
WO2000077037A2 (fr) 1999-06-15 2000-12-21 Genentech, Inc. Polypeptides secretes et transmembranaires et acides nucleiques les codant
JP3713074B2 (ja) * 1995-08-30 2005-11-02 栄研化学株式会社 血清アミロイドaを認識するモノクローナル抗体
US5843697A (en) 1996-07-17 1998-12-01 University Of Medicine And Dentistry Of New Jersey Cells expressing IL-10 receptor and the CRFB4 gene product, an IL-10 receptor accessory protein
US5985614A (en) * 1996-08-30 1999-11-16 Human Genome Sciences, Inc. Polynucleotides encoding interleukin-19
US5945511A (en) 1997-02-20 1999-08-31 Zymogenetics, Inc. Class II cytokine receptor
US6133426A (en) * 1997-02-21 2000-10-17 Genentech, Inc. Humanized anti-IL-8 monoclonal antibodies
US6486301B1 (en) * 1997-07-16 2002-11-26 Human Genome Sciences, Inc. Interleukin-20
WO1999003982A1 (fr) 1997-07-16 1999-01-28 Human Genome Sciences, Inc. Interleukine-20
KR100236609B1 (ko) * 1997-08-01 2000-02-01 박호군 클로로하이드로실란 유도체 및 이의 제조방법
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
WO1999007740A2 (fr) 1997-08-06 1999-02-18 Zymogenetics, Inc. Homologues de lipocaline
US6551799B2 (en) * 1999-12-07 2003-04-22 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US6576743B1 (en) * 1997-11-26 2003-06-10 Zymogenetics, Inc. Mammalian cytokine-like polypeptide-10
EP1424393A3 (fr) 1997-11-26 2004-06-09 Zymogenetics Inc Polypeptides 10 du type cytokine de mammifère
WO1999037772A1 (fr) 1998-01-23 1999-07-29 Immunex Corporation Recepteurs de l'interleukine-18
EP1062332A2 (fr) 1998-03-09 2000-12-27 Schering Corporation Proteines receptrices humaines; reactifs et procedes associes
DK1490386T3 (da) 1998-03-10 2008-12-15 Genentech Inc Nyt polypeptid og nukleinsyrer kodende for dette
US6197582B1 (en) * 1998-03-18 2001-03-06 The Trustees Of Columbia University In The City Of New York Development of human monoclonal antibodies and uses thereof
US6982320B2 (en) 1998-03-19 2006-01-03 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
AU5203199A (en) 1998-05-26 1999-12-13 Procter & Gamble Company, The Chimeric molecules comprising an extracellular ligand binding domain of a receptor and an ige fc or constant region, and their use in an assay system
NZ510464A (en) 1998-09-01 2004-05-28 Genentech Inc Further pro polypeptides and sequences thereof
US6274710B1 (en) * 1998-10-26 2001-08-14 Ludwig Institute For Cancer Research Antibodies which specifically bind T Cell inducible factors (TIFs)
WO2000024758A1 (fr) 1998-10-26 2000-05-04 Ludwig Institute For Cancer Research Molecules d'acide nucleique isolees codant pour des facteurs inductibles derives de lymphocytes t (tif), proteines codees et leur utilisation
EP1141008A1 (fr) 1998-12-31 2001-10-10 Millennium Pharmaceuticals, Inc. Proteines ressemblant au recepteur de la cytokine de classe ii, et acides nucleiques les codant
BR0010097A (pt) 1999-04-28 2002-02-13 Genetics Inst Polinucleotìdeo isolado; célula hospedeira; processo para a produção de uma proteìna codificada pelo polinucleotìdeo; proteìna; composição; e; anticorpo
JP2002543840A (ja) 1999-05-19 2002-12-24 インサイト・ゲノミックス・インコーポレイテッド 細胞外シグナル伝達分子
WO2000073457A1 (fr) 1999-05-27 2000-12-07 Schering-Corporation Homologues mammaliens d'interleukine-10:il-d110 et il-d210
AU2883700A (en) 1999-06-23 2001-01-09 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
ES2286029T3 (es) 1999-07-07 2007-12-01 Zymogenetics Inc Receptor de citocina humano.
AU7573000A (en) 1999-09-01 2001-03-26 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2392109A1 (fr) 1999-11-18 2001-05-25 Schering Corporation Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant
ATE458814T1 (de) 1999-12-03 2010-03-15 Zymogenetics Inc Menschliches zytokinrezeptor
EP1857466B1 (fr) 1999-12-23 2010-10-20 ZymoGenetics, Inc. Récepteur d'interleukin-20
US6610286B2 (en) * 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
ATE339450T1 (de) * 1999-12-23 2006-10-15 Zymogenetics Inc Verfahren zur behandlung von entzündungen
CA2395369C (fr) 1999-12-23 2014-07-08 Zymogenetics, Inc. Cytokine zcyto18
NZ523122A (en) 2000-06-22 2004-06-25 Smithkline Beecham Corp Polypeptides and polynucleotides and methods of identifying agonists and antagonists in relation to treatment of diseases
JP2002015498A (ja) * 2000-06-29 2002-01-18 Fujitsu Ltd センス電流の設定方法
AU2001290524A1 (en) * 2000-08-08 2002-02-18 Zymogenetics Inc. Soluble zcytor 11 cytokine receptors
EP1315743B1 (fr) 2000-09-08 2012-11-07 Merck Sharp & Dohme Corp. Genes mammaliens, reactifs et methodes associes
ATE460429T1 (de) 2000-09-15 2010-03-15 Zymogenetics Inc Polypeptide enthaltend extrazellulären domäne von il-20ra und/oderr il-20rb
US7268223B2 (en) 2000-09-22 2007-09-11 Wyeth Isolated nucleic acid molecules which encode a soluble IL-TIF receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
US20030022827A1 (en) 2000-09-25 2003-01-30 Bertram Weiss Three new members of the cytokine receptor family class 2
MXPA03006218A (es) 2001-01-12 2004-09-13 Inst Genetics Llc Receptor de citosina tipo 2 y acidos nucleicos que codifican para lo mismo.
EP1390060A2 (fr) 2001-01-26 2004-02-25 Eli Lilly And Company Utilisation de lp82 pour traiter les problemes de poids
BR0207528A (pt) 2001-02-23 2006-01-17 Inst Genetics Llc Anticorpo, composição farmacêutica, e, usos de uma quantidade efetiva de um agente, de uma quantidade terapeuticamente efetiva de um anticorpo para il-22, de uma quantidade imunogênica do antìgeno e uma quantidade aumentadora de imunogenicidade de il-22 em combinação, de uma quantidade efetiva do anticorpo ou fragmento do mesmo e de uma quantidade suficiente de anticorpo ou fragmento ligado a antìgeno do mesmo
WO2002070001A2 (fr) 2001-02-28 2002-09-12 Eli Lilly And Company Utilisation de lp82 pour traiter les troubles hematopoietiques
CA2439636A1 (fr) 2001-03-02 2002-09-12 Zymogenetics, Inc. Recepteur de cytokine murin
CA2440596C (fr) * 2001-03-09 2011-05-24 Zymogenetics, Inc. Recepteur de cytokine heterodimere soluble
US20030099608A1 (en) 2001-03-27 2003-05-29 Presnell Scott R. Human cytokine receptor
EP2163256B1 (fr) * 2001-05-11 2015-09-02 Ludwig Institute for Cancer Research Ltd. Protéines à liaison spécifique et leurs utilisations
EP1439850A4 (fr) 2001-10-22 2006-05-03 Lilly Co Eli Proteines solubles inhibant les voies de transduction du signal de la cytokine
DE10154579A1 (de) 2001-11-07 2003-05-28 Medigene Ag Topikale Verwendung von Cytokinen und Chemokinen zur Behandlung von viralen oder mykotischen Hauterkrankungen oder Tumorerkrankungen
JP4532902B2 (ja) 2001-12-17 2010-08-25 ザイモジェネティクス,インコーポレイティド 子宮頸部癌の治療方法
US20040236075A1 (en) 2002-07-24 2004-11-25 Laure Dumoutier Novel glass II cytokine receptors, and uses thereof
EA009026B1 (ru) 2003-03-24 2007-10-26 Займоджинетикс, Инк. Антитела против il-22ra, их партнеры по связыванию и способы их применения при воспалениях
CN1798768B (zh) * 2003-03-24 2013-05-08 津莫吉尼蒂克斯公司 抗il-22ra抗体和结合伴侣及其应用
EP1692180B1 (fr) 2003-11-21 2009-11-04 ZymoGenetics, Inc. Anticorps et partenaires de liaison anti-il 20 et procedes d'utilisation dans l'inflammation
EP1812476B1 (fr) * 2004-10-22 2010-07-21 ZymoGenetics, Inc. Anticorps anti-il-22ra et partenaires de liaison et methodes d'utilisation de ces anticorps et de ces partenaires de liaison pour le traitement de maladies inflammatoires

Also Published As

Publication number Publication date
WO2004085476A2 (fr) 2004-10-07
MXPA05010134A (es) 2005-11-16
AU2004223836A2 (en) 2004-10-07
BRPI0408683A (pt) 2006-03-28
US20060134756A1 (en) 2006-06-22
WO2004085476A3 (fr) 2005-03-31
KR20050116390A (ko) 2005-12-12
ATE475673T1 (de) 2010-08-15
US20100111948A1 (en) 2010-05-06
WO2004085475A3 (fr) 2005-07-14
KR20050116392A (ko) 2005-12-12
EA009026B1 (ru) 2007-10-26
US20090074661A1 (en) 2009-03-19
US20080233115A1 (en) 2008-09-25
DE602004028347D1 (de) 2010-09-09
BRPI0408705A (pt) 2006-03-07
CA2519089A1 (fr) 2004-10-07
EA009124B1 (ru) 2007-10-26
JP2007525438A (ja) 2007-09-06
US8163286B2 (en) 2012-04-24
US20120207761A1 (en) 2012-08-16
EP1606317A2 (fr) 2005-12-21
CN103864934A (zh) 2014-06-18
CA2519089C (fr) 2014-12-23
AU2004223837A2 (en) 2004-10-07
AU2004223836A1 (en) 2004-10-07
AU2004223837A1 (en) 2004-10-07
ES2347657T3 (es) 2010-11-03
US20040209330A1 (en) 2004-10-21
CN102690350A (zh) 2012-09-26
EP1606316A2 (fr) 2005-12-21
MXPA05010136A (es) 2005-11-16
KR20110091598A (ko) 2011-08-11
CA2519057A1 (fr) 2004-10-07
AU2004223837B2 (en) 2011-04-21
EA200501505A1 (ru) 2006-06-30
EA200501506A1 (ru) 2006-06-30
AU2004223837C1 (en) 2012-03-15
NO20054892D0 (no) 2005-10-21
WO2004085475A2 (fr) 2004-10-07
DK1606317T3 (da) 2010-10-25
EP1606317B1 (fr) 2010-07-28
JP2007525437A (ja) 2007-09-06

Similar Documents

Publication Publication Date Title
NO20054892D0 (no) Anti-IL-22RA-antistoffer og bindingspartnere og fremgangsmater for anvendelse ved inflammasjon
NO20072602L (no) Anti-IL-22RA-antistoffer og bindingspartnere og fremgangsmater for anvendelse ved inflammasjon
MXPA06014465A (es) Zcytor14 soluble, anticuerpos anti-zcytor14 y moleculas de union y metodos de uso en inflamacion.
WO2006086396A3 (fr) Anticorps et partenaires de liaison anti-il-20, anti-il-22 et anti-il-22ra, et methodes d'utilisation de ces anticorps et partenaires de liaison dans des processus inflammatoires
WO2005052000A3 (fr) Anticorps et partenaires de liaison anti-il 20 et procedes d'utilisation dans l'inflammation
EA200800956A1 (ru) Антагонисты il-17a и il-17f и способы их использования
WO2008039553A8 (fr) Il-17rcx4 soluble et procédés d'utilisation dans l'inflammation
DK1553975T3 (da) Optimerede Fc-varianter og fremgangsmåder til generering heraf.
DK1368060T3 (da) HMGB1-proteininhibitorer og/eller antagonister til behandlingen af vaskulære sygdomme
NO20044658L (no) Anvendelse av osteoprotegerin til behandling og/eller forhindring av fibrotiske sykdommer
EA200700823A1 (ru) Растворимый zcytor21, анти-zcytor21 антитела и связывающие партнёры и способы применения при воспалении
RS20060023A (en) Use of soluble cd164 in inflammatory and/or autoimmune disorders
EA200600956A1 (ru) Молекулы-антагонисты цитокинов
EA200500624A1 (ru) Промотор для il-18bp, его получение и применение
DE60209797D1 (de) Antikörper zur stimulierung der produktion von il-1ra

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application