EA200700823A1 - Растворимый zcytor21, анти-zcytor21 антитела и связывающие партнёры и способы применения при воспалении - Google Patents

Растворимый zcytor21, анти-zcytor21 антитела и связывающие партнёры и способы применения при воспалении

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Publication number
EA200700823A1
EA200700823A1 EA200700823A EA200700823A EA200700823A1 EA 200700823 A1 EA200700823 A1 EA 200700823A1 EA 200700823 A EA200700823 A EA 200700823A EA 200700823 A EA200700823 A EA 200700823A EA 200700823 A1 EA200700823 A1 EA 200700823A1
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EA
Eurasian Patent Office
Prior art keywords
zcytor21
antibodies
binding partners
methods
soluble
Prior art date
Application number
EA200700823A
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English (en)
Inventor
Зирен Гао
Ролф И. Кустнер
Марк У. Эпплби
Кэтерин И. Луис
Патрисия А. Маккернан
Шеннон Л. Окада
Дейвид У. Тэфт
Джозеф Л. Куйджпер
Стивен Р. Джесперс
Стивен Д. Левин
Original Assignee
Займодженетикс, Инк., Сша
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Займодженетикс, Инк., Сша filed Critical Займодженетикс, Инк., Сша
Publication of EA200700823A1 publication Critical patent/EA200700823A1/ru

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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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Abstract

Изобретение относится к антагонистам ZcytoR21, таким как растворимые рецепторы и анти-ZcytoR21 антитела, которые являются пригодными для блокирования, ингибирования, снижения, противодействия или нейтрализации активности IL-17C. IL-17C является цитокином, который вовлечен в воспалительные процессы и заболевания человека. ZcytoR21 является рецептором IL-17C. Изобретение включает в себя растворимый ZcytoR21, анти-ZcytoR21 антитела и связывающие партнеры, а также способы противодействия IL-17C с помощью таких растворимых рецепторов, антител и связывающих партнеров.
EA200700823A 2004-10-18 2005-10-18 Растворимый zcytor21, анти-zcytor21 антитела и связывающие партнёры и способы применения при воспалении EA200700823A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61965104P 2004-10-18 2004-10-18
US62220704P 2004-10-25 2004-10-25
PCT/US2005/037332 WO2006044840A2 (en) 2004-10-18 2005-10-18 Soluble zcytor21, anti-zcytor21 antibodies and binding partners and methods of using in inflammation

Publications (1)

Publication Number Publication Date
EA200700823A1 true EA200700823A1 (ru) 2008-02-28

Family

ID=36090952

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700823A EA200700823A1 (ru) 2004-10-18 2005-10-18 Растворимый zcytor21, анти-zcytor21 антитела и связывающие партнёры и способы применения при воспалении

Country Status (12)

Country Link
US (3) US20060142192A1 (ru)
EP (1) EP1802657A2 (ru)
JP (1) JP2008516985A (ru)
KR (1) KR20070084330A (ru)
AU (1) AU2005295421A1 (ru)
BR (1) BRPI0516603A (ru)
CA (1) CA2584078A1 (ru)
EA (1) EA200700823A1 (ru)
IL (1) IL182186A0 (ru)
MX (1) MX2007004597A (ru)
NO (1) NO20072514L (ru)
WO (1) WO2006044840A2 (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040197306A1 (en) * 2000-05-24 2004-10-07 Gorman Daniel M. Mammalian receptor proteins; related reagents and methods
BRPI0516603A (pt) * 2004-10-18 2008-09-16 Zymogenetics Inc receptor solúvel isolado, anticorpo ou fragmento de anticorpo, e, métodos para tratar uma doença imuno-mediada em um paciente em necessidade de tal tratamento, para reduzir a inflamação mediada pela il-17c, para tratar um mamìfero afligido com uma doença inflamatória, e para tratar uma condição patológica em um paciente associada com a atividade de zcytor21
WO2007047738A1 (en) * 2005-10-18 2007-04-26 Zymogenetics, Inc. Il-17c antagonists and methods of using the same
WO2008049070A2 (en) * 2006-10-18 2008-04-24 Zymogenetics, Inc. Il-17c antagonists and methods of using the same
AU2012324895B2 (en) 2011-10-19 2017-03-16 Galapagos Nv Antagonists of IL17C for the treatment of inflammatory disorders
EP3359161A1 (en) * 2015-10-05 2018-08-15 MorphoSys AG Antagonists of il-17c for the treatment and/or prevention of atopic dermatitis
CU20180087A7 (es) 2016-02-19 2019-03-04 Galapagos Nv Anticuerpos para il-17-c
IL309179A (en) * 2021-06-10 2024-02-01 Janssen Biotech Inc Nucleic acid coding for KLK2-GPI fusion protein, recombinant cells and their uses

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2215394C (en) * 1995-03-23 2011-04-26 Immunex Corporation Il-17 receptor
US6579520B2 (en) * 1998-05-15 2003-06-17 Genentech, Inc. IL-17 related mammalian cytokine polypeptides (IL-17E)
US20020177188A1 (en) * 1998-05-15 2002-11-28 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
US6569645B2 (en) * 1999-05-14 2003-05-27 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
MXPA02011617A (es) * 2000-05-24 2003-03-10 Schering Corp Proteinas de mamiferos receptoras, reactivosy metodos relacionados.
US20040197306A1 (en) * 2000-05-24 2004-10-07 Gorman Daniel M. Mammalian receptor proteins; related reagents and methods
US20030096969A1 (en) * 2000-06-02 2003-05-22 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2005508615A (ja) * 2001-07-09 2005-04-07 ザイモジェネティクス，インコーポレイティド ヒトサイトカイン受容体
BRPI0516603A (pt) * 2004-10-18 2008-09-16 Zymogenetics Inc receptor solúvel isolado, anticorpo ou fragmento de anticorpo, e, métodos para tratar uma doença imuno-mediada em um paciente em necessidade de tal tratamento, para reduzir a inflamação mediada pela il-17c, para tratar um mamìfero afligido com uma doença inflamatória, e para tratar uma condição patológica em um paciente associada com a atividade de zcytor21
WO2007047738A1 (en) * 2005-10-18 2007-04-26 Zymogenetics, Inc. Il-17c antagonists and methods of using the same

Also Published As

Publication number Publication date
CA2584078A1 (en) 2006-04-27
MX2007004597A (es) 2007-06-22
US20070049524A1 (en) 2007-03-01
EP1802657A2 (en) 2007-07-04
BRPI0516603A (pt) 2008-09-16
US20060142192A1 (en) 2006-06-29
WO2006044840A2 (en) 2006-04-27
WO2006044840A3 (en) 2006-10-26
AU2005295421A1 (en) 2006-04-27
IL182186A0 (en) 2007-07-24
NO20072514L (no) 2007-07-17
WO2006044840A8 (en) 2006-07-06
JP2008516985A (ja) 2008-05-22
US20070049525A1 (en) 2007-03-01
KR20070084330A (ko) 2007-08-24

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