CA2392109A1 - Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant - Google Patents

Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant Download PDF

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Publication number
CA2392109A1
CA2392109A1 CA002392109A CA2392109A CA2392109A1 CA 2392109 A1 CA2392109 A1 CA 2392109A1 CA 002392109 A CA002392109 A CA 002392109A CA 2392109 A CA2392109 A CA 2392109A CA 2392109 A1 CA2392109 A1 CA 2392109A1
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CA
Canada
Prior art keywords
ser
leu
pro
glu
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002392109A
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English (en)
Inventor
Daniel M. Gorman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2392109A1 publication Critical patent/CA2392109A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des acides nucléiques codant des récepteurs mammaliens, notamment de primates, des protéines de récepteurs purifiées, et certains de leurs fragments. L'invention concerne également des anticorps, aussi bien polyclonaux que monoclonaux. L'invention concerne enfin des modes d'utilisation de ces compositions à des fins tant de diagnostics que thérapeutiques.
CA002392109A 1999-11-18 2000-11-16 Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant Abandoned CA2392109A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US44306099A 1999-11-18 1999-11-18
US09/443,060 1999-11-18
US17032099P 1999-12-13 1999-12-13
US60/170,320 1999-12-13
PCT/US2000/031363 WO2001036467A2 (fr) 1999-11-18 2000-11-16 Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant

Publications (1)

Publication Number Publication Date
CA2392109A1 true CA2392109A1 (fr) 2001-05-25

Family

ID=26865975

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002392109A Abandoned CA2392109A1 (fr) 1999-11-18 2000-11-16 Proteines de recepteurs mammaliens, reactifs et procedes s'y rapportant

Country Status (6)

Country Link
EP (1) EP1230368A2 (fr)
JP (1) JP2003523179A (fr)
AU (1) AU1919201A (fr)
CA (1) CA2392109A1 (fr)
MX (1) MXPA02005058A (fr)
WO (1) WO2001036467A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7198789B2 (en) 1998-03-17 2007-04-03 Genetics Institute, Llc Methods and compositions for modulating interleukin-21 receptor activity
US6057128A (en) 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
JP2003534773A (ja) 1999-12-03 2003-11-25 ザイモジェネティクス,インコーポレイティド ヒトサイトカイン受容体
US20030170823A1 (en) 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
ES2381650T3 (es) 2000-08-08 2012-05-30 Zymogenetics, Inc. Receptores de citoquinas Zcytor11 solubles
US7268223B2 (en) 2000-09-22 2007-09-11 Wyeth Isolated nucleic acid molecules which encode a soluble IL-TIF receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
US7094570B2 (en) 2003-03-11 2006-08-22 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode a soluble IL-TIF/IL-22 receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
EP1191035A3 (fr) * 2000-09-25 2002-04-17 Schering Aktiengesellschaft Trois membres de la famille des recepteurs de la cytokine de classe II
US7176180B2 (en) 2001-01-12 2007-02-13 Wyeth Type 2 cytokine receptor and nucleic acids encoding same
WO2002070655A2 (fr) * 2001-03-02 2002-09-12 Zymogenetics, Inc. Recepteur de cytokine murin
CA2439961A1 (fr) 2001-03-27 2002-10-03 Zymogenetics, Inc. Recepteur de cytokine humaine
CA2480163A1 (fr) 2002-03-22 2003-10-09 Zymogenetics, Inc. Anticorps anti-il-tif et leurs methodes d'utilisation dans une inflammation
GB0216661D0 (en) * 2002-07-17 2002-08-28 Ares Trading Sa Protein
CN1777621A (zh) 2003-03-14 2006-05-24 Wyeth公司 抗人il-21受体的抗体及其应用
KR20110091598A (ko) 2003-03-24 2011-08-11 지모제넥틱스, 인코포레이티드 항-il-22ra 항체 및 결합 파트너 및 염증에 있어서의 사용 방법
PT1812476E (pt) 2004-10-22 2010-11-08 Zymogenetics Inc Anticorpos anti-il-22ra e parceiros de ligação e métodos de utilização no tratamento de inflamações
AU2006342792A1 (en) 2005-12-02 2007-11-08 Genentech, Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to IL-22 and IL-22R
US12012441B2 (en) 2020-10-26 2024-06-18 Neptune Biosciences Llc Engineered human IL-21 cytokines and methods for using the same
WO2023187201A1 (fr) * 2022-04-01 2023-10-05 Universite Catholique De Louvain Fragments du récepteur de la thrombopoïétine et leurs utilisations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198359A (en) * 1989-03-07 1993-03-30 Boehringer Ingelheim International Gmbh Recombinant protein receptor for il-2
US5945511A (en) * 1997-02-20 1999-08-31 Zymogenetics, Inc. Class II cytokine receptor
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
AU2661199A (en) * 1998-02-06 1999-08-23 Schering Corporation Mammalian receptor proteins; related reagents and methods
AU5104799A (en) * 1998-08-04 2000-02-28 Regeneron Pharmaceuticals, Inc. Novel orphan cytokine receptors
EP1124851A1 (fr) * 1998-11-06 2001-08-22 Smithkline Beecham Corporation Hnovilr
AU5142300A (en) * 1999-05-18 2000-12-05 Millennium Pharmaceuticals, Inc. Il-9/il-2 receptor-like molecules and uses thereof
JP2003534773A (ja) * 1999-12-03 2003-11-25 ザイモジェネティクス,インコーポレイティド ヒトサイトカイン受容体
CA2395369C (fr) * 1999-12-23 2014-07-08 Zymogenetics, Inc. Cytokine zcyto18

Also Published As

Publication number Publication date
JP2003523179A (ja) 2003-08-05
AU1919201A (en) 2001-05-30
MXPA02005058A (es) 2002-11-07
EP1230368A2 (fr) 2002-08-14
WO2001036467A2 (fr) 2001-05-25
WO2001036467A3 (fr) 2002-05-10

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead