NO20052988L - Farmakologisk vitreolyse. - Google Patents

Farmakologisk vitreolyse.

Info

Publication number
NO20052988L
NO20052988L NO20052988A NO20052988A NO20052988L NO 20052988 L NO20052988 L NO 20052988L NO 20052988 A NO20052988 A NO 20052988A NO 20052988 A NO20052988 A NO 20052988A NO 20052988 L NO20052988 L NO 20052988L
Authority
NO
Norway
Prior art keywords
eye
vitreous
reduction
plasmin
disorder
Prior art date
Application number
NO20052988A
Other languages
English (en)
Other versions
NO333837B1 (no
NO20052988D0 (no
Inventor
Steve Pakola
Marc De Smet
Original Assignee
Thromb X Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9949140&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20052988(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Thromb X Nv filed Critical Thromb X Nv
Publication of NO20052988D0 publication Critical patent/NO20052988D0/no
Publication of NO20052988L publication Critical patent/NO20052988L/no
Publication of NO333837B1 publication Critical patent/NO333837B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01035—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24007—Interstitial collagenase (3.4.24.7), i.e. matrix metalloprotease 1 or MMP1
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/02—Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02004—Chondroitin ABC lyase (4.2.2.4), i.e. chondroitinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/02—Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02005—Chondroitin AC lyase (4.2.2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/02—Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02019—Chondroitin B lyase (4.2.2.19)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Insulating Materials (AREA)

Abstract

2005-09-05 Sammendrag Fremgangsmåte for behandling eller forebygging av en forstyrrelse, eller en komplikasjon ved en forstyrrelse, i et øye hos et individ, omfattende at et glasslegeme og/eller en vandig væske bringes i kontakt med et preparat omfattende en trunkert form av plasmin omfattende et katalytisk domene av plasmin (TPCD). TPCD innbefatter, men er ikke begrenset til, miniplasmin, mikroplasmin og derivater og varianter derav. Fremgangsmåtene ifølge oppfinnelsen kan anvendes til redusering av viskositeten av glasslegemet, flytendegjøring av glasslegemet, indusering av Iøsning av bakre glasslegeme, redusering av hemoragisk blod fra øyet, fjerning eller redusering av materialer som er toksiske for øyet, fjerning eller redusering av intraokulære fremmede substanser fra øyet, øking av diffusjon av et preparat administrert til et øye, redusering av ekstraretinal neovaskularisering, og hvilke som helst kombinasjoner derav. Fremgangsmåten kan anvendes i fravær av, eller som et supplement til, vitrektomi.
NO20052988A 2002-12-06 2005-06-17 Anvendelse av en sammensetning som omfatter et trunkert plasminprotein for fremstilling av et medikament for behandling av en lidelse i et øye samt sammensetning og sett. NO333837B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0228409.9A GB0228409D0 (en) 2002-12-06 2002-12-06 Pharmacological vitreolysis
PCT/US2003/038714 WO2004052228A2 (en) 2002-12-06 2003-12-05 Pharmacological vitreolysis

Publications (3)

Publication Number Publication Date
NO20052988D0 NO20052988D0 (no) 2005-06-17
NO20052988L true NO20052988L (no) 2005-09-05
NO333837B1 NO333837B1 (no) 2013-09-30

Family

ID=9949140

Family Applications (4)

Application Number Title Priority Date Filing Date
NO20052988A NO333837B1 (no) 2002-12-06 2005-06-17 Anvendelse av en sammensetning som omfatter et trunkert plasminprotein for fremstilling av et medikament for behandling av en lidelse i et øye samt sammensetning og sett.
NO20121169A NO343759B1 (no) 2002-12-06 2012-10-12 Første preparat omfattende et trunkert plasminprotein (TPCD) omfattende en katalytisk domene av plasmin og et andre preparat omfattende et ytterligere middel for anvendelse, samt sett.
NO20121170A NO20121170A1 (no) 2002-12-06 2012-10-12 Farmakologisk vitreolyse
NO2013016C NO2013016I2 (no) 2002-12-06 2013-11-19 Okriplasmin

Family Applications After (3)

Application Number Title Priority Date Filing Date
NO20121169A NO343759B1 (no) 2002-12-06 2012-10-12 Første preparat omfattende et trunkert plasminprotein (TPCD) omfattende en katalytisk domene av plasmin og et andre preparat omfattende et ytterligere middel for anvendelse, samt sett.
NO20121170A NO20121170A1 (no) 2002-12-06 2012-10-12 Farmakologisk vitreolyse
NO2013016C NO2013016I2 (no) 2002-12-06 2013-11-19 Okriplasmin

Country Status (24)

Country Link
US (11) US7547435B2 (no)
EP (3) EP1581254B1 (no)
JP (4) JP5426063B2 (no)
CN (1) CN100577202C (no)
AT (1) ATE534400T1 (no)
AU (1) AU2003300821C1 (no)
BE (1) BE2013C055I2 (no)
BR (2) BR0317033A (no)
CA (1) CA2508606C (no)
CY (2) CY1112561T1 (no)
DK (1) DK1581254T3 (no)
ES (2) ES2731625T3 (no)
FR (1) FR13C0052I2 (no)
GB (1) GB0228409D0 (no)
HU (1) HUS1300040I1 (no)
IL (3) IL169008A (no)
LU (1) LU92273I2 (no)
MX (1) MXPA05006038A (no)
NO (4) NO333837B1 (no)
NZ (1) NZ541075A (no)
PT (2) PT2327416T (no)
SI (1) SI1581254T1 (no)
WO (1) WO2004052228A2 (no)
ZA (1) ZA200505193B (no)

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