NO20052568L - Fremgangsmate for fremstilling av makrolidforbindelse - Google Patents
Fremgangsmate for fremstilling av makrolidforbindelseInfo
- Publication number
- NO20052568L NO20052568L NO20052568A NO20052568A NO20052568L NO 20052568 L NO20052568 L NO 20052568L NO 20052568 A NO20052568 A NO 20052568A NO 20052568 A NO20052568 A NO 20052568A NO 20052568 L NO20052568 L NO 20052568L
- Authority
- NO
- Norway
- Prior art keywords
- compound
- macrolide compound
- streptomyces
- represented
- formula
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 239000003120 macrolide antibiotic agent Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- 241001134635 Micromonosporaceae Species 0.000 abstract 1
- 241000235575 Mortierella Species 0.000 abstract 1
- 241000187747 Streptomyces Species 0.000 abstract 1
- 241000187180 Streptomyces sp. Species 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 210000004748 cultured cell Anatomy 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
- C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002346796 | 2002-11-29 | ||
| PCT/JP2003/015170 WO2004050890A1 (ja) | 2002-11-29 | 2003-11-27 | マクロライド系化合物の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20052568D0 NO20052568D0 (no) | 2005-05-27 |
| NO20052568L true NO20052568L (no) | 2005-06-29 |
Family
ID=32462862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20052568A NO20052568L (no) | 2002-11-29 | 2005-05-27 | Fremgangsmate for fremstilling av makrolidforbindelse |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7745198B2 (pt) |
| EP (1) | EP1580278A4 (pt) |
| JP (1) | JP4439401B2 (pt) |
| KR (1) | KR20050086873A (pt) |
| CN (1) | CN1717493A (pt) |
| AU (1) | AU2003284469B2 (pt) |
| BR (1) | BR0316746A (pt) |
| CA (1) | CA2507641A1 (pt) |
| MX (1) | MXPA05005672A (pt) |
| NO (1) | NO20052568L (pt) |
| NZ (1) | NZ540103A (pt) |
| RU (1) | RU2330069C2 (pt) |
| WO (1) | WO2004050890A1 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI334866B (en) * | 2002-05-29 | 2010-12-21 | Mercian Corp | Novel physiologically active substances |
| KR20060110865A (ko) * | 2003-11-27 | 2006-10-25 | 에자이 가부시키가이샤 | 매크로라이드계 화합물의 수산화에 관여하는 ｄｎａ |
| KR100834488B1 (ko) * | 2004-07-20 | 2008-06-09 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 플라디에놀라이드의 생합성에 관여하는 폴리펩티드를코딩하는 ｄｎａ |
| TW200716744A (en) * | 2005-05-26 | 2007-05-01 | Eisai R&D Man Co Ltd | Genetically modified microorganism and process for production of macrolide compound using the microorganism |
| EP1935893A4 (en) * | 2005-10-13 | 2009-07-22 | Eisai R&D Man Co Ltd | TOTAL SYNTHESIS OF PLADIENOLIDE B AND PLADIENOLIDE D |
| EP2052723A4 (en) * | 2006-08-14 | 2010-07-28 | Eisai R&D Man Co Ltd | STABLE LYOPHILIZED PREPARATION |
| MX2009008068A (es) * | 2007-01-29 | 2009-11-18 | Eisai R&D Man Co Ltd | Compuesto macrolido en forma solida, proceso para su preparacion y composicion farmaceutica que lo contiene. |
| CA3130061C (en) * | 2013-04-04 | 2024-05-28 | President And Fellows Of Harvard College | Macrolides and methods of their preparation and use |
| UA119458C2 (uk) | 2014-05-15 | 2019-06-25 | Ейсей Р Енд Д Менеджмент Ко., Лтд. | Сполуки піридину пладієноліду та способи застосування |
| EP3211997A4 (en) | 2014-10-08 | 2018-10-24 | President and Fellows of Harvard College | 14-membered ketolides and methods of their preparation and use |
| CA2980315A1 (en) | 2015-03-25 | 2016-09-29 | President And Fellows Of Harvard College | Macrolides with modified desosamine sugars and uses thereof |
| EP3344780B1 (en) | 2015-09-01 | 2021-06-23 | Eisai R&D Management Co., Ltd. | Splice variants associated with neomorphic sf3b1 mutants |
| CN108473479B (zh) | 2015-11-18 | 2024-05-07 | 卫材研究发展管理有限公司 | 普拉二烯内酯吡啶化合物的固态形式和使用方法 |
| US20200190593A1 (en) | 2017-03-15 | 2020-06-18 | Eisai R&D Management Co., Ltd. | Spliceosome mutations and uses thereof |
| BR112020008362A2 (pt) | 2017-10-31 | 2020-11-03 | Eisai R&D Management Co., Ltd. | composição farmacêutica, combinação, uso de uma combinação, e, método para tratar câncer. |
| IL303335A (en) | 2018-04-09 | 2023-07-01 | Eisai R&D Man Co Ltd | Palladianolide compounds and their use |
| TWI834655B (zh) | 2018-04-12 | 2024-03-11 | 日商衛材R&D企管股份有限公司 | 特定芳基普拉二烯內酯化合物及其使用方法 |
| CA3101205A1 (en) | 2018-06-01 | 2019-12-05 | Eisai R&D Management Co., Ltd. | Methods of using splicing modulators |
| TW202233187A (zh) | 2020-11-04 | 2022-09-01 | 日商衛材R&D企管股份有限公司 | 骨髓發育不良症候群（ｍｄｓ）之生物標記物及其使用方法 |
| CN114478257A (zh) * | 2021-12-29 | 2022-05-13 | 福建省山河药业有限公司 | 一种抗肿瘤霉菌酸类化合物及其制备方法、应用 |
| WO2023131866A1 (en) | 2022-01-05 | 2023-07-13 | Eisai R&D Management Co., Ltd. | Biomarkers for myelodysplastic syndrome (mds) and methods of using the same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04352783A (ja) * | 1991-05-27 | 1992-12-07 | Taisho Pharmaceut Co Ltd | １２員環マクロライド系化合物 |
| EP1192147A1 (en) | 1999-06-03 | 2002-04-03 | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Mycolactone and related compounds, compositions and methods of use |
| US6562602B2 (en) | 2000-08-03 | 2003-05-13 | Kosan Biosciences, Inc. | Fermentation and purification of mycolactones |
| TWI312681B (en) * | 2001-02-01 | 2009-08-01 | Novel physiologically active substance | |
| TWI233361B (en) | 2001-04-13 | 2005-06-01 | Gen Hospital Corp | Methods of preventing UVB-induced skin damage |
| TWI334866B (en) | 2002-05-29 | 2010-12-21 | Mercian Corp | Novel physiologically active substances |
| RU2338741C2 (ru) * | 2002-07-31 | 2008-11-20 | Мершан Корпорейшн | Новые физиологически активные вещества |
| EP1935893A4 (en) | 2005-10-13 | 2009-07-22 | Eisai R&D Man Co Ltd | TOTAL SYNTHESIS OF PLADIENOLIDE B AND PLADIENOLIDE D |
-
2003
- 2003-11-27 BR BR0316746-1A patent/BR0316746A/pt not_active IP Right Cessation
- 2003-11-27 RU RU2005120390/13A patent/RU2330069C2/ru not_active IP Right Cessation
- 2003-11-27 CA CA002507641A patent/CA2507641A1/en not_active Abandoned
- 2003-11-27 AU AU2003284469A patent/AU2003284469B2/en not_active Ceased
- 2003-11-27 JP JP2004556846A patent/JP4439401B2/ja not_active Expired - Fee Related
- 2003-11-27 WO PCT/JP2003/015170 patent/WO2004050890A1/ja active Application Filing
- 2003-11-27 EP EP03775924A patent/EP1580278A4/en not_active Withdrawn
- 2003-11-27 KR KR1020057009524A patent/KR20050086873A/ko not_active Application Discontinuation
- 2003-11-27 NZ NZ540103A patent/NZ540103A/en unknown
- 2003-11-27 MX MXPA05005672A patent/MXPA05005672A/es active IP Right Grant
- 2003-11-27 US US10/532,412 patent/US7745198B2/en not_active Expired - Fee Related
- 2003-11-27 CN CNA2003801044327A patent/CN1717493A/zh active Pending
-
2005
- 2005-05-27 NO NO20052568A patent/NO20052568L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050086873A (ko) | 2005-08-30 |
| JP4439401B2 (ja) | 2010-03-24 |
| EP1580278A1 (en) | 2005-09-28 |
| AU2003284469A1 (en) | 2004-06-23 |
| CN1717493A (zh) | 2006-01-04 |
| AU2003284469B2 (en) | 2008-02-21 |
| JPWO2004050890A1 (ja) | 2006-03-30 |
| US7745198B2 (en) | 2010-06-29 |
| EP1580278A4 (en) | 2010-08-25 |
| WO2004050890A1 (ja) | 2004-06-17 |
| MXPA05005672A (es) | 2005-08-16 |
| BR0316746A (pt) | 2005-10-18 |
| RU2005120390A (ru) | 2006-01-27 |
| US20060141589A1 (en) | 2006-06-29 |
| CA2507641A1 (en) | 2004-06-17 |
| NO20052568D0 (no) | 2005-05-27 |
| RU2330069C2 (ru) | 2008-07-27 |
| NZ540103A (en) | 2007-05-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20052568L (no) | Fremgangsmate for fremstilling av makrolidforbindelse | |
| Zheng et al. | E ndomicrobium proavitum, the first isolate of E ndomicrobia class. nov.(phylum E lusimicrobia)–an ultramicrobacterium with an unusual cell cycle that fixes nitrogen with a G roup IV nitrogenase | |
| Hur et al. | Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein | |
| Riedlinger et al. | Auxofuran, a novel metabolite that stimulates the growth of fly agaric, is produced by the mycorrhiza helper bacterium Streptomyces strain AcH 505 | |
| Gustafson et al. | The macrolactins, a novel class of antiviral and cytotoxic macrolides from a deep-sea marine bacterium | |
| KR101021234B1 (ko) | 미생물에 의한 비타민 ｃ의 생성 방법 | |
| Ladapo et al. | Method for isolation of auxotrophs in the methanogenic archaebacteria: role of the acetyl-CoA pathway of autotrophic CO2 fixation in Methanococcus maripaludis. | |
| Chen et al. | Epigenetic modifier-induced biosynthesis of novel fusaric acid derivatives in endophytic fungi from Datura stramonium L. | |
| DK149080B (da) | Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre | |
| Nakata | Organic nutrients required for growth and sporulation of Bacillus cereus | |
| NO991863L (no) | Nye bakteriestammer og bruken derav i fermenteringsprosesser for 2-keto-L-gulonsyreproduksjon | |
| BRPI0208535B8 (pt) | método para a produção de lipopolissacarídeo que pode gerar 3-o-4-monofosforil desacilado lipídeo a | |
| NO20075911L (no) | Genetisk modifisert mikroorganisme og fremgangsmate for fremstilling av makrolidforbindelser ved anvendelse av mikroorganismen | |
| DK1711593T3 (da) | Fremgangsm de til fremstilling af L-aminosyrer ved anvendelse af stammer fra familien Enterobacteriaceae | |
| King et al. | Characterization of new thaxtomin A analogues generated in vitro by Streptomyces scabies | |
| NO20070802L (no) | Gener som koder for forgrent-kjede alfa-ketosyre-dehydrogenase-kompleks fra Streptomyces avermitilis. | |
| DK1216237T3 (da) | Proces til fremstilling af mycophenolsyre og derivater deraf | |
| Limtong et al. | Effect of acetic acid on growth and ethanol fermentation of xylose fermenting yeast and Saccharomyces cerevisiae | |
| JPH1045747A (ja) | アンチマイシンａ系化合物の混合物 | |
| US2917435A (en) | Preparation of 2-keto-1-gulonic acid by pseudomonas aeruginosa | |
| Kizuka et al. | Studies on actinomycetes isolated from plant leaves | |
| MX2007008155A (es) | Metodo para producir compuestos derivados probioticamente. | |
| Petrescu et al. | A yeast strain that uses D-galacturonic acid as a substrate for L-ascorbic acid biosynthesis | |
| NO944197L (no) | Moenomycin-avspaltningsprodukter med hydroksylert og oksydert lipidsidekjede | |
| HU196627B (en) | Microbiological process for producing y alpha-hydroxy-4-androstene-3,17-dione |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |