NO20052521L - Substituert 4-amino-1-(pyridylmetyl)piperidin og beslektede forbindelser - Google Patents

Substituert 4-amino-1-(pyridylmetyl)piperidin og beslektede forbindelser

Info

Publication number
NO20052521L
NO20052521L NO20052521A NO20052521A NO20052521L NO 20052521 L NO20052521 L NO 20052521L NO 20052521 A NO20052521 A NO 20052521A NO 20052521 A NO20052521 A NO 20052521A NO 20052521 L NO20052521 L NO 20052521L
Authority
NO
Norway
Prior art keywords
compounds
pyridylmethyl
piperidine
amino
related compounds
Prior art date
Application number
NO20052521A
Other languages
English (en)
Inventor
Mathai Mammen
Richard Wilson
Yan Chen
Sarah Dunham
Adam Hughes
Craig Husfeld
Yu-Hua Ji
Li Li
Trevor Mischki
Ioanna Stergiades
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Publication of NO20052521L publication Critical patent/NO20052521L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Det er beskrevet 4-amino-l-(pyridylmetyl)piperidin og beslektede forbindelser og farmasøytisk akseptable salter derav som er nyttige som muskariniske reseptorantagonister. Det er også beskrevet farmasøytiske preparater inneholdende slike forbindelser; fremgangsmåter og mellomprodukter som er nyttige for fremstilling av slike forbindelser og fremgangsmåter for behandling av sykdomstilstander som er formidlet ved muskariniske reseptorer, så som overaktiv blære, irritabel tarmsyndrom og kronisk, obstruktiv, pulmonar sykdom, ved anvendelse av slike forbindelser.
NO20052521A 2002-10-30 2005-05-25 Substituert 4-amino-1-(pyridylmetyl)piperidin og beslektede forbindelser NO20052521L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42222902P 2002-10-30 2002-10-30
US48648303P 2003-07-11 2003-07-11
PCT/US2003/034444 WO2004041806A2 (en) 2002-10-30 2003-10-29 Substituted 4-amino-1-(pyridylmethyl) piperidine as muscarinic receptor antagonists

Publications (1)

Publication Number Publication Date
NO20052521L true NO20052521L (no) 2005-05-25

Family

ID=32314442

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052521A NO20052521L (no) 2002-10-30 2005-05-25 Substituert 4-amino-1-(pyridylmetyl)piperidin og beslektede forbindelser

Country Status (20)

Country Link
US (2) US7285564B2 (no)
EP (1) EP1556372B1 (no)
JP (2) JP4448492B2 (no)
KR (1) KR20050061504A (no)
AR (1) AR041855A1 (no)
AT (1) ATE363482T1 (no)
AU (1) AU2003285100A1 (no)
BR (1) BR0315778A (no)
CA (1) CA2500800A1 (no)
DE (1) DE60314170T2 (no)
EC (1) ECSP055762A (no)
ES (1) ES2287543T3 (no)
IS (1) IS7780A (no)
MX (1) MXPA05004507A (no)
NO (1) NO20052521L (no)
PE (1) PE20040606A1 (no)
PL (1) PL376716A1 (no)
RU (1) RU2005116239A (no)
TW (2) TWI295669B (no)
WO (1) WO2004041806A2 (no)

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TW200510298A (en) 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds
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WO2005087763A1 (en) * 2004-03-11 2005-09-22 Theravance, Inc. Diphenylmethyl compounds useful as muscarinic receptor antagonists
TW200540154A (en) * 2004-06-10 2005-12-16 Theravance Inc Crystalline form of a substituted pyrrolidine compound
TW200628465A (en) 2004-10-28 2006-08-16 Theravance Inc Process for preparing substituted 4-amino-1-(pyridylmethyl) piperidine and related compounds
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US7786308B2 (en) * 2005-03-28 2010-08-31 Vertex Pharmaceuticals Incorporated Muscarinic modulators
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WO2009153649A1 (en) * 2008-06-19 2009-12-23 Medichem, S.A. Process for preparing 3-substituted pyrrolidine compounds
CN102638987A (zh) * 2009-10-07 2012-08-15 默沙东公司 使用β3肾上腺素能受体激动剂和抗毒蕈碱药剂的组合疗法
US20110281853A1 (en) 2010-05-12 2011-11-17 Rishi Arora Compositions and methods for treating or preventing atrial fibrillation
KR20130135239A (ko) * 2010-08-03 2013-12-10 앨씨알엑스, 인크. 과민성 방광 치료를 위한 베타-3 아드레날린 수용체 작용제 및 무스카린 수용체 길항제의 약학적 배합제
US9522129B2 (en) 2010-08-03 2016-12-20 Velicept Therapeutics, Inc. Pharmaceutical Combination
US9907767B2 (en) 2010-08-03 2018-03-06 Velicept Therapeutics, Inc. Pharmaceutical compositions and the treatment of overactive bladder
TW201338772A (zh) * 2012-02-09 2013-10-01 Altherx Inc 藥學組合物
US9956194B2 (en) 2014-12-03 2018-05-01 Velicept Therapeutics, Inc. Compositions and methods of using modified release solabegron for lower urinary tract symptoms
PT3365321T (pt) 2015-10-23 2024-01-12 B3Ar Therapeutics Inc Zwiterião de solabegron e suas utilizações

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Also Published As

Publication number Publication date
US7285564B2 (en) 2007-10-23
BR0315778A (pt) 2005-09-06
US20040122014A1 (en) 2004-06-24
TWI295669B (en) 2008-04-11
JP2010059214A (ja) 2010-03-18
US20080091034A1 (en) 2008-04-17
ES2287543T3 (es) 2007-12-16
RU2005116239A (ru) 2006-01-27
ECSP055762A (es) 2005-07-06
CA2500800A1 (en) 2004-05-21
DE60314170D1 (de) 2007-07-12
TW200800953A (en) 2008-01-01
WO2004041806A2 (en) 2004-05-21
DE60314170T2 (de) 2008-01-24
AR041855A1 (es) 2005-06-01
PL376716A1 (pl) 2006-01-09
JP2006512408A (ja) 2006-04-13
JP4448492B2 (ja) 2010-04-07
MXPA05004507A (es) 2005-10-18
EP1556372B1 (en) 2007-05-30
AU2003285100A1 (en) 2004-06-07
PE20040606A1 (es) 2004-09-08
IS7780A (is) 2005-03-31
KR20050061504A (ko) 2005-06-22
TW200418833A (en) 2004-10-01
EP1556372A2 (en) 2005-07-27
ATE363482T1 (de) 2007-06-15
WO2004041806A3 (en) 2004-08-05
US8030502B2 (en) 2011-10-04

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