NO20043610L - Fenylpyrimidinaminer som IgE inhibitorer - Google Patents

Fenylpyrimidinaminer som IgE inhibitorer

Info

Publication number
NO20043610L
NO20043610L NO20043610A NO20043610A NO20043610L NO 20043610 L NO20043610 L NO 20043610L NO 20043610 A NO20043610 A NO 20043610A NO 20043610 A NO20043610 A NO 20043610A NO 20043610 L NO20043610 L NO 20043610L
Authority
NO
Norway
Prior art keywords
phenylpyrimidinamines
ige inhibitors
ige
inhibitors
Prior art date
Application number
NO20043610A
Other languages
English (en)
Norwegian (no)
Inventor
Peter Ettmayer
Murty Bulusu
Klaus Weigand
Max Woisetschlager
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0202381A external-priority patent/GB0202381D0/en
Priority claimed from GB0221953A external-priority patent/GB0221953D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20043610L publication Critical patent/NO20043610L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20043610A 2002-02-01 2004-08-30 Fenylpyrimidinaminer som IgE inhibitorer NO20043610L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0202381A GB0202381D0 (en) 2002-02-01 2002-02-01 Organic compounds
GB0221953A GB0221953D0 (en) 2002-09-20 2002-09-20 Organic compounds
PCT/EP2003/000973 WO2003063871A1 (en) 2002-02-01 2003-01-31 Phenylpyrimidine amines as ige inhibitors

Publications (1)

Publication Number Publication Date
NO20043610L true NO20043610L (no) 2004-10-05

Family

ID=27665364

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043610A NO20043610L (no) 2002-02-01 2004-08-30 Fenylpyrimidinaminer som IgE inhibitorer

Country Status (23)

Country Link
US (2) US20050119255A1 (pt)
EP (1) EP1474146B1 (pt)
JP (1) JP4393198B2 (pt)
KR (1) KR20040081159A (pt)
CN (2) CN101684097A (pt)
AR (1) AR038368A1 (pt)
AT (1) ATE406165T1 (pt)
AU (1) AU2003206810B2 (pt)
BR (1) BR0307379A (pt)
CA (1) CA2471883C (pt)
DE (1) DE60323205D1 (pt)
EC (1) ECSP045213A (pt)
ES (1) ES2312749T3 (pt)
IL (1) IL162766A0 (pt)
MX (1) MXPA04007395A (pt)
NO (1) NO20043610L (pt)
NZ (1) NZ534229A (pt)
PE (1) PE20030983A1 (pt)
PL (1) PL370666A1 (pt)
PT (1) PT1474146E (pt)
RU (1) RU2004126614A (pt)
TW (1) TW200302728A (pt)
WO (1) WO2003063871A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050014753A1 (en) * 2003-04-04 2005-01-20 Irm Llc Novel compounds and compositions as protein kinase inhibitors
AU2004261484A1 (en) * 2003-07-30 2005-02-10 Cyclacel Limited 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors
JPWO2005040135A1 (ja) * 2003-10-24 2007-03-08 小野薬品工業株式会社 抗ストレス薬およびその医薬用途
EP1933839A1 (en) * 2005-09-29 2008-06-25 Novartis AG Phenyl-(4-phenyl-pyrimidin-2-yl)-amines for enhancing immunotolerance
JP5670731B2 (ja) 2007-08-15 2015-02-18 サイトキネティクス・インコーポレーテッドCytokinetics Incorporated ある種の化学物質、組成物、および方法
AU2020407604A1 (en) 2019-12-20 2022-07-21 Ikena Oncology, Inc. 4-phenyl-n-(phenyl)thiazol-2-amine derivatives and related compounds as aryl hydrocarbon receptor (AHR) agonists for the treatment of e.g. angiogenesis implicated or inflammatory disorders

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1185039A (en) 1966-03-31 1970-03-18 Ici Ltd Pyrimidine Derivatives and Compositions containing them
GB2001069B (en) 1977-07-12 1982-01-20 Scras Pyrimidine derivatives
AU5319479A (en) 1978-12-22 1980-06-26 Ici Australia Limited Pyrimidinyl amino phenoxy carboxylate derivatives
US4351939A (en) * 1980-10-16 1982-09-28 Mead Johnson & Company Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process
DE3270906D1 (en) * 1982-01-14 1986-06-05 Merck Patent Gmbh Liquid crystal mixtures
FR2536071B1 (fr) 1982-11-12 1986-07-11 Sanofi Sa Sels acides de 2-piperazinopyrimidine, procede pour leur preparation et compositions pharmaceutiques en contenant
FR2547821B1 (fr) * 1983-06-24 1985-12-06 Sanofi Sa Sel de 2-piperazinopyrimidine, procede pour sa preparation et compositions pharmaceutiques en contenant
US4659363A (en) 1983-07-25 1987-04-21 Ciba-Geigy Corporation N-(2-nitrophenyl)-2-aminopyrimidine derivatives, the preparation and use thereof
EP0164204A1 (en) 1984-05-12 1985-12-11 FISONS plc Novel pharmaceutically useful pyrimidines
EP0172786B1 (de) * 1984-06-25 1991-01-30 Ciba-Geigy Ag Pyrimidinderivate wirksam als Schädlingsbekämpfungsmittel
ES2087056T3 (es) 1986-01-13 1996-07-16 American Cyanamid Co 2-pirimidinaminas sustituidas en las posiciones 4, 5 y 6.
DE3614060A1 (de) 1986-04-23 1987-10-29 Schering Ag Pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
EP0254259A3 (en) 1986-07-21 1989-11-23 Otsuka Pharmaceutical Factory, Inc. P-aminophenol derivatives
DE3788494D1 (de) * 1986-10-13 1994-01-27 Ciba Geigy Harnstoffe.
US4826990A (en) 1987-09-30 1989-05-02 American Home Products Corporation 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
US4973690A (en) * 1988-04-12 1990-11-27 Ciba-Geigy Corporation Novel ureas
ES2058589T3 (es) * 1988-04-12 1994-11-01 Ciba Geigy Ag Ureas.
US4966622A (en) * 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
JPH02308248A (ja) * 1989-05-24 1990-12-21 Fuji Photo Film Co Ltd アミノピリミジン系色素形成カプラーおよび該カプラーを含有するハロゲン化銀カラー写真感光材料
US5521184A (en) * 1992-04-03 1996-05-28 Ciba-Geigy Corporation Pyrimidine derivatives and processes for the preparation thereof
US5516775A (en) * 1992-08-31 1996-05-14 Ciba-Geigy Corporation Further use of pyrimidine derivatives
WO1995009853A1 (en) 1993-10-01 1995-04-13 Ciba-Geigy Ag Pharmacologically active pyridine derivatives and processes for the preparation thereof
ATE325113T1 (de) 1993-10-01 2006-06-15 Novartis Pharma Gmbh Pharmacologisch wirksame pyrimidinderivate und verfahren zu deren herstellung
US5612340A (en) 1993-10-01 1997-03-18 Ciba-Geigy Corporation Pyrimidineamine derivatives and processes for the preparation thereof
NZ274978A (en) * 1993-10-12 1998-04-27 Du Pont Merck Pharma 1n-alkyl-n-aryl pyrimidinamine derivatives and pharmaceutical compositions thereof
DE69530989T2 (de) 1994-08-13 2004-05-19 Yuhan Corp. Neue pyrimidinderivate und verfahren zu ihrer herstellung
GB9523675D0 (en) 1995-11-20 1996-01-24 Celltech Therapeutics Ltd Chemical compounds
WO1998024782A2 (en) 1996-12-05 1998-06-11 Amgen Inc. Substituted pyrimidine compounds and their use
US6187781B1 (en) * 1997-03-26 2001-02-13 Taisho Pharmaceutical Co., Ltd. 4-Tetrahydropyridylpyrimidine derivatives
IN188411B (pt) 1997-03-27 2002-09-21 Yuhan Corp
US6440965B1 (en) 1997-10-15 2002-08-27 Krenitsky Pharmaceuticals, Inc. Substituted pyrimidine derivatives, their preparation and their use in the treatment of neurodegenerative or neurological disorders of the central nervous system
AU2516199A (en) * 1998-01-12 1999-07-26 Novartis Ag Pyridinylpyrimidine amines as immunoglobuline e (ige) synthesis inhibitors
WO1999038829A1 (fr) * 1998-01-28 1999-08-05 Shionogi & Co., Ltd. Nouveau compose tricyclique
ES2193660T3 (es) 1998-03-27 2003-11-01 Janssen Pharmaceutica Nv Derivados de pirimidina inhibidores de vih.
AR023052A1 (es) 1998-09-25 2002-09-04 Mitsuharu Yoshimura Milton Derivados de pirimidona
SK286264B6 (sk) * 1998-11-17 2008-06-06 Kumiai Chemical Industry Co., Ltd. Derivát pyrimidinylbenzimidazolu alebo triazinylbenzimidazolu, medziprodukty na jeho prípravu a poľnohospodársky/záhradnícky fungicíd s jeho obsahom
GB9828511D0 (en) 1998-12-24 1999-02-17 Zeneca Ltd Chemical compounds
EP1180520B1 (en) 1999-04-28 2007-06-20 Institute of Medicinal Molecular Design, Inc. Pyrimidine carboxylic acid derivatives
GB9914258D0 (en) 1999-06-18 1999-08-18 Celltech Therapeutics Ltd Chemical compounds
GB0003224D0 (en) 2000-02-11 2000-04-05 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
US7759357B2 (en) 2010-07-20
KR20040081159A (ko) 2004-09-20
US20070281956A1 (en) 2007-12-06
NZ534229A (en) 2005-04-29
US20050119255A1 (en) 2005-06-02
RU2004126614A (ru) 2005-05-27
IL162766A0 (en) 2005-11-20
PE20030983A1 (es) 2004-01-26
BR0307379A (pt) 2004-12-28
CA2471883C (en) 2010-12-07
EP1474146B1 (en) 2008-08-27
CN1622807A (zh) 2005-06-01
AR038368A1 (es) 2005-01-12
CN101684097A (zh) 2010-03-31
DE60323205D1 (en) 2008-10-09
ES2312749T3 (es) 2009-03-01
JP2005516051A (ja) 2005-06-02
PT1474146E (pt) 2008-12-05
EP1474146A1 (en) 2004-11-10
ATE406165T1 (de) 2008-09-15
JP4393198B2 (ja) 2010-01-06
TW200302728A (en) 2003-08-16
AU2003206810B2 (en) 2006-06-29
MXPA04007395A (es) 2005-06-17
PL370666A1 (en) 2005-05-30
WO2003063871A1 (en) 2003-08-07
CA2471883A1 (en) 2003-08-07
ECSP045213A (es) 2004-09-28

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application