NO20033540L - 6-substituerte pyrido-pyrimidiner - Google Patents

6-substituerte pyrido-pyrimidiner

Info

Publication number
NO20033540L
NO20033540L NO20033540A NO20033540A NO20033540L NO 20033540 L NO20033540 L NO 20033540L NO 20033540 A NO20033540 A NO 20033540A NO 20033540 A NO20033540 A NO 20033540A NO 20033540 L NO20033540 L NO 20033540L
Authority
NO
Norway
Prior art keywords
pyrimidines
substituted pyrido
pyrido
substituted
Prior art date
Application number
NO20033540A
Other languages
English (en)
Other versions
NO20033540D0 (no
NO326133B1 (no
Inventor
Jeffrey Jian Chen
James Patrick Dunn
David Michael Goldstein
Christophe Martin Stahl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20033540L publication Critical patent/NO20033540L/no
Publication of NO20033540D0 publication Critical patent/NO20033540D0/no
Publication of NO326133B1 publication Critical patent/NO326133B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20033540A 2001-02-12 2003-08-11 6-substituerte pyrido-pyrimidiner, fremgangsmate for fremstilling av slike, farmasoytiske preparater inneholdende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom NO326133B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26837501P 2001-02-12 2001-02-12
US33465401P 2001-11-30 2001-11-30
PCT/EP2002/001106 WO2002064594A2 (en) 2001-02-12 2002-02-04 6-substituted pyrido-pyrimidines

Publications (3)

Publication Number Publication Date
NO20033540L true NO20033540L (no) 2003-08-11
NO20033540D0 NO20033540D0 (no) 2003-08-11
NO326133B1 NO326133B1 (no) 2008-10-06

Family

ID=26953040

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20033540A NO326133B1 (no) 2001-02-12 2003-08-11 6-substituerte pyrido-pyrimidiner, fremgangsmate for fremstilling av slike, farmasoytiske preparater inneholdende slike samt anvendelse av slike for fremstilling av medikament for behandling av sykdom

Country Status (32)

Country Link
US (3) US6696566B2 (no)
EP (1) EP1361880B1 (no)
JP (1) JP4064818B2 (no)
KR (1) KR100639772B1 (no)
CN (1) CN100376571C (no)
AR (1) AR035854A1 (no)
AT (1) ATE305303T1 (no)
AU (1) AU2002256615B2 (no)
BR (1) BRPI0207172B8 (no)
CA (1) CA2434834C (no)
CZ (1) CZ20032416A3 (no)
DE (1) DE60206363T2 (no)
DK (1) DK1361880T3 (no)
ES (1) ES2249574T3 (no)
HK (1) HK1066170A1 (no)
HR (1) HRP20030624B1 (no)
HU (1) HU229604B1 (no)
IL (2) IL156872A0 (no)
JO (1) JO2410B1 (no)
MA (1) MA26993A1 (no)
MX (1) MXPA03007166A (no)
MY (1) MY131518A (no)
NO (1) NO326133B1 (no)
NZ (1) NZ526961A (no)
PA (1) PA8539201A1 (no)
PE (1) PE20020976A1 (no)
PL (1) PL366918A1 (no)
RU (1) RU2269527C2 (no)
SK (1) SK11322003A3 (no)
WO (1) WO2002064594A2 (no)
YU (1) YU63703A (no)
ZA (1) ZA200305938B (no)

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WO2002064594A2 (en) 2001-02-12 2002-08-22 F. Hoffmann-La Roche Ag 6-substituted pyrido-pyrimidines
GEP20063909B (en) * 2002-01-22 2006-08-25 Warner Lambert Co 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d] PYRIMIDIN-7-ONES
RU2310657C2 (ru) 2002-04-03 2007-11-20 Ф.Хоффманн-Ля Рош Аг Имидазоконденсированные соединения и фармацевтическая композиция, содержащая их
JP4252534B2 (ja) * 2002-08-06 2009-04-08 エフ．ホフマン−ラ ロシュ アーゲー ｐ−３８ＭＡＰキナーゼインヒビターとしての６−アルコキシ−ピリド−ピリミジン類
JP2006516548A (ja) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
MXPA05009063A (es) * 2003-02-26 2005-12-12 Sugen Inc Compuestos de aminoheteroarilo como inhibidores de proteina cinasa.
ES2279361T3 (es) * 2003-04-16 2007-08-16 F. Hoffmann-La Roche Ag Derivados de (6-(fenoxi)-pirido-3,4-dipirimidin-2-il)-amina como inhibidores de p38 kinasa para el tratamiento de estados inflamatorios tal como artritis reumatoide.
ES2281843T3 (es) * 2003-11-13 2007-10-01 F. Hoffmann-La Roche Ag Pirido-7-pirimidin-7-onas sustituidas con hidroxialquilo.
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US20060142312A1 (en) * 2004-12-23 2006-06-29 Pfizer Inc C6-aryl and heteroaryl substituted pyrido[2,3-D] pyrimidin-7-ones
US20090036472A1 (en) * 2005-02-02 2009-02-05 Palle Venkata P Azabicyclo derivatives as anti-inflammatory agents
CA2606760C (en) * 2005-05-04 2014-12-23 Renovis, Inc. Tetrahydronaphthyridine and tetrahydropyrido[4,3-d]pyrimidine compounds and compositions thereof useful in the treatment of conditions associated with neurological and inflammatory disorders and disfunctions
ATE449097T1 (de) * 2005-07-21 2009-12-15 Hoffmann La Roche Pyridoä2,3-düpyrimidin-2,4-diamin-verbindungen als ptpib-hemmer
RU2008108898A (ru) * 2005-08-09 2009-09-20 Айрм Ллк (Bm) Соединения и композиции в качестве ингибиторов протеинкиназы
WO2007022946A1 (de) 2005-08-21 2007-03-01 Abbott Gmbh & Co. Kg Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
JO2783B1 (en) * 2005-09-30 2014-03-15 نوفارتيس ايه جي Compounds 2-Amino-7, 8-dihydro-6H-Bayredo (3,4-D) Pyrimidine-5-Ones
WO2008150260A1 (en) * 2007-06-06 2008-12-11 Gpc Biotech, Inc. 8-oxy-2-aminopyrido (2, 3-d) pyrimidin-7-one derivatives as kinase inhibitors and anticancer agents
WO2008078249A1 (en) * 2006-12-21 2008-07-03 Ranbaxy Laboratories Limited Anti-inflammatory agents
CA2685597C (en) 2007-05-07 2012-10-02 Amgen Inc. Pyrazolo-pyridinone and pyrazolo-pyrazinone compounds as p38 modulators, process for their preparation, and their pharmaceutical use
EP2158182A2 (en) 2007-06-15 2010-03-03 F. Hoffmann-Roche AG A novel process for the preparation of 3-amino-pentan-1,5-diol
US8367671B2 (en) 2008-03-21 2013-02-05 Amgen Inc. Pyrazolo[3.4-B]pyrazine compounds as p38 modulators and methods of use as anti-inflamatory agents
EP2112150B1 (en) 2008-04-22 2013-10-16 Forma Therapeutics, Inc. Improved raf inhibitors
JP2012505927A (ja) * 2008-10-22 2012-03-08 エフ．ホフマン−ラ ロシュ アーゲー Ｊｎｋのピリミジニルピリドン阻害剤
WO2010071846A2 (en) 2008-12-19 2010-06-24 Afraxis, Inc. Compounds for treating neuropsychiatric conditions
CA2776770A1 (en) 2009-10-09 2011-04-14 Afraxis, Inc. 8-ethyl-6-(aryl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders
KR101754664B1 (ko) * 2009-12-18 2017-07-06 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 치환된 피리도〔2,3-ｄ〕피리미딘-7(8ｈ)-온스 및 이의 치료 용도
JP6631616B2 (ja) 2014-07-26 2020-01-15 ノース・アンド・サウス・ブラザー・ファーマシー・インベストメント・カンパニー・リミテッド ＣＤＫ阻害剤としての２−アミノ−ピリド［２，３−ｄ］ピリミジン−７（８Ｈ）−オン誘導体及びその使用
PE20190376A1 (es) * 2016-06-08 2019-03-08 Support Venture Gmbh Combinaciones farmaceuticas para el tratamiento del cancer
EP3497103B1 (en) 2016-08-15 2021-05-05 Pfizer Inc. Pyridopyrimdinone cdk2/4/6 inhibitors
EA201990220A1 (ru) 2016-08-17 2019-08-30 Суппорт-Венче Гмбх Способ предотвращения или лечения потери слуха
WO2018132550A1 (en) 2017-01-11 2018-07-19 The General Hospital Corporation Voltage gated sodium channel imaging agents
US11576916B2 (en) * 2017-04-04 2023-02-14 Kinarus Ag Methods of preventing or treating ophthalmic diseases
CN115322193A (zh) * 2017-08-31 2022-11-11 达纳-法伯癌症研究所股份有限公司 Egfr和/或her2抑制剂和使用方法
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US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
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TW202112368A (zh) 2019-06-13 2021-04-01 荷蘭商法西歐知識產權股份有限公司 用於治療有關dux4表現之疾病的抑制劑組合
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GEP20063909B (en) * 2002-01-22 2006-08-25 Warner Lambert Co 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d] PYRIMIDIN-7-ONES

Also Published As

Publication number Publication date
HRP20030624B1 (en) 2007-03-31
HK1066170A1 (en) 2005-03-18
DE60206363D1 (de) 2006-02-09
US20040116698A1 (en) 2004-06-17
WO2002064594A3 (en) 2003-01-09
US7169794B2 (en) 2007-01-30
HRP20030624A2 (en) 2005-06-30
JO2410B1 (en) 2007-06-17
KR20040018254A (ko) 2004-03-02
JP4064818B2 (ja) 2008-03-19
ATE305303T1 (de) 2005-10-15
IL156872A (en) 2009-07-20
MY131518A (en) 2007-08-30
NO20033540D0 (no) 2003-08-11
MXPA03007166A (es) 2003-11-18
CZ20032416A3 (cs) 2004-07-14
BRPI0207172B8 (pt) 2021-05-25
PA8539201A1 (es) 2004-08-31
HU229604B1 (en) 2014-02-28
US20030171584A1 (en) 2003-09-11
SK11322003A3 (en) 2004-10-05
JP2004525896A (ja) 2004-08-26
YU63703A (sh) 2006-05-25
CN100376571C (zh) 2008-03-26
MA26993A1 (fr) 2004-12-20
PE20020976A1 (es) 2002-10-29
AR035854A1 (es) 2004-07-21
KR100639772B1 (ko) 2006-10-30
CA2434834C (en) 2010-09-14
BRPI0207172B1 (pt) 2019-04-09
BR0207172A (pt) 2004-03-30
DK1361880T3 (da) 2006-01-23
US7449581B2 (en) 2008-11-11
RU2269527C2 (ru) 2006-02-10
EP1361880B1 (en) 2005-09-28
ZA200305938B (en) 2005-01-26
HUP0303458A3 (en) 2012-12-28
CN1503672A (zh) 2004-06-09
US20070135458A1 (en) 2007-06-14
WO2002064594A2 (en) 2002-08-22
AU2002256615B2 (en) 2007-09-13
IL156872A0 (en) 2004-02-08
PL366918A1 (en) 2005-02-07
HUP0303458A2 (hu) 2004-01-28
EP1361880A2 (en) 2003-11-19
US6696566B2 (en) 2004-02-24
CA2434834A1 (en) 2002-08-22
NO326133B1 (no) 2008-10-06
ES2249574T3 (es) 2006-04-01
DE60206363T2 (de) 2006-07-06
NZ526961A (en) 2005-03-24
RU2003125887A (ru) 2005-03-20

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