NO20021781L - Heteroalkylamino-substituerte bicykliske nitrogenheterocykler som inhibitorer for P38-proteinkinase - Google Patents

Heteroalkylamino-substituerte bicykliske nitrogenheterocykler som inhibitorer for P38-proteinkinase

Info

Publication number
NO20021781L
NO20021781L NO20021781A NO20021781A NO20021781L NO 20021781 L NO20021781 L NO 20021781L NO 20021781 A NO20021781 A NO 20021781A NO 20021781 A NO20021781 A NO 20021781A NO 20021781 L NO20021781 L NO 20021781L
Authority
NO
Norway
Prior art keywords
inhibitors
heteroalkylamino
protein kinase
substituted bicyclic
nitrogen heterocycles
Prior art date
Application number
NO20021781A
Other languages
English (en)
Norwegian (no)
Other versions
NO20021781D0 (no
Inventor
James Patrick Dunn
Lawrence Emerson Fisher
David Michael Goldstein
William Harris
Christopher Huw Hill
Ian Edward David Smith
Teresa Rosanne Welch
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20021781D0 publication Critical patent/NO20021781D0/no
Publication of NO20021781L publication Critical patent/NO20021781L/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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  • Ophthalmology & Optometry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Reproductive Health (AREA)
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  • Urology & Nephrology (AREA)
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NO20021781A 1999-10-21 2002-04-16 Heteroalkylamino-substituerte bicykliske nitrogenheterocykler som inhibitorer for P38-proteinkinase NO20021781L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16080399P 1999-10-21 1999-10-21
US21374300P 2000-06-22 2000-06-22
PCT/EP2000/010088 WO2001029042A1 (en) 1999-10-21 2000-10-13 Heteroalkylamino-substituted bicyclic nitrogen heterocycles as inhibitors of p38 protein kinase

Publications (2)

Publication Number Publication Date
NO20021781D0 NO20021781D0 (no) 2002-04-16
NO20021781L true NO20021781L (no) 2002-04-18

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ID=26857240

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021781A NO20021781L (no) 1999-10-21 2002-04-16 Heteroalkylamino-substituerte bicykliske nitrogenheterocykler som inhibitorer for P38-proteinkinase

Country Status (27)

Country Link
US (1) US6451804B1 (hr)
EP (1) EP1228070B1 (hr)
JP (1) JP3961830B2 (hr)
KR (1) KR100523120B1 (hr)
CN (1) CN1171889C (hr)
AR (1) AR026084A1 (hr)
AT (1) ATE353329T1 (hr)
AU (1) AU776250B2 (hr)
BR (1) BR0015243A (hr)
CA (1) CA2388142C (hr)
CZ (1) CZ20021744A3 (hr)
DE (1) DE60033307T2 (hr)
ES (1) ES2280247T3 (hr)
HK (1) HK1051039A1 (hr)
HR (1) HRP20020328A2 (hr)
HU (1) HUP0203564A3 (hr)
IL (1) IL149100A0 (hr)
MA (1) MA26837A1 (hr)
MX (1) MXPA02003950A (hr)
NO (1) NO20021781L (hr)
NZ (1) NZ518119A (hr)
PE (1) PE20010758A1 (hr)
PL (1) PL357502A1 (hr)
RU (1) RU2265606C2 (hr)
TR (1) TR200201057T2 (hr)
WO (1) WO2001029042A1 (hr)
YU (1) YU29102A (hr)

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AU2003245989A1 (en) 2002-07-09 2004-01-23 Boehringer Ingelheim Pharma Gmbh And Co. Kg Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases
PA8577501A1 (es) 2002-07-25 2004-02-07 Warner Lambert Co Inhibidores de quinasas
WO2004014907A1 (en) * 2002-08-06 2004-02-19 F. Hoffmann-La Roche Ag 6-alkoxy-pyrido-pyrimidines as p-38 map kinase inhibitors
US7084270B2 (en) * 2002-08-14 2006-08-01 Hoffman-La Roche Inc. Pyrimido compounds having antiproliferative activity
US7129351B2 (en) * 2002-11-04 2006-10-31 Hoffmann-La Roche Inc. Pyrimido compounds having antiproliferative activity
TW200413381A (en) * 2002-11-04 2004-08-01 Hoffmann La Roche Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents
CA2506565A1 (en) * 2002-11-18 2004-06-03 F. Hoffmann-La Roche Ag Diazinopyrimidines
MXPA05010765A (es) 2003-04-10 2005-12-12 Hoffmann La Roche Compuestos pirimido.
MXPA06001098A (es) 2003-07-29 2006-04-24 Irm Llc Compuestos y composiciones utiles como inhibidores de proteina cinasa.
US20060035893A1 (en) 2004-08-07 2006-02-16 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
AU2005279337A1 (en) 2004-08-31 2006-03-09 F. Hoffmann-La Roche Ag Amide derivatives of 7-amino-3-phenyl-dihydropyrimido [4,5-d]pyrimidinones, their manufacture and use as pharmaceutical agents
KR100853975B1 (ko) 2004-08-31 2008-08-25 에프. 호프만-라 로슈 아게 3-페닐 디히드로피리미도[4,5-d]피리미디논의 아미드유도체, 이의 제조 방법 및 약제로서의 용도
WO2006038112A1 (en) * 2004-10-01 2006-04-13 Warner-Lambert Company Llc Use of kinase inhibitors to promote neochondrogenesis
US20090131430A1 (en) * 2004-11-23 2009-05-21 Palle Venkata P Pyrido'2,3-dipyrimidines as anti-inflammatory agents
PE20060777A1 (es) 2004-12-24 2006-10-06 Boehringer Ingelheim Int Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
WO2006082492A1 (en) * 2005-02-02 2006-08-10 Ranbaxy Laboratories Limited Azabicyclo derivatives as anti-inflammatory agents
EP1966126A1 (de) * 2005-12-22 2008-09-10 Basf Se Verfahren zur herstellung von zyklischen o-alkylierten aminoalkoholen
ATE439361T1 (de) 2006-01-31 2009-08-15 Hoffmann La Roche 7h-pyridoä3,4-düpyrimidin-8-one, ihre herstellung und ihre verwendung als proteinkinaseinhibitoren
ES2301380B1 (es) 2006-08-09 2009-06-08 Laboratorios Almirall S.A. Nuevos derivados de 1,7-naftiridina.
ES2320955B1 (es) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
ES2329639B1 (es) 2007-04-26 2010-09-23 Laboratorios Almirall S.A. Nuevos derivados de 4,8-difenilpoliazanaftaleno.
EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
GB2452696B (en) * 2007-08-02 2009-09-23 Cambridge Entpr Ltd 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions
EP2108641A1 (en) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
ES2634470T3 (es) 2009-09-30 2017-09-27 Toray Industries, Inc. Derivado de 2,3-dihidro-1H-inden-2-ilurea y aplicación farmacéutica del mismo
EP2322176A1 (en) 2009-11-11 2011-05-18 Almirall, S.A. New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives
WO2011065800A2 (ko) * 2009-11-30 2011-06-03 주식회사 오스코텍 피리미딘 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물
US8754114B2 (en) 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
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