ATE353329T1 - Heteroalkylamino-substituierte bicyclische stickstoffheterocyclen - Google Patents
Heteroalkylamino-substituierte bicyclische stickstoffheterocyclenInfo
- Publication number
- ATE353329T1 ATE353329T1 AT00967864T AT00967864T ATE353329T1 AT E353329 T1 ATE353329 T1 AT E353329T1 AT 00967864 T AT00967864 T AT 00967864T AT 00967864 T AT00967864 T AT 00967864T AT E353329 T1 ATE353329 T1 AT E353329T1
- Authority
- AT
- Austria
- Prior art keywords
- heteroalkylamino
- substituted bicyclic
- nitrogen heterocycles
- bicyclic nitrogen
- heterocycles
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Obesity (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16080399P | 1999-10-21 | 1999-10-21 | |
US21374300P | 2000-06-22 | 2000-06-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE353329T1 true ATE353329T1 (de) | 2007-02-15 |
Family
ID=26857240
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00967864T ATE353329T1 (de) | 1999-10-21 | 2000-10-13 | Heteroalkylamino-substituierte bicyclische stickstoffheterocyclen |
Country Status (27)
Country | Link |
---|---|
US (1) | US6451804B1 (de) |
EP (1) | EP1228070B1 (de) |
JP (1) | JP3961830B2 (de) |
KR (1) | KR100523120B1 (de) |
CN (1) | CN1171889C (de) |
AR (1) | AR026084A1 (de) |
AT (1) | ATE353329T1 (de) |
AU (1) | AU776250B2 (de) |
BR (1) | BR0015243A (de) |
CA (1) | CA2388142C (de) |
CZ (1) | CZ20021744A3 (de) |
DE (1) | DE60033307T2 (de) |
ES (1) | ES2280247T3 (de) |
HK (1) | HK1051039A1 (de) |
HR (1) | HRP20020328A2 (de) |
HU (1) | HUP0203564A3 (de) |
IL (1) | IL149100A0 (de) |
MA (1) | MA26837A1 (de) |
MX (1) | MXPA02003950A (de) |
NO (1) | NO20021781L (de) |
NZ (1) | NZ518119A (de) |
PE (1) | PE20010758A1 (de) |
PL (1) | PL357502A1 (de) |
RU (1) | RU2265606C2 (de) |
TR (1) | TR200201057T2 (de) |
WO (1) | WO2001029042A1 (de) |
YU (1) | YU29102A (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL344248A1 (en) | 1998-05-26 | 2001-10-22 | Warner Lambert Co | Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation |
AU2003215675B2 (en) * | 2002-04-03 | 2007-07-12 | F. Hoffmann-La Roche Ag | Imidazo fused compounds |
EP1499320B1 (de) * | 2002-04-19 | 2007-08-22 | Smithkline Beecham Corporation | Neue verbindungen |
JP2005538066A (ja) | 2002-07-09 | 2005-12-15 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 新規な抗コリン作用薬及びp38キナーゼ阻害剤を用いた新規な医薬組成物 |
US7196090B2 (en) | 2002-07-25 | 2007-03-27 | Warner-Lambert Company | Kinase inhibitors |
RU2324695C2 (ru) * | 2002-08-06 | 2008-05-20 | Ф.Хоффманн-Ля Рош Аг | 6-АЛКОКСИПИРИДОПИРИМИДИНЫ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ АКТИВНОСТЬЮ ИНГИБИТОРОВ КИНАЗЫ МАР р38 |
US7084270B2 (en) * | 2002-08-14 | 2006-08-01 | Hoffman-La Roche Inc. | Pyrimido compounds having antiproliferative activity |
US7112676B2 (en) | 2002-11-04 | 2006-09-26 | Hoffmann-La Roche Inc. | Pyrimido compounds having antiproliferative activity |
TW200413381A (en) | 2002-11-04 | 2004-08-01 | Hoffmann La Roche | Novel amino-substituted dihydropyrimido [4,5-d]pyrimidinone derivatives, their manufacture and use as pharmaceutical agents |
AU2003283393A1 (en) * | 2002-11-18 | 2004-06-15 | F. Hoffmann-La Roche Ag | Diazinopyrimidines |
EP1615928A1 (de) | 2003-04-10 | 2006-01-18 | F.Hoffmann-La Roche Ag | Pyrimido-verbindungen |
WO2005011597A2 (en) * | 2003-07-29 | 2005-02-10 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
US20060035893A1 (en) | 2004-08-07 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders |
BRPI0514750A (pt) | 2004-08-31 | 2008-06-24 | Hoffmann La Roche | derivados amida de 7-amino-3-fenil-diidropirimido[4, 5-d]pirimidinonas, sua fabricação e uso como inibidores de proteìna cinase |
BRPI0514738A (pt) | 2004-08-31 | 2008-06-24 | Hoffmann La Roche | derivados de amida de 3-fenil-diidropirimido[4,5-d]pirimidinonas, sua fabricação e aplicação como agentes farmacêuticos |
WO2006038112A1 (en) * | 2004-10-01 | 2006-04-13 | Warner-Lambert Company Llc | Use of kinase inhibitors to promote neochondrogenesis |
EP1831215A1 (de) * | 2004-11-23 | 2007-09-12 | Ranbaxy Laboratories Limited | Pyrido[2,3-d]pyrimidine als entzüngungshemmende mittel |
PE20060777A1 (es) | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas |
US20090036472A1 (en) * | 2005-02-02 | 2009-02-05 | Palle Venkata P | Azabicyclo derivatives as anti-inflammatory agents |
US8173844B2 (en) * | 2005-12-22 | 2012-05-08 | Basf Se | Method for producing O-alkylated cyclic aminoalcohols |
US8058283B2 (en) | 2006-01-31 | 2011-11-15 | Hoffmann-La Roche Inc. | 7H-pyrido[3,4-D]pyrimidin-8-ones, their manufacture and use as protein kinase inhibitors |
ES2301380B1 (es) | 2006-08-09 | 2009-06-08 | Laboratorios Almirall S.A. | Nuevos derivados de 1,7-naftiridina. |
ES2320955B1 (es) | 2007-03-02 | 2010-03-16 | Laboratorios Almirall S.A. | Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida. |
ES2329639B1 (es) | 2007-04-26 | 2010-09-23 | Laboratorios Almirall S.A. | Nuevos derivados de 4,8-difenilpoliazanaftaleno. |
EP1992344A1 (de) | 2007-05-18 | 2008-11-19 | Institut Curie | P38 Alpha als therapeutisches Target für Erkrankungen, die mit einer FGFR3- Mutation assoziiert sind |
GB2452696B (en) * | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
EP2108641A1 (de) * | 2008-04-11 | 2009-10-14 | Laboratorios Almirall, S.A. | Neue substituierte Spiro[Cycloalkyl-1,3'-indo]-2'(1'H)-on-Derivate und ihre Verwendung als p38 mitogen-activated Kinase Inhibitoren |
EP2113503A1 (de) | 2008-04-28 | 2009-11-04 | Laboratorios Almirall, S.A. | Neue substituierte Indolin-2-on- Derivate und ihre Verwendung als p39 mitogen-activated Kinase Inhibitoren |
CN102574781B (zh) | 2009-09-30 | 2014-02-19 | 东丽株式会社 | 2,3-二氢-1h-茚-2-基脲衍生物及其药物用途 |
EP2322176A1 (de) | 2009-11-11 | 2011-05-18 | Almirall, S.A. | Neue 7-Phenyl-[1,2,4]triazol[4,3-a]pyridin-3(2H)on-Derivate |
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