TR200201057T2 - P38 protein kinazı inhibitörleri olarak heteroalkilamino ikameli bisiklik nitrojen heterosaykılları. - Google Patents

P38 protein kinazı inhibitörleri olarak heteroalkilamino ikameli bisiklik nitrojen heterosaykılları.

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Publication number
TR200201057T2
TR200201057T2 TR2002/01057T TR200201057T TR200201057T2 TR 200201057 T2 TR200201057 T2 TR 200201057T2 TR 2002/01057 T TR2002/01057 T TR 2002/01057T TR 200201057 T TR200201057 T TR 200201057T TR 200201057 T2 TR200201057 T2 TR 200201057T2
Authority
TR
Turkey
Prior art keywords
inhibitors
heteroalkylamino
protein kinase
nitrogen heterocycles
bicyclic nitrogen
Prior art date
Application number
TR2002/01057T
Other languages
English (en)
Inventor
Patrick Dunn James
Emerson Fisher Lawrence
Micheal Goldstein David
Harris William
Huw Hill Christopher
Edward David Smith Ian
Rosanne Welch Terase
Original Assignee
F.Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag
Publication of TR200201057T2 publication Critical patent/TR200201057T2/tr

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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Abstract

Bulus, R1, R2, R3, R4 ve n'nin basvuruda tanimlandigi gibi oldugu formül (1) ile temsil edilen bilesikler; ve ayri ayri izomerler, izomerlerin rasemik olmayan karisimlarini, ve bunlarin farmasötik olarak kabul gören tuzlarini saglar. Bilesikler, p38 önleyicidirler ve arterit, Crohn hastaligi, tahris olabilir barsak sendromu, yetiskin solunum zorlugu sendromu, kronik engelleyici akciger hastaligi, osteoporoz veya Alzheimer hastaliginin tedavisinde kullanilabilir.
TR2002/01057T 1999-10-21 2000-10-13 P38 protein kinazı inhibitörleri olarak heteroalkilamino ikameli bisiklik nitrojen heterosaykılları. TR200201057T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16080399P 1999-10-21 1999-10-21
US21374300P 2000-06-22 2000-06-22

Publications (1)

Publication Number Publication Date
TR200201057T2 true TR200201057T2 (tr) 2002-09-23

Family

ID=26857240

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/01057T TR200201057T2 (tr) 1999-10-21 2000-10-13 P38 protein kinazı inhibitörleri olarak heteroalkilamino ikameli bisiklik nitrojen heterosaykılları.

Country Status (27)

Country Link
US (1) US6451804B1 (tr)
EP (1) EP1228070B1 (tr)
JP (1) JP3961830B2 (tr)
KR (1) KR100523120B1 (tr)
CN (1) CN1171889C (tr)
AR (1) AR026084A1 (tr)
AT (1) ATE353329T1 (tr)
AU (1) AU776250B2 (tr)
BR (1) BR0015243A (tr)
CA (1) CA2388142C (tr)
CZ (1) CZ20021744A3 (tr)
DE (1) DE60033307T2 (tr)
ES (1) ES2280247T3 (tr)
HK (1) HK1051039A1 (tr)
HR (1) HRP20020328A2 (tr)
HU (1) HUP0203564A3 (tr)
IL (1) IL149100A0 (tr)
MA (1) MA26837A1 (tr)
MX (1) MXPA02003950A (tr)
NO (1) NO20021781L (tr)
NZ (1) NZ518119A (tr)
PE (1) PE20010758A1 (tr)
PL (1) PL357502A1 (tr)
RU (1) RU2265606C2 (tr)
TR (1) TR200201057T2 (tr)
WO (1) WO2001029042A1 (tr)
YU (1) YU29102A (tr)

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