NO20013161L - Preparater av ileum-gallesyretransportinhibitorer og kolesterylesteroverföringsproteininhibitorer for kardiovaskul¶reindikasjoner - Google Patents
Preparater av ileum-gallesyretransportinhibitorer og kolesterylesteroverföringsproteininhibitorer for kardiovaskul¶reindikasjonerInfo
- Publication number
- NO20013161L NO20013161L NO20013161A NO20013161A NO20013161L NO 20013161 L NO20013161 L NO 20013161L NO 20013161 A NO20013161 A NO 20013161A NO 20013161 A NO20013161 A NO 20013161A NO 20013161 L NO20013161 L NO 20013161L
- Authority
- NO
- Norway
- Prior art keywords
- inhibitors
- bile acid
- transfer protein
- ileum
- preparations
- Prior art date
Links
- 230000002526 effect on cardiovascular system Effects 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 239000003613 bile acid Substances 0.000 title 1
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 102000012336 Cholesterol Ester Transfer Proteins Human genes 0.000 abstract 2
- 108010061846 Cholesterol Ester Transfer Proteins Proteins 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 229940077672 Ileal bile acid transport inhibitor Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11395598P | 1998-12-23 | 1998-12-23 | |
| US14304799P | 1999-07-07 | 1999-07-07 | |
| PCT/US1999/027947 WO2000038726A1 (fr) | 1998-12-23 | 1999-12-17 | Combinaisons d'inhibiteurs de transport de l'acide biliaire ileal et d'inhibiteurs de la proteine de transfert de l'ester de cholesteryle utilisees dans le cadre de maladies cardio-vasculaires |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20013161D0 NO20013161D0 (no) | 2001-06-22 |
| NO20013161L true NO20013161L (no) | 2001-08-17 |
Family
ID=26811682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20013161A NO20013161L (no) | 1998-12-23 | 2001-06-22 | Preparater av ileum-gallesyretransportinhibitorer og kolesterylesteroverföringsproteininhibitorer for kardiovaskul¶reindikasjoner |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6458851B1 (fr) |
| EP (2) | EP1140188B1 (fr) |
| JP (1) | JP2002533412A (fr) |
| KR (1) | KR20010108046A (fr) |
| CN (1) | CN1342089A (fr) |
| AT (1) | ATE241386T1 (fr) |
| AU (1) | AU776620B2 (fr) |
| BR (1) | BR9916486A (fr) |
| CA (1) | CA2356422C (fr) |
| CZ (1) | CZ20012340A3 (fr) |
| DE (1) | DE69908414T2 (fr) |
| DK (1) | DK1140188T3 (fr) |
| EA (1) | EA005815B1 (fr) |
| ES (1) | ES2200587T3 (fr) |
| HK (2) | HK1041443A1 (fr) |
| HU (1) | HUP0201972A3 (fr) |
| IL (1) | IL143946A0 (fr) |
| MX (1) | MXPA01006471A (fr) |
| NO (1) | NO20013161L (fr) |
| NZ (1) | NZ512536A (fr) |
| PL (1) | PL348508A1 (fr) |
| PT (1) | PT1140188E (fr) |
| WO (1) | WO2000038726A1 (fr) |
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| BR9916486A (pt) * | 1998-12-23 | 2002-02-05 | Searle Llc | Combinações de inibidores do transporte de ácidos biliares no ìleo e inibidores da proteìna de transferência do ester colesteril para indicações cardiovasculares |
| CA2373073A1 (fr) * | 1999-05-07 | 2000-11-16 | Takeda Chemical Industries, Ltd. | Composes cycliques et leurs utilisations |
| SE0000772D0 (sv) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | Chemical compounds |
| EG26979A (en) | 2000-12-21 | 2015-03-01 | Astrazeneca Ab | Chemical compounds |
| GB0121337D0 (en) | 2001-09-04 | 2001-10-24 | Astrazeneca Ab | Chemical compounds |
| GB0121621D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| GB0121622D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| CN1582151A (zh) | 2001-09-08 | 2005-02-16 | 阿斯特拉曾尼卡有限公司 | 用于治疗高脂血症、具有回肠胆汁酸转运(ibat)抑制活性的苯并硫氮杂䓬和苯并硫杂二氮杂䓬衍生物 |
| KR20050044352A (ko) * | 2001-11-09 | 2005-05-12 | 아테로제닉스, 인코포레이티드 | 심혈관 병리의 역전 및 예방 방법 |
| EP1461069A2 (fr) * | 2001-12-29 | 2004-09-29 | Novo Nordisk A/S | Utilisation combinee d'un compose glp-1 et d'un autre medicament pour traiter la dyslipidemie |
| GB0209467D0 (en) | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
| GB0213669D0 (en) | 2002-06-14 | 2002-07-24 | Astrazeneca Ab | Chemical compounds |
| GB0304194D0 (en) | 2003-02-25 | 2003-03-26 | Astrazeneca Ab | Chemical compounds |
| GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
| MXPA06003357A (es) | 2003-09-26 | 2006-06-08 | Japan Tobacco Inc | Metodo para inhibir la produccion de lipoproteina remanente. |
| CA2624601C (fr) | 2004-10-06 | 2018-07-03 | The Brigham And Women's Hospital, Inc. | Pertinence de niveaux obtenus de marqueurs d'inflammation generalisee a la suite d'un traitement |
| US20060257450A1 (en) * | 2005-03-21 | 2006-11-16 | Sreenivasu Mudumba | Drug delivery systems for treatment of diseases or conditions |
| BRPI0608152A2 (pt) * | 2005-02-09 | 2009-11-10 | Macusight Inc | formulações para tratamento ocular |
| US8663639B2 (en) * | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
| WO2007092620A2 (fr) | 2006-02-09 | 2007-08-16 | Macusight, Inc. | Formulations stables et leurs procedes de preparation et d'utilisation |
| CA2645488C (fr) | 2006-03-23 | 2014-09-02 | Macusight, Inc. | Formulations comprenant de la rapamycine et methodes d'utilisation de celle-ci destinees aux maladies ou aux pathologies liees a la permeabilite vasculaire |
| WO2010062861A2 (fr) * | 2008-11-26 | 2010-06-03 | Satiogen Pharmaceuticals, Inc. | Inhibiteurs de recyclage de l'acide biliaire pour le traitement de l'obésité et du diabète |
| EP2575821B1 (fr) | 2010-05-26 | 2015-08-12 | Satiogen Pharmaceuticals, Inc. | Inhibiteurs de recyclage d'acide biliaire et satiogènes pour traitement du diabète, de l'obésité et d'états inflammatoires gastro-intestinaux |
| CA2815698C (fr) | 2010-11-08 | 2019-04-30 | Albireo Ab | Combinaison pharmaceutique comprenant un inhibiteur ibat et un liant d'acide biliaire |
| SI2637668T1 (sl) | 2010-11-08 | 2016-11-30 | Albiero Ab | IBAT inhibitorji za zdravljenje jetrnih bolezni |
| JP2012171911A (ja) | 2011-02-22 | 2012-09-10 | Kao Corp | Ｐｐａｒ活性化剤 |
| CN107375932B (zh) | 2011-10-28 | 2021-12-21 | 夏尔人类遗传性治疗公司 | 用于治疗小儿胆汁淤积性肝病的胆汁酸再循环抑制剂 |
| EA029581B1 (ru) | 2011-10-28 | 2018-04-30 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Применение ингибиторов рециркуляции желчных кислот для лечения холестатического заболевания печени или прурита |
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| KR20220082931A (ko) | 2014-06-25 | 2022-06-17 | 이에이 파마 가부시키가이샤 | 고형 제제 및 그의 착색 방지 또는 착색 감소 방법 |
| EP3012252A1 (fr) | 2014-10-24 | 2016-04-27 | Ferring BV | Formes crystallines d'Elobixibat |
| US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US10441605B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| CN108601744B (zh) | 2016-02-09 | 2022-01-04 | 阿尔比里奥公司 | 口服考来烯胺制剂及其用途 |
| JP6954927B2 (ja) | 2016-02-09 | 2021-10-27 | アルビレオ・アクチボラグ | 経口コレスチラミン製剤及びその使用 |
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| WO2019245449A1 (fr) | 2018-06-20 | 2019-12-26 | Albireo Ab | Formulation pharmaceutique à base d'odévixibat |
| US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
| US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
| US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| WO2020161216A1 (fr) | 2019-02-06 | 2020-08-13 | Albireo Ab | Composés de benzothiazépine et leur utilisation en tant que modulateurs de l'acide biliaire |
| AU2020218908A1 (en) | 2019-02-06 | 2021-08-26 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
| US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
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| CA3158276A1 (fr) | 2019-12-04 | 2021-06-10 | Per-Goran Gillberg | Composes de benzothia(di)azepine et leur utilisation en tant que modulateurs d'acide biliaire |
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| TW202134221A (zh) | 2019-12-04 | 2021-09-16 | 瑞典商艾爾比瑞歐公司 | 苯并噻二氮呯化合物及其作為膽酸調節劑之用途 |
| JP2023537285A (ja) | 2020-08-03 | 2023-08-31 | アルビレオ・アクチボラグ | ベンゾチア（ジ）アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
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| EP4255565A1 (fr) | 2020-12-04 | 2023-10-11 | Albireo AB | Composés de benzothia(di)azepine et leur utilisation en tant que modulateurs de l'acide biliaire |
| WO2023237728A1 (fr) | 2022-06-09 | 2023-12-14 | Albireo Ab | Traitement de l'hépatite |
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-
1999
- 1999-12-17 BR BR9916486-8A patent/BR9916486A/pt not_active Application Discontinuation
- 1999-12-17 WO PCT/US1999/027947 patent/WO2000038726A1/fr not_active Application Discontinuation
- 1999-12-17 HU HU0201972A patent/HUP0201972A3/hu unknown
- 1999-12-17 EP EP99965902A patent/EP1140188B1/fr not_active Expired - Lifetime
- 1999-12-17 KR KR1020017008085A patent/KR20010108046A/ko not_active Application Discontinuation
- 1999-12-17 NZ NZ512536A patent/NZ512536A/en unknown
- 1999-12-17 US US09/466,415 patent/US6458851B1/en not_active Expired - Fee Related
- 1999-12-17 PT PT99965902T patent/PT1140188E/pt unknown
- 1999-12-17 CZ CZ20012340A patent/CZ20012340A3/cs unknown
- 1999-12-17 IL IL14394699A patent/IL143946A0/xx unknown
- 1999-12-17 DK DK99965902T patent/DK1140188T3/da active
- 1999-12-17 CN CN99816268A patent/CN1342089A/zh active Pending
- 1999-12-17 MX MXPA01006471A patent/MXPA01006471A/es unknown
- 1999-12-17 EA EA200100705A patent/EA005815B1/ru not_active IP Right Cessation
- 1999-12-17 EP EP03011146A patent/EP1342475A1/fr not_active Withdrawn
- 1999-12-17 AT AT99965902T patent/ATE241386T1/de not_active IP Right Cessation
- 1999-12-17 PL PL99348508A patent/PL348508A1/xx not_active Application Discontinuation
- 1999-12-17 AU AU21578/00A patent/AU776620B2/en not_active Ceased
- 1999-12-17 JP JP2000590677A patent/JP2002533412A/ja active Pending
- 1999-12-17 DE DE69908414T patent/DE69908414T2/de not_active Expired - Fee Related
- 1999-12-17 CA CA002356422A patent/CA2356422C/fr not_active Expired - Fee Related
- 1999-12-17 ES ES99965902T patent/ES2200587T3/es not_active Expired - Lifetime
-
2001
- 2001-06-22 NO NO20013161A patent/NO20013161L/no not_active Application Discontinuation
-
2002
- 2002-04-10 HK HK02102732A patent/HK1041443A1/xx not_active IP Right Cessation
- 2002-07-23 US US10/200,599 patent/US20030203892A1/en not_active Abandoned
- 2002-08-22 HK HK02106168.1A patent/HK1044479A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000038726A1 (fr) | 2000-07-06 |
| HK1041443A1 (en) | 2002-07-12 |
| JP2002533412A (ja) | 2002-10-08 |
| US20030203892A1 (en) | 2003-10-30 |
| IL143946A0 (en) | 2002-04-21 |
| ATE241386T1 (de) | 2003-06-15 |
| PL348508A1 (en) | 2002-05-20 |
| DE69908414D1 (de) | 2003-07-03 |
| AU2157800A (en) | 2000-07-31 |
| DE69908414T2 (de) | 2004-04-01 |
| CA2356422C (fr) | 2008-09-16 |
| BR9916486A (pt) | 2002-02-05 |
| US6458851B1 (en) | 2002-10-01 |
| EP1140188B1 (fr) | 2003-05-28 |
| EA005815B1 (ru) | 2005-06-30 |
| PT1140188E (pt) | 2003-10-31 |
| NZ512536A (en) | 2003-11-28 |
| CZ20012340A3 (cs) | 2001-11-14 |
| HK1044479A1 (zh) | 2002-10-25 |
| EA200100705A1 (ru) | 2002-02-28 |
| MXPA01006471A (es) | 2004-03-10 |
| KR20010108046A (ko) | 2001-12-07 |
| EP1140188A1 (fr) | 2001-10-10 |
| AU776620B2 (en) | 2004-09-16 |
| NO20013161D0 (no) | 2001-06-22 |
| CA2356422A1 (fr) | 2000-07-06 |
| CN1342089A (zh) | 2002-03-27 |
| EP1342475A1 (fr) | 2003-09-10 |
| DK1140188T3 (da) | 2003-09-29 |
| HUP0201972A2 (en) | 2002-10-28 |
| HUP0201972A3 (en) | 2005-06-28 |
| ES2200587T3 (es) | 2004-03-01 |
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