NO20005452D0 - Matrise tildannet fra polymer- og hydrofobe forbindelser for bruk i medikamentavlevering - Google Patents
Matrise tildannet fra polymer- og hydrofobe forbindelser for bruk i medikamentavleveringInfo
- Publication number
- NO20005452D0 NO20005452D0 NO20005452A NO20005452A NO20005452D0 NO 20005452 D0 NO20005452 D0 NO 20005452D0 NO 20005452 A NO20005452 A NO 20005452A NO 20005452 A NO20005452 A NO 20005452A NO 20005452 D0 NO20005452 D0 NO 20005452D0
- Authority
- NO
- Norway
- Prior art keywords
- drug
- hydrophobic
- matrix
- integrated
- drug delivery
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8363698P | 1998-04-30 | 1998-04-30 | |
US09/255,179 US6423345B2 (en) | 1998-04-30 | 1999-02-22 | Matrices formed of polymer and hydrophobic compounds for use in drug delivery |
PCT/US1999/005187 WO1999056731A1 (en) | 1998-04-30 | 1999-03-08 | Matrices formed of polymer and hydrophobic compounds for use in drug delivery |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20005452D0 true NO20005452D0 (no) | 2000-10-27 |
NO20005452L NO20005452L (no) | 2000-12-29 |
NO324895B1 NO324895B1 (no) | 2007-12-27 |
Family
ID=26769533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20005452A NO324895B1 (no) | 1998-04-30 | 2000-10-27 | Poros polymermatriks tildannet fra polymer- og hydrofobforbindelser for bruk i medikamentavlevering, fremgangsmate for fremstilling av disse. |
Country Status (19)
Country | Link |
---|---|
US (5) | US6423345B2 (no) |
EP (1) | EP1073422B1 (no) |
JP (1) | JP5153032B2 (no) |
KR (1) | KR100703051B1 (no) |
CN (1) | CN1201729C (no) |
AT (1) | ATE319433T1 (no) |
AU (1) | AU746696B2 (no) |
BR (1) | BR9910340A (no) |
CA (1) | CA2329875C (no) |
DE (1) | DE69930240T2 (no) |
DK (1) | DK1073422T3 (no) |
ES (1) | ES2259472T3 (no) |
IL (2) | IL139252A0 (no) |
MX (1) | MXPA00010566A (no) |
NO (1) | NO324895B1 (no) |
NZ (1) | NZ508470A (no) |
PL (1) | PL196159B1 (no) |
PT (1) | PT1073422E (no) |
WO (1) | WO1999056731A1 (no) |
Families Citing this family (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6743777B1 (en) * | 1992-03-19 | 2004-06-01 | Eli Lilly And Company | Cyclic peptide antifungal agents and process for preparation thereof |
US6241762B1 (en) | 1998-03-30 | 2001-06-05 | Conor Medsystems, Inc. | Expandable medical device with ductile hinges |
US7208010B2 (en) | 2000-10-16 | 2007-04-24 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
US7208011B2 (en) * | 2001-08-20 | 2007-04-24 | Conor Medsystems, Inc. | Implantable medical device with drug filled holes |
US6423345B2 (en) * | 1998-04-30 | 2002-07-23 | Acusphere, Inc. | Matrices formed of polymer and hydrophobic compounds for use in drug delivery |
US7022683B1 (en) | 1998-05-13 | 2006-04-04 | Carrington Laboratories, Inc. | Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation |
AU752225B2 (en) * | 1998-07-17 | 2002-09-12 | Pacira Pharmaceuticals, Inc. | Biodegradable compositions for the controlled release of encapsulated substances |
CA2362481C (en) * | 1999-03-03 | 2008-11-04 | Eli Lilly And Company | Echinocandin pharmaceutical formulations containing micelle-forming surfactants |
KR20020003864A (ko) | 1999-03-03 | 2002-01-15 | 피터 지. 스트링거 | 에키노칸딘/탄수화물 착물 |
US7919119B2 (en) | 1999-05-27 | 2011-04-05 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
US6395300B1 (en) | 1999-05-27 | 2002-05-28 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
CN100376291C (zh) * | 1999-05-27 | 2008-03-26 | 阿库斯菲尔公司 | 多孔药物基质及其制造方法 |
CA2371836C (en) * | 1999-05-27 | 2006-01-31 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
US6610317B2 (en) | 1999-05-27 | 2003-08-26 | Acusphere, Inc. | Porous paclitaxel matrices and methods of manufacture thereof |
EP1642572A1 (en) * | 1999-05-27 | 2006-04-05 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
CA2395132A1 (en) * | 2000-01-05 | 2001-07-12 | Imarx Therapeutics, Inc. | Pharmaceutical formulations for the delivery of drugs having low aqueous solubility |
US20040009229A1 (en) * | 2000-01-05 | 2004-01-15 | Unger Evan Charles | Stabilized nanoparticle formulations of camptotheca derivatives |
US6589557B2 (en) * | 2000-06-15 | 2003-07-08 | Acusphere, Inc. | Porous celecoxib matrices and methods of manufacture thereof |
DE60112318T4 (de) * | 2000-10-16 | 2008-11-27 | Conor Medsystems, Inc., Menlo Park | Ausdehnbare medizinische Vorrichtung zur Abgabe eines nützlichen Agens |
US20020150621A1 (en) * | 2000-10-16 | 2002-10-17 | Kohane Daniel S. | Lipid-protein-sugar particles for drug delivery |
US7494669B2 (en) * | 2001-02-28 | 2009-02-24 | Carrington Laboratories, Inc. | Delivery of physiological agents with in-situ gels comprising anionic polysaccharides |
US6777000B2 (en) * | 2001-02-28 | 2004-08-17 | Carrington Laboratories, Inc. | In-situ gel formation of pectin |
BR0210518A (pt) * | 2001-06-22 | 2004-06-22 | Pfizer Prod Inc | Composições farmacêuticas de dispersões de drogas e polìmeros neutros |
US7056338B2 (en) * | 2003-03-28 | 2006-06-06 | Conor Medsystems, Inc. | Therapeutic agent delivery device with controlled therapeutic agent release rates |
US7842083B2 (en) | 2001-08-20 | 2010-11-30 | Innovational Holdings, Llc. | Expandable medical device with improved spatial distribution |
WO2003035051A2 (en) * | 2001-10-19 | 2003-05-01 | Inhale Therapeutic Systems, Inc. | The use of proton sequestering agents in drug formulations |
US9308220B2 (en) | 2001-12-11 | 2016-04-12 | Cosmo Technologies Limited | Pharmaceutical compositions for the oral administration of heparin or derivatives thereof |
ITMI20012599A1 (it) * | 2001-12-11 | 2003-06-11 | Cosmo Spa | Composizioni farmaceutiche per la somministrazione orale di eparina osuoi derivati, utili per la terapia di malattie infiammatorie dell'int |
JP4679822B2 (ja) | 2002-03-13 | 2011-05-11 | ノバルティス アーゲー | 医薬微粒子 |
US7008644B2 (en) * | 2002-03-20 | 2006-03-07 | Advanced Inhalation Research, Inc. | Method and apparatus for producing dry particles |
AU2003218308B2 (en) * | 2002-03-20 | 2006-07-20 | Advanced Inhalation Research, Inc. | hGH (human growth hormone) formulations for pulmonary administration |
US6991800B2 (en) * | 2002-06-13 | 2006-01-31 | Vicuron Pharmaceuticals Inc. | Antifungal parenteral products |
GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
EP1556018A1 (en) * | 2002-09-30 | 2005-07-27 | Acusphere, Inc. | Sustained release porous microparticles for inhalation |
JP2006505364A (ja) * | 2002-11-08 | 2006-02-16 | コナー メドシステムズ, インコーポレイテッド | 血管新生因子の局所供給を用いる、慢性全梗塞を処置するための拡張可能な医療装置および方法 |
GB0228571D0 (en) * | 2002-12-06 | 2003-01-15 | Novartis Ag | Organic compounds |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
US6962006B2 (en) * | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
US20040202692A1 (en) * | 2003-03-28 | 2004-10-14 | Conor Medsystems, Inc. | Implantable medical device and method for in situ selective modulation of agent delivery |
EP1610823B1 (en) | 2003-03-28 | 2011-09-28 | Innovational Holdings, LLC | Implantable medical device with continuous agent concentration gradient |
US20050031667A1 (en) * | 2003-03-31 | 2005-02-10 | Patel Rajesh A. | Implantable polymeric device for sustained release of dopamine agonist |
US20040247624A1 (en) * | 2003-06-05 | 2004-12-09 | Unger Evan Charles | Methods of making pharmaceutical formulations for the delivery of drugs having low aqueous solubility |
US7645474B1 (en) * | 2003-07-31 | 2010-01-12 | Advanced Cardiovascular Systems, Inc. | Method and system of purifying polymers for use with implantable medical devices |
US7785512B1 (en) | 2003-07-31 | 2010-08-31 | Advanced Cardiovascular Systems, Inc. | Method and system of controlled temperature mixing and molding of polymers with active agents for implantable medical devices |
WO2005025545A2 (en) * | 2003-09-17 | 2005-03-24 | Aderis Pharmaceuticals, Inc. | Pharmaceutical formulation for controlled release of selodenoson |
CN1856296A (zh) * | 2003-09-30 | 2006-11-01 | 阿库斯菲尔公司 | 可注射的、口服、或局部用缓释药物制剂 |
WO2005035606A1 (en) * | 2003-10-10 | 2005-04-21 | Samyang Corporation | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery |
US20050084455A1 (en) * | 2003-10-16 | 2005-04-21 | Council Of Scientific & Industrial Research | Inhalable biodegradable microparticles for target-specific drug delivery in tuberculosis and a process thereof |
US8157788B2 (en) * | 2003-11-06 | 2012-04-17 | Paolo L. Manfredi | Multi-site drug delivery platform |
US20050100577A1 (en) * | 2003-11-10 | 2005-05-12 | Parker Theodore L. | Expandable medical device with beneficial agent matrix formed by a multi solvent system |
ES2600577T3 (es) * | 2003-12-04 | 2017-02-09 | Bend Research, Inc. | Procedimiento de pulverización-solidificación que usa un extrusor para preparar composiciones en multipartículas de fármacos cristalinos |
DE602004014805D1 (de) * | 2003-12-04 | 2008-08-14 | Pfizer Prod Inc | Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten |
US6984403B2 (en) * | 2003-12-04 | 2006-01-10 | Pfizer Inc. | Azithromycin dosage forms with reduced side effects |
BRPI0416534A (pt) * | 2003-12-04 | 2007-01-09 | Pfizer Prod Inc | composições multiparticuladas com estabilidade melhorada |
CA2547239A1 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Azithromycin multiparticulate dosage forms by liquid-based processes |
WO2005053639A2 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Controlled release multiparticulates formed with dissolution enhancers |
WO2005053652A1 (en) | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride |
KR20050104152A (ko) | 2004-04-28 | 2005-11-02 | 최승호 | 경구용 약물의 흡수를 증진하는 약제학적 조성물 |
US7446131B1 (en) | 2004-06-10 | 2008-11-04 | The United States Of America As Represented By The Secretary Of Agriculture | Porous polymeric matrices made of natural polymers and synthetic polymers and optionally at least one cation and methods of making |
WO2006012502A2 (en) * | 2004-07-23 | 2006-02-02 | Rigel Pharmaceuticals, Inc. | Formulation of insoluble small molecule therapeutics in lipid-based carriers |
GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
US7862835B2 (en) * | 2004-10-27 | 2011-01-04 | Boston Scientific Scimed, Inc. | Method of manufacturing a medical device having a porous coating thereon |
US8128952B2 (en) * | 2005-01-12 | 2012-03-06 | Clemson University Research Foundation | Ligand-mediated controlled drug delivery |
DE102005002703C5 (de) * | 2005-01-19 | 2013-07-04 | Heraeus Kulzer Gmbh | Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung |
JP5178506B2 (ja) * | 2005-03-14 | 2013-04-10 | バイオベンション ホールディングス リミテッド | ドラッグデリバリー組成物と関連する方法 |
JP2009518443A (ja) * | 2005-12-06 | 2009-05-07 | リゲル ファーマシューティカルズ インコーポレーティッド | 脂質を主材料とする担体に内封された、不溶性小分子治療剤の製剤 |
WO2007070843A2 (en) * | 2005-12-15 | 2007-06-21 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for oral administration |
US20070142287A1 (en) * | 2005-12-20 | 2007-06-21 | Biomed Solutions, Llc | Compositions And Methods For Treatment Of Cancer |
US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
DK1973406T3 (da) | 2005-12-28 | 2014-06-23 | Advanced Bionutrition Corp | Fremføringsmiddel til probiotiske bakerier omfattende en tør blanding af polysaccharider, saccharider, polyoler i glasform |
GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
JP2010511713A (ja) * | 2006-12-05 | 2010-04-15 | ランデック コーポレイション | 薬物送達 |
US20090246155A1 (en) * | 2006-12-05 | 2009-10-01 | Landec Corporation | Compositions and methods for personal care |
US8399007B2 (en) * | 2006-12-05 | 2013-03-19 | Landec Corporation | Method for formulating a controlled-release pharmaceutical formulation |
US20100004124A1 (en) * | 2006-12-05 | 2010-01-07 | David Taft | Systems and methods for delivery of materials for agriculture and aquaculture |
US20090263346A1 (en) * | 2006-12-05 | 2009-10-22 | David Taft | Systems and methods for delivery of drugs |
EP2117354B1 (en) | 2006-12-18 | 2018-08-08 | Advanced BioNutrition Corp. | A dry food product containing live probiotic |
EP3391874A3 (en) * | 2007-02-12 | 2019-04-24 | Particle Sciences, Inc. | Delivery devices containing encapsulated and/or particle- bound active pharmaceutical ingredients |
US20090148498A1 (en) * | 2007-05-14 | 2009-06-11 | Sustained Nano Systems Llc | Controlled release implantable dispensing device and method |
US20080292680A1 (en) * | 2007-05-14 | 2008-11-27 | Sustained Nano Systems Llc | Hypercompressed polymer particles for controlled release ophthalmic medications |
US8071119B2 (en) * | 2007-05-14 | 2011-12-06 | Sustained Nano Systems Llc | Controlled release implantable dispensing device and method |
US8101274B2 (en) * | 2007-06-11 | 2012-01-24 | Spedden Richard H | Solid state membranes with surface-embedded glycosylated amphiphilic molecules and micelles formed therefrom |
FR2919188B1 (fr) * | 2007-07-27 | 2010-02-26 | Proteins & Peptides Man | Complexes entre un polymere amphiphile et une proteine osteogenique appartenant a la famille des bmps |
US8067028B2 (en) * | 2007-08-13 | 2011-11-29 | Confluent Surgical Inc. | Drug delivery device |
US8114883B2 (en) * | 2007-12-04 | 2012-02-14 | Landec Corporation | Polymer formulations for delivery of bioactive materials |
ES2718612T3 (es) | 2007-12-20 | 2019-07-03 | Evonik Corp | Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual |
CN102159163B (zh) * | 2008-07-14 | 2014-09-10 | 波利皮得有限公司 | 持续释放药物载体组合物 |
US9861154B2 (en) | 2008-07-18 | 2018-01-09 | Biomod Collection Inc. | Articles of manufacture releasing an active ingredient |
CN102176882A (zh) | 2008-08-07 | 2011-09-07 | 生物活性外科公司 | 医疗器械和植入物的干细胞捕获和固定涂层 |
AU2009295886A1 (en) * | 2008-09-24 | 2010-04-01 | Resilux | Incorporation of thermo-resistant and/or pressure-resistant organisms in materials |
CA2756883C (en) | 2009-03-27 | 2018-01-09 | Advanced Bionutrition Corp. | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
US20120135017A1 (en) | 2009-05-26 | 2012-05-31 | Moti Harel | Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making |
JP5738856B2 (ja) | 2009-07-14 | 2015-06-24 | ポリピッド リミテッド | 徐放性薬物担体組成物 |
JP5860409B2 (ja) * | 2010-01-19 | 2016-02-16 | ポリピッド リミテッド | 徐放性核酸マトリックス組成物 |
US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
WO2011094469A2 (en) | 2010-01-28 | 2011-08-04 | Advanced Bionutrition Corporation | Dry glassy composition comprising a bioactive material |
AU2011256259A1 (en) | 2010-05-17 | 2012-11-08 | Novaer Holdings, Inc. | Drug delivery devices for delivery of ocular therapeutic agents |
CN103140145B (zh) | 2010-08-13 | 2014-08-20 | 高级生物营养公司 | 用于生物材料的干的贮存稳定用组合物 |
WO2012037193A2 (en) | 2010-09-17 | 2012-03-22 | Brassica Protection Products Llc | Formulations for treatment with glucosinolate |
ITMI20111050A1 (it) | 2011-06-10 | 2012-12-11 | Sevecom Spa | Uso di emulsionanti in associazione con oleine vegetali in un alimento per animali. |
US20140271861A1 (en) * | 2011-07-27 | 2014-09-18 | Polypid Ltd. | Matrix compositions for controlled release of peptide and polypeptide molecules |
CN105287431A (zh) * | 2014-05-30 | 2016-02-03 | 中国科学院过程工程研究所 | 一种载活性药物的聚合物脂质球及其制备方法 |
PE20170138A1 (es) | 2014-07-21 | 2017-03-16 | Sevecom Spa | Emulsionante en polvo para alimentos para animales |
AU2015301399B2 (en) | 2014-08-14 | 2018-11-08 | Brown University | Compositions for stabilizing and delivering proteins |
CN108347982A (zh) | 2015-07-29 | 2018-07-31 | 高级生物营养公司 | 用于特殊饮食用途的稳定的干燥益生菌组合物 |
US10327935B2 (en) * | 2016-07-21 | 2019-06-25 | Cook Medical Technologies Llc | Stent graft with internal constraining mechanism |
US11690807B2 (en) | 2018-05-24 | 2023-07-04 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
EP3801378A4 (en) | 2018-05-24 | 2022-02-23 | Celanese EVA Performance Polymers LLC | IMPLANTABLE DEVICE FOR THE DELAYED RELEASE OF A MACROMOLECULAR DRUG COMPOUND |
CN112094580A (zh) * | 2020-09-01 | 2020-12-18 | 杭州曦茂新材料科技有限公司 | 一种树脂防腐涂料及其生产方法 |
WO2024069235A2 (en) | 2022-09-30 | 2024-04-04 | Sixfold Bioscience Ltd. | Compositions containing oligonucleotides with theranostic applications |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2409283A (en) | 1943-04-21 | 1946-10-15 | James L Hudson | Coupling for plastic tubes |
US3022209A (en) | 1956-11-23 | 1962-02-20 | Phillips Petroleum Co | Method of welding butted pipe sections of polyethylene to form a reinforced joint |
US3643805A (en) | 1970-01-20 | 1972-02-22 | Abcor Water Management Co Inc | A membrane system which includes a tube sheet for securing supported membrane tubes therein |
US3683960A (en) | 1970-11-19 | 1972-08-15 | Jerry Kirsch | Block manifold for fluid control systems and method of making the same |
GB1390379A (en) | 1972-06-28 | 1975-04-09 | Serck Industries Ltd | Method of manufacturing hollow articles eg heat exchangers |
US3776001A (en) | 1973-01-16 | 1973-12-04 | Kimberly Clark Co | Self-lubricating compound for use in hygienic and medical applications, and suppositories made therefrom |
US4070044A (en) | 1976-01-22 | 1978-01-24 | Phillips Petroleum Company | Polymer pipe connection and method to make it |
US4312687A (en) | 1980-12-15 | 1982-01-26 | Chevron Research Company | Solar collector headers |
US4818542A (en) | 1983-11-14 | 1989-04-04 | The University Of Kentucky Research Foundation | Porous microspheres for drug delivery and methods for making same |
US4615114A (en) | 1984-03-12 | 1986-10-07 | Asea Electric, Incorporated | Method of manufacturing molded buswork for power distribution systems |
US4730458A (en) * | 1986-09-26 | 1988-03-15 | The United States Of America As Represented By The United States Department Of Energy | Thermal electric vapor trap arrangement and method |
US5012052A (en) * | 1988-03-22 | 1991-04-30 | Indiana University Foundation | Isotope-ratio-monitoring gas chromatography-mass spectrometry apparatus and method |
US5447341A (en) | 1988-06-13 | 1995-09-05 | Metzeler Automotive Profiles Gmbh | Molder rubber hose branch |
CA1328550C (en) | 1988-09-19 | 1994-04-19 | Yoshinori Umezawa | Method of fabricating pipe units |
AU645003B2 (en) | 1988-11-08 | 1994-01-06 | Takeda Chemical Industries Ltd. | Sustained release preparations |
US5342628A (en) | 1990-10-11 | 1994-08-30 | Applied Medical Research, Inc. | Drug diffusion polymer system and method |
US5287758A (en) * | 1991-01-26 | 1994-02-22 | Behringwerke Ag | Temperature controlled pipette tube |
US5335944A (en) | 1991-03-25 | 1994-08-09 | Toyoda Gosei Co., Ltd. | Hose coupling structure |
JPH0538769A (ja) | 1991-07-19 | 1993-02-19 | Mitsutoyo Jushi Kk | ブロー成形管の端部に厚肉フランジを射出成形する方法 |
JPH0570793A (ja) * | 1991-09-10 | 1993-03-23 | Nissei Baadeishie Kk | 脂質の粒状組成物 |
FR2693249B1 (fr) | 1992-07-03 | 1994-09-16 | Hutchinson | Procédé de raccordement de tubes ou tuyaux, raccords et dispositifs analogues obtenus par sa mise en Óoeuvre. |
JP3266656B2 (ja) * | 1992-08-18 | 2002-03-18 | 日清ファルマ株式会社 | ビタミン含浸粒状物およびその製造方法 |
AU683022B2 (en) | 1992-09-10 | 1997-10-30 | Children's Medical Center Corporation | Biodegradable polymer matrices for sustained delivery of local anesthetic agents |
US5411300A (en) | 1993-03-16 | 1995-05-02 | Toyoda Gosei Co., Ltd. | Hose connecting assembly |
FR2710265B1 (fr) | 1993-09-22 | 1995-10-20 | Adir | Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs. |
DE4337492C2 (de) | 1993-11-03 | 1999-06-02 | Joerg Michael Dr Re Schierholz | Verfahren zur Inkorporierung lipophiler pharmazeutisch wirksamer Substanzen in weiche Kontaktlinsen zur Erstellung ophthalmologischer kontrollierter Freisetzungssysteme mittels diffusionskontrollierter Sorption |
US5626862A (en) | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
US6333021B1 (en) | 1994-11-22 | 2001-12-25 | Bracco Research S.A. | Microcapsules, method of making and their use |
US5942253A (en) | 1995-10-12 | 1999-08-24 | Immunex Corporation | Prolonged release of GM-CSF |
DE69713278T2 (de) | 1996-02-07 | 2003-02-06 | Anthony Joseph Cesaroni | Verbinden von rohren aus thermoplastischen polymeren |
US5762961A (en) * | 1996-02-09 | 1998-06-09 | Quadrant Holdings Cambridge Ltd. | Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof |
JP3544604B2 (ja) * | 1996-12-16 | 2004-07-21 | 株式会社荏原製作所 | 切替式トラップ装置 |
US5874064A (en) * | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
US5855913A (en) | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
US5837221A (en) | 1996-07-29 | 1998-11-17 | Acusphere, Inc. | Polymer-lipid microencapsulated gases for use as imaging agents |
DE19631001C1 (de) * | 1996-08-01 | 1997-12-18 | Testo Gmbh & Co | Kondensatabscheider |
KR0181252B1 (ko) * | 1996-12-31 | 1999-03-20 | 박원훈 | 에멀젼 방법에 의한 다공성 매트릭스형 서방성 제제의 제조방법 |
US5895695A (en) | 1997-03-28 | 1999-04-20 | Rowley; William W. | Crosslinked overmolded plumbing tubes |
JP3347977B2 (ja) * | 1997-07-02 | 2002-11-20 | フリヂスター株式会社 | 液体循環型熱電冷却・加熱装置 |
US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
US6540926B2 (en) * | 1997-10-02 | 2003-04-01 | David Paul Goodrich | Filter assembly |
US6423345B2 (en) * | 1998-04-30 | 2002-07-23 | Acusphere, Inc. | Matrices formed of polymer and hydrophobic compounds for use in drug delivery |
US6096178A (en) * | 1998-08-24 | 2000-08-01 | Aviv Amirav | Electrolyzer device for the operation of flame ionization detectors |
US6101815A (en) * | 1998-11-09 | 2000-08-15 | General Electric Company | Thermo-electrical dehumidifier |
US6490879B1 (en) * | 2000-09-27 | 2002-12-10 | Assist International Marketing, Inc. | Water generating machine |
US6427449B1 (en) * | 2000-12-15 | 2002-08-06 | Solid State Cooling Systems | Compact volatile organic compound removal system |
US6370884B1 (en) * | 2001-03-30 | 2002-04-16 | Maher I. Kelada | Thermoelectric fluid cooling cartridge |
-
1999
- 1999-02-22 US US09/255,179 patent/US6423345B2/en not_active Expired - Lifetime
- 1999-03-08 NZ NZ508470A patent/NZ508470A/xx not_active IP Right Cessation
- 1999-03-08 CA CA002329875A patent/CA2329875C/en not_active Expired - Fee Related
- 1999-03-08 DK DK99911269T patent/DK1073422T3/da active
- 1999-03-08 KR KR1020007012030A patent/KR100703051B1/ko not_active IP Right Cessation
- 1999-03-08 JP JP2000546758A patent/JP5153032B2/ja not_active Expired - Fee Related
- 1999-03-08 EP EP99911269A patent/EP1073422B1/en not_active Expired - Lifetime
- 1999-03-08 BR BR9910340-0A patent/BR9910340A/pt not_active IP Right Cessation
- 1999-03-08 WO PCT/US1999/005187 patent/WO1999056731A1/en active IP Right Grant
- 1999-03-08 IL IL13925299A patent/IL139252A0/xx active IP Right Grant
- 1999-03-08 DE DE69930240T patent/DE69930240T2/de not_active Expired - Lifetime
- 1999-03-08 CN CNB99806372XA patent/CN1201729C/zh not_active Expired - Fee Related
- 1999-03-08 AU AU29954/99A patent/AU746696B2/en not_active Ceased
- 1999-03-08 PT PT99911269T patent/PT1073422E/pt unknown
- 1999-03-08 AT AT99911269T patent/ATE319433T1/de active
- 1999-03-08 PL PL343691A patent/PL196159B1/pl unknown
- 1999-03-08 MX MXPA00010566A patent/MXPA00010566A/es not_active IP Right Cessation
- 1999-03-08 ES ES99911269T patent/ES2259472T3/es not_active Expired - Lifetime
-
2000
- 2000-10-24 IL IL139252A patent/IL139252A/en not_active IP Right Cessation
- 2000-10-27 NO NO20005452A patent/NO324895B1/no not_active IP Right Cessation
- 2000-12-06 US US09/731,412 patent/US7052719B2/en not_active Expired - Fee Related
- 2000-12-06 US US09/730,694 patent/US7160557B2/en not_active Expired - Fee Related
-
2003
- 2003-03-05 US US10/383,264 patent/US6689390B2/en not_active Expired - Fee Related
-
2006
- 2006-12-29 US US11/617,935 patent/US20070104656A1/en not_active Abandoned
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