WO2000041481A3 - Arzneiformen mit gesteuerter freisetzung, enthaltend gut wasserlösliche wirkstoffe - Google Patents

Arzneiformen mit gesteuerter freisetzung, enthaltend gut wasserlösliche wirkstoffe Download PDF

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Publication number
WO2000041481A3
WO2000041481A3 PCT/EP2000/000053 EP0000053W WO0041481A3 WO 2000041481 A3 WO2000041481 A3 WO 2000041481A3 EP 0000053 W EP0000053 W EP 0000053W WO 0041481 A3 WO0041481 A3 WO 0041481A3
Authority
WO
WIPO (PCT)
Prior art keywords
water
controlled release
active substances
containing active
easily dissolve
Prior art date
Application number
PCT/EP2000/000053
Other languages
English (en)
French (fr)
Other versions
WO2000041481A2 (de
Inventor
Joerg Rosenberg
Joerg Neumann
Christiane Vollgraf
Ulrich Reinhold
Original Assignee
Knoll Ag
Joerg Rosenberg
Joerg Neumann
Christiane Vollgraf
Ulrich Reinhold
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag, Joerg Rosenberg, Joerg Neumann, Christiane Vollgraf, Ulrich Reinhold filed Critical Knoll Ag
Priority to EP00904879A priority Critical patent/EP1140030A2/de
Priority to JP2000593105A priority patent/JP2002534443A/ja
Priority to CA002359381A priority patent/CA2359381A1/en
Publication of WO2000041481A2 publication Critical patent/WO2000041481A2/de
Publication of WO2000041481A3 publication Critical patent/WO2000041481A3/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Arzneiform, enthaltend einen Wirkstoff mit einer Wasserlöslichkeit gemäss USP 23 von bis zu 30 in einer Matrix auf Basis von Acrylat-Polymeren, wobei die Arzneiform durch Schmelzextrusion erhalten wird.
PCT/EP2000/000053 1999-01-14 2000-01-07 Arzneiformen mit gesteuerter freisetzung, enthaltend gut wasserlösliche wirkstoffe WO2000041481A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP00904879A EP1140030A2 (de) 1999-01-14 2000-01-07 Arzneiformen mit gesteuerter freisetzung, enthaltend gut wasserlösliche wirkstoffe
JP2000593105A JP2002534443A (ja) 1999-01-14 2000-01-07 十分に水溶性の作用物質を含有している制御された放出を有する剤形
CA002359381A CA2359381A1 (en) 1999-01-14 2000-01-07 Medicament forms having controlled release and containing active substances which easily dissolve in water

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19901040.4 1999-01-14
DE19901040A DE19901040A1 (de) 1999-01-14 1999-01-14 Arzneiformen mit gesteuerter Freisetzung, enthaltend gut wasserlösliche Wirkstoffe

Publications (2)

Publication Number Publication Date
WO2000041481A2 WO2000041481A2 (de) 2000-07-20
WO2000041481A3 true WO2000041481A3 (de) 2000-09-28

Family

ID=7894143

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/000053 WO2000041481A2 (de) 1999-01-14 2000-01-07 Arzneiformen mit gesteuerter freisetzung, enthaltend gut wasserlösliche wirkstoffe

Country Status (5)

Country Link
EP (1) EP1140030A2 (de)
JP (1) JP2002534443A (de)
CA (1) CA2359381A1 (de)
DE (1) DE19901040A1 (de)
WO (1) WO2000041481A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2818552B1 (fr) * 2000-12-26 2003-02-07 Servier Lab Compositions pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine
US8481565B2 (en) 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
SG169334A1 (en) * 2006-01-21 2011-03-30 Abbott Gmbh & Co Kg Dosage form and method for the delivery of drugs of abuse
AU2007275033A1 (en) * 2006-07-21 2008-01-24 Lab International Srl Hydrophobic abuse deterrent delivery system
JP2011511782A (ja) 2008-02-12 2011-04-14 アボット・ラボラトリーズ 長期放出性ヒドロコドンアセトアミノフェンならびにその関連方法および用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073379A (en) * 1988-09-07 1991-12-17 Basf Aktiengesellschaft Continuous preparation of solid pharmaceutical forms
EP0661045A1 (de) * 1992-09-18 1995-07-05 Yamanouchi Pharmaceutical Co. Ltd. Hydrogelzubereitung mit verzögerter freisetzung
WO1996029061A1 (de) * 1995-03-21 1996-09-26 Basf Aktiengesellschaft Verfahren zur herstellung von wirkstoffzubereitungen in form einer festen lösung des wirkstoffs in einer polymermatrix sowie mit diesem verfahren hergestellte wirkstoffzubereitungen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073379A (en) * 1988-09-07 1991-12-17 Basf Aktiengesellschaft Continuous preparation of solid pharmaceutical forms
EP0661045A1 (de) * 1992-09-18 1995-07-05 Yamanouchi Pharmaceutical Co. Ltd. Hydrogelzubereitung mit verzögerter freisetzung
WO1996029061A1 (de) * 1995-03-21 1996-09-26 Basf Aktiengesellschaft Verfahren zur herstellung von wirkstoffzubereitungen in form einer festen lösung des wirkstoffs in einer polymermatrix sowie mit diesem verfahren hergestellte wirkstoffzubereitungen

Also Published As

Publication number Publication date
WO2000041481A2 (de) 2000-07-20
EP1140030A2 (de) 2001-10-10
CA2359381A1 (en) 2000-07-20
JP2002534443A (ja) 2002-10-15
DE19901040A1 (de) 2000-07-20

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