NO20004900L - Substituerte indolalkansyrer - Google Patents

Substituerte indolalkansyrer

Info

Publication number
NO20004900L
NO20004900L NO20004900A NO20004900A NO20004900L NO 20004900 L NO20004900 L NO 20004900L NO 20004900 A NO20004900 A NO 20004900A NO 20004900 A NO20004900 A NO 20004900A NO 20004900 L NO20004900 L NO 20004900L
Authority
NO
Norway
Prior art keywords
alkanoic acids
substituted indole
indole alkanoic
substituted
acids
Prior art date
Application number
NO20004900A
Other languages
English (en)
Norwegian (no)
Other versions
NO20004900D0 (no
Inventor
Michael L Jones
David Gunn
John Howard Jones
Michael V Van Zandt
Original Assignee
Inst For Pharm Discovery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst For Pharm Discovery Inc filed Critical Inst For Pharm Discovery Inc
Publication of NO20004900D0 publication Critical patent/NO20004900D0/no
Publication of NO20004900L publication Critical patent/NO20004900L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
NO20004900A 1998-03-31 2000-09-29 Substituerte indolalkansyrer NO20004900L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8014398P 1998-03-31 1998-03-31
PCT/US1999/007116 WO1999050268A2 (fr) 1998-03-31 1999-03-31 Acides indolalcanoiques substitues

Publications (2)

Publication Number Publication Date
NO20004900D0 NO20004900D0 (no) 2000-09-29
NO20004900L true NO20004900L (no) 2000-10-17

Family

ID=22155536

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004900A NO20004900L (no) 1998-03-31 2000-09-29 Substituerte indolalkansyrer

Country Status (29)

Country Link
US (9) US6214991B1 (fr)
EP (1) EP1066283B1 (fr)
JP (2) JP3494990B2 (fr)
KR (1) KR100584650B1 (fr)
CN (1) CN1205207C (fr)
AP (1) AP2000001929A0 (fr)
AT (1) ATE269861T1 (fr)
AU (1) AU774929B2 (fr)
BG (1) BG65446B1 (fr)
BR (1) BR9909358A (fr)
CA (1) CA2383983C (fr)
CZ (1) CZ300706B6 (fr)
DE (1) DE69918278T2 (fr)
EE (1) EE200000573A (fr)
ES (1) ES2224632T3 (fr)
HU (1) HUP0101672A3 (fr)
ID (1) ID27884A (fr)
IL (2) IL138711A0 (fr)
MX (1) MXPA02003122A (fr)
NO (1) NO20004900L (fr)
NZ (1) NZ507172A (fr)
OA (1) OA11622A (fr)
PL (1) PL201645B1 (fr)
SK (1) SK7522001A3 (fr)
TR (1) TR200002869T2 (fr)
TW (1) TWI243163B (fr)
WO (1) WO1999050268A2 (fr)
YU (1) YU59600A (fr)
ZA (1) ZA200005577B (fr)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
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KR100584650B1 (ko) * 1998-03-31 2006-05-30 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 치환된 인돌알칸산
TNSN99224A1 (fr) * 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
CA2378047A1 (fr) * 1999-07-15 2001-01-25 Methvin Isaac Composes heterocycliques destines au traitement de la migraine
WO2001064205A2 (fr) * 2000-03-02 2001-09-07 The Institutes For Pharmaceutical Discovery, Llc Compositions contenant un acide indol-alkanoique substitue et inhibiteur d'enzyme de conversion de l'angiotensine
WO2001085983A2 (fr) * 2000-05-09 2001-11-15 The Institute For Pharmaceutical Discovery Llc Procede pour tester des composes convenant au traitement de complications diabetiques
CA2433100A1 (fr) 2000-12-27 2002-07-04 Helmut Haning Derives de l'indole utilises comme ligands de recepteurs de la thyroide
DK1397130T3 (da) 2001-06-20 2007-11-12 Wyeth Corp Substituerede indolsyrederivater som inhibitorer af plasminogenaktivatorinhibitor-1 (PAI-1)
TWI224101B (en) 2001-06-20 2004-11-21 Wyeth Corp Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
WO2003061657A1 (fr) 2002-01-18 2003-07-31 Aryx Therapeutics Antagonistes du recepteur 5-ht3 et leurs procedes d'utilisation
KR20050026002A (ko) * 2002-07-26 2005-03-14 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 치환된 인돌알칸산 유도체 및 이를 함유하는 당뇨 합병증치료용 제형
CA2395871A1 (fr) * 2002-07-26 2004-01-26 The Institutes For Pharmaceutical Discovery, Llc Derives d'acides indoles-alcanoiques substitues et formulations contenant ces derniers pour utilisation dans le traitement des complications liees au diabete
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EP1569900B1 (fr) 2002-12-10 2006-06-28 Wyeth Derives substitues d'acides 3-carbonyl- indol-1-yl acetique comme inhibiteurs-1dd'activation plasminogenique
JP2006510673A (ja) 2002-12-10 2006-03-30 ワイス プラスミノゲンアクティベータインヒビター１（ｐａｉ−１）のインヒビターとしての、アリール、アリールオキシ、および、アルキルオキシ置換１ｈ−インドール−３−イルグリオキシル酸誘導体
WO2004052856A1 (fr) 2002-12-10 2004-06-24 Wyeth Derives d'acide indole oxo-acetyl amino acetique substitue comme inhibiteurs d'inhibiteur-1 de l'activateur du plasminogene (pai-1)
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US7442805B2 (en) 2003-09-25 2008-10-28 Wyeth Substituted sulfonamide-indoles
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US7582773B2 (en) 2003-09-25 2009-09-01 Wyeth Substituted phenyl indoles
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TNSN99224A1 (fr) 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
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Also Published As

Publication number Publication date
OA11622A (en) 2004-09-16
EP1066283B1 (fr) 2004-06-23
US20030018053A1 (en) 2003-01-23
US6426344B2 (en) 2002-07-30
US20120270912A1 (en) 2012-10-25
NZ507172A (en) 2003-10-31
PL201645B1 (pl) 2009-04-30
CZ300706B6 (cs) 2009-07-22
JP2002509931A (ja) 2002-04-02
AU774929B2 (en) 2004-07-15
US20100137301A1 (en) 2010-06-03
JP3494990B2 (ja) 2004-02-09
US20010016661A1 (en) 2001-08-23
KR20010042330A (ko) 2001-05-25
KR100584650B1 (ko) 2006-05-30
NO20004900D0 (no) 2000-09-29
US8163932B2 (en) 2012-04-24
BG65446B1 (bg) 2008-08-29
BR9909358A (pt) 2000-12-12
EP1066283A2 (fr) 2001-01-10
AU3459599A (en) 1999-10-18
US6214991B1 (en) 2001-04-10
CZ20003607A3 (cs) 2001-03-14
US7105514B2 (en) 2006-09-12
IL138711A0 (en) 2001-10-31
PL348244A1 (en) 2002-05-20
IL138711A (en) 2006-09-05
CN1205207C (zh) 2005-06-08
MXPA02003122A (es) 2004-04-21
TWI243163B (en) 2005-11-11
US20100324039A1 (en) 2010-12-23
US7304079B2 (en) 2007-12-04
US20070093530A1 (en) 2007-04-26
BG104819A (en) 2001-05-31
EE200000573A (et) 2002-04-15
ES2224632T3 (es) 2005-03-01
DE69918278T2 (de) 2005-07-14
US6730794B2 (en) 2004-05-04
ZA200005577B (en) 2002-02-11
WO1999050268A2 (fr) 1999-10-07
DE69918278D1 (de) 2004-07-29
ATE269861T1 (de) 2004-07-15
US20080214540A1 (en) 2008-09-04
WO1999050268A3 (fr) 1999-12-16
CA2383983A1 (fr) 1999-10-07
US20040235933A1 (en) 2004-11-25
CN1296485A (zh) 2001-05-23
HUP0101672A2 (hu) 2002-04-29
YU59600A (sh) 2002-12-10
JP2003155274A (ja) 2003-05-27
SK7522001A3 (en) 2002-02-05
AP2000001929A0 (en) 2000-09-30
US7659269B2 (en) 2010-02-09
TR200002869T2 (tr) 2000-12-21
ID27884A (id) 2001-05-03
CA2383983C (fr) 2009-09-29
HUP0101672A3 (en) 2002-05-28

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