NO180445C - 2-(4-hydroksypiperidino)-1-alkanol-derivater som anti-iskemiske midler - Google Patents

2-(4-hydroksypiperidino)-1-alkanol-derivater som anti-iskemiske midler

Info

Publication number
NO180445C
NO180445C NO940144A NO940144A NO180445C NO 180445 C NO180445 C NO 180445C NO 940144 A NO940144 A NO 940144A NO 940144 A NO940144 A NO 940144A NO 180445 C NO180445 C NO 180445C
Authority
NO
Norway
Prior art keywords
hydroxypiperidino
ischemic agents
alkanol derivatives
alkanol
derivatives
Prior art date
Application number
NO940144A
Other languages
English (en)
Norwegian (no)
Other versions
NO940144L (no
NO180445B (no
NO940144D0 (no
Inventor
Jr Willard Mckowan Welch
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO940144L publication Critical patent/NO940144L/no
Publication of NO940144D0 publication Critical patent/NO940144D0/no
Publication of NO180445B publication Critical patent/NO180445B/no
Publication of NO180445C publication Critical patent/NO180445C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO940144A 1991-07-17 1994-01-14 2-(4-hydroksypiperidino)-1-alkanol-derivater som anti-iskemiske midler NO180445C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73157791A 1991-07-17 1991-07-17
PCT/US1992/004973 WO1993002052A1 (en) 1991-07-17 1992-06-19 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents

Publications (4)

Publication Number Publication Date
NO940144L NO940144L (no) 1994-01-14
NO940144D0 NO940144D0 (no) 1994-01-14
NO180445B NO180445B (no) 1997-01-13
NO180445C true NO180445C (no) 1997-04-23

Family

ID=24940103

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940144A NO180445C (no) 1991-07-17 1994-01-14 2-(4-hydroksypiperidino)-1-alkanol-derivater som anti-iskemiske midler

Country Status (22)

Country Link
EP (1) EP0594729A1 (enrdf_load_stackoverflow)
JP (1) JP2571904B2 (enrdf_load_stackoverflow)
KR (1) KR0165003B1 (enrdf_load_stackoverflow)
CN (1) CN1043759C (enrdf_load_stackoverflow)
AU (1) AU655840B2 (enrdf_load_stackoverflow)
BR (1) BR9206272A (enrdf_load_stackoverflow)
CA (1) CA2113568A1 (enrdf_load_stackoverflow)
CZ (1) CZ284133B6 (enrdf_load_stackoverflow)
EG (1) EG20048A (enrdf_load_stackoverflow)
FI (2) FI940192L (enrdf_load_stackoverflow)
HU (1) HUT70528A (enrdf_load_stackoverflow)
IE (1) IE922311A1 (enrdf_load_stackoverflow)
IL (1) IL102473A (enrdf_load_stackoverflow)
MX (1) MX9204190A (enrdf_load_stackoverflow)
NO (1) NO180445C (enrdf_load_stackoverflow)
NZ (1) NZ243580A (enrdf_load_stackoverflow)
PL (1) PL169884B1 (enrdf_load_stackoverflow)
PT (1) PT100689B (enrdf_load_stackoverflow)
RU (1) RU2065859C1 (enrdf_load_stackoverflow)
TW (1) TW201732B (enrdf_load_stackoverflow)
WO (1) WO1993002052A1 (enrdf_load_stackoverflow)
ZA (1) ZA925306B (enrdf_load_stackoverflow)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
ATE150751T1 (de) * 1992-10-30 1997-04-15 Pfizer Neuroprotektive 3,4-dihydro-2(1h)-chinolone
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
US6978166B2 (en) 1994-10-07 2005-12-20 Saint Louis University System for use in displaying images of a body part
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
CA2220649C (en) * 1996-12-03 2007-02-13 F. Hoffmann-La Roche Ag 4-hydroxy-piperidine derivatives
WO2000061558A1 (fr) * 1999-04-09 2000-10-19 Mochida Pharmaceutical Co., Ltd. Remedes pour douleurs neurogenes
TWI254043B (en) * 1999-06-08 2006-05-01 Hoffmann La Roche Ethanesulfonyl-piperidine derivatives having good affinity to N-methyl-D-aspartate (NMDA) receptor
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
CA2386441A1 (en) 1999-10-29 2001-05-03 Merck Sharp & Dohme Limited Method to treat pain utilizing benzimidazole nmda/nr2b antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
WO2002068409A1 (en) 2001-02-23 2002-09-06 Merck & Co., Inc. N-substituted nonaryl-heterocyclic nmda/nr2b antagonists
JP2005511478A (ja) 2001-04-03 2005-04-28 メルク エンド カムパニー インコーポレーテッド N−置換非アリール複素環アミジル系nmda/nr2b拮抗薬
JP4544999B2 (ja) 2002-11-25 2010-09-15 持田製薬株式会社 4−ヒドロキシピペリジン誘導体を有効成分とする呼吸器疾患治療剤
CA2541162A1 (en) * 2003-10-08 2005-04-21 Pfizer Inc. Fused lactam compounds
TWI409289B (zh) 2010-09-02 2013-09-21 Taiwan Union Technology Corp 由氮氧雜環化合物所製得之聚合物之穩態溶液及其製法與用途
BR112022025900A2 (pt) * 2020-06-23 2023-01-10 Biohaven Therapeutics Ltd Formulações tópicas de (1s)-1-fenil-2-piridin-2-iletanamina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2546166B1 (fr) * 1983-05-19 1985-10-25 Synthelabo Enantiomeres du erythro (benzyl-4 piperidino)-2 (hydroxy-4 ou benzyloxy-4 phenyl)-1 propanol, leur preparation et leur application en therapeutique
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
EP0398578B1 (en) * 1989-05-17 1997-03-12 Pfizer Inc. 2-piperidino-1-alkanol derivatives as antiischemic agents
PL169267B1 (pl) * 1990-05-10 1996-06-28 Pfizer Sposób wytwarzania nowej racemicznej lub optycznie czynnej pochodnej indolu PL PL PL PL PL PL

Also Published As

Publication number Publication date
EG20048A (en) 1997-03-27
FI981956A7 (fi) 1998-09-11
FI940192A7 (fi) 1994-01-14
JP2571904B2 (ja) 1997-01-16
CZ400892A3 (en) 1994-03-16
AU2322592A (en) 1993-02-23
CN1068566A (zh) 1993-02-03
CA2113568A1 (en) 1993-02-04
WO1993002052A1 (en) 1993-02-04
AU655840B2 (en) 1995-01-12
IL102473A0 (en) 1993-01-14
MX9204190A (es) 1993-01-01
EP0594729A1 (en) 1994-05-04
PT100689B (pt) 1999-06-30
TW201732B (enrdf_load_stackoverflow) 1993-03-11
FI981956L (fi) 1998-09-11
NO940144L (no) 1994-01-14
NO180445B (no) 1997-01-13
CN1043759C (zh) 1999-06-23
NZ243580A (en) 1994-10-26
JPH06504293A (ja) 1994-05-19
BR9206272A (pt) 1995-04-11
FI940192A0 (fi) 1994-01-14
FI981956A0 (fi) 1998-09-11
PT100689A (pt) 1993-10-29
ZA925306B (en) 1994-01-17
NO940144D0 (no) 1994-01-14
HUT70528A (en) 1995-10-30
IE922311A1 (en) 1993-01-27
FI940192L (fi) 1994-01-14
RU2065859C1 (ru) 1996-08-27
KR0165003B1 (en) 1999-01-15
HU9400136D0 (en) 1994-05-30
IL102473A (en) 1997-07-13
PL169884B1 (pl) 1996-09-30
CZ284133B6 (cs) 1998-08-12

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN DECEMBER 2001