NO180445C - 2- (4-hydroxypiperidino) -1-alkanol derivatives as anti-ischemic agents - Google Patents

2- (4-hydroxypiperidino) -1-alkanol derivatives as anti-ischemic agents

Info

Publication number
NO180445C
NO180445C NO940144A NO940144A NO180445C NO 180445 C NO180445 C NO 180445C NO 940144 A NO940144 A NO 940144A NO 940144 A NO940144 A NO 940144A NO 180445 C NO180445 C NO 180445C
Authority
NO
Norway
Prior art keywords
hydroxypiperidino
ischemic agents
alkanol derivatives
alkanol
derivatives
Prior art date
Application number
NO940144A
Other languages
Norwegian (no)
Other versions
NO940144D0 (en
NO180445B (en
NO940144L (en
Inventor
Jr Willard Mckowan Welch
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO940144D0 publication Critical patent/NO940144D0/en
Publication of NO940144L publication Critical patent/NO940144L/en
Publication of NO180445B publication Critical patent/NO180445B/en
Publication of NO180445C publication Critical patent/NO180445C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO940144A 1991-07-17 1994-01-14 2- (4-hydroxypiperidino) -1-alkanol derivatives as anti-ischemic agents NO180445C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73157791A 1991-07-17 1991-07-17
PCT/US1992/004973 WO1993002052A1 (en) 1991-07-17 1992-06-19 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents

Publications (4)

Publication Number Publication Date
NO940144D0 NO940144D0 (en) 1994-01-14
NO940144L NO940144L (en) 1994-01-14
NO180445B NO180445B (en) 1997-01-13
NO180445C true NO180445C (en) 1997-04-23

Family

ID=24940103

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940144A NO180445C (en) 1991-07-17 1994-01-14 2- (4-hydroxypiperidino) -1-alkanol derivatives as anti-ischemic agents

Country Status (22)

Country Link
EP (1) EP0594729A1 (en)
JP (1) JP2571904B2 (en)
KR (1) KR0165003B1 (en)
CN (1) CN1043759C (en)
AU (1) AU655840B2 (en)
BR (1) BR9206272A (en)
CA (1) CA2113568A1 (en)
CZ (1) CZ284133B6 (en)
EG (1) EG20048A (en)
FI (2) FI940192A0 (en)
HU (1) HUT70528A (en)
IE (1) IE922311A1 (en)
IL (1) IL102473A (en)
MX (1) MX9204190A (en)
NO (1) NO180445C (en)
NZ (1) NZ243580A (en)
PL (1) PL169884B1 (en)
PT (1) PT100689B (en)
RU (1) RU2065859C1 (en)
TW (1) TW201732B (en)
WO (1) WO1993002052A1 (en)
ZA (1) ZA925306B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
CZ280669B6 (en) * 1992-10-30 1996-03-13 Pfizer Inc. Derivatives of 3,4-dihydro-2(1h)-quinolone and pharmaceutical composition based thereon
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610736B (en) 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
CA2369695A1 (en) * 1999-04-09 2000-10-19 Manabu Itoh Agent for treating neuropathic pain
WO2001030330A2 (en) 1999-10-29 2001-05-03 Merck Sharp & Dohme Limited Method to treat pain utilizing benzimidazole nmda/nr2b antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US7217716B2 (en) 2001-02-23 2007-05-15 Merck & Co., Inc. N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists
WO2002080928A1 (en) 2001-04-03 2002-10-17 Merck & Co., Inc. N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists
CA2507509A1 (en) 2002-11-25 2004-06-10 Mochida Pharmaceutical Co., Ltd. Therapeutic agent for respiratory disease containing 4-hydroxypiperidine derivative as active ingredient
JP2007508288A (en) * 2003-10-08 2007-04-05 ファイザー株式会社 Condensed lactam compounds
TWI409289B (en) 2010-09-02 2013-09-21 Taiwan Union Technology Corp Stable solution of the polymer prepared from n,o-heterocycles and its preparinging method and use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2546166B1 (en) * 1983-05-19 1985-10-25 Synthelabo ENANTIOMERS OF ERYTHRO (BENZYL-4 PIPERIDINO) -2 (HYDROXY-4 OR BENZYLOXY-4 PHENYL) -1 PROPANOL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2640266B2 (en) * 1988-07-12 1992-07-10 Synthelabo INDOLONES-2, QUINOLEINONES-2, BENZO (B) AZEPINONES-2 AND BENZIMIDAZOLONES-2 DERIVATIVES OF (HYDROXY-1 PIPERIDINYL-2 ALKYL), THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
EP0398578B1 (en) * 1989-05-17 1997-03-12 Pfizer Inc. 2-piperidino-1-alkanol derivatives as antiischemic agents
DK0554247T3 (en) * 1990-05-10 2000-08-07 Pfizer Neuroprotective indolone and related derivatives

Also Published As

Publication number Publication date
IL102473A0 (en) 1993-01-14
NZ243580A (en) 1994-10-26
JPH06504293A (en) 1994-05-19
BR9206272A (en) 1995-04-11
ZA925306B (en) 1994-01-17
KR0165003B1 (en) 1999-01-15
MX9204190A (en) 1993-01-01
CZ284133B6 (en) 1998-08-12
PT100689B (en) 1999-06-30
PL169884B1 (en) 1996-09-30
EP0594729A1 (en) 1994-05-04
HUT70528A (en) 1995-10-30
NO940144D0 (en) 1994-01-14
NO180445B (en) 1997-01-13
AU2322592A (en) 1993-02-23
HU9400136D0 (en) 1994-05-30
FI981956A (en) 1998-09-11
IE922311A1 (en) 1993-01-27
FI981956A0 (en) 1998-09-11
JP2571904B2 (en) 1997-01-16
FI940192A (en) 1994-01-14
NO940144L (en) 1994-01-14
FI940192A0 (en) 1994-01-14
WO1993002052A1 (en) 1993-02-04
CN1043759C (en) 1999-06-23
EG20048A (en) 1997-03-27
PT100689A (en) 1993-10-29
IL102473A (en) 1997-07-13
TW201732B (en) 1993-03-11
CZ400892A3 (en) 1994-03-16
AU655840B2 (en) 1995-01-12
RU2065859C1 (en) 1996-08-27
CA2113568A1 (en) 1993-02-04
CN1068566A (en) 1993-02-03

Similar Documents

Publication Publication Date Title
NO180445C (en) 2- (4-hydroxypiperidino) -1-alkanol derivatives as anti-ischemic agents
IS4208A (en) 3- (tetrazolyl-benzyl) amino-piperadidine derivatives
DK0712304T3 (en) Tissue materials exhibiting elastic-like behavior
FI924982A (en) FRYSTORKAT PREPARAT SOM INNEHAOLLER MONOKLONAL MOTKROPP
MX9205145A (en) NEW DERIVATIVES HETEROCICLICOS.
DK0516349T3 (en) 2-hydroxy-2-phenylethylamine derivatives as beta-3-adrenoceptor agonists
NO922182L (en) CRYSTALLINIC OXATATOLAN DERIVATIVES
FI921182A (en) VELANGUMMI SOM SNABBT HYDRATISERAS
DK0551048T3 (en) 2-Imidazone-5-one and 2-imidazoline-5-thione derivatives as fungicides
NO920157L (en) HETEROCYCLIC HYDROXYLAMINES
DE69216260D1 (en) Piperidine derivatives
DE69209099D1 (en) Sulfonamide derivatives
FI930342A (en) PENTAPEPTIDER SOM REGLERAR IMMUN- OCH NERVSYSTEM
FI931015A0 (en) 2- (2-SUBSTITUERADE PYRROLIDINYLTIO) CARBEN PENEMDERIVAT
FI941681A0 (en) thioformamide derivatives
FI953518A (en) Novel substituted thiosemicarbazone derivatives
DE69227554D1 (en) INDOLINOSPIROBENZOPYRAN DERIVATIVES
ATE169214T1 (en) PSYCHOACTIVE PROPARGYLAMIN DERIVATIVES
NO951299D0 (en) Polyamine derivatives as anti-cytomegaloviral agents
FI914768A (en) FOER STOEDMURAR LAEMPAD STAOLPROFIL MED KANTIG SAMMANFOGNING SOM ARBETSOEPPNING
NO941294L (en) Thioformamide derivative
BG97241A (en) TRIAZOLPYRIMIDINE DERIVATIVES
NO303283B1 (en) Substituted benzene derivatives
SE9102303D0 (en) MAINTAIN FOR TAKRAECKE
BR1100452A (en) Biphenylmethylimidazole derivatives

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN DECEMBER 2001