FI940192A0 - 2- (4-hydroxypiperidino) -1-alkanol derivatives as anti-ischemic agents - Google Patents

2- (4-hydroxypiperidino) -1-alkanol derivatives as anti-ischemic agents

Info

Publication number
FI940192A0
FI940192A0 FI940192A FI940192A FI940192A0 FI 940192 A0 FI940192 A0 FI 940192A0 FI 940192 A FI940192 A FI 940192A FI 940192 A FI940192 A FI 940192A FI 940192 A0 FI940192 A0 FI 940192A0
Authority
FI
Finland
Prior art keywords
hydroxypiperidino
ischemic agents
alkanol derivatives
alkanol
derivatives
Prior art date
Application number
FI940192A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI940192A (en
Inventor
Jr Willard Mckowan Welch
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI940192A0 publication Critical patent/FI940192A0/en
Publication of FI940192A publication Critical patent/FI940192A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI940192A 1991-07-17 1994-01-14 2- (4-hydroxypiperidino) -1-alkonol derivatives as anesthetics FI940192A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73157791A 1991-07-17 1991-07-17
PCT/US1992/004973 WO1993002052A1 (en) 1991-07-17 1992-06-19 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents

Publications (2)

Publication Number Publication Date
FI940192A0 true FI940192A0 (en) 1994-01-14
FI940192A FI940192A (en) 1994-01-14

Family

ID=24940103

Family Applications (2)

Application Number Title Priority Date Filing Date
FI940192A FI940192A (en) 1991-07-17 1994-01-14 2- (4-hydroxypiperidino) -1-alkonol derivatives as anesthetics
FI981956A FI981956A (en) 1991-07-17 1998-09-11 2- (4-hydroxypiperidino) -1-alkanol derivatives as antihypertensives

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI981956A FI981956A (en) 1991-07-17 1998-09-11 2- (4-hydroxypiperidino) -1-alkanol derivatives as antihypertensives

Country Status (22)

Country Link
EP (1) EP0594729A1 (en)
JP (1) JP2571904B2 (en)
KR (1) KR0165003B1 (en)
CN (1) CN1043759C (en)
AU (1) AU655840B2 (en)
BR (1) BR9206272A (en)
CA (1) CA2113568A1 (en)
CZ (1) CZ284133B6 (en)
EG (1) EG20048A (en)
FI (2) FI940192A (en)
HU (1) HUT70528A (en)
IE (1) IE922311A1 (en)
IL (1) IL102473A (en)
MX (1) MX9204190A (en)
NO (1) NO180445C (en)
NZ (1) NZ243580A (en)
PL (1) PL169884B1 (en)
PT (1) PT100689B (en)
RU (1) RU2065859C1 (en)
TW (1) TW201732B (en)
WO (1) WO1993002052A1 (en)
ZA (1) ZA925306B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
DE69309297T2 (en) * 1992-10-30 1997-07-03 Pfizer NEUROPROTECTIVE 3,4-DIHYDRO-2 (1H) -CHINOLONE
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
AU3676100A (en) * 1999-04-09 2000-11-14 Mochida Pharmaceutical Co., Ltd. Remedies for neuropathic pain
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
AU1153601A (en) 1999-10-29 2001-05-08 Merck Sharp & Dohme Limited Method to treat pain utilizing benzimidazole NMDA NR2B antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
EP1379520B2 (en) 2001-02-23 2014-04-09 Merck Sharp & Dohme Corp. N-substituted nonaryl-heterocyclic nmda/nr2b antagonists
CA2443108A1 (en) 2001-04-03 2002-10-17 Merck & Co. Inc. N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists
EP1568688B1 (en) 2002-11-25 2011-08-31 Mochida Pharmaceutical Co., Ltd. Therapeutic agent for respiratory disease containing 4-hydroxypiperidine derivative as active ingredient
WO2005035523A1 (en) * 2003-10-08 2005-04-21 Pfizer Japan Inc. Fused lactam compounds
TWI409289B (en) 2010-09-02 2013-09-21 Taiwan Union Technology Corp Stable solution of the polymer prepared from n,o-heterocycles and its preparinging method and use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2546166B1 (en) * 1983-05-19 1985-10-25 Synthelabo ENANTIOMERS OF ERYTHRO (BENZYL-4 PIPERIDINO) -2 (HYDROXY-4 OR BENZYLOXY-4 PHENYL) -1 PROPANOL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2640266B2 (en) * 1988-07-12 1992-07-10 Synthelabo INDOLONES-2, QUINOLEINONES-2, BENZO (B) AZEPINONES-2 AND BENZIMIDAZOLONES-2 DERIVATIVES OF (HYDROXY-1 PIPERIDINYL-2 ALKYL), THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
EP0398578B1 (en) * 1989-05-17 1997-03-12 Pfizer Inc. 2-piperidino-1-alkanol derivatives as antiischemic agents
ES2146578T3 (en) * 1990-05-10 2000-08-16 Pfizer NEUROPROTECTIVE INDOLONE AND RELATED DERIVATIVES.

Also Published As

Publication number Publication date
JP2571904B2 (en) 1997-01-16
AU2322592A (en) 1993-02-23
CZ400892A3 (en) 1994-03-16
JPH06504293A (en) 1994-05-19
IL102473A0 (en) 1993-01-14
BR9206272A (en) 1995-04-11
FI981956A0 (en) 1998-09-11
KR0165003B1 (en) 1999-01-15
IL102473A (en) 1997-07-13
NO180445C (en) 1997-04-23
HUT70528A (en) 1995-10-30
CZ284133B6 (en) 1998-08-12
CA2113568A1 (en) 1993-02-04
PT100689A (en) 1993-10-29
CN1043759C (en) 1999-06-23
ZA925306B (en) 1994-01-17
EG20048A (en) 1997-03-27
PT100689B (en) 1999-06-30
CN1068566A (en) 1993-02-03
NZ243580A (en) 1994-10-26
PL169884B1 (en) 1996-09-30
TW201732B (en) 1993-03-11
MX9204190A (en) 1993-01-01
IE922311A1 (en) 1993-01-27
WO1993002052A1 (en) 1993-02-04
NO940144L (en) 1994-01-14
RU2065859C1 (en) 1996-08-27
FI940192A (en) 1994-01-14
EP0594729A1 (en) 1994-05-04
HU9400136D0 (en) 1994-05-30
FI981956A (en) 1998-09-11
NO180445B (en) 1997-01-13
AU655840B2 (en) 1995-01-12
NO940144D0 (en) 1994-01-14

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