ZA925306B - 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents - Google Patents

2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents

Info

Publication number
ZA925306B
ZA925306B ZA925306A ZA925306A ZA925306B ZA 925306 B ZA925306 B ZA 925306B ZA 925306 A ZA925306 A ZA 925306A ZA 925306 A ZA925306 A ZA 925306A ZA 925306 B ZA925306 B ZA 925306B
Authority
ZA
South Africa
Prior art keywords
hydroxypiperidino
alkanol derivatives
antiischemic agents
antiischemic
agents
Prior art date
Application number
ZA925306A
Other languages
English (en)
Inventor
Willard Mckowan Welch Jr
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA925306B publication Critical patent/ZA925306B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA925306A 1991-07-17 1992-07-16 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents ZA925306B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73157791A 1991-07-17 1991-07-17

Publications (1)

Publication Number Publication Date
ZA925306B true ZA925306B (en) 1994-01-17

Family

ID=24940103

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925306A ZA925306B (en) 1991-07-17 1992-07-16 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents

Country Status (22)

Country Link
EP (1) EP0594729A1 (enrdf_load_stackoverflow)
JP (1) JP2571904B2 (enrdf_load_stackoverflow)
KR (1) KR0165003B1 (enrdf_load_stackoverflow)
CN (1) CN1043759C (enrdf_load_stackoverflow)
AU (1) AU655840B2 (enrdf_load_stackoverflow)
BR (1) BR9206272A (enrdf_load_stackoverflow)
CA (1) CA2113568A1 (enrdf_load_stackoverflow)
CZ (1) CZ284133B6 (enrdf_load_stackoverflow)
EG (1) EG20048A (enrdf_load_stackoverflow)
FI (2) FI940192L (enrdf_load_stackoverflow)
HU (1) HUT70528A (enrdf_load_stackoverflow)
IE (1) IE922311A1 (enrdf_load_stackoverflow)
IL (1) IL102473A (enrdf_load_stackoverflow)
MX (1) MX9204190A (enrdf_load_stackoverflow)
NO (1) NO180445C (enrdf_load_stackoverflow)
NZ (1) NZ243580A (enrdf_load_stackoverflow)
PL (1) PL169884B1 (enrdf_load_stackoverflow)
PT (1) PT100689B (enrdf_load_stackoverflow)
RU (1) RU2065859C1 (enrdf_load_stackoverflow)
TW (1) TW201732B (enrdf_load_stackoverflow)
WO (1) WO1993002052A1 (enrdf_load_stackoverflow)
ZA (1) ZA925306B (enrdf_load_stackoverflow)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
ATE150751T1 (de) * 1992-10-30 1997-04-15 Pfizer Neuroprotektive 3,4-dihydro-2(1h)-chinolone
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
US6978166B2 (en) 1994-10-07 2005-12-20 Saint Louis University System for use in displaying images of a body part
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) * 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
CA2220649C (en) * 1996-12-03 2007-02-13 F. Hoffmann-La Roche Ag 4-hydroxy-piperidine derivatives
WO2000061558A1 (fr) * 1999-04-09 2000-10-19 Mochida Pharmaceutical Co., Ltd. Remedes pour douleurs neurogenes
TWI254043B (en) * 1999-06-08 2006-05-01 Hoffmann La Roche Ethanesulfonyl-piperidine derivatives having good affinity to N-methyl-D-aspartate (NMDA) receptor
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
CA2386441A1 (en) 1999-10-29 2001-05-03 Merck Sharp & Dohme Limited Method to treat pain utilizing benzimidazole nmda/nr2b antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
WO2002068409A1 (en) 2001-02-23 2002-09-06 Merck & Co., Inc. N-substituted nonaryl-heterocyclic nmda/nr2b antagonists
JP2005511478A (ja) 2001-04-03 2005-04-28 メルク　エンド　カムパニー　インコーポレーテッド Ｎ−置換非アリール複素環アミジル系ｎｍｄａ／ｎｒ２ｂ拮抗薬
JP4544999B2 (ja) 2002-11-25 2010-09-15 持田製薬株式会社 ４−ヒドロキシピペリジン誘導体を有効成分とする呼吸器疾患治療剤
CA2541162A1 (en) * 2003-10-08 2005-04-21 Pfizer Inc. Fused lactam compounds
TWI409289B (zh) 2010-09-02 2013-09-21 Taiwan Union Technology Corp 由氮氧雜環化合物所製得之聚合物之穩態溶液及其製法與用途
BR112022025900A2 (pt) * 2020-06-23 2023-01-10 Biohaven Therapeutics Ltd Formulações tópicas de (1s)-1-fenil-2-piridin-2-iletanamina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2546166B1 (fr) * 1983-05-19 1985-10-25 Synthelabo Enantiomeres du erythro (benzyl-4 piperidino)-2 (hydroxy-4 ou benzyloxy-4 phenyl)-1 propanol, leur preparation et leur application en therapeutique
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
EP0398578B1 (en) * 1989-05-17 1997-03-12 Pfizer Inc. 2-piperidino-1-alkanol derivatives as antiischemic agents
PL169267B1 (pl) * 1990-05-10 1996-06-28 Pfizer Sposób wytwarzania nowej racemicznej lub optycznie czynnej pochodnej indolu PL PL PL PL PL PL

Also Published As

Publication number Publication date
EG20048A (en) 1997-03-27
FI981956A7 (fi) 1998-09-11
FI940192A7 (fi) 1994-01-14
JP2571904B2 (ja) 1997-01-16
NO180445C (no) 1997-04-23
CZ400892A3 (en) 1994-03-16
AU2322592A (en) 1993-02-23
CN1068566A (zh) 1993-02-03
CA2113568A1 (en) 1993-02-04
WO1993002052A1 (en) 1993-02-04
AU655840B2 (en) 1995-01-12
IL102473A0 (en) 1993-01-14
MX9204190A (es) 1993-01-01
EP0594729A1 (en) 1994-05-04
PT100689B (pt) 1999-06-30
TW201732B (enrdf_load_stackoverflow) 1993-03-11
FI981956L (fi) 1998-09-11
NO940144L (no) 1994-01-14
NO180445B (no) 1997-01-13
CN1043759C (zh) 1999-06-23
NZ243580A (en) 1994-10-26
JPH06504293A (ja) 1994-05-19
BR9206272A (pt) 1995-04-11
FI940192A0 (fi) 1994-01-14
FI981956A0 (fi) 1998-09-11
PT100689A (pt) 1993-10-29
NO940144D0 (no) 1994-01-14
HUT70528A (en) 1995-10-30
IE922311A1 (en) 1993-01-27
FI940192L (fi) 1994-01-14
RU2065859C1 (ru) 1996-08-27
KR0165003B1 (en) 1999-01-15
HU9400136D0 (en) 1994-05-30
IL102473A (en) 1997-07-13
PL169884B1 (pl) 1996-09-30
CZ284133B6 (cs) 1998-08-12

Similar Documents

Publication Publication Date Title
IL102473A0 (en) 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents
GR3023621T3 (en) 3-Hydroxy-4-aryl-5-oxo-pyrazolin derivatives
PL307812A1 (en) Substituted thiazolydinone derivatives
EP0586537A4 (en) Substituted n-carboxyalkylpeptidyl derivatives as antidegenerative active agents
HU9203994D0 (en) Imidazo-pyridine derivatives
GB9100505D0 (en) Piperidine derivatives
HU9202768D0 (en) Cyano-phenyl-pyrrole derivatives
EP0438690A3 (en) Substituted pyrazolin derivatives
HU9303225D0 (en) Benzofurane derivatives
FI925295L (fi) Baenksystem foer kompositioner avsedda foer jordbruk
HU9202388D0 (en) Aryl-alkyl-amine derivatives
ZA92278B (en) 3-quinuclidine derivatives
EP0520435A3 (en) Dc-89 derivatives
ZA922976B (en) 4-Aryl-3-heteroarylureidoquinoline derivatives
GB9320940D0 (en) Substituted n-carboxyalkylpeptidyl derivatives as antidegenerative agents
GB2262739B (en) Benzofuranylimidazole derivatives
ZA92786B (en) Pyrimidinyl-and triazinylsalicyl-and-picolinylaldehyde derivatives
HU9300556D0 (en) Substituted phenyl-quinazoline derivatives
HU9200105D0 (en) Bipiridyl derivatives
EP0578560A3 (en) Amido-alcohol derivatives as psychotropic agents
IE901154L (en) Thioformamide derivatives
GB9110611D0 (en) Pyrrolo-pyriding derivatives
GB9106070D0 (en) Benzodioxanylimidazole derivatives
ZA924959B (en) Hydroisoquinoline derivatives
GB9119874D0 (en) 3-cylopropyl-prop-2-enamide derivatives