NO180445C - 2-(4-hydroksypiperidino)-1-alkanol-derivater som anti-iskemiske midler - Google Patents

2-(4-hydroksypiperidino)-1-alkanol-derivater som anti-iskemiske midler

Info

Publication number
NO180445C
NO180445C NO940144A NO940144A NO180445C NO 180445 C NO180445 C NO 180445C NO 940144 A NO940144 A NO 940144A NO 940144 A NO940144 A NO 940144A NO 180445 C NO180445 C NO 180445C
Authority
NO
Norway
Prior art keywords
hydroxypiperidino
ischemic agents
alkanol derivatives
alkanol
derivatives
Prior art date
Application number
NO940144A
Other languages
English (en)
Norwegian (no)
Other versions
NO940144D0 (no
NO940144L (no
NO180445B (no
Inventor
Jr Willard Mckowan Welch
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO940144D0 publication Critical patent/NO940144D0/no
Publication of NO940144L publication Critical patent/NO940144L/no
Publication of NO180445B publication Critical patent/NO180445B/no
Publication of NO180445C publication Critical patent/NO180445C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO940144A 1991-07-17 1994-01-14 2-(4-hydroksypiperidino)-1-alkanol-derivater som anti-iskemiske midler NO180445C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73157791A 1991-07-17 1991-07-17
PCT/US1992/004973 WO1993002052A1 (en) 1991-07-17 1992-06-19 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents

Publications (4)

Publication Number Publication Date
NO940144D0 NO940144D0 (no) 1994-01-14
NO940144L NO940144L (no) 1994-01-14
NO180445B NO180445B (no) 1997-01-13
NO180445C true NO180445C (no) 1997-04-23

Family

ID=24940103

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940144A NO180445C (no) 1991-07-17 1994-01-14 2-(4-hydroksypiperidino)-1-alkanol-derivater som anti-iskemiske midler

Country Status (22)

Country Link
EP (1) EP0594729A1 (cs)
JP (1) JP2571904B2 (cs)
KR (1) KR0165003B1 (cs)
CN (1) CN1043759C (cs)
AU (1) AU655840B2 (cs)
BR (1) BR9206272A (cs)
CA (1) CA2113568A1 (cs)
CZ (1) CZ284133B6 (cs)
EG (1) EG20048A (cs)
FI (2) FI981956A7 (cs)
HU (1) HUT70528A (cs)
IE (1) IE922311A1 (cs)
IL (1) IL102473A (cs)
MX (1) MX9204190A (cs)
NO (1) NO180445C (cs)
NZ (1) NZ243580A (cs)
PL (1) PL169884B1 (cs)
PT (1) PT100689B (cs)
RU (1) RU2065859C1 (cs)
TW (1) TW201732B (cs)
WO (1) WO1993002052A1 (cs)
ZA (1) ZA925306B (cs)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
JP2695292B2 (ja) * 1992-10-30 1997-12-24 フアイザー・インコーポレイテツド 神経保護性3,4−ジヒドロ−(1h)−キノロン化合物
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
US6978166B2 (en) 1994-10-07 2005-12-20 Saint Louis University System for use in displaying images of a body part
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610736B (en) 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
CA2220649C (en) * 1996-12-03 2007-02-13 F. Hoffmann-La Roche Ag 4-hydroxy-piperidine derivatives
EP1182193A4 (en) * 1999-04-09 2002-09-11 Mochida Pharm Co Ltd REMEDIES FOR NEUROGENIC PAIN
TWI254043B (en) * 1999-06-08 2006-05-01 Hoffmann La Roche Ethanesulfonyl-piperidine derivatives having good affinity to N-methyl-D-aspartate (NMDA) receptor
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
JP2003512422A (ja) 1999-10-29 2003-04-02 メルク シャープ エンド ドーム リミテッド ベンズイミダゾールnmda/nr2bアンタゴニストを使用する疼痛の治療方法
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
CZ20032258A3 (cs) 2001-02-23 2004-01-14 Merck & Co., Inc. N-substituované nearylové heterocyklické sloučeniny
EP1390034A4 (en) 2001-04-03 2005-07-13 Merck & Co Inc NMDA / NR2B NONARYL-HETEROCYCLO AMIDYL N-SUBSTITUTE ANTAGONISTS
EP1568688B1 (en) 2002-11-25 2011-08-31 Mochida Pharmaceutical Co., Ltd. Therapeutic agent for respiratory disease containing 4-hydroxypiperidine derivative as active ingredient
WO2005035523A1 (en) * 2003-10-08 2005-04-21 Pfizer Japan Inc. Fused lactam compounds
TWI409289B (zh) 2010-09-02 2013-09-21 Taiwan Union Technology Corp 由氮氧雜環化合物所製得之聚合物之穩態溶液及其製法與用途
MX2022016183A (es) * 2020-06-23 2023-02-13 Biohaven Therapeutics Ltd Formulaciones topicas de (1s)-1-fenil-2-piridin-2-iletanamina.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FR2546166B1 (fr) * 1983-05-19 1985-10-25 Synthelabo Enantiomeres du erythro (benzyl-4 piperidino)-2 (hydroxy-4 ou benzyloxy-4 phenyl)-1 propanol, leur preparation et leur application en therapeutique
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
ES2098248T3 (es) * 1989-05-17 1997-05-01 Pfizer Derivados de 2-piperidino-1-alcanoles como agentes antiisquemicos.
AU642994B2 (en) * 1990-05-10 1993-11-04 Pfizer Inc. Neuroprotective indolone and related derivatives

Also Published As

Publication number Publication date
NO940144D0 (no) 1994-01-14
PT100689B (pt) 1999-06-30
JP2571904B2 (ja) 1997-01-16
CN1068566A (zh) 1993-02-03
WO1993002052A1 (en) 1993-02-04
KR0165003B1 (en) 1999-01-15
HUT70528A (en) 1995-10-30
IE922311A1 (en) 1993-01-27
PT100689A (pt) 1993-10-29
RU2065859C1 (ru) 1996-08-27
CN1043759C (zh) 1999-06-23
CZ284133B6 (cs) 1998-08-12
FI940192A0 (fi) 1994-01-14
CA2113568A1 (en) 1993-02-04
AU655840B2 (en) 1995-01-12
NO940144L (no) 1994-01-14
PL169884B1 (pl) 1996-09-30
FI981956A0 (fi) 1998-09-11
FI940192L (fi) 1994-01-14
AU2322592A (en) 1993-02-23
MX9204190A (es) 1993-01-01
HU9400136D0 (en) 1994-05-30
NZ243580A (en) 1994-10-26
ZA925306B (en) 1994-01-17
EG20048A (en) 1997-03-27
IL102473A (en) 1997-07-13
EP0594729A1 (en) 1994-05-04
FI940192A7 (fi) 1994-01-14
FI981956L (fi) 1998-09-11
CZ400892A3 (en) 1994-03-16
NO180445B (no) 1997-01-13
JPH06504293A (ja) 1994-05-19
IL102473A0 (en) 1993-01-14
FI981956A7 (fi) 1998-09-11
BR9206272A (pt) 1995-04-11
TW201732B (cs) 1993-03-11

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN DECEMBER 2001