NO178923C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 24-homo-vitamin-D-derivater - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive 24-homo-vitamin-D-derivater

Info

Publication number
NO178923C
NO178923C NO904269A NO904269A NO178923C NO 178923 C NO178923 C NO 178923C NO 904269 A NO904269 A NO 904269A NO 904269 A NO904269 A NO 904269A NO 178923 C NO178923 C NO 178923C
Authority
NO
Norway
Prior art keywords
carbon atoms
derivatives
preparation
therapeutically active
analogous process
Prior art date
Application number
NO904269A
Other languages
English (en)
Norwegian (no)
Other versions
NO904269D0 (no
NO904269L (no
NO178923B (no
Inventor
Gerald Dr Kirsch
Guenter Dr Neef
Katica Schwarz
Matthias Dr Braeutigam
Ruth Dr Thieroff-Eckerdt
Petra Rach
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO904269D0 publication Critical patent/NO904269D0/no
Publication of NO904269L publication Critical patent/NO904269L/no
Publication of NO178923B publication Critical patent/NO178923B/no
Publication of NO178923C publication Critical patent/NO178923C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
NO904269A 1989-10-02 1990-10-01 Analogifremgangsmåte for fremstilling av terapeutisk aktive 24-homo-vitamin-D-derivater NO178923C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3933034A DE3933034A1 (de) 1989-10-02 1989-10-02 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung

Publications (4)

Publication Number Publication Date
NO904269D0 NO904269D0 (no) 1990-10-01
NO904269L NO904269L (no) 1991-04-03
NO178923B NO178923B (no) 1996-03-25
NO178923C true NO178923C (no) 1996-07-03

Family

ID=6390762

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904269A NO178923C (no) 1989-10-02 1990-10-01 Analogifremgangsmåte for fremstilling av terapeutisk aktive 24-homo-vitamin-D-derivater

Country Status (18)

Country Link
US (1) US5665716A (zh)
EP (1) EP0421561B1 (zh)
JP (1) JPH03246273A (zh)
CN (2) CN1031705C (zh)
AT (1) ATE103893T1 (zh)
AU (1) AU639717B2 (zh)
CA (1) CA2026671C (zh)
DD (1) DD299178A5 (zh)
DE (2) DE3933034A1 (zh)
DK (1) DK0421561T3 (zh)
ES (1) ES2052166T3 (zh)
FI (1) FI93643C (zh)
HU (1) HU210032B (zh)
IE (1) IE71227B1 (zh)
IL (1) IL95872A (zh)
NO (1) NO178923C (zh)
PT (1) PT95473B (zh)
ZA (1) ZA907876B (zh)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
DE4200783C2 (de) * 1992-01-10 1997-02-06 Schering Ag (5Z,7E,22E)-(1S,3R,24S)-24-Benzyl-9,10-secochola-5,7,10(19),22-tetraen-1,3,24-triol, Verfahren zur Herstellung und Pharmazeutische Präparate
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
DE4328217C2 (de) * 1993-08-21 1996-01-11 Lohmann Therapie Syst Lts Therapeutisches System zur Behandlung der Psoriasis
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
DE19935771A1 (de) 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
JP2004504295A (ja) * 2000-07-18 2004-02-12 ボーン　ケア　インターナショナル　インコーポレイテッド 安定化１α−ヒドロキシビタミンＤ
DE10156596A1 (de) * 2001-11-13 2003-05-28 Schering Ag Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
JP2005514929A (ja) * 2002-01-10 2005-05-26 テバ ファーマシューティカル インダストリーズ リミティド エピマービタミンｄ類似物の酵素による選択的なエステル化及び加溶媒分解及びエピマーの分離
WO2003106412A1 (en) * 2002-06-13 2003-12-24 Teva Pharmaceutical Industries Ltd. Epimerization of analogs of vitamin d
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
BRPI0715636A2 (pt) * 2006-08-29 2013-07-02 Teva Pharma composiÇÕes farmacologicamente ativas estÁveis incluindo compostos contendo vitamina d e corticosteràide com compatibilidade para ph baixo
US8716334B2 (en) * 2008-06-17 2014-05-06 Ben Gurion University Of The Negev Research And Development Authority Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
AU2010208323B2 (en) 2009-01-27 2016-03-10 Berg Llc Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (en) 2009-08-14 2019-05-22 Berg LLC Vitamin d3 and analogs thereof for treating alopecia
KR20160013201A (ko) 2013-05-29 2016-02-03 버그 엘엘씨 비타민 d를 이용한 화학요법 유발 탈모증의 예방 또는 완화
US10548908B2 (en) 2016-09-15 2020-02-04 Nostopharma, LLC Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986002078A1 (en) * 1984-10-04 1986-04-10 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
EP0245524B1 (en) * 1985-11-21 1991-04-17 Taisho Pharmaceutical Co. Ltd Vitamin d 3 derivative
US4847012A (en) * 1988-04-29 1989-07-11 Wisconsin Alumni Research Foundation Vitamin D related compounds and processes for their preparation
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives

Also Published As

Publication number Publication date
PT95473A (pt) 1991-06-25
AU639717B2 (en) 1993-08-05
EP0421561A2 (de) 1991-04-10
FI93643C (fi) 1995-05-10
ES2052166T3 (es) 1994-07-01
PT95473B (pt) 1997-07-31
CN1106666A (zh) 1995-08-16
HUT55751A (en) 1991-06-28
DD299178A5 (de) 1992-04-02
IE71227B1 (en) 1997-02-12
IL95872A (en) 1995-03-15
DE59005254D1 (de) 1994-05-11
NO904269D0 (no) 1990-10-01
US5665716A (en) 1997-09-09
DK0421561T3 (da) 1994-07-25
IE903520A1 (en) 1991-04-10
HU906284D0 (en) 1991-03-28
ZA907876B (en) 1992-04-29
EP0421561B1 (de) 1994-04-06
DE3933034A1 (de) 1991-04-11
JPH03246273A (ja) 1991-11-01
NO904269L (no) 1991-04-03
FI904850A0 (fi) 1990-10-02
CA2026671C (en) 1998-12-08
ATE103893T1 (de) 1994-04-15
CN1031705C (zh) 1996-05-01
FI93643B (fi) 1995-01-31
CA2026671A1 (en) 1991-04-03
HU210032B (en) 1995-01-30
NO178923B (no) 1996-03-25
CN1053103C (zh) 2000-06-07
AU6371590A (en) 1991-04-11
CN1051907A (zh) 1991-06-05
EP0421561A3 (en) 1991-06-12
IL95872A0 (en) 1991-07-18

Similar Documents

Publication Publication Date Title
NO178923C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive 24-homo-vitamin-D-derivater
FR2392971A1 (fr) Derives de l'acide prostanoique, leur preparation et medicament contenant ces substances
FR2429593A1 (fr) Medicaments contenant des derives d'imidazole
FR2360587A1 (fr) Nouveaux derives d'amino-alcoyl-furannes utiles comme medicaments
FR2367053A1 (fr) Nouveaux derives de phenoxy-amino-propanol, leur preparation et leur application en tant que medicaments
NL300396I1 (nl) Nieuwe derivaten met naftalinestructuren, werkwijze voor de bereiding ervan en de farmaceutische preparaten die deze bevatten
FR2373513A1 (fr) Nouveaux derives du naphtalene, leur preparation et leur application comme medicaments
FR2397403A1 (fr) Nouveaux derives de 1-acyl 2-cyano-aziridine, procede pour leur preparation et compositions pharmaceutiques contenant ces composes
FR2390448A1 (fr) Derives azido d'acide penicillanique utiles dans la preparation de medicaments
FR2649110B1 (fr) Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TNSN87012A1 (fr) Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
FR2443471A1 (fr) Derives du type thiazolidine de la progesterone utiles notamment comme precurseurs de medicaments antiacne et antiseborrhee
DE3371627D1 (en) Acetylsalicylic acid thioesters, a process for their preparation and pharmaceutical compositions containing them
FR2390424A1 (fr) Nouveaux derives d'amides de l'acide phenylacetique substitues, leur application en tant que medicament et leur application
FR2373285A1 (fr) Nouveaux derives du coenzyme b 12, procede de preparation et application a titre de medicaments de ces nouveaux produits
FR2396001A1 (fr) Derives a-acetyleniques et a-vinyliques d'amino-acides utiles comme medicaments et leur procede de preparation
FR2421181A1 (fr) Derives de substitution de spirooxazolidinone steroidienne, leur procede de preparation et compositions pharmaceutiques les contenant
FR2366289A1 (fr) Nouveaux derives de l'imidazo(5,1-a)isoquinoleine, leur preparation et leur application comme medicaments
FR2373514A1 (fr) Derives d'ammonium quaternaire de l'adamantane utiles notamment comme agents antimicrobiens et leur procede de preparation
FR2380272A1 (fr) Derives de la coumarine et d'indane-diode, utilisables comme medicament
FR2365555A1 (fr) Derives d'acide 2-(phenylalkylhydrazono)-propionique, procede pour leur preparation et medicaments contenant ces corps
FR2373528A1 (fr) Nouveaux derives de l'acide 1-aziridino-carboxylique, procede pour leur preparation et leur application comme medicaments immuno-stimulants
SE8903313L (sv) Nya 2-metoxikarbonyl-substituerade n,n'-di-(trimetoxibensoyl)-piperaziner, foerfarande foer framstaellning daerav och terapeutiska foereningar innehaallande dem
FR2386540A1 (fr) Derives d'acides furoyl- ou thenoyl- naphtyloxyalkylcarboxyliques, leur preparation et leur utilisation comme medicaments
GB995864A (en) New derivatives of hydantoins

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN APRIL 2001