ZA907876B - 24-homo vitamin d derivatives,process for their production and pharmaceutical preparations obtained therefrom - Google Patents

24-homo vitamin d derivatives,process for their production and pharmaceutical preparations obtained therefrom

Info

Publication number
ZA907876B
ZA907876B ZA907876A ZA907876A ZA907876B ZA 907876 B ZA907876 B ZA 907876B ZA 907876 A ZA907876 A ZA 907876A ZA 907876 A ZA907876 A ZA 907876A ZA 907876 B ZA907876 B ZA 907876B
Authority
ZA
South Africa
Prior art keywords
carbon atoms
derivatives
production
pharmaceutical preparations
obtained therefrom
Prior art date
Application number
ZA907876A
Other languages
English (en)
Inventor
Gerald Kirsch
Kirsch Gerald
Katica Schwarz
Schwarz Katica
Ruth Thieroff-Ekerdt
Thieroff-Ekerdt Ruth
Gunter Neef
Neef Gunter
Matthias Brautigam
Brautigam Matthias
Petra Rach
Rach Petra
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA907876B publication Critical patent/ZA907876B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA907876A 1989-10-02 1990-10-02 24-homo vitamin d derivatives,process for their production and pharmaceutical preparations obtained therefrom ZA907876B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3933034A DE3933034A1 (de) 1989-10-02 1989-10-02 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA907876B true ZA907876B (en) 1992-04-29

Family

ID=6390762

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA907876A ZA907876B (en) 1989-10-02 1990-10-02 24-homo vitamin d derivatives,process for their production and pharmaceutical preparations obtained therefrom

Country Status (18)

Country Link
US (1) US5665716A (zh)
EP (1) EP0421561B1 (zh)
JP (1) JPH03246273A (zh)
CN (2) CN1031705C (zh)
AT (1) ATE103893T1 (zh)
AU (1) AU639717B2 (zh)
CA (1) CA2026671C (zh)
DD (1) DD299178A5 (zh)
DE (2) DE3933034A1 (zh)
DK (1) DK0421561T3 (zh)
ES (1) ES2052166T3 (zh)
FI (1) FI93643C (zh)
HU (1) HU210032B (zh)
IE (1) IE71227B1 (zh)
IL (1) IL95872A (zh)
NO (1) NO178923C (zh)
PT (1) PT95473B (zh)
ZA (1) ZA907876B (zh)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
DE4200783C2 (de) * 1992-01-10 1997-02-06 Schering Ag (5Z,7E,22E)-(1S,3R,24S)-24-Benzyl-9,10-secochola-5,7,10(19),22-tetraen-1,3,24-triol, Verfahren zur Herstellung und Pharmazeutische Präparate
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
DE4328217C2 (de) * 1993-08-21 1996-01-11 Lohmann Therapie Syst Lts Therapeutisches System zur Behandlung der Psoriasis
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
DE19935771A1 (de) 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
IL153378A0 (en) * 2000-07-18 2003-07-06 Bone Care Internat Inc STABILIZED 1alpha-HYDROXY VITAMIN D
DE10156596A1 (de) * 2001-11-13 2003-05-28 Schering Ag Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
EP1470220B1 (en) * 2002-01-10 2011-10-05 Teva Pharmaceutical Industries, Ltd. Selective enzymatic esterification and solvolysis of epimeric vitamin d analog and separation of the epimers
CA2489593C (en) * 2002-06-13 2009-09-29 Teva Pharmaceutical Industries Ltd Epimerization of analogs of vitamin d
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
US20080064669A1 (en) * 2006-08-29 2008-03-13 Rakefet Cohen Stable pharmacologically active compositions including vitamin D-containing and corticosteroid compounds with low pH compatibility
EP2299809B1 (en) * 2008-06-17 2018-10-17 Ben Gurion University Of The Negev R&D Authority Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
CA2981549A1 (en) 2009-01-27 2010-08-05 Berg Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
SG10201404883YA (en) 2009-08-14 2014-10-30 Berg Llc Vitamin d3 and analogs thereof for treating alopecia
AU2014274099A1 (en) 2013-05-29 2015-12-24 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin D
US10548908B2 (en) 2016-09-15 2020-02-04 Nostopharma, LLC Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3590488T (de) * 1984-10-04 1986-10-09 Wisconsin Alumni Research Foundation, Madison, Wis. Vitamin D-Derivate und Verfahren zu deren Herstellung
EP0245524B1 (en) * 1985-11-21 1991-04-17 Taisho Pharmaceutical Co. Ltd Vitamin d 3 derivative
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US4847012A (en) * 1988-04-29 1989-07-11 Wisconsin Alumni Research Foundation Vitamin D related compounds and processes for their preparation
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives

Also Published As

Publication number Publication date
IE903520A1 (en) 1991-04-10
FI93643C (fi) 1995-05-10
US5665716A (en) 1997-09-09
ES2052166T3 (es) 1994-07-01
FI93643B (fi) 1995-01-31
IL95872A0 (en) 1991-07-18
CN1051907A (zh) 1991-06-05
DE3933034A1 (de) 1991-04-11
CN1031705C (zh) 1996-05-01
EP0421561A3 (en) 1991-06-12
EP0421561B1 (de) 1994-04-06
AU6371590A (en) 1991-04-11
EP0421561A2 (de) 1991-04-10
DD299178A5 (de) 1992-04-02
ATE103893T1 (de) 1994-04-15
DE59005254D1 (de) 1994-05-11
FI904850A0 (fi) 1990-10-02
PT95473A (pt) 1991-06-25
DK0421561T3 (da) 1994-07-25
NO178923C (no) 1996-07-03
HU210032B (en) 1995-01-30
NO178923B (no) 1996-03-25
NO904269D0 (no) 1990-10-01
IL95872A (en) 1995-03-15
JPH03246273A (ja) 1991-11-01
CA2026671C (en) 1998-12-08
PT95473B (pt) 1997-07-31
NO904269L (no) 1991-04-03
CN1106666A (zh) 1995-08-16
HU906284D0 (en) 1991-03-28
CN1053103C (zh) 2000-06-07
AU639717B2 (en) 1993-08-05
IE71227B1 (en) 1997-02-12
HUT55751A (en) 1991-06-28
CA2026671A1 (en) 1991-04-03

Similar Documents

Publication Publication Date Title
AU639717B2 (en) 24-homo vitamin d derivatives, process for their production and pharmaceutical preparations obtained therefrom
FR2392971A1 (fr) Derives de l'acide prostanoique, leur preparation et medicament contenant ces substances
FR2360587A1 (fr) Nouveaux derives d'amino-alcoyl-furannes utiles comme medicaments
FR2367053A1 (fr) Nouveaux derives de phenoxy-amino-propanol, leur preparation et leur application en tant que medicaments
FR2429593A1 (fr) Medicaments contenant des derives d'imidazole
FR2422643A1 (fr) Nouveaux derives d'imidazolidine, leur preparation et leur application comme medicaments
FR2416888A1 (fr) Nouveaux derives de phenyl-piperazine utiles comme medicaments
ES8606282A1 (es) Un procedimiento de preparar derivados de acidos quinolin- ynaftiridin-carboxilicos
ZA824438B (en) Novel 2-aryl-3,4-diazabicyclo-(4.n.o)alk-2-en-5-ones their preparation,and drugs containing them
FR2377367A1 (fr) Procede de preparation d'alcoxy-cetones
FR2421181A1 (fr) Derives de substitution de spirooxazolidinone steroidienne, leur procede de preparation et compositions pharmaceutiques les contenant
FR2373285A1 (fr) Nouveaux derives du coenzyme b 12, procede de preparation et application a titre de medicaments de ces nouveaux produits
SE8903312D0 (sv) New 2-carbonyl substituted n,n'-di-(trimethoxybenzol)piperazines, process for preparing the same and therapeutical compounds containing them
FR2361111A1 (fr) Nouveaux derives de 5-thiazole alkylamine, un procede pour leur preparation et leur application comme medicaments
FR2366289A1 (fr) Nouveaux derives de l'imidazo(5,1-a)isoquinoleine, leur preparation et leur application comme medicaments
HUT55033A (en) Process for producing aminooligohydroxy derivatives and pharmaceutical compositions comprising same
HUT57227A (en) 2'-dezamino-4'-desoxy-4'-amino-8-fluoro-anthracycline derivatives, process for producing them as well as pharmaceutical preparatives containing said compounds as active substance
HUT54682A (en) Process for producing 13-bromine- and 13,14-dibromine-ergoline derivatives and pharmaceutical preparatives containing these compounds
SE8903313L (sv) Nya 2-metoxikarbonyl-substituerade n,n'-di-(trimetoxibensoyl)-piperaziner, foerfarande foer framstaellning daerav och terapeutiska foereningar innehaallande dem
FR2453850A1 (fr) Nouveaux derives de 16-methoxy-16-methyl-prostaglandine e1 utiles notamment comme agents gastroprotecteurs et leur procede de preparation
FR2365555A1 (fr) Derives d'acide 2-(phenylalkylhydrazono)-propionique, procede pour leur preparation et medicaments contenant ces corps
HUT44802A (en) Process for producing pseudo-oligosaccharides and pharmaceutical compositions containing them
ATE29133T1 (de) Troponon-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.
FR2386540A1 (fr) Derives d'acides furoyl- ou thenoyl- naphtyloxyalkylcarboxyliques, leur preparation et leur utilisation comme medicaments
FR2415617A1 (fr) Derives de naphtalenone et analogues utiles comme medicaments et leur procede de preparation