NO178572C - Nye N-alkylenpiperidinoforbindelser og deres enantiomere og farmasöytiske blandinger inneholdende dem - Google Patents

Nye N-alkylenpiperidinoforbindelser og deres enantiomere og farmasöytiske blandinger inneholdende dem

Info

Publication number
NO178572C
NO178572C NO921733A NO921733A NO178572C NO 178572 C NO178572 C NO 178572C NO 921733 A NO921733 A NO 921733A NO 921733 A NO921733 A NO 921733A NO 178572 C NO178572 C NO 178572C
Authority
NO
Norway
Prior art keywords
group
alkyl
unsubstituted
carbon atoms
image
Prior art date
Application number
NO921733A
Other languages
English (en)
Norwegian (no)
Other versions
NO178572B (no
NO921733D0 (no
NO921733L (no
Inventor
Xavier Emonds-Alt
Serge Martinez
Vincenzo Proietto
Didier Van Broeck
Original Assignee
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Elf filed Critical Sanofi Elf
Publication of NO921733D0 publication Critical patent/NO921733D0/no
Publication of NO921733L publication Critical patent/NO921733L/no
Publication of NO178572B publication Critical patent/NO178572B/no
Publication of NO178572C publication Critical patent/NO178572C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Control Of Transmission Device (AREA)
NO921733A 1991-05-03 1992-04-30 Nye N-alkylenpiperidinoforbindelser og deres enantiomere og farmasöytiske blandinger inneholdende dem NO178572C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105486A FR2676054B1 (fr) 1991-05-03 1991-05-03 Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.

Publications (4)

Publication Number Publication Date
NO921733D0 NO921733D0 (no) 1992-04-30
NO921733L NO921733L (no) 1992-11-04
NO178572B NO178572B (no) 1996-01-15
NO178572C true NO178572C (no) 1996-04-24

Family

ID=9412519

Family Applications (1)

Application Number Title Priority Date Filing Date
NO921733A NO178572C (no) 1991-05-03 1992-04-30 Nye N-alkylenpiperidinoforbindelser og deres enantiomere og farmasöytiske blandinger inneholdende dem

Country Status (26)

Country Link
US (2) US5411971A (da)
EP (1) EP0515240B1 (da)
JP (1) JP3108719B2 (da)
KR (1) KR100244063B1 (da)
AT (1) ATE158574T1 (da)
AU (1) AU657321B2 (da)
BR (1) BR9201655A (da)
CA (1) CA2067924C (da)
CZ (1) CZ282919B6 (da)
DE (1) DE69222352T2 (da)
DK (1) DK0515240T3 (da)
ES (1) ES2109987T3 (da)
FI (1) FI103041B (da)
FR (1) FR2676054B1 (da)
GR (1) GR3025277T3 (da)
HU (1) HU213915B (da)
IE (1) IE921365A1 (da)
IL (1) IL101762A (da)
MX (1) MX9202026A (da)
MY (1) MY113018A (da)
NO (1) NO178572C (da)
NZ (1) NZ242584A (da)
RU (1) RU2089547C1 (da)
TW (1) TW201733B (da)
UA (1) UA26894C2 (da)
ZA (1) ZA923176B (da)

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US5512680A (en) 1993-02-26 1996-04-30 Sanofi Process for the preparation of an optically pure aminoalcohol
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GB9310713D0 (en) * 1993-05-24 1993-07-07 Zeneca Ltd Aryl substituted heterocycles
GB9317104D0 (en) 1993-08-17 1993-09-29 Zeneca Ltd Therapeutic heterocycles
GB9319534D0 (en) * 1993-09-22 1993-11-10 Boots Co Plc Therapeutic agents
AU7947594A (en) * 1993-10-27 1995-05-22 Merck Sharp & Dohme Limited Substituted amides as tachykinin antagonists
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GB9325074D0 (en) * 1993-12-07 1994-02-02 Zeneca Ltd Bicyclic heterocycles
US5589489A (en) * 1993-12-15 1996-12-31 Zeneca Limited Cyclic amide derivatives for treating asthma
FR2717478B1 (fr) * 1994-03-18 1996-06-21 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
FR2719311B1 (fr) * 1994-03-18 1998-06-26 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
FR2717477B1 (fr) * 1994-03-18 1996-06-07 Sanofi Elf Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
FR2717802B1 (fr) * 1994-03-25 1996-06-21 Sanofi Sa Nouveaux composés aromatiques, procédé pour leur préparation et compositions pharmaceutiques en contenant.
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US6008223A (en) * 1994-10-27 1999-12-28 Zeneca Limited Therapeutic compounds
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FR2729954B1 (fr) * 1995-01-30 1997-08-01 Sanofi Sa Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
GB9502644D0 (en) * 1995-02-10 1995-03-29 Zeneca Ltd Heterocyclic derivatives
GB9508786D0 (en) * 1995-04-29 1995-06-21 Zeneca Ltd Substituted heterocycles
US5654316A (en) * 1995-06-06 1997-08-05 Schering Corporation Piperidine derivatives as neurokinin antagonists
GB9516709D0 (en) * 1995-08-15 1995-10-18 Zeneca Ltd Medicament
FR2738819B1 (fr) * 1995-09-14 1997-12-05 Sanofi Sa Nouveaux composes antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant
GB9523526D0 (en) * 1995-11-17 1996-01-17 Zeneca Ltd Therapeutic compounds
HU224225B1 (hu) 1995-12-01 2005-06-28 Sankyo Co. Ltd. Tachikinin receptor antagonista hatású heterociklusos vegyületek, ezek előállítási eljárása és alkalmazásuk gyógyszerkészítmények előállítására
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
ES2177827T3 (es) * 1995-12-20 2002-12-16 Aventis Pharma Inc 4-(1h-bencimidazol-2-il)(1,4)diazepanes utiles para el tratamiento de enfermedades alergicas.
AU1608397A (en) 1996-02-02 1997-08-22 Zeneca Limited Heterocyclic compounds useful as pharmaceutical agents
GB9602166D0 (en) 1996-02-02 1996-04-03 Zeneca Ltd Aminoheterocyclic derivatives
CN1115341C (zh) * 1996-02-21 2003-07-23 阿温蒂斯药物公司 用于治疗过敏性疾病的新的取代的n-甲基-n-(4-(4-(1h-苯并咪唑-2-基氨基)哌啶-1-基)-2-(芳基)丁基)苯甲酰胺
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
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TR199900303T2 (xx) * 1996-08-14 1999-06-21 Zeneca Limited �kame edilmi� pirimidin t�revleri ve bunlar�n farmas�tik kullan�m�.
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
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US6316445B1 (en) 1998-05-15 2001-11-13 Aventis Pharmaceuticals Inc. Carboxy substituted acylic carboxamide derivatives
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GB9922521D0 (en) * 1998-10-07 1999-11-24 Zeneca Ltd Compounds
US6433174B1 (en) * 1998-12-16 2002-08-13 Nippon Kayaku Kabushiki Kaisha Process for producing novel naphthyridine derivatives
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
GB0004151D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004152D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
GB0004153D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
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Also Published As

Publication number Publication date
GR3025277T3 (en) 1998-02-27
TW201733B (da) 1993-03-11
HU9201459D0 (en) 1992-07-28
BR9201655A (pt) 1992-12-15
MY113018A (en) 2001-11-30
NO178572B (no) 1996-01-15
EP0515240A1 (fr) 1992-11-25
KR100244063B1 (ko) 2000-03-02
IL101762A0 (en) 1992-12-30
CS132892A3 (en) 1992-11-18
FR2676054A1 (fr) 1992-11-06
KR920021511A (ko) 1992-12-18
IE921365A1 (en) 1992-11-04
FR2676054B1 (fr) 1993-09-03
JP3108719B2 (ja) 2000-11-13
HUT65273A (en) 1994-05-02
US5411971A (en) 1995-05-02
AU1591892A (en) 1992-11-05
CA2067924C (en) 2004-03-30
ZA923176B (en) 1993-04-28
US5606065A (en) 1997-02-25
NO921733D0 (no) 1992-04-30
EP0515240B1 (fr) 1997-09-24
ES2109987T3 (es) 1998-02-01
UA26894C2 (uk) 1999-12-29
DE69222352D1 (de) 1997-10-30
NZ242584A (en) 1995-04-27
IL101762A (en) 1996-10-16
JPH05140103A (ja) 1993-06-08
DK0515240T3 (da) 1998-05-11
ATE158574T1 (de) 1997-10-15
RU2089547C1 (ru) 1997-09-10
FI921950A (fi) 1992-11-04
FI103041B1 (fi) 1999-04-15
FI921950A0 (fi) 1992-04-30
CZ282919B6 (cs) 1997-11-12
NO921733L (no) 1992-11-04
FI103041B (fi) 1999-04-15
DE69222352T2 (de) 1998-04-09
CA2067924A1 (en) 1992-11-04
HU213915B (en) 1997-11-28
AU657321B2 (en) 1995-03-09
MX9202026A (es) 1992-11-01

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