NO921733D0 - Nye n-alkylenpiperidinoforbindelser og deres enantiomere,fremgansmaate for fremstilling derav og farmasoeytiske blandinger inneholdende dem - Google Patents

Nye n-alkylenpiperidinoforbindelser og deres enantiomere,fremgansmaate for fremstilling derav og farmasoeytiske blandinger inneholdende dem

Info

Publication number
NO921733D0
NO921733D0 NO921733A NO921733A NO921733D0 NO 921733 D0 NO921733 D0 NO 921733D0 NO 921733 A NO921733 A NO 921733A NO 921733 A NO921733 A NO 921733A NO 921733 D0 NO921733 D0 NO 921733D0
Authority
NO
Norway
Prior art keywords
group
alkyl
unsubstituted
carbon atoms
image
Prior art date
Application number
NO921733A
Other languages
English (en)
Other versions
NO178572C (no
NO921733L (no
NO178572B (no
Inventor
Xavier Emonds-Alt
Serge Martinez
Vincenzo Proietto
Didier Van Broeck
Original Assignee
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Elf filed Critical Sanofi Elf
Publication of NO921733D0 publication Critical patent/NO921733D0/no
Publication of NO921733L publication Critical patent/NO921733L/no
Publication of NO178572B publication Critical patent/NO178572B/no
Publication of NO178572C publication Critical patent/NO178572C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
NO921733A 1991-05-03 1992-04-30 Nye N-alkylenpiperidinoforbindelser og deres enantiomere og farmasöytiske blandinger inneholdende dem NO178572C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105486A FR2676054B1 (fr) 1991-05-03 1991-05-03 Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.

Publications (4)

Publication Number Publication Date
NO921733D0 true NO921733D0 (no) 1992-04-30
NO921733L NO921733L (no) 1992-11-04
NO178572B NO178572B (no) 1996-01-15
NO178572C NO178572C (no) 1996-04-24

Family

ID=9412519

Family Applications (1)

Application Number Title Priority Date Filing Date
NO921733A NO178572C (no) 1991-05-03 1992-04-30 Nye N-alkylenpiperidinoforbindelser og deres enantiomere og farmasöytiske blandinger inneholdende dem

Country Status (26)

Country Link
US (2) US5411971A (no)
EP (1) EP0515240B1 (no)
JP (1) JP3108719B2 (no)
KR (1) KR100244063B1 (no)
AT (1) ATE158574T1 (no)
AU (1) AU657321B2 (no)
BR (1) BR9201655A (no)
CA (1) CA2067924C (no)
CZ (1) CZ282919B6 (no)
DE (1) DE69222352T2 (no)
DK (1) DK0515240T3 (no)
ES (1) ES2109987T3 (no)
FI (1) FI103041B1 (no)
FR (1) FR2676054B1 (no)
GR (1) GR3025277T3 (no)
HU (1) HU213915B (no)
IE (1) IE921365A1 (no)
IL (1) IL101762A (no)
MX (1) MX9202026A (no)
MY (1) MY113018A (no)
NO (1) NO178572C (no)
NZ (1) NZ242584A (no)
RU (1) RU2089547C1 (no)
TW (1) TW201733B (no)
UA (1) UA26894C2 (no)
ZA (1) ZA923176B (no)

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AU7947594A (en) * 1993-10-27 1995-05-22 Merck Sharp & Dohme Limited Substituted amides as tachykinin antagonists
GB9322643D0 (en) * 1993-11-03 1993-12-22 Zeneca Ltd Lactam derivatives
GB9325074D0 (en) * 1993-12-07 1994-02-02 Zeneca Ltd Bicyclic heterocycles
US5589489A (en) * 1993-12-15 1996-12-31 Zeneca Limited Cyclic amide derivatives for treating asthma
FR2719311B1 (fr) * 1994-03-18 1998-06-26 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
FR2717477B1 (fr) * 1994-03-18 1996-06-07 Sanofi Elf Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
FR2717478B1 (fr) * 1994-03-18 1996-06-21 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
FR2717802B1 (fr) * 1994-03-25 1996-06-21 Sanofi Sa Nouveaux composés aromatiques, procédé pour leur préparation et compositions pharmaceutiques en contenant.
GB9408872D0 (en) * 1994-05-03 1994-06-22 Zeneca Ltd Heterocyclic compounds
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IL115420A0 (en) * 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
FR2725986B1 (fr) * 1994-10-21 1996-11-29 Adir Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
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US5998444A (en) * 1995-10-24 1999-12-07 Zeneca Ltd. Piperidinyl compounds as NK1 or NK2 antagonists
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FR2729954B1 (fr) * 1995-01-30 1997-08-01 Sanofi Sa Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
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GB9502644D0 (en) * 1995-02-10 1995-03-29 Zeneca Ltd Heterocyclic derivatives
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US5654316A (en) * 1995-06-06 1997-08-05 Schering Corporation Piperidine derivatives as neurokinin antagonists
GB9516709D0 (en) * 1995-08-15 1995-10-18 Zeneca Ltd Medicament
FR2738819B1 (fr) * 1995-09-14 1997-12-05 Sanofi Sa Nouveaux composes antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant
GB9523526D0 (en) * 1995-11-17 1996-01-17 Zeneca Ltd Therapeutic compounds
HU224225B1 (hu) 1995-12-01 2005-06-28 Sankyo Co. Ltd. Tachikinin receptor antagonista hatású heterociklusos vegyületek, ezek előállítási eljárása és alkalmazásuk gyógyszerkészítmények előállítására
NZ325581A (en) * 1995-12-20 2000-03-27 Hoechst Marion Roussel Inc Substituted 4-(1h-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
GB9602166D0 (en) 1996-02-02 1996-04-03 Zeneca Ltd Aminoheterocyclic derivatives
WO1997028128A1 (en) 1996-02-02 1997-08-07 Zeneca Limited Heterocyclic compounds useful as pharmaceutical agents
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) * 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
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Also Published As

Publication number Publication date
AU657321B2 (en) 1995-03-09
EP0515240B1 (fr) 1997-09-24
FI103041B (fi) 1999-04-15
NO178572C (no) 1996-04-24
CA2067924C (en) 2004-03-30
CA2067924A1 (en) 1992-11-04
ES2109987T3 (es) 1998-02-01
ZA923176B (en) 1993-04-28
HU213915B (en) 1997-11-28
NZ242584A (en) 1995-04-27
AU1591892A (en) 1992-11-05
US5606065A (en) 1997-02-25
MX9202026A (es) 1992-11-01
FI103041B1 (fi) 1999-04-15
HUT65273A (en) 1994-05-02
FI921950A0 (fi) 1992-04-30
IE921365A1 (en) 1992-11-04
ATE158574T1 (de) 1997-10-15
GR3025277T3 (en) 1998-02-27
IL101762A0 (en) 1992-12-30
CS132892A3 (en) 1992-11-18
US5411971A (en) 1995-05-02
FR2676054A1 (fr) 1992-11-06
UA26894C2 (uk) 1999-12-29
HU9201459D0 (en) 1992-07-28
CZ282919B6 (cs) 1997-11-12
DE69222352D1 (de) 1997-10-30
NO921733L (no) 1992-11-04
KR100244063B1 (ko) 2000-03-02
IL101762A (en) 1996-10-16
FR2676054B1 (fr) 1993-09-03
RU2089547C1 (ru) 1997-09-10
NO178572B (no) 1996-01-15
EP0515240A1 (fr) 1992-11-25
FI921950A (fi) 1992-11-04
DK0515240T3 (da) 1998-05-11
MY113018A (en) 2001-11-30
JPH05140103A (ja) 1993-06-08
JP3108719B2 (ja) 2000-11-13
BR9201655A (pt) 1992-12-15
TW201733B (no) 1993-03-11
KR920021511A (ko) 1992-12-18
DE69222352T2 (de) 1998-04-09

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