NO912866L - Fremgangsmaate for fremstilling av 1-(substituert pyridinyl-amino)-1h-indol-5-yl-substituerte karbamater og deres mellomprodukter, og anvendelse som medikamenter. - Google Patents

Fremgangsmaate for fremstilling av 1-(substituert pyridinyl-amino)-1h-indol-5-yl-substituerte karbamater og deres mellomprodukter, og anvendelse som medikamenter.

Info

Publication number
NO912866L
NO912866L NO91912866A NO912866A NO912866L NO 912866 L NO912866 L NO 912866L NO 91912866 A NO91912866 A NO 91912866A NO 912866 A NO912866 A NO 912866A NO 912866 L NO912866 L NO 912866L
Authority
NO
Norway
Prior art keywords
loweralkyl
hydrogen
amino
substituted
indol
Prior art date
Application number
NO91912866A
Other languages
English (en)
Other versions
NO300132B1 (no
NO912866D0 (no
Inventor
Richard Charles Effland
Larry Davis
Gordon Edward Olsen
Joseph Thomas Klein
David Gordon Wettlaufer
Peter Allen Nemoto
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO912866D0 publication Critical patent/NO912866D0/no
Publication of NO912866L publication Critical patent/NO912866L/no
Publication of NO300132B1 publication Critical patent/NO300132B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO912866A 1990-07-23 1991-07-22 Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(substituerte pyridinylamino)-1H-indol-5-yl substituerte karbamater NO300132B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/555,890 US5102891A (en) 1990-07-23 1990-07-23 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates

Publications (3)

Publication Number Publication Date
NO912866D0 NO912866D0 (no) 1991-07-22
NO912866L true NO912866L (no) 1992-01-24
NO300132B1 NO300132B1 (no) 1997-04-14

Family

ID=24218998

Family Applications (1)

Application Number Title Priority Date Filing Date
NO912866A NO300132B1 (no) 1990-07-23 1991-07-22 Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(substituerte pyridinylamino)-1H-indol-5-yl substituerte karbamater

Country Status (23)

Country Link
US (1) US5102891A (no)
EP (1) EP0468401B1 (no)
JP (1) JP2564714B2 (no)
KR (1) KR100201515B1 (no)
AT (1) ATE171176T1 (no)
AU (1) AU639581B2 (no)
BR (1) BR1100534A (no)
CA (1) CA2047531C (no)
CZ (1) CZ283253B6 (no)
DE (1) DE69130196T2 (no)
DK (1) DK0468401T3 (no)
ES (1) ES2121761T3 (no)
FI (1) FI102067B (no)
HU (1) HUT58317A (no)
IE (1) IE912567A1 (no)
IL (1) IL98920A (no)
MX (1) MX9100342A (no)
NO (1) NO300132B1 (no)
NZ (1) NZ239038A (no)
PL (1) PL291185A1 (no)
PT (1) PT98413B (no)
SG (1) SG48059A1 (no)
ZA (1) ZA915723B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264442A (en) * 1990-08-13 1993-11-23 Hoechst-Roussel Pharmaceuticals Incorporated Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs
CZ284437B6 (cs) * 1991-04-17 1998-11-11 Hoechst Marion Roussel, Inc. Substituované (pyridinylamino)-benzisoxazoly a -benzo[b]thiofeny, způsob jejich přípravy farmaceutický prostředek obsahující tyto sloučeniny a použití těchto sloučenin
US5319096A (en) * 1992-04-03 1994-06-07 Hoechst-Roussel Pharmaceuticals Inc. (1H-indol-1-yl)-2-(amino) acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, pharmaceutical composition and use
US5459274A (en) * 1994-05-13 1995-10-17 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines
DE69715668T2 (de) * 1996-12-27 2003-07-31 Aventis Pharma Inc N-(pyridinylamino)isoindoline und verwandte verbindungen
US6004977A (en) * 1996-12-27 1999-12-21 Hoechst Marion Roussel, Inc. N-(pyridinylamino) isoindolines and related compounds
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
GT200500063A (es) * 2004-04-01 2005-10-14 Metodo para tratar la esquizofrenia y/o anormalidades glucoregulatorias
FR2888238B1 (fr) * 2005-07-07 2007-09-07 Servier Lab Nouveaux derives 1h-indole-pyridinecarboxamides et 1h-indole-piperidinecarboxamide, leur procede de preparation et les compositions pharceumatiques qui les contiennent.
EP2533645B1 (en) 2010-02-09 2016-07-27 The Johns Hopkins University Methods and compositions for improving cognitive function
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
EP2968220B1 (en) 2013-03-15 2021-05-05 Agenebio, Inc. Methods and compositions for improving cognitive function
US10925834B2 (en) 2015-05-22 2021-02-23 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US4970218A (en) * 1987-04-24 1990-11-13 Hoechst-Roussel Pharmaceuticals Inc. N-(pyridinyl)-1H-indol-1-amines
EP0287982B1 (en) * 1987-04-24 1994-12-07 Hoechst-Roussel Pharmaceuticals Incorporated N-(Pyridinyl)-1H-indol-1-amines, a process for their preparation and their use as medicaments
US4983615A (en) * 1989-06-28 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders
US5006537A (en) * 1989-08-02 1991-04-09 Hoechst-Roussel Pharmaceuticals, Inc. 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones
US4992448A (en) * 1989-10-24 1991-02-12 Hoechst-Roussel Pharmaceuticals Inc. Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders

Also Published As

Publication number Publication date
CA2047531C (en) 2003-01-07
ES2121761T3 (es) 1998-12-16
EP0468401A3 (en) 1992-07-29
ZA915723B (en) 1992-04-29
PT98413A (pt) 1992-05-29
FI102067B1 (fi) 1998-10-15
SG48059A1 (en) 1998-04-17
JPH04243878A (ja) 1992-08-31
JP2564714B2 (ja) 1996-12-18
EP0468401B1 (en) 1998-09-16
DE69130196T2 (de) 1999-04-01
DK0468401T3 (da) 1999-06-14
HUT58317A (en) 1992-02-28
EP0468401A2 (en) 1992-01-29
HU912450D0 (en) 1991-12-30
KR100201515B1 (ko) 1999-06-15
FI913502A0 (fi) 1991-07-19
IE912567A1 (en) 1992-01-29
FI102067B (fi) 1998-10-15
ATE171176T1 (de) 1998-10-15
KR920002585A (ko) 1992-02-28
DE69130196D1 (de) 1998-10-22
CA2047531A1 (en) 1992-01-24
BR1100534A (pt) 2000-03-14
US5102891A (en) 1992-04-07
PL291185A1 (en) 1993-04-05
NZ239038A (en) 1994-04-27
IL98920A (en) 1995-08-31
AU8121691A (en) 1992-01-30
CS228191A3 (en) 1992-02-19
FI913502A (fi) 1992-01-24
NO300132B1 (no) 1997-04-14
CZ283253B6 (cs) 1998-02-18
NO912866D0 (no) 1991-07-22
PT98413B (pt) 1999-01-29
MX9100342A (es) 1992-02-28
AU639581B2 (en) 1993-07-29

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