NO177932C - Analogifremgangsmåte ved fremstilling av terapeutisk aktive indenoindolforbindelser - Google Patents
Analogifremgangsmåte ved fremstilling av terapeutisk aktive indenoindolforbindelserInfo
- Publication number
- NO177932C NO177932C NO915049A NO915049A NO177932C NO 177932 C NO177932 C NO 177932C NO 915049 A NO915049 A NO 915049A NO 915049 A NO915049 A NO 915049A NO 177932 C NO177932 C NO 177932C
- Authority
- NO
- Norway
- Prior art keywords
- lower alkyl
- hydrogen
- group
- cor
- preparation
- Prior art date
Links
- RXXXUIOZOITBII-UHFFFAOYSA-N indeno[1,2-g]indole Chemical class C1=C2C=CC=CC2=C2C1=C1N=CC=C1C=C2 RXXXUIOZOITBII-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000003282 alkyl amino group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO952303A NO300063B1 (no) | 1989-06-22 | 1995-06-12 | Nye indenoindolforbindelser og anvendelse av indenoindolforbindelsene som antioksydanter |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8902274A SE8902274D0 (sv) | 1989-06-22 | 1989-06-22 | Indenoidole compounds ii |
| PCT/GB1990/000949 WO1990015799A1 (en) | 1989-06-22 | 1990-06-20 | Indenoindole compounds ii |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO915049D0 NO915049D0 (no) | 1991-12-20 |
| NO915049L NO915049L (no) | 1992-02-21 |
| NO177932B NO177932B (no) | 1995-09-11 |
| NO177932C true NO177932C (no) | 1995-12-20 |
Family
ID=20376370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO915049A NO177932C (no) | 1989-06-22 | 1991-12-20 | Analogifremgangsmåte ved fremstilling av terapeutisk aktive indenoindolforbindelser |
Country Status (34)
| Country | Link |
|---|---|
| EP (1) | EP0409410B1 (lt) |
| JP (1) | JP3064411B2 (lt) |
| KR (1) | KR920702679A (lt) |
| CN (1) | CN1033029C (lt) |
| AT (1) | ATE135688T1 (lt) |
| BG (1) | BG60317B2 (lt) |
| CA (1) | CA2060897A1 (lt) |
| DD (1) | DD297960A5 (lt) |
| DE (1) | DE69025998T2 (lt) |
| DK (1) | DK0409410T3 (lt) |
| DZ (1) | DZ1428A1 (lt) |
| ES (1) | ES2084660T3 (lt) |
| FI (1) | FI100800B (lt) |
| GR (1) | GR3019779T3 (lt) |
| HR (1) | HRP920903B1 (lt) |
| HU (1) | HUT59097A (lt) |
| IE (1) | IE74682B1 (lt) |
| IL (1) | IL94830A (lt) |
| IS (1) | IS3590A7 (lt) |
| LT (1) | LT3675B (lt) |
| LV (1) | LV10253B (lt) |
| MX (1) | MX21244A (lt) |
| MY (1) | MY107311A (lt) |
| NO (1) | NO177932C (lt) |
| NZ (1) | NZ234175A (lt) |
| PL (1) | PL167761B1 (lt) |
| PT (1) | PT94468B (lt) |
| RO (1) | RO111573B1 (lt) |
| RU (1) | RU2104270C1 (lt) |
| SE (1) | SE8902274D0 (lt) |
| SI (1) | SI9011223B (lt) |
| WO (1) | WO1990015799A1 (lt) |
| YU (1) | YU122390A (lt) |
| ZA (1) | ZA904827B (lt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992006956A1 (en) * | 1990-10-16 | 1992-04-30 | University Of Bath | Indenoindole compounds |
| JPH0656669A (ja) * | 1992-06-11 | 1994-03-01 | Asahi Breweries Ltd | 活性酸素消去作用を持つプテリン誘導体製剤 |
| SE9302431D0 (sv) * | 1993-07-16 | 1993-07-16 | Ab Astra | Use of indenoindole compounds |
| CA2128283A1 (fr) * | 1993-07-20 | 1995-01-21 | Paul Caubere | (thia)cycloalkyl¬b|indoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP2002531569A (ja) * | 1998-12-04 | 2002-09-24 | ワイス | 新規なカリウムチャンネル開放物質としての置換ベンゾフラノインドール及びインデノインドール |
| US6288099B1 (en) | 1998-12-04 | 2001-09-11 | American Home Products Corporation | Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers |
| FR2826009B1 (fr) * | 2001-06-13 | 2003-08-15 | Servier Lab | Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CN101213190A (zh) | 2005-07-14 | 2008-07-02 | Irm责任有限公司 | 用作tpo模拟物的化合物和组合物 |
| DE102006047231B4 (de) * | 2006-10-04 | 2009-02-12 | Hemmerling, Hans-Jörg, Dr. | Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika |
| EA026149B1 (ru) * | 2011-06-16 | 2017-03-31 | Корея Рисерч Инститьют Оф Кемикал Текнолоджи | Производное инданона, его фармацевтически приемлемая соль или оптический изомер, способ его получения и содержащая его фармацевтическая композиция для профилактики или лечения вирусного заболевания |
| LT3882244T (lt) | 2012-12-14 | 2025-05-12 | Korea Research Institute Of Chemical Technology | Junginys, farmaciniu požiūriu priimtina jo druska arba optinis jo izomeras, jo gamybos būdas, farmacinė kompozicija, kurios sudėtyje jis yra kaip veiklioji sudedamoji dalis, skirta virusinių ligų profilaktikai arba gydymui |
| EP4139301A1 (en) | 2020-04-20 | 2023-03-01 | Novartis AG | Antiviral 1,3-di-oxo-indene compounds |
| AU2021260048B2 (en) | 2020-04-20 | 2024-04-18 | Katholieke Universiteit Leuven | Antiviral 1,3-di-oxo-indene compounds |
-
1989
- 1989-06-22 SE SE8902274A patent/SE8902274D0/xx unknown
-
1990
- 1990-06-13 IS IS3590A patent/IS3590A7/is unknown
- 1990-06-20 DE DE69025998T patent/DE69025998T2/de not_active Expired - Fee Related
- 1990-06-20 CA CA002060897A patent/CA2060897A1/en not_active Abandoned
- 1990-06-20 IE IE224790A patent/IE74682B1/en not_active IP Right Cessation
- 1990-06-20 DK DK90306718.9T patent/DK0409410T3/da active
- 1990-06-20 EP EP90306718A patent/EP0409410B1/en not_active Expired - Lifetime
- 1990-06-20 DZ DZ900114A patent/DZ1428A1/fr active
- 1990-06-20 MX MX21244A patent/MX21244A/es unknown
- 1990-06-20 RU SU5010937A patent/RU2104270C1/ru active
- 1990-06-20 RO RO149127A patent/RO111573B1/ro unknown
- 1990-06-20 WO PCT/GB1990/000949 patent/WO1990015799A1/en not_active Ceased
- 1990-06-20 ES ES90306718T patent/ES2084660T3/es not_active Expired - Lifetime
- 1990-06-20 JP JP2508940A patent/JP3064411B2/ja not_active Expired - Fee Related
- 1990-06-20 HU HU904825A patent/HUT59097A/hu unknown
- 1990-06-20 PL PL90285752A patent/PL167761B1/pl unknown
- 1990-06-20 AT AT90306718T patent/ATE135688T1/de active
- 1990-06-21 DD DD90341939A patent/DD297960A5/de not_active IP Right Cessation
- 1990-06-21 MY MYPI90001050A patent/MY107311A/en unknown
- 1990-06-21 IL IL9483090A patent/IL94830A/en not_active IP Right Cessation
- 1990-06-21 ZA ZA904827A patent/ZA904827B/xx unknown
- 1990-06-21 NZ NZ234175A patent/NZ234175A/xx unknown
- 1990-06-22 SI SI9011223A patent/SI9011223B/sl unknown
- 1990-06-22 CN CN90104933A patent/CN1033029C/zh not_active Expired - Fee Related
- 1990-06-22 YU YU122390A patent/YU122390A/sh unknown
- 1990-06-22 PT PT94468A patent/PT94468B/pt not_active IP Right Cessation
-
1991
- 1991-12-19 FI FI915999A patent/FI100800B/fi active
- 1991-12-20 BG BG095667A patent/BG60317B2/bg unknown
- 1991-12-20 NO NO915049A patent/NO177932C/no unknown
- 1991-12-23 KR KR1019910701951A patent/KR920702679A/ko not_active Ceased
-
1992
- 1992-10-02 HR HRP-1223/90A patent/HRP920903B1/xx not_active IP Right Cessation
-
1993
- 1993-06-14 LV LVP-93-568A patent/LV10253B/xx unknown
- 1993-08-30 LT LTIP912A patent/LT3675B/lt not_active IP Right Cessation
-
1996
- 1996-04-29 GR GR960401159T patent/GR3019779T3/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES486349A1 (es) | Procedimiento para la preparacion de 5-(2-imidazolin-2-il)- aminopirimidinas | |
| NO177932C (no) | Analogifremgangsmåte ved fremstilling av terapeutisk aktive indenoindolforbindelser | |
| DE69008142D1 (de) | 4-Substituierten Imidazolen zur Senkung des intraokularen Druckes. | |
| NO161564C (no) | Analogifremgangsmaate ved fremstilling av terapeutisk aktive beta-carbolin-3-oxadiazolylderivater. | |
| AU591640B2 (en) | Quinolonecarboxylic acid derivatives | |
| NO881835L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive bicykliske forbindelser. | |
| SE8902273D0 (sv) | Indenoindole compounds i | |
| EP0285284A3 (en) | N-phenethylaminoalkyl-benzamide anti-arrhythmia agents | |
| GR3003126T3 (en) | Quinolinecarboxylic acid derivatives, a composition comprising the same, process for preparing the same, and the use of the same for the manufacture of medicaments | |
| DE3167347D1 (en) | New benzothiazine derivatives, processes for preparation thereof and use thereof | |
| AU566243B2 (en) | Optically active imidazolylpropanols | |
| DE3782229D1 (de) | Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten. | |
| GB2021587A (en) | Benzoquinolizines | |
| AU2467388A (en) | Quinolinecarboxylic acid derivatives |