GR3019779T3 - Indenoindole compounds - Google Patents

Indenoindole compounds

Info

Publication number
GR3019779T3
GR3019779T3 GR960401159T GR960401159T GR3019779T3 GR 3019779 T3 GR3019779 T3 GR 3019779T3 GR 960401159 T GR960401159 T GR 960401159T GR 960401159 T GR960401159 T GR 960401159T GR 3019779 T3 GR3019779 T3 GR 3019779T3
Authority
GR
Greece
Prior art keywords
lower alkyl
hydrogen
group
cor
alkyl group
Prior art date
Application number
GR960401159T
Other languages
English (en)
Inventor
Malcolm Sainsbury
Howard G Shertzer
Original Assignee
Univ Bath
Univ Cincinnati
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bath, Univ Cincinnati filed Critical Univ Bath
Publication of GR3019779T3 publication Critical patent/GR3019779T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/94[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GR960401159T 1989-06-22 1996-04-29 Indenoindole compounds GR3019779T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902274A SE8902274D0 (sv) 1989-06-22 1989-06-22 Indenoidole compounds ii

Publications (1)

Publication Number Publication Date
GR3019779T3 true GR3019779T3 (en) 1996-07-31

Family

ID=20376370

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401159T GR3019779T3 (en) 1989-06-22 1996-04-29 Indenoindole compounds

Country Status (34)

Country Link
EP (1) EP0409410B1 (el)
JP (1) JP3064411B2 (el)
KR (1) KR920702679A (el)
CN (1) CN1033029C (el)
AT (1) ATE135688T1 (el)
BG (1) BG60317B2 (el)
CA (1) CA2060897A1 (el)
DD (1) DD297960A5 (el)
DE (1) DE69025998T2 (el)
DK (1) DK0409410T3 (el)
DZ (1) DZ1428A1 (el)
ES (1) ES2084660T3 (el)
FI (1) FI100800B (el)
GR (1) GR3019779T3 (el)
HR (1) HRP920903B1 (el)
HU (1) HUT59097A (el)
IE (1) IE74682B1 (el)
IL (1) IL94830A (el)
IS (1) IS3590A7 (el)
LT (1) LT3675B (el)
LV (1) LV10253B (el)
MX (1) MX21244A (el)
MY (1) MY107311A (el)
NO (1) NO177932C (el)
NZ (1) NZ234175A (el)
PL (1) PL167761B1 (el)
PT (1) PT94468B (el)
RO (1) RO111573B1 (el)
RU (1) RU2104270C1 (el)
SE (1) SE8902274D0 (el)
SI (1) SI9011223B (el)
WO (1) WO1990015799A1 (el)
YU (1) YU122390A (el)
ZA (1) ZA904827B (el)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT67274A (en) * 1990-10-16 1995-03-28 Univ Bath Process for producing of tetrahydroindenoindoles and farmaceutical composition comprising them
JPH0656669A (ja) * 1992-06-11 1994-03-01 Asahi Breweries Ltd 活性酸素消去作用を持つプテリン誘導体製剤
SE9302431D0 (sv) * 1993-07-16 1993-07-16 Ab Astra Use of indenoindole compounds
AU675141B2 (en) * 1993-07-20 1997-01-23 Adir Et Compagnie (Thia)cycloalkyl(b)indoles, process for preparing them and pharmaceutical compositions containing them
US6288099B1 (en) 1998-12-04 2001-09-11 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
EP1135393A2 (en) * 1998-12-04 2001-09-26 American Home Products Corporation Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2007009120A2 (en) 2005-07-14 2007-01-18 Irm Llc Heterotetracyclic compounds as tpo mimetics
DE102006047231B4 (de) * 2006-10-04 2009-02-12 Hemmerling, Hans-Jörg, Dr. Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika
MX363405B (es) * 2011-06-16 2019-03-22 Katholieke Univ Leuven K U Leuven R&D Derivados de indanona, sales farmaceuticamente aceptables o isomeros opticos de los mismos, metodo de preparacion de los mismos, y composiciones farmaceuticas que contienen los mismos como ingrediente activo para prevención o tratamiento de enfermedades virales.
EP3882244A1 (en) 2012-12-14 2021-09-22 Korea Research Institute of Chemical Technology Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient
CA3176727A1 (en) 2020-04-20 2021-10-28 Novartis Ag Antiviral 1,3-di-oxo-indene compounds

Also Published As

Publication number Publication date
KR920702679A (ko) 1992-10-06
SE8902274D0 (sv) 1989-06-22
WO1990015799A1 (en) 1990-12-27
DD297960A5 (de) 1992-01-30
IL94830A0 (en) 1991-04-15
PL285752A1 (en) 1991-03-11
LT3675B (en) 1996-01-25
AU644084B2 (en) 1993-12-02
LV10253B (en) 1995-04-20
RO111573B1 (ro) 1996-11-29
SI9011223A (en) 1997-10-31
NO177932C (no) 1995-12-20
NZ234175A (en) 1992-12-23
HU904825D0 (en) 1992-03-30
CA2060897A1 (en) 1990-12-23
ES2084660T3 (es) 1996-05-16
DE69025998D1 (de) 1996-04-25
IE74682B1 (en) 1997-07-30
IS3590A7 (is) 1990-12-23
IE902247A1 (en) 1991-01-16
PT94468B (pt) 1997-12-31
JPH04505923A (ja) 1992-10-15
ATE135688T1 (de) 1996-04-15
EP0409410A1 (en) 1991-01-23
IE902247L (en) 1990-12-22
DE69025998T2 (de) 1996-08-08
MX21244A (es) 1994-03-31
FI100800B (fi) 1998-02-27
AU5836990A (en) 1991-01-08
ZA904827B (en) 1991-04-24
PT94468A (pt) 1991-02-08
IL94830A (en) 1996-07-23
CN1033029C (zh) 1996-10-16
NO177932B (no) 1995-09-11
LV10253A (lv) 1994-10-20
EP0409410B1 (en) 1996-03-20
FI915999A0 (fi) 1991-12-19
LTIP912A (en) 1995-03-27
RU2104270C1 (ru) 1998-02-10
DZ1428A1 (fr) 2004-09-13
PL167761B1 (pl) 1995-10-31
SI9011223B (sl) 1998-08-31
DK0409410T3 (da) 1996-04-29
NO915049D0 (no) 1991-12-20
HRP920903B1 (en) 1998-06-30
YU122390A (sh) 1992-09-07
CN1051554A (zh) 1991-05-22
HUT59097A (en) 1992-04-28
NO915049L (no) 1992-02-21
JP3064411B2 (ja) 2000-07-12
HRP920903A2 (hr) 1994-04-30
MY107311A (en) 1995-11-30
BG60317B2 (bg) 1994-07-25

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