MX21244A - Procedimiento para la preparacion de indenoindoles. - Google Patents
Procedimiento para la preparacion de indenoindoles.Info
- Publication number
- MX21244A MX21244A MX21244A MX2124490A MX21244A MX 21244 A MX21244 A MX 21244A MX 21244 A MX21244 A MX 21244A MX 2124490 A MX2124490 A MX 2124490A MX 21244 A MX21244 A MX 21244A
- Authority
- MX
- Mexico
- Prior art keywords
- lower alkyl
- hydrogen
- group
- cor
- alkyl group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Se proporcionan compuestos de la formula en los que R es hidrógeno o un grupo alquilo inferior o COR15 R1, R2, R11 y R12, son hidrógeno o un grupo alquilo inferior, R3, R4, R5 y R6 son hidrógeno, hidroxi, halógeno un grupo alquilo inferior, un grupo alcoxi inferior o un grupo mono -o di-alquilamono inferior, NH2 o NR13 COR14, R7, R8, R9 y R10 son hidrógeno, hidroxi, un grupo alquilo inferior, un grupo alcoxi inferior, un grupo mono-0 o di-alquilamino inferior, o NH13COR14, en el que R13, R14 y R15 son hidrógeno o un grupo alquilo inferior, enantiómeros y sales de los mismos, con la condición de que cuando R sea COR15, entonces cuando menos uno de R3 a R10 sea hidroxi o un grupo mono- o di-alquilamino inferior, son utiles como antioxidantes, dentro del campo medico y no médico. muchos de los compuestos de fórmula IA y IB son nuevos y se describen varios métodos para prepararlos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8902274A SE8902274D0 (sv) | 1989-06-22 | 1989-06-22 | Indenoidole compounds ii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX21244A true MX21244A (es) | 1994-03-31 |
Family
ID=20376370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX21244A MX21244A (es) | 1989-06-22 | 1990-06-20 | Procedimiento para la preparacion de indenoindoles. |
Country Status (34)
| Country | Link |
|---|---|
| EP (1) | EP0409410B1 (es) |
| JP (1) | JP3064411B2 (es) |
| KR (1) | KR920702679A (es) |
| CN (1) | CN1033029C (es) |
| AT (1) | ATE135688T1 (es) |
| BG (1) | BG60317B2 (es) |
| CA (1) | CA2060897A1 (es) |
| DD (1) | DD297960A5 (es) |
| DE (1) | DE69025998T2 (es) |
| DK (1) | DK0409410T3 (es) |
| DZ (1) | DZ1428A1 (es) |
| ES (1) | ES2084660T3 (es) |
| FI (1) | FI100800B (es) |
| GR (1) | GR3019779T3 (es) |
| HR (1) | HRP920903B1 (es) |
| HU (1) | HUT59097A (es) |
| IE (1) | IE74682B1 (es) |
| IL (1) | IL94830A (es) |
| IS (1) | IS3590A7 (es) |
| LT (1) | LT3675B (es) |
| LV (1) | LV10253B (es) |
| MX (1) | MX21244A (es) |
| MY (1) | MY107311A (es) |
| NO (1) | NO177932C (es) |
| NZ (1) | NZ234175A (es) |
| PL (1) | PL167761B1 (es) |
| PT (1) | PT94468B (es) |
| RO (1) | RO111573B1 (es) |
| RU (1) | RU2104270C1 (es) |
| SE (1) | SE8902274D0 (es) |
| SI (1) | SI9011223B (es) |
| WO (1) | WO1990015799A1 (es) |
| YU (1) | YU122390A (es) |
| ZA (1) | ZA904827B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT67274A (en) * | 1990-10-16 | 1995-03-28 | Univ Bath | Process for producing of tetrahydroindenoindoles and farmaceutical composition comprising them |
| JPH0656669A (ja) * | 1992-06-11 | 1994-03-01 | Asahi Breweries Ltd | 活性酸素消去作用を持つプテリン誘導体製剤 |
| SE9302431D0 (sv) * | 1993-07-16 | 1993-07-16 | Ab Astra | Use of indenoindole compounds |
| AU675141B2 (en) * | 1993-07-20 | 1997-01-23 | Adir Et Compagnie | (Thia)cycloalkyl(b)indoles, process for preparing them and pharmaceutical compositions containing them |
| US6288099B1 (en) | 1998-12-04 | 2001-09-11 | American Home Products Corporation | Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers |
| EP1135393A2 (en) * | 1998-12-04 | 2001-09-26 | American Home Products Corporation | Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers |
| FR2826009B1 (fr) * | 2001-06-13 | 2003-08-15 | Servier Lab | Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| WO2007009120A2 (en) | 2005-07-14 | 2007-01-18 | Irm Llc | Heterotetracyclic compounds as tpo mimetics |
| DE102006047231B4 (de) * | 2006-10-04 | 2009-02-12 | Hemmerling, Hans-Jörg, Dr. | Substituierte Indeno[1,2-b]indolderivate als neue Hemmstoffe der Protein Kinase CK2 und ihre Verwendung als Tumor Therapeutika, Cytostatika und Diagnostika |
| MX363405B (es) * | 2011-06-16 | 2019-03-22 | Katholieke Univ Leuven K U Leuven R&D | Derivados de indanona, sales farmaceuticamente aceptables o isomeros opticos de los mismos, metodo de preparacion de los mismos, y composiciones farmaceuticas que contienen los mismos como ingrediente activo para prevención o tratamiento de enfermedades virales. |
| EP3882244A1 (en) | 2012-12-14 | 2021-09-22 | Korea Research Institute of Chemical Technology | Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient |
| CA3176727A1 (en) | 2020-04-20 | 2021-10-28 | Novartis Ag | Antiviral 1,3-di-oxo-indene compounds |
-
1989
- 1989-06-22 SE SE8902274A patent/SE8902274D0/xx unknown
-
1990
- 1990-06-13 IS IS3590A patent/IS3590A7/is unknown
- 1990-06-20 PL PL90285752A patent/PL167761B1/pl unknown
- 1990-06-20 DE DE69025998T patent/DE69025998T2/de not_active Expired - Fee Related
- 1990-06-20 CA CA002060897A patent/CA2060897A1/en not_active Abandoned
- 1990-06-20 IE IE224790A patent/IE74682B1/en not_active IP Right Cessation
- 1990-06-20 WO PCT/GB1990/000949 patent/WO1990015799A1/en active IP Right Grant
- 1990-06-20 MX MX21244A patent/MX21244A/es unknown
- 1990-06-20 HU HU904825A patent/HUT59097A/hu unknown
- 1990-06-20 DK DK90306718.9T patent/DK0409410T3/da active
- 1990-06-20 DZ DZ900114A patent/DZ1428A1/fr active
- 1990-06-20 RU SU5010937A patent/RU2104270C1/ru active
- 1990-06-20 RO RO149127A patent/RO111573B1/ro unknown
- 1990-06-20 JP JP2508940A patent/JP3064411B2/ja not_active Expired - Fee Related
- 1990-06-20 AT AT90306718T patent/ATE135688T1/de active
- 1990-06-20 ES ES90306718T patent/ES2084660T3/es not_active Expired - Lifetime
- 1990-06-20 EP EP90306718A patent/EP0409410B1/en not_active Expired - Lifetime
- 1990-06-21 MY MYPI90001050A patent/MY107311A/en unknown
- 1990-06-21 DD DD90341939A patent/DD297960A5/de not_active IP Right Cessation
- 1990-06-21 ZA ZA904827A patent/ZA904827B/xx unknown
- 1990-06-21 IL IL9483090A patent/IL94830A/en not_active IP Right Cessation
- 1990-06-21 NZ NZ234175A patent/NZ234175A/xx unknown
- 1990-06-22 PT PT94468A patent/PT94468B/pt not_active IP Right Cessation
- 1990-06-22 SI SI9011223A patent/SI9011223B/sl unknown
- 1990-06-22 CN CN90104933A patent/CN1033029C/zh not_active Expired - Fee Related
- 1990-06-22 YU YU122390A patent/YU122390A/sh unknown
-
1991
- 1991-12-19 FI FI915999A patent/FI100800B/fi active
- 1991-12-20 NO NO915049A patent/NO177932C/no unknown
- 1991-12-20 BG BG095667A patent/BG60317B2/bg unknown
- 1991-12-23 KR KR1019910701951A patent/KR920702679A/ko not_active Application Discontinuation
-
1992
- 1992-10-02 HR HRP-1223/90A patent/HRP920903B1/xx not_active IP Right Cessation
-
1993
- 1993-06-14 LV LVP-93-568A patent/LV10253B/xx unknown
- 1993-08-30 LT LTIP912A patent/LT3675B/lt not_active IP Right Cessation
-
1996
- 1996-04-29 GR GR960401159T patent/GR3019779T3/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2056962T3 (es) | Un procedimiento para la preparacion de nuevos derivados de camptotecina. | |
| ES2070660B1 (es) | Un procedimiento para la preparacion de 2,5-damino-3-hidroxihexanos sustituidos, utiles como inhibidores de proteasas retrovirales. | |
| DE3473763D1 (en) | Novel 4'-demethyl-4-epipodophyllotoxin derivatives, a process for their preparation and their use as medicaments | |
| MX21244A (es) | Procedimiento para la preparacion de indenoindoles. | |
| ES2006142A6 (es) | Un metodo para preparar derivados de acidos quinolincarboxilicos | |
| SE8902273D0 (sv) | Indenoindole compounds i | |
| ES528816A0 (es) | Procedimiento de producir compuestos para el tratamiento de la hipertension | |
| ES557647A0 (es) | Procedimiento para preparar nuevos derivados de 3-piridil-metilnaftilo | |
| JO1676B1 (en) | Extra compounds indinol II | |
| ES524375A0 (es) | Un procedimiento para preparar un compuesto de nitrato piridilalquilico | |
| ES504259A0 (es) | Procedimiento para la obtencion de nuevos derivados de la tiazolo (3,2-a) pirimidina | |
| ES519627A0 (es) | Procedimiento para la preparacion de derivados de carbaciclina. | |
| AU566243B2 (en) | Optically active imidazolylpropanols | |
| ES2063046T3 (es) | Procedimiento para la preparacion y utilizacion de 4-oxo-4-((r)-fenil)-butenoil-salicilatos y composiciones farmaceuticas que los contienen. | |
| DE68909961D1 (de) | 2-Aminoacetamid Derivate. | |
| ES2045335T3 (es) | Un procedimiento para la preparacion de nuevas s-difluorometilhomocisteinas. |