NO172287C - Fremgangsmaate for fremstilling av 2-(2-(4-((4-klorfenyl)-fenylmethyl)-1-piperazinyl)-ethoxy)-eddiksyre og dens dihydroklorid - Google Patents

Fremgangsmaate for fremstilling av 2-(2-(4-((4-klorfenyl)-fenylmethyl)-1-piperazinyl)-ethoxy)-eddiksyre og dens dihydroklorid

Info

Publication number
NO172287C
NO172287C NO894650A NO894650A NO172287C NO 172287 C NO172287 C NO 172287C NO 894650 A NO894650 A NO 894650A NO 894650 A NO894650 A NO 894650A NO 172287 C NO172287 C NO 172287C
Authority
NO
Norway
Prior art keywords
chlorphenyl
phenylmethyl
dihydrochloride
piperazinyl
ethoxy
Prior art date
Application number
NO894650A
Other languages
English (en)
Other versions
NO894650L (no
NO894650D0 (no
NO172287B (no
Inventor
Guy Bodson
Eric Cossement
Jean Gobert
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of NO894650D0 publication Critical patent/NO894650D0/no
Publication of NO894650L publication Critical patent/NO894650L/no
Publication of NO172287B publication Critical patent/NO172287B/no
Publication of NO172287C publication Critical patent/NO172287C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO894650A 1988-11-23 1989-11-22 Fremgangsmaate for fremstilling av 2-(2-(4-((4-klorfenyl)-fenylmethyl)-1-piperazinyl)-ethoxy)-eddiksyre og dens dihydroklorid NO172287C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888827390A GB8827390D0 (en) 1988-11-23 1988-11-23 Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride

Publications (4)

Publication Number Publication Date
NO894650D0 NO894650D0 (no) 1989-11-22
NO894650L NO894650L (no) 1990-05-25
NO172287B NO172287B (no) 1993-03-22
NO172287C true NO172287C (no) 1993-06-30

Family

ID=10647346

Family Applications (1)

Application Number Title Priority Date Filing Date
NO894650A NO172287C (no) 1988-11-23 1989-11-22 Fremgangsmaate for fremstilling av 2-(2-(4-((4-klorfenyl)-fenylmethyl)-1-piperazinyl)-ethoxy)-eddiksyre og dens dihydroklorid

Country Status (17)

Country Link
KR (1) KR970009727B1 (no)
AT (1) AT398970B (no)
CA (1) CA1320732C (no)
CY (1) CY1696A (no)
DK (1) DK174289B1 (no)
ES (1) ES2018967A6 (no)
FI (1) FI91861C (no)
GB (2) GB8827390D0 (no)
GR (1) GR1000576B (no)
HK (1) HK45493A (no)
HU (1) HU208002B (no)
NO (1) NO172287C (no)
PH (1) PH26334A (no)
PL (1) PL161374B1 (no)
PT (1) PT92363B (no)
RU (1) RU1838306C (no)
SG (1) SG12793G (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10199031I2 (de) * 1992-09-24 2004-09-23 Sepracor Inc Verwendung von (-) Cetrizin zur Behandlung allergischer Rhinitis und Asthma.
ATE177636T1 (de) * 1992-09-24 1999-04-15 Sepracor Inc Transdermale behandlung der nesselsucht mit optisch reinem (+)-cetirizin
BE1010095A3 (fr) * 1996-04-10 1997-12-02 Ucb Sa Procede de preparation de l'acide 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl] ethoxy]-acetique et de ses sels.
BE1010094A3 (fr) * 1996-04-10 1997-12-02 Ucb Sa Nouveaux [2-(1-piperazinyl)ethoxy] methyle substitues.
CA2180993A1 (en) * 1996-07-11 1998-01-12 Yong Tao Methods for the manufacture of cetirizine
EP0919550A1 (en) * 1997-11-26 1999-06-02 Ucb, S.A. Pseudopolymorphic forms of 2-2-4-bis(4-fluorophenyl)methyl-1-piperazinyl-ethoxy acetic acid dihydrochloride
IL124195A (en) * 1998-04-23 2000-08-31 Chemagis Ltd Process for the preparation of esters of 2-¬4-¬4-chlorophenyl¾phenylmethyl¾-1-piperazinyl¬ethoxy¾acetic acid
DK176706B1 (da) * 1999-03-04 2009-03-30 Sandoz As Fremgangsmåde til fremstilling af 2-{2-[4-(diphenylmethyl)-1-piperazinyl]ethoxy}-eddikesyre-forbindelser eller salte deraf
US6265579B1 (en) * 1999-10-29 2001-07-24 Salsbury Chemicals, Inc. Process for preparing piperazine-substituted aliphatic carboxylates
US7199241B1 (en) 2001-05-29 2007-04-03 Ucb, S.A. Process for preparing (S) and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
US6977301B1 (en) 2001-05-29 2005-12-20 Ucb, S.A. Process for preparing (S) and (R)—2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
AU2003238883A1 (en) * 2002-06-05 2003-12-22 Dr.Reddy's Laboratories Ltd. A novel amorphous form of (2-(4-((4-chlorophenyl)-phenyl methyl)-1- piperazinyl) ethoxy) acetic acid dihydrochloride (cetirizine dihydrochloride)
CN100378086C (zh) 2003-01-23 2008-04-02 Ucb法奇姆股份有限公司 哌嗪衍生物和它们作为合成中间体的应用
US20060258684A1 (en) * 2003-05-21 2006-11-16 Singh Prasad S 2-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl]ethoxy]acetic acid monohydrochloride as anti-allergenic compound and process for its production
US20110172425A1 (en) 2008-09-17 2011-07-14 Calyx Chemicals And Pharmaceuticals Pvt. Ltd. Novel water based process for the preparation of substituted diphenylmethyl piperazines
KR101418404B1 (ko) 2012-01-06 2014-07-10 한미약품 주식회사 레보세티리진 또는 이의 약학적으로 허용가능한 염 및 몬테루카스트 또는 이의 약학적으로 허용가능한 염을 함유하는 안정한 경구투여용 약학 제제
KR102226833B1 (ko) 2013-06-28 2021-03-12 한미약품 주식회사 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB817231A (en) * 1956-01-27 1959-07-29 Henri Morren New derivatives of n-mono-benzhydryl-piperazine and process for the preparation thereof
US3090725A (en) * 1960-02-29 1963-05-21 Burroughs Wellcome Co Phosphorylated quaternary ammonium compounds of improved oral absorption
NO155805C (no) * 1981-02-06 1987-06-10 Ucb Sa Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter.

Also Published As

Publication number Publication date
FI91861C (fi) 1994-08-25
PH26334A (en) 1992-04-29
PL161374B1 (pl) 1993-06-30
DK586589A (da) 1990-05-24
CY1696A (en) 1994-01-14
HK45493A (en) 1993-05-21
NO894650L (no) 1990-05-25
GR890100771A (en) 1990-12-31
NO894650D0 (no) 1989-11-22
PT92363B (pt) 1995-07-18
AT398970B (de) 1995-02-27
DK586589D0 (da) 1989-11-22
HU896130D0 (en) 1990-02-28
SG12793G (en) 1993-04-16
NO172287B (no) 1993-03-22
CA1320732C (en) 1993-07-27
RU1838306C (ru) 1993-08-30
FI91861B (fi) 1994-05-13
HU208002B (en) 1993-07-28
HUT53626A (en) 1990-11-28
FI895563A0 (fi) 1989-11-22
GB2225320A (en) 1990-05-30
GB8926242D0 (en) 1990-01-10
ES2018967A6 (es) 1991-05-16
KR900007824A (ko) 1990-06-02
ATA266489A (de) 1994-07-15
PT92363A (pt) 1990-05-31
DK174289B1 (da) 2002-11-18
GB8827390D0 (en) 1988-12-29
KR970009727B1 (ko) 1997-06-17
GR1000576B (el) 1992-08-26
GB2225320B (en) 1992-09-02

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