CY1696A - Process for the preparation of 2-(2-(-4((4-chlorophenyl)phenylmethyl)- 1-piperazinyl)ethoxy)-acetic acid and its dihydrochloride - Google Patents

Process for the preparation of 2-(2-(-4((4-chlorophenyl)phenylmethyl)- 1-piperazinyl)ethoxy)-acetic acid and its dihydrochloride

Info

Publication number
CY1696A
CY1696A CY160694A CY160694A CY1696A CY 1696 A CY1696 A CY 1696A CY 160694 A CY160694 A CY 160694A CY 160694 A CY160694 A CY 160694A CY 1696 A CY1696 A CY 1696A
Authority
CY
Cyprus
Prior art keywords
phenylmethyl
dihydrochloride
piperazinyl
chlorophenyl
ethoxy
Prior art date
Application number
CY160694A
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of CY1696A publication Critical patent/CY1696A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CY160694A 1988-11-23 1994-01-14 Process for the preparation of 2-(2-(-4((4-chlorophenyl)phenylmethyl)- 1-piperazinyl)ethoxy)-acetic acid and its dihydrochloride CY1696A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888827390A GB8827390D0 (en) 1988-11-23 1988-11-23 Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride

Publications (1)

Publication Number Publication Date
CY1696A true CY1696A (en) 1994-01-14

Family

ID=10647346

Family Applications (1)

Application Number Title Priority Date Filing Date
CY160694A CY1696A (en) 1988-11-23 1994-01-14 Process for the preparation of 2-(2-(-4((4-chlorophenyl)phenylmethyl)- 1-piperazinyl)ethoxy)-acetic acid and its dihydrochloride

Country Status (17)

Country Link
KR (1) KR970009727B1 (en)
AT (1) AT398970B (en)
CA (1) CA1320732C (en)
CY (1) CY1696A (en)
DK (1) DK174289B1 (en)
ES (1) ES2018967A6 (en)
FI (1) FI91861C (en)
GB (2) GB8827390D0 (en)
GR (1) GR1000576B (en)
HK (1) HK45493A (en)
HU (1) HU208002B (en)
NO (1) NO172287C (en)
PH (1) PH26334A (en)
PL (1) PL161374B1 (en)
PT (1) PT92363B (en)
RU (1) RU1838306C (en)
SG (1) SG12793G (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0885611A3 (en) * 1992-09-24 1999-01-07 Sepracor, Inc. Methods and compositions for treating allergic disorders using optically pure (+) cetirizine
EP0950412A3 (en) * 1992-09-24 2001-05-16 Sepracor, Inc. Compositions for treating allergic disorders using (-) cetirizine
BE1010095A3 (en) * 1996-04-10 1997-12-02 Ucb Sa METHOD OF PREPARATION OF ACID 2- [2- [4 - [(4-Chlorophenyl) phenylmethyl] -1-PIPERAZINYL] ETHOXY] acetic acid AND ITS SALTS.
BE1010094A3 (en) * 1996-04-10 1997-12-02 Ucb Sa NEW [2- (1-piperazinyl) ethoxy] SUBSTITUTED.
CA2180993A1 (en) * 1996-07-11 1998-01-12 Yong Tao Methods for the manufacture of cetirizine
EP0919550A1 (en) * 1997-11-26 1999-06-02 Ucb, S.A. Pseudopolymorphic forms of 2-2-4-bis(4-fluorophenyl)methyl-1-piperazinyl-ethoxy acetic acid dihydrochloride
IL124195A (en) * 1998-04-23 2000-08-31 Chemagis Ltd Process for the preparation of esters of 2-¬4-¬4-chlorophenyl¾phenylmethyl¾-1-piperazinyl¬ethoxy¾acetic acid
DK176706B1 (en) * 1999-03-04 2009-03-30 Sandoz As Process for the preparation of 2- {2- [4- (diphenylmethyl) -1-piperazinyl] ethoxy} -acetic acid compounds or salts thereof
US6265579B1 (en) * 1999-10-29 2001-07-24 Salsbury Chemicals, Inc. Process for preparing piperazine-substituted aliphatic carboxylates
US6977301B1 (en) 2001-05-29 2005-12-20 Ucb, S.A. Process for preparing (S) and (R)—2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
US7199241B1 (en) 2001-05-29 2007-04-03 Ucb, S.A. Process for preparing (S) and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
AU2003237394A1 (en) * 2002-06-05 2003-12-22 Dr. Reddy's Laboratories Limited Crystalline (2-(4-((4-chlorophenyl)-phenyl methyl)-1-piperazinyl) ethoxy) acetic acid dihydrochloride
AU2004205494B2 (en) 2003-01-23 2009-04-30 Ucb Farchim Sa Piperazine derivatives and their use as synthesis intermediates
AU2003228011A1 (en) * 2003-05-21 2004-12-13 Wockhardt Limited 2-(2-(4-((4-chlorophenyl) phenylmethyl)-1-piperazinyl)ethoxy)acetic acid monohydrochloride as anti-allergenic compound and process for its production
WO2010046908A2 (en) 2008-09-17 2010-04-29 Calyx Chemicals And Pharmaceuticals Pvt. Ltd. Novel water based process for the preparation of substituted diphenylmethyl piperazines
KR101418404B1 (en) 2012-01-06 2014-07-10 한미약품 주식회사 Stable pharmaceutical formulation for oral administration comprising levocetirizine or a pharmaceutically acceptable salt thereof, and montelukast or a pharmaceutically acceptable salt thereof
KR102226833B1 (en) 2013-06-28 2021-03-12 한미약품 주식회사 Complex granule formulation having improved stability comprising levocetirizine and montelukast

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB817231A (en) * 1956-01-27 1959-07-29 Henri Morren New derivatives of n-mono-benzhydryl-piperazine and process for the preparation thereof
US3090725A (en) * 1960-02-29 1963-05-21 Burroughs Wellcome Co Phosphorylated quaternary ammonium compounds of improved oral absorption
FI75816C (en) * 1981-02-06 1988-08-08 Ucb Sa Process for the preparation of therapeutically active 2- [4- (diphenylmethyl) -1-piperazinyl] -acetic acid or its amide

Also Published As

Publication number Publication date
FI895563A0 (en) 1989-11-22
GB2225320B (en) 1992-09-02
GR890100771A (en) 1990-12-31
KR970009727B1 (en) 1997-06-17
PT92363B (en) 1995-07-18
RU1838306C (en) 1993-08-30
ES2018967A6 (en) 1991-05-16
HU896130D0 (en) 1990-02-28
AT398970B (en) 1995-02-27
DK586589D0 (en) 1989-11-22
PH26334A (en) 1992-04-29
GB8926242D0 (en) 1990-01-10
NO172287B (en) 1993-03-22
FI91861C (en) 1994-08-25
KR900007824A (en) 1990-06-02
FI91861B (en) 1994-05-13
HUT53626A (en) 1990-11-28
HK45493A (en) 1993-05-21
CA1320732C (en) 1993-07-27
GB2225320A (en) 1990-05-30
PL161374B1 (en) 1993-06-30
GR1000576B (en) 1992-08-26
DK586589A (en) 1990-05-24
PT92363A (en) 1990-05-31
NO172287C (en) 1993-06-30
HU208002B (en) 1993-07-28
NO894650D0 (en) 1989-11-22
ATA266489A (en) 1994-07-15
NO894650L (en) 1990-05-25
SG12793G (en) 1993-04-16
GB8827390D0 (en) 1988-12-29
DK174289B1 (en) 2002-11-18

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