DK586589A - METHOD FOR PREPARING 2- (2- (4 - (((4-CHLORPHENYL) PHENYLMETHYL) -1-PIPERAZINYL) ETHOXY) ACETIC ACID AND ITS DIHYDROCHLORIDE - Google Patents
METHOD FOR PREPARING 2- (2- (4 - (((4-CHLORPHENYL) PHENYLMETHYL) -1-PIPERAZINYL) ETHOXY) ACETIC ACID AND ITS DIHYDROCHLORIDEInfo
- Publication number
- DK586589A DK586589A DK586589A DK586589A DK586589A DK 586589 A DK586589 A DK 586589A DK 586589 A DK586589 A DK 586589A DK 586589 A DK586589 A DK 586589A DK 586589 A DK586589 A DK 586589A
- Authority
- DK
- Denmark
- Prior art keywords
- chlorphenyl
- phenylmethyl
- dihydrochloride
- piperazinyl
- ethoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8827390 | 1988-11-23 | ||
GB888827390A GB8827390D0 (en) | 1988-11-23 | 1988-11-23 | Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride |
Publications (3)
Publication Number | Publication Date |
---|---|
DK586589D0 DK586589D0 (en) | 1989-11-22 |
DK586589A true DK586589A (en) | 1990-05-24 |
DK174289B1 DK174289B1 (en) | 2002-11-18 |
Family
ID=10647346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198905865A DK174289B1 (en) | 1988-11-23 | 1989-11-22 | Process for the preparation of 2- [2- [4 - [(4-chlorophenyl) phenylmethyl] -1-piperazinyl] ethoxy] acetic acid and its dihydrochloride |
Country Status (17)
Country | Link |
---|---|
KR (1) | KR970009727B1 (en) |
AT (1) | AT398970B (en) |
CA (1) | CA1320732C (en) |
CY (1) | CY1696A (en) |
DK (1) | DK174289B1 (en) |
ES (1) | ES2018967A6 (en) |
FI (1) | FI91861C (en) |
GB (2) | GB8827390D0 (en) |
GR (1) | GR1000576B (en) |
HK (1) | HK45493A (en) |
HU (1) | HU208002B (en) |
NO (1) | NO172287C (en) |
PH (1) | PH26334A (en) |
PL (1) | PL161374B1 (en) |
PT (1) | PT92363B (en) |
RU (1) | RU1838306C (en) |
SG (1) | SG12793G (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08501561A (en) * | 1992-09-24 | 1996-02-20 | セプラコア,インコーポレイテッド | (-) Composition for treating allergic diseases using cetirizine |
DK0661975T3 (en) * | 1992-09-24 | 1999-09-27 | Sepracor Inc | Transdermal treatment of hives using optically pure (+) - cetirizine |
BE1010094A3 (en) | 1996-04-10 | 1997-12-02 | Ucb Sa | NEW [2- (1-piperazinyl) ethoxy] SUBSTITUTED. |
BE1010095A3 (en) * | 1996-04-10 | 1997-12-02 | Ucb Sa | METHOD OF PREPARATION OF ACID 2- [2- [4 - [(4-Chlorophenyl) phenylmethyl] -1-PIPERAZINYL] ETHOXY] acetic acid AND ITS SALTS. |
CA2180993A1 (en) * | 1996-07-11 | 1998-01-12 | Yong Tao | Methods for the manufacture of cetirizine |
EP0919550A1 (en) * | 1997-11-26 | 1999-06-02 | Ucb, S.A. | Pseudopolymorphic forms of 2-2-4-bis(4-fluorophenyl)methyl-1-piperazinyl-ethoxy acetic acid dihydrochloride |
IL124195A (en) * | 1998-04-23 | 2000-08-31 | Chemagis Ltd | Process for the preparation of esters of 2-¬4-¬4-chlorophenyl¾phenylmethyl¾-1-piperazinyl¬ethoxy¾acetic acid |
DK176706B1 (en) * | 1999-03-04 | 2009-03-30 | Sandoz As | Process for the preparation of 2- {2- [4- (diphenylmethyl) -1-piperazinyl] ethoxy} -acetic acid compounds or salts thereof |
US6265579B1 (en) * | 1999-10-29 | 2001-07-24 | Salsbury Chemicals, Inc. | Process for preparing piperazine-substituted aliphatic carboxylates |
US6977301B1 (en) | 2001-05-29 | 2005-12-20 | Ucb, S.A. | Process for preparing (S) and (R)—2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide |
US7199241B1 (en) | 2001-05-29 | 2007-04-03 | Ucb, S.A. | Process for preparing (S) and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide |
AU2003238883A1 (en) * | 2002-06-05 | 2003-12-22 | Dr.Reddy's Laboratories Ltd. | A novel amorphous form of (2-(4-((4-chlorophenyl)-phenyl methyl)-1- piperazinyl) ethoxy) acetic acid dihydrochloride (cetirizine dihydrochloride) |
WO2004065360A2 (en) * | 2003-01-23 | 2004-08-05 | Ucb Farchim Sa | Piperazine derivatives and their use as synthesis intermediates |
AU2003228011A1 (en) * | 2003-05-21 | 2004-12-13 | Wockhardt Limited | 2-(2-(4-((4-chlorophenyl) phenylmethyl)-1-piperazinyl)ethoxy)acetic acid monohydrochloride as anti-allergenic compound and process for its production |
US20110172425A1 (en) | 2008-09-17 | 2011-07-14 | Calyx Chemicals And Pharmaceuticals Pvt. Ltd. | Novel water based process for the preparation of substituted diphenylmethyl piperazines |
KR101418404B1 (en) | 2012-01-06 | 2014-07-10 | 한미약품 주식회사 | Stable pharmaceutical formulation for oral administration comprising levocetirizine or a pharmaceutically acceptable salt thereof, and montelukast or a pharmaceutically acceptable salt thereof |
KR102226833B1 (en) | 2013-06-28 | 2021-03-12 | 한미약품 주식회사 | Complex granule formulation having improved stability comprising levocetirizine and montelukast |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB817231A (en) * | 1956-01-27 | 1959-07-29 | Henri Morren | New derivatives of n-mono-benzhydryl-piperazine and process for the preparation thereof |
US3090725A (en) * | 1960-02-29 | 1963-05-21 | Burroughs Wellcome Co | Phosphorylated quaternary ammonium compounds of improved oral absorption |
NO155805C (en) * | 1981-02-06 | 1987-06-10 | Ucb Sa | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 2- (4- (DIPHENYLMETHYL) -1-PIPERAZINYL) -ACDIC ACIDS AND THEIR AMIDS AND NON-TOXIC SALTS. |
-
1988
- 1988-11-23 GB GB888827390A patent/GB8827390D0/en active Pending
-
1989
- 1989-09-29 CA CA000614708A patent/CA1320732C/en not_active Expired - Fee Related
- 1989-11-20 GR GR890100771A patent/GR1000576B/en not_active IP Right Cessation
- 1989-11-21 GB GB8926242A patent/GB2225320B/en not_active Expired - Lifetime
- 1989-11-21 PT PT92363A patent/PT92363B/en not_active IP Right Cessation
- 1989-11-22 NO NO894650A patent/NO172287C/en not_active IP Right Cessation
- 1989-11-22 RU SU894742406A patent/RU1838306C/en active
- 1989-11-22 ES ES8903974A patent/ES2018967A6/en not_active Expired - Lifetime
- 1989-11-22 DK DK198905865A patent/DK174289B1/en not_active IP Right Cessation
- 1989-11-22 AT AT0266489A patent/AT398970B/en not_active IP Right Cessation
- 1989-11-22 FI FI895563A patent/FI91861C/en not_active IP Right Cessation
- 1989-11-22 PL PL1989282411A patent/PL161374B1/en unknown
- 1989-11-22 HU HU896130A patent/HU208002B/en not_active IP Right Cessation
- 1989-11-23 KR KR1019890017039A patent/KR970009727B1/en not_active IP Right Cessation
- 1989-11-23 PH PH39569A patent/PH26334A/en unknown
-
1993
- 1993-02-06 SG SG127/93A patent/SG12793G/en unknown
- 1993-05-13 HK HK454/93A patent/HK45493A/en not_active IP Right Cessation
-
1994
- 1994-01-14 CY CY160694A patent/CY1696A/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB2225320B (en) | 1992-09-02 |
GB8926242D0 (en) | 1990-01-10 |
FI91861C (en) | 1994-08-25 |
GB2225320A (en) | 1990-05-30 |
KR970009727B1 (en) | 1997-06-17 |
NO894650L (en) | 1990-05-25 |
PT92363A (en) | 1990-05-31 |
PH26334A (en) | 1992-04-29 |
HUT53626A (en) | 1990-11-28 |
DK174289B1 (en) | 2002-11-18 |
NO172287C (en) | 1993-06-30 |
DK586589D0 (en) | 1989-11-22 |
KR900007824A (en) | 1990-06-02 |
ES2018967A6 (en) | 1991-05-16 |
GB8827390D0 (en) | 1988-12-29 |
SG12793G (en) | 1993-04-16 |
FI91861B (en) | 1994-05-13 |
CY1696A (en) | 1994-01-14 |
GR890100771A (en) | 1990-12-31 |
NO894650D0 (en) | 1989-11-22 |
PT92363B (en) | 1995-07-18 |
CA1320732C (en) | 1993-07-27 |
HU208002B (en) | 1993-07-28 |
ATA266489A (en) | 1994-07-15 |
GR1000576B (en) | 1992-08-26 |
AT398970B (en) | 1995-02-27 |
FI895563A0 (en) | 1989-11-22 |
PL161374B1 (en) | 1993-06-30 |
HK45493A (en) | 1993-05-21 |
HU896130D0 (en) | 1990-02-28 |
RU1838306C (en) | 1993-08-30 |
NO172287B (en) | 1993-03-22 |
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