NO166314C - Fremgangsmaate for fremstilling av en plasminogenaktivatoravledet fra human nyre. - Google Patents

Fremgangsmaate for fremstilling av en plasminogenaktivatoravledet fra human nyre.

Info

Publication number
NO166314C
NO166314C NO84842468A NO842468A NO166314C NO 166314 C NO166314 C NO 166314C NO 84842468 A NO84842468 A NO 84842468A NO 842468 A NO842468 A NO 842468A NO 166314 C NO166314 C NO 166314C
Authority
NO
Norway
Prior art keywords
procedure
divided
manufacturing
plasminogen activator
human kidney
Prior art date
Application number
NO84842468A
Other languages
English (en)
Norwegian (no)
Other versions
NO842468L (no
NO166314B (no
Inventor
Seishi Takahashi
Kazushi Morimoto
Yoshikazu Fujisawa
Fumiaki Ikeda
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP57189067A external-priority patent/JPS5980613A/ja
Priority claimed from JP57189065A external-priority patent/JPH0637398B2/ja
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of NO842468L publication Critical patent/NO842468L/no
Publication of NO166314B publication Critical patent/NO166314B/no
Publication of NO166314C publication Critical patent/NO166314C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO84842468A 1982-10-29 1984-06-19 Fremgangsmaate for fremstilling av en plasminogenaktivatoravledet fra human nyre. NO166314C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP57189067A JPS5980613A (ja) 1982-10-29 1982-10-29 新規なプラスミノ−ゲン・アクチベ−タ及びその製造方法
JP57189065A JPH0637398B2 (ja) 1982-10-29 1982-10-29 血栓溶解剤
PCT/JP1983/000386 WO1984001714A1 (en) 1982-10-29 1983-10-27 Novel plasminogen activator, process for its preparation, and thrombolytic drug containing the same

Publications (3)

Publication Number Publication Date
NO842468L NO842468L (no) 1984-06-19
NO166314B NO166314B (no) 1991-03-25
NO166314C true NO166314C (no) 1991-07-03

Family

ID=26505289

Family Applications (1)

Application Number Title Priority Date Filing Date
NO84842468A NO166314C (no) 1982-10-29 1984-06-19 Fremgangsmaate for fremstilling av en plasminogenaktivatoravledet fra human nyre.

Country Status (12)

Country Link
EP (1) EP0124613B1 (de)
CA (1) CA1221029A (de)
CH (1) CH660742A5 (de)
DE (1) DE3390272C2 (de)
DK (1) DK169686B1 (de)
FI (1) FI80597C (de)
GB (1) GB2138824B (de)
IT (1) IT1169910B (de)
NL (1) NL191755C (de)
NO (1) NO166314C (de)
SE (1) SE8403375L (de)
WO (1) WO1984001714A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151996B1 (de) * 1984-01-30 1991-04-03 Asahi Kasei Kogyo Kabushiki Kaisha Verfahren zur Herstellung eines doppelkettigen Plasminogenaktivators
US4929444A (en) * 1985-05-28 1990-05-29 Burroughs Wellcome Co. Low pH pharmaceutical formulation containing t-PA
BE904831A (fr) * 1985-05-28 1986-11-27 Wellcome Found Composition d'activateur tissulaire du plasminogene.
AU7709287A (en) * 1986-07-16 1988-02-10 Celltech Limited Process for purifying a plasminogen activator
JPS6379591A (ja) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc tPAの精製方法
AU1668988A (en) * 1987-06-03 1988-12-08 Smithkline Beckman Corporation Purification of tpa
DE3726019A1 (de) * 1987-08-05 1989-02-16 Boehringer Mannheim Gmbh Verfahren zur abtrennung und reinigung von t-pa

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
JPS5913732A (ja) * 1982-07-16 1984-01-24 Mitsui Toatsu Chem Inc 血栓溶解剤
IE81073B1 (en) * 1986-03-18 2000-01-12 Genentech Inc Modified human tissue-type plasminogen activator and its preparation

Also Published As

Publication number Publication date
GB8414992D0 (en) 1984-07-18
GB2138824A (en) 1984-10-31
DK307384D0 (da) 1984-06-22
CA1221029A (en) 1987-04-28
EP0124613B1 (de) 1992-12-30
IT1169910B (it) 1987-06-03
SE8403375D0 (sv) 1984-06-25
SE8403375L (sv) 1984-06-25
DK169686B1 (da) 1995-01-09
DE3390272C2 (de) 1987-09-17
NL191755C (nl) 1996-07-02
NO842468L (no) 1984-06-19
FI842627A (fi) 1984-06-29
EP0124613A1 (de) 1984-11-14
FI80597B (fi) 1990-03-30
NL8320346A (nl) 1984-09-03
IT8323533A0 (it) 1983-10-28
CH660742A5 (de) 1987-06-15
FI842627A0 (fi) 1984-06-29
NO166314B (no) 1991-03-25
DK307384A (da) 1984-06-22
WO1984001714A1 (en) 1984-05-10
NL191755B (nl) 1996-03-01
GB2138824B (en) 1986-12-31
EP0124613A4 (de) 1986-07-29
DE3390272T1 (de) 1984-11-29
FI80597C (fi) 1990-07-10

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