NO163814C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-substituerte 4-hydroksymetyl-pyrrolidinon-derivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-substituerte 4-hydroksymetyl-pyrrolidinon-derivater.

Info

Publication number
NO163814C
NO163814C NO843004A NO843004A NO163814C NO 163814 C NO163814 C NO 163814C NO 843004 A NO843004 A NO 843004A NO 843004 A NO843004 A NO 843004A NO 163814 C NO163814 C NO 163814C
Authority
NO
Norway
Prior art keywords
substituted
pyrrolidinon
hydroxymethyl
derivatives
preparation
Prior art date
Application number
NO843004A
Other languages
English (en)
Norwegian (no)
Other versions
NO843004L (no
NO163814B (no
Inventor
Karl-Heinz Weber
Gerhard Walther
Claus Schneider
Dieter Hinzen
Franz Josef Kuhn
Erich Lehr
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO843004L publication Critical patent/NO843004L/no
Publication of NO163814B publication Critical patent/NO163814B/no
Publication of NO163814C publication Critical patent/NO163814C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Catalysts (AREA)
NO843004A 1983-07-25 1984-07-24 Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-substituerte 4-hydroksymetyl-pyrrolidinon-derivater. NO163814C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833326724 DE3326724A1 (de) 1983-07-25 1983-07-25 In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte

Publications (3)

Publication Number Publication Date
NO843004L NO843004L (no) 1985-01-28
NO163814B NO163814B (no) 1990-04-17
NO163814C true NO163814C (no) 1990-07-25

Family

ID=6204831

Family Applications (1)

Application Number Title Priority Date Filing Date
NO843004A NO163814C (no) 1983-07-25 1984-07-24 Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-substituerte 4-hydroksymetyl-pyrrolidinon-derivater.

Country Status (24)

Country Link
US (1) US4581364A (da)
EP (1) EP0132811B1 (da)
JP (1) JPS6051172A (da)
KR (1) KR910003613B1 (da)
AT (1) ATE37537T1 (da)
AU (1) AU568863B2 (da)
CA (1) CA1253159A (da)
CS (1) CS244447B2 (da)
DD (1) DD233125A5 (da)
DE (2) DE3326724A1 (da)
DK (1) DK362584A (da)
ES (1) ES8602649A1 (da)
FI (1) FI78463C (da)
GR (1) GR82221B (da)
HU (1) HU192039B (da)
IL (1) IL72477A (da)
NO (1) NO163814C (da)
NZ (1) NZ208990A (da)
PH (1) PH21119A (da)
PL (1) PL142583B1 (da)
PT (1) PT78968B (da)
SU (1) SU1498385A3 (da)
YU (1) YU42901B (da)
ZA (1) ZA845697B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel
JPH066571B2 (ja) * 1985-05-09 1994-01-26 エーザイ株式会社 2−ピロリドン誘導体
US4700244A (en) * 1986-02-14 1987-10-13 Hewlett-Packard Company Process and system for compensating for information shifts on disc storage media
DE3706399A1 (de) * 1987-02-27 1988-09-08 Boehringer Ingelheim Kg Mittel mit antidepressiver wirkung
US4981974A (en) * 1989-05-08 1991-01-01 Gaf Chemicals Corporation Polymerizable pyrrolidonyl oxazoline monomers
IT1231921B (it) * 1989-06-12 1992-01-15 Sigma Tau Ind Farmaceuti 1-acil-2-pirrolidoni quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti
IT1231477B (it) * 1989-07-12 1991-12-07 Sigma Tau Ind Farmaceuti (pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti
EP0420438B1 (en) * 1989-09-29 1996-03-13 Seagate Technology International A method of and apparatus for detecting position error of a transducer
AU2012284000A1 (en) * 2011-07-21 2014-02-06 The Lubrizol Corporation Overbased friction modifiers and methods of use thereof
JP6054390B2 (ja) * 2011-07-21 2016-12-27 ザ ルブリゾル コーポレイションThe Lubrizol Corporation カルボン酸ピロリジノンおよびその使用方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
DE2454325A1 (de) * 1974-11-15 1976-05-20 Bayer Ag Zusatzbeschleuniger enthaltende ungesaettigte polyesterharze
US4119637A (en) * 1975-09-23 1978-10-10 A. H. Robins Company, Inc. 4-Hydroxymethyl-2-pyrrolidinones
JPS5246067A (en) * 1975-10-07 1977-04-12 Teijin Ltd Reduction of optically active 5-oxo-2-pyrrolidinacetic acid esters
US4144245A (en) * 1977-05-11 1979-03-13 A. H. Robins Company, Inc. 4-Hydroxymethyl-2-pyrrolidinones
DE2757680A1 (de) * 1977-12-23 1979-06-28 Troponwerke Gmbh & Co Kg Neue 2-oxo-1-pyrrolidinessigsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
DE2923975A1 (de) * 1979-06-13 1980-12-18 Nattermann A & Cie Pyrrolidinone, verfahren zu deren herstellung und diese enthaltende arzneimittel
CH657527A5 (de) * 1980-02-13 1986-09-15 Ciba Geigy Ag Verwendung von zentralnervoes-wirksamen verbindungen in einem mittel, welches zur verhinderung oder linderung von nebenwirkungen bestimmt ist.
DE3031118A1 (de) * 1980-08-18 1982-04-01 Meditest Institut für medizinisch-pharmazeutische Untersuchungen GmbH & Co KG, 7958 Laupheim N,n'-bis(5-oxo-1-methyl-pyrrolidin-2-yl-essigsaeure)-hydrazid, verfahren zu dessen herstellung und seine verwendung als arzneimittel
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel

Also Published As

Publication number Publication date
CS244447B2 (en) 1986-07-17
HU192039B (en) 1987-04-28
GR82221B (da) 1984-12-13
PL142583B1 (en) 1987-11-30
IL72477A (en) 1988-02-29
YU130884A (en) 1986-10-31
FI78463C (fi) 1989-08-10
NZ208990A (en) 1987-10-30
PL248898A1 (en) 1985-07-16
DE3326724A1 (de) 1985-02-07
DE3474300D1 (en) 1988-11-03
US4581364A (en) 1986-04-08
PT78968B (de) 1986-10-21
SU1498385A3 (ru) 1989-07-30
IL72477A0 (en) 1984-11-30
HUT36454A (en) 1985-09-30
PH21119A (en) 1987-07-27
KR910003613B1 (ko) 1991-06-07
FI78463B (fi) 1989-04-28
JPH0463872B2 (da) 1992-10-13
JPS6051172A (ja) 1985-03-22
EP0132811A1 (de) 1985-02-13
YU42901B (en) 1988-12-31
NO843004L (no) 1985-01-28
DD233125A5 (de) 1986-02-19
ES534587A0 (es) 1985-12-01
FI842955A0 (fi) 1984-07-25
DK362584D0 (da) 1984-07-24
AU568863B2 (en) 1988-01-14
CA1253159A (en) 1989-04-25
CS571084A2 (en) 1985-08-15
DK362584A (da) 1985-01-26
NO163814B (no) 1990-04-17
ZA845697B (en) 1986-03-26
PT78968A (de) 1984-08-01
AU3110184A (en) 1985-01-31
EP0132811B1 (de) 1988-09-28
KR850001166A (ko) 1985-03-16
ATE37537T1 (de) 1988-10-15
ES8602649A1 (es) 1985-12-01
FI842955A (fi) 1985-01-26

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