ZA845697B - Pyrrolidinone derivatives,processes for their preparation,and pharmaceutical compositions containing them - Google Patents

Pyrrolidinone derivatives,processes for their preparation,and pharmaceutical compositions containing them

Info

Publication number
ZA845697B
ZA845697B ZA845697A ZA845697A ZA845697B ZA 845697 B ZA845697 B ZA 845697B ZA 845697 A ZA845697 A ZA 845697A ZA 845697 A ZA845697 A ZA 845697A ZA 845697 B ZA845697 B ZA 845697B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
pyrrolidinone derivatives
Prior art date
Application number
ZA845697A
Other languages
English (en)
Inventor
Karl-Heinz Weber
Gerhard Walther
Claus Schneider
Dieter Hinzen
Franz Josef Kuhn
Erich Lehr
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ZA845697B publication Critical patent/ZA845697B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
ZA845697A 1983-07-25 1984-07-24 Pyrrolidinone derivatives,processes for their preparation,and pharmaceutical compositions containing them ZA845697B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833326724 DE3326724A1 (de) 1983-07-25 1983-07-25 In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte

Publications (1)

Publication Number Publication Date
ZA845697B true ZA845697B (en) 1986-03-26

Family

ID=6204831

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA845697A ZA845697B (en) 1983-07-25 1984-07-24 Pyrrolidinone derivatives,processes for their preparation,and pharmaceutical compositions containing them

Country Status (24)

Country Link
US (1) US4581364A (xx)
EP (1) EP0132811B1 (xx)
JP (1) JPS6051172A (xx)
KR (1) KR910003613B1 (xx)
AT (1) ATE37537T1 (xx)
AU (1) AU568863B2 (xx)
CA (1) CA1253159A (xx)
CS (1) CS244447B2 (xx)
DD (1) DD233125A5 (xx)
DE (2) DE3326724A1 (xx)
DK (1) DK362584A (xx)
ES (1) ES534587A0 (xx)
FI (1) FI78463C (xx)
GR (1) GR82221B (xx)
HU (1) HU192039B (xx)
IL (1) IL72477A (xx)
NO (1) NO163814C (xx)
NZ (1) NZ208990A (xx)
PH (1) PH21119A (xx)
PL (1) PL142583B1 (xx)
PT (1) PT78968B (xx)
SU (1) SU1498385A3 (xx)
YU (1) YU42901B (xx)
ZA (1) ZA845697B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel
JPH066571B2 (ja) * 1985-05-09 1994-01-26 エーザイ株式会社 ２−ピロリドン誘導体
US4700244A (en) * 1986-02-14 1987-10-13 Hewlett-Packard Company Process and system for compensating for information shifts on disc storage media
DE3706399A1 (de) * 1987-02-27 1988-09-08 Boehringer Ingelheim Kg Mittel mit antidepressiver wirkung
US4981974A (en) * 1989-05-08 1991-01-01 Gaf Chemicals Corporation Polymerizable pyrrolidonyl oxazoline monomers
IT1231921B (it) * 1989-06-12 1992-01-15 Sigma Tau Ind Farmaceuti 1-acil-2-pirrolidoni quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti
IT1231477B (it) * 1989-07-12 1991-12-07 Sigma Tau Ind Farmaceuti (pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti
EP0420438B1 (en) * 1989-09-29 1996-03-13 Seagate Technology International A method of and apparatus for detecting position error of a transducer
CN103814011B (zh) * 2011-07-21 2017-02-08 路博润公司 过碱性摩擦改进剂及其使用方法
JP6054390B2 (ja) * 2011-07-21 2016-12-27 ザ ルブリゾル コーポレイションＴｈｅ Ｌｕｂｒｉｚｏｌ Ｃｏｒｐｏｒａｔｉｏｎ カルボン酸ピロリジノンおよびその使用方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1039113A (en) * 1964-08-06 1966-08-17 Ucb Sa New n-substituted lactams
DE2454325A1 (de) * 1974-11-15 1976-05-20 Bayer Ag Zusatzbeschleuniger enthaltende ungesaettigte polyesterharze
US4119637A (en) * 1975-09-23 1978-10-10 A. H. Robins Company, Inc. 4-Hydroxymethyl-2-pyrrolidinones
JPS5246067A (en) * 1975-10-07 1977-04-12 Teijin Ltd Reduction of optically active 5-oxo-2-pyrrolidinacetic acid esters
US4144245A (en) * 1977-05-11 1979-03-13 A. H. Robins Company, Inc. 4-Hydroxymethyl-2-pyrrolidinones
DE2757680A1 (de) * 1977-12-23 1979-06-28 Troponwerke Gmbh & Co Kg Neue 2-oxo-1-pyrrolidinessigsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
DE2923975A1 (de) * 1979-06-13 1980-12-18 Nattermann A & Cie Pyrrolidinone, verfahren zu deren herstellung und diese enthaltende arzneimittel
CH657527A5 (de) * 1980-02-13 1986-09-15 Ciba Geigy Ag Verwendung von zentralnervoes-wirksamen verbindungen in einem mittel, welches zur verhinderung oder linderung von nebenwirkungen bestimmt ist.
DE3031118A1 (de) * 1980-08-18 1982-04-01 Meditest Institut für medizinisch-pharmazeutische Untersuchungen GmbH & Co KG, 7958 Laupheim N,n'-bis(5-oxo-1-methyl-pyrrolidin-2-yl-essigsaeure)-hydrazid, verfahren zu dessen herstellung und seine verwendung als arzneimittel
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel

Also Published As

Publication number Publication date
SU1498385A3 (ru) 1989-07-30
HU192039B (en) 1987-04-28
ES8602649A1 (es) 1985-12-01
FI78463C (fi) 1989-08-10
FI842955A0 (fi) 1984-07-25
YU42901B (en) 1988-12-31
EP0132811B1 (de) 1988-09-28
CS244447B2 (en) 1986-07-17
YU130884A (en) 1986-10-31
NZ208990A (en) 1987-10-30
PL248898A1 (en) 1985-07-16
PL142583B1 (en) 1987-11-30
PT78968B (de) 1986-10-21
KR910003613B1 (ko) 1991-06-07
DK362584D0 (da) 1984-07-24
CA1253159A (en) 1989-04-25
NO163814C (no) 1990-07-25
PT78968A (de) 1984-08-01
ATE37537T1 (de) 1988-10-15
US4581364A (en) 1986-04-08
AU568863B2 (en) 1988-01-14
NO843004L (no) 1985-01-28
FI842955A (fi) 1985-01-26
AU3110184A (en) 1985-01-31
CS571084A2 (en) 1985-08-15
DK362584A (da) 1985-01-26
PH21119A (en) 1987-07-27
HUT36454A (en) 1985-09-30
IL72477A (en) 1988-02-29
ES534587A0 (es) 1985-12-01
IL72477A0 (en) 1984-11-30
JPS6051172A (ja) 1985-03-22
EP0132811A1 (de) 1985-02-13
GR82221B (xx) 1984-12-13
FI78463B (fi) 1989-04-28
KR850001166A (ko) 1985-03-16
DE3474300D1 (en) 1988-11-03
DD233125A5 (de) 1986-02-19
NO163814B (no) 1990-04-17
JPH0463872B2 (xx) 1992-10-13
DE3326724A1 (de) 1985-02-07

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